نتائج البحث

1

Evaluation of serological lateral flow assays for severe acute respiratory syndrome coronavirus-2

المؤلفون: James A. Toombs, David R. Walt, Yikai Kuo, Glenn A Miller, Unnati M. Pandya, Christina Samaha, Christopher E. Ramirez, Santiago Pardo, Esmarline J. De Leon Peralta, Gerald F. Watts, Rocky Barilla, Robert R. Kitchen, Brooke Fortin, Daimon P. Simmons, Rebecca C. Larson, Anna Bolling, Vannessa M. Davis, Samuel Bates, Rushdy Ahmad, Jina Ko, Melissa Bedard, Tal Gilboa, Hayden Ventresca, Becky C. Carlyle, Benjamin Nicholson, Pierre Cunin, Sally Zhou, Bianca A. Trombetta, Edmond Wong, Sara Yohannes, Aditi Hazra, Shibani S. Mukerji, Petr Jarolim, Chevaun Morrison-Smith, Charles Jennings, Samara Maxine Miller, Haley M. Pleskow, Pushpamali De Silva, Emma Gomez-Rivas, Michael Kann, Thadryan Sweeney, Wen Zhou, Catherine Fink, Pia Kivisakk Webb, Megan Kwock, Nell Meosky Luo, Leo L. Cheng, Sejal Jain, Maia Norman, Jacqueline M. Slavik, Lauren L. Ritterhouse, Zakary Ganhadeiro, Leena El-Mufti, Jianing Wang, Savannah E. Kandigian, Korneel Grauwet, Sara Suliman

المصدر: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-14 (2021)
BMC Infectious Diseases

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Prevalence, Infectious and parasitic diseases, RC109-216, Antibodies, Viral, medicine.disease_cause, Sensitivity and Specificity, Gastroenterology, Immunoglobulin G, Antibodies, COVID-19 Serological Testing, Serology, User-Computer Interface, 03 medical and health sciences, 0302 clinical medicine, Limit of Detection, Predictive Value of Tests, Internal medicine, medicine, Humans, 030212 general & internal medicine, Aged, Coronavirus, Lateral flow assays, biology, medicine.diagnostic_test, business.industry, SARS-CoV-2, Research, Correction, COVID-19, Middle Aged, 030104 developmental biology, Infectious Diseases, Immunoglobulin M, Parasitology, Immunoassay, Predictive value of tests, biology.protein, Female, business, User-Centered Design

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4808b1cf00a72167d2804a3b5c70d98cTest
https://doaj.org/article/019aff5557364e74bdca28b0b1adff41Test

2

FGF18–FGFR2 signaling triggers the activation of c-Jun–YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential

المؤلفون: Jinglin Zhang, Hui Li, William K.K. Wu, Liping Liu, Kam Tong Leung, Ronald C. K. Chan, Alfred S. L. Cheng, Ka F. To, Nathalie Wong, Wei Kang, Kwok Wai Lo, Joanna H.M. Tong, Michael W.Y. Chan, Chi Chun Wong, Yuhang Zhou, Feng Wu, Yifei Wang, Huan Yan, Jun Yu

المصدر: Oncogene

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Carcinogenesis, Proto-Oncogene Proteins c-jun, Datasets as Topic, Kaplan-Meier Estimate, medicine.disease_cause, Piperazines, Tumour biomarkers, Cohort Studies, Mice, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, RNA-Seq, YAP1, Gene knockdown, integumentary system, c-jun, Middle Aged, Prognosis, Progression-Free Survival, Up-Regulation, Gene Expression Regulation, Neoplastic, Fibroblast growth factor receptor, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, embryonic structures, Benzamides, Female, Signal transduction, musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, DNA Copy Number Variations, MAP Kinase Signaling System, Biology, Article, 03 medical and health sciences, Downregulation and upregulation, Stomach Neoplasms, Cell Line, Tumor, Genetics, medicine, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 2, Molecular Biology, Adaptor Proteins, Signal Transducing, Neoplasm Staging, Growth factor signalling, Verteporfin, YAP-Signaling Proteins, FGF18, Xenograft Model Antitumor Assays, Fibroblast Growth Factors, stomatognathic diseases, 030104 developmental biology, Cancer research, Pyrazoles, Gastric cancer, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c392569ea8d6f34c85fefdb375cd32Test
https://doi.org/10.1038/s41388-020-01458-xTest

3

A unified framework for integrative study of heterogeneous gene regulatory mechanisms

المؤلفون: Alfred S. L. Cheng, Kevin Y. Yip, Eric Lo, Chao Cheng, Qiong Wu, Zhenghao Zhang, Alexander Xi Fu, Danny Leung, Tin-Lap Lee, Qin Cao

المصدر: Nature Machine Intelligence. 2:447-456

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::05b7cba3f8ca6565fd688edaac9b5d6fTest
https://doi.org/10.1038/s42256-020-0205-2Test

4

Bufalin inhibits hepatitis B virus-associated hepatocellular carcinoma development through androgen receptor dephosphorylation and cell cycle-related kinase degradation

المؤلفون: Xue-Hua Sun, Hai Feng, Zhuo Yu, Xiao-Jun Zhu, Lingying Huang, Dae-Yeul Yu, Alfred S. L. Cheng, Yueqiu Gao, Fan Le, Zhen-Hua Zhou, Xin Zhang, Yunhui Zhuo, Chao Zheng, Man Li, Yun Jiang

المصدر: Cellular Oncology. 43:1129-1145

مصطلحات موضوعية: 0301 basic medicine, Hepatitis B virus, Cancer Research, Carcinoma, Hepatocellular, Cell cycle checkpoint, Carcinogenesis, Cell, Mice, Nude, Mice, Transgenic, Models, Biological, 03 medical and health sciences, 0302 clinical medicine, Cyclin D1, Cell Line, Tumor, medicine, Animals, Viral Regulatory and Accessory Proteins, Phosphorylation, beta Catenin, Cell Proliferation, Glycogen Synthase Kinase 3 beta, Kinase, Chemistry, Liver Neoplasms, Bufalin, Cell Cycle Checkpoints, General Medicine, Sorafenib, Cell cycle, Cyclin-Dependent Kinases, digestive system diseases, Bufanolides, Androgen receptor, HBx, 030104 developmental biology, medicine.anatomical_structure, Oncology, Receptors, Androgen, 030220 oncology & carcinogenesis, Proteolysis, Trans-Activators, Cancer research, Molecular Medicine, Cyclin-Dependent Kinase-Activating Kinase, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55251d8d5c8f54041ae8eab25a5b32bTest
https://doi.org/10.1007/s13402-020-00546-0Test

5

AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis

المؤلفون: Ka Fai To, Jun Yu, Tingting Huang, Patrick Ming-Kuen Tang, Yuhang Zhou, Kwok Wai Lo, Jinglin Zhang, Liping Liu, Feng Wu, Chi Chun Wong, Nuoqing Weng, Nathalie Wong, Man Wu, Wei Kang, Alfred S. L. Cheng, Hui Li

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Kaplan-Meier Estimate, medicine.disease_cause, Tumour biomarkers, Mice, 0302 clinical medicine, RNA, Small Interfering, Regulation of gene expression, YAP1, Recombinant Proteins, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Cell Transformation, Neoplastic, Hippo signaling, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Heterografts, RNA Interference, Signal transduction, Protein Binding, Signal Transduction, Proteasome Endopeptidase Complex, Active Transport, Cell Nucleus, Antineoplastic Agents, Biology, Protein Serine-Threonine Kinases, Article, 03 medical and health sciences, Downregulation and upregulation, Stomach Neoplasms, Cell Line, Tumor, Genetics, medicine, Animals, Humans, Hippo Signaling Pathway, Molecular Biology, Adaptor Proteins, Signal Transducing, Cell Nucleus, Protein transport, Connective Tissue Growth Factor, Membrane Proteins, Verteporfin, YAP-Signaling Proteins