المؤلفون: Hongquan Guo, Xinfeng Liu, Juanji Li, Xiaolei Shi, Yi Xie, Pengfei Xu, Yunzi Li, Qian Liu, Rui Sun, Ye Hong, Mengna Peng, Gelin Xu

المصدر: Redox Biology
Redox Biology, Vol 18, Iss, Pp 158-172 (2018)

مصطلحات موضوعية: 0301 basic medicine, BRCT, BRCA1 C-terminal, GPX3, glutathione peroxidase 3, 4-HNE, 4-hydroxynonenol, OGD, oxygen-glucose deprivation, GCLM, glutamate-cysteine ligase regulator subunit, Iba-1, ionized calcium-binding adapter molecule-1, Clinical Biochemistry, SOD1, superoxide dismutase 1, HO-1, heme oxygenase 1, medicine.disease_cause, Biochemistry, NPCs, neural precursor cells, CaMKII, calcium/calmodulin-dependent protein kinase II, Lipid peroxidation, chemistry.chemical_compound, CA1, cornu ammonis 1, NSCs, neural stem cells, 3-NT, 3-nitrotyrosine, XRE, xenobiotic responsive element, skin and connective tissue diseases, lcsh:QH301-705.5, BER, base excision repair, GFP, green fluorescent protein, PSD95, postsynaptic density protein 95, chemistry.chemical_classification, lcsh:R5-920, DCX, doublecortin, ALS, amyotrophic lateral sclerosis, NRF2, nuclear factor (erythroid-derived 2)-like 2, GPX4, glutathione peroxidase 4, 8-OHDG, 8-hydroxy-2′-deoxyguanosine, Signal transduction, lcsh:Medicine (General), Ischemia/Reperfusion, Research Paper, NQO1, NAD(P)H dehydrogenase (quinone 1), DNA damage, DNA repair, Ischemia, I/R, ischemia/reperfusion, CNS, central nervous system, GCLC, glutamate-cysteine ligase catalytic, NRF2, 03 medical and health sciences, ROS, reactive oxygen species, NER, nucleotide excision repair, medicine, MCAO, middle cerebral artery occlusion, SOD2, superoxide dismutase 2, Reactive oxygen species, AD, Alzheimer disease, Organic Chemistry, GFAP, glial fibrillary acidic protein, BRCA1, medicine.disease, ARE, antioxidative response element, 030104 developmental biology, lcsh:Biology (General), chemistry, NHEJ, non-homologous end joining, Oxidative stress, BRCA1, breast cancer susceptibility protein 1, DSBs, double strand breaks, Cancer research, HR, homologous recombination, Reperfusion injury

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e034e7c5102b1e7cd98f372f511aacTest
https://doi.org/10.1016/j.redox.2018.06.012Test

المؤلفون: Anja A. Kühl, Monique R. Bernsen, Winfried Brenner, M. Welzel, Richard P. Baum, Samantha Exner, Eva J. Koziolek, Jakob Albrecht, Dagmar Sedding, Patricia Grabowski, Christian Fischer, Fränze Schmidt, Teresa Hartung, Joost C. Haeck, Franziska Briest, Carsten Grötzinger

المساهمون: Radiology & Nuclear Medicine

المصدر: Neoplasia (New York, N.Y.)
BASE-Bielefeld Academic Search Engine
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 80-98 (2021)
Neoplasia (United States), 23(1), 80-98

مصطلحات موضوعية: Apoptosis, FOXO3a, forkheadbox protein O3a, d, day(s), Rb, retinoblastoma protein, Mice, 0302 clinical medicine, JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide, Molecular Targeted Therapy, BER, base excision repair, Bortezomib, IC50, dose of half-maximum inhibitory effect, Ga-68, Gallium-68, Drug Synergism, DSMZ, Deutsche Sammlung für Mikroorganismen und Zellen, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Neuroendocrine Tumors, G0/1/2 phase, gap phase 0/1/2, 030220 oncology & carcinogenesis, CAM, chorioallantoic membrane, (M)Bq, (Mega-)Becquerel, Original article, PRRT, peptide receptor radionuclide therapy, DNA damage, p70S6K, ribosomal protein S6 kinase, DNA repair, Antineoplastic Agents, NEN, neuroendocrine neoplasms, ERK, extracellular-signal-regulated kinase, lcsh:RC254-282, AP-sides, apurinic or apyrimidinic sites, M phase, mitosis phase, 03 medical and health sciences, SDG 3 - Good Health and Well-being, In vivo, i.v., intravenous, NER, nucleotide excision repair, GO, Gene Ontology, Humans, Combination therapy, FOXM1, forkheadbox protein M1, Cisplatin, G1/2/3, grade 1/2/3, Dose-Response Relationship, Drug, Proteasome inhibition, Cell Cycle Checkpoints, n, number, H2AX, histone H2AX, 030104 developmental biology, Proteasome, NHEJ, non-homologous end joining, g, gram, Proteasome inhibitor, HR, homologous recombination, 0301 basic medicine, Cancer Research, BRIP1, BRCA1 Interacting Protein C-Terminal Helicase 1, Chick Embryo, RPA, replication protein A, GEP-NEN, gastroenteropancreatic neuroendocrine neoplasms, SCLC, small cell lung cancer, Gene Regulatory Networks, TGF, transforming growth factor, HTCA, human tumor colony assay, Gastrointestinal Neoplasms, i.p., intraperitoneal, M, molar, Lu-177, Lutetium-177, Proteasome Inhibitors, F-18-FDG-PET, 2-deoxy-2-(F-18)fluoro-D-glucose positron emission tomography, SSTR2, somatostatin receptor 2, PI3K, phosphoinositide 3-kinase, medicine.drug, DDR, DNA damage repair, MMR, mismatch repair, SKP2, S-Phase Kinase Associated Protein 2, PARP1, poly(ADP-ribose) polymerase 1, (RT)-PCR, (real-time) polymerase chain reaction, BRCA1/2, breast cancer protein 1/2, ER, endoplasmic reticulum, ROS, reactive oxygen species, S phase, synthesis phase, Cell Line, Tumor, h, hour(s), medicine, Animals, TLS, translesion synthesis, Cell Proliferation, business.industry, DSB, double-strand breaks, PTEN, phosphatase and tensin homolog, CK2, casein kinase 2, Drug Resistance, Neoplasm, Radionuclide therapy, SSB, single-strand breaks, Cancer research, business, MRI, magnetic resonance imaging, DNA Damage, Peptide receptor radionuclide therapy (PRRT)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b0fcaaba5da9ca61e63d327232b0b4Test
http://www.scopus.com/inward/record.url?scp=85096683387&partnerID=8YFLogxKTest

المؤلفون: Ryohei Yasuda, Hirofumi Nishizono, Tal Laviv

المصدر: Frontiers in Genome Editing, Vol 2 (2020)
Frontiers in Genome Editing

مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, Transgene, lcsh:Biotechnology, Computational biology, Review, Biology, Synapse, 03 medical and health sciences, 0302 clinical medicine, Genome editing, lcsh:TP248.13-248.65, CRISPR, Genome Editing, HDR (homology-directed repair), Cas9, HITI (homology-independent targeted integration), Mammalian brain, lcsh:Genetics, 030104 developmental biology, NHEJ (non-homologous end joining), Cell bodies, SLENDR (single-cell labeling of endogenous proteins with homology-directed repair), 030217 neurology & neurosurgery, Function (biology), iGONAD (improved-genome editing via oviductal nucleic acids delivery)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027c58a5665dd5ba08f49e23d2a47fe5Test
https://www.frontiersin.org/articles/10.3389/fgeed.2020.602970/fullTest

المؤلفون: Lauren Milac, Casey D. Stefanski, Kaitlyn Keffler, Jenifer R. Prosperi, Stephanie McClintock

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 12, Pp 1143-1150 (2019)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, DNA Repair, ER, estrogen receptor, DNA Repair Inhibition, medicine.medical_treatment, Apoptosis, Chk2, checkpoint kinase 2, Targeted therapy, PyMT, polyoma middle T antigen, Mice, 0302 clinical medicine, Medicine, HER2, human epidermal growth factor, Triple-negative breast cancer, SSBs, single stranded breaks, TNBC, triple negative breast cancer, Mammary tumor, ATM, ataxia telangiectasia mutated, biology, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Chk1, checkpoint kinase 1, 3. Good health, 030220 oncology & carcinogenesis, Female, medicine.drug, Signal Transduction, Original article, Genes, APC, DNA damage, Adenomatous polyposis coli, DNA repair, CC3, cleaved caspase 3, DSBs, double stranded breaks, Breast Neoplasms, lcsh:RC254-282, Etop, etoposide, Topo IIα, topoisomerase IIα, 03 medical and health sciences, DNA-PK, DNA-dependent protein kinase, Cell Line, Tumor, Animals, Humans, STAT3, activation of signal transducer and activation of transcription 3, Doxorubicin, APC, Adenomatous Polyposis Coli, Cell Proliferation, business.industry, CIS, cisplatin, PR, progesterone receptor, DOX, doxorubicin, PTX, paclitaxel, 030104 developmental biology, Drug Resistance, Neoplasm, NHEJ, non-homologous end joining, Cancer research, biology.protein, ATR, ataxia telangiectasia and Rad3 related, H2AX, histone 2AX, business, HRR, homologous recombination repair, Gene Deletion, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369502e33e9032d8e43fcc56f9429f59Test
https://pubmed.ncbi.nlm.nih.gov/31759252Test

المؤلفون: Sabine Schmitz, Yvonne Lorat, Nadine Schuler, Claudia E. Rübe, Jan Palm

المصدر: Clinical and translational radiation oncology 7, 71-78 (2017). doi:10.1016/j.ctro.2017.10.004
Clinical and Translational Radiation Oncology
Clinical and Translational Radiation Oncology, Vol 7, Iss, Pp 71-78 (2017)

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Genomic instability, Pathology, medicine.medical_specialty, DNA repair, DNA damage, R895-920, Craniospinal Irradiation, Article, Medical physics. Medical radiology. Nuclear medicine, 03 medical and health sciences, Germline mutation, LFS, Li-Fraumeni syndrome, medicine, Radiology, Nuclear Medicine and imaging, SEM, scanning electron microscopy, Li-Fraumeni syndrome, ddc:610, TEM, transmission electron microscopy, DSBs, double-strands breaks, RC254-282, P53, business.industry, CPC, choroid plexus carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cancer, Craniospinal irradiation, medicine.disease, 53BP1, 53 Binding Protein 1, Hematopoiesis, NHEJ, non-homologous end-joining, γH2AX, phosporylated histone H2AX, 030104 developmental biology, medicine.anatomical_structure, Oncology, Li–Fraumeni syndrome, mFISH, multicolour fluorescence in-situ hybridization, Bone marrow, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03caa63d129c0cc1496a9436a5e3c549Test
https://juser.fz-juelich.de/record/839969Test

المؤلفون: Bryce W.Q. Tan, Upadhyayula Sai Srinivas, Anand D. Jeyasekharan, Balamurugan A. Vellayappan

المصدر: Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: MRN, Mre11-Rad50-Nbs1, 0301 basic medicine, DNA Repair, medicine.medical_treatment, Clinical Biochemistry, Mdm2, Mouse double minute 2, Apoptosis, H2O2, Hydrogen peroxide, Genotoxic Stress, DNA damage response, Biochemistry, SOD, Superoxide dismutase, 0302 clinical medicine, Neoplasms, HER-2, human epidermal growth factor receptor 2, lcsh:QH301-705.5, ATRIP, ATR interacting protein, Double strand, chemistry.chemical_classification, lcsh:R5-920, Chemistry, OXPHOS, Oxidative phosphorylation, ROS, Cdc25, Cell division cycle 25, dNTP, deoxyribonucleotide triphosphate, PLK1, Polo-like kinase 1, BER, Base excision repair, NADPH, Nicotinamide adenine dinucleotide phosphate, ICD, Immunogenic cell death, lcsh:Medicine (General), BSO, Buthionine sulfoximine, ATM, Ataxia telangiectasia mutated, DNA damage, NRF-2, Nuclear factor (erythroid-derived 2)-like 2, ATR, Ataxia telangiectasia mutated and Rad3 related, HR, Homologous recombination, Context (language use), DDR, Article, DDR, DNA damage response, 03 medical and health sciences, RPA, Replication protein A, medicine, Animals, Humans, Chemotherapy, MAPK, Mitogen-activated protein kinases, NCF2, Neutrophil Cytosolic Factor 2, Reactive oxygen species, PPP, Pentose phosphate pathway, XRCC4, X-ray repair cross-complementing protein 4, Radiotherapy, DNA PK, DNA-dependent protein kinase, Organic Chemistry, Cancer, NHEJ, Non-homologous end joining, medicine.disease, ETC, Electron transport chain, mtROS, Mitochondrial ROS, Radiation therapy, DSB, Double strand break, 030104 developmental biology, lcsh:Biology (General), AML, Acute myeloid leukemia, Cancer research, Tumor Suppressor Protein p53, Reactive Oxygen Species, 030217 neurology & neurosurgery, DNA Damage, ROS, Reactive oxygen species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88506b3a62a7fc5a96ea3bf0d616e55eTest
https://doi.org/10.1016/j.redox.2018.101084Test

المؤلفون: Aaron Wilson, Vijay Menon, Asim Alam, Larisa Litovchick, Vasily A. Yakovlev, Zubair Khan

المصدر: Redox Biology
Redox Biology, Vol 24, Iss, Pp-(2019)

مصطلحات موضوعية: 0301 basic medicine, Synthetic lethality, DNA Repair, medicine.medical_treatment, Clinical Biochemistry, Radiation Tolerance, Biochemistry, Ionizing radiation, 0302 clinical medicine, Radiation, Ionizing, lcsh:QH301-705.5, PARP inhibitors, BER, base excision repair, Sensitization, lcsh:R5-920, BRCA1 Protein, Chemistry, MTM, mean tail moment, BRCA, breast cancer type susceptibility proteins, medicine.anatomical_structure, Homologous recombination repair, PARP inhibitor, FITC, fluorescein isothiocyanate, lcsh:Medicine (General), Research Paper, PARP, poly (ADP-ribose) polymerase, Signal Transduction, PARPi, poly (ADP-ribose) polymerase inhibitor, DNA damage, Nitric oxide donors, MMR, mismatch repair, SSB, single-strand break, Poly(ADP-ribose) Polymerase Inhibitors, 03 medical and health sciences, NER, nucleotide excision repair, Cell Line, Tumor, RBL2, Retinoblastoma-like protein 2, medicine, Humans, DSB, double-strand break, Edetic Acid, Tumor microenvironment, Chemotherapy, Retinoblastoma-Like Protein p130, Organic Chemistry, PI, Propidium Iodide, Cancer, medicine.disease, 030104 developmental biology, lcsh:Biology (General), NHEJ, non-homologous end joining, Cancer research, IR, ionizing radiation, Benzimidazoles, HRR, homologous recombination repair, SD, standard deviation, Synthetic Lethal Mutations, 030217 neurology & neurosurgery, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1895e2b42e85aea0604778704956607Test
https://doi.org/10.1016/j.redox.2019.101169Test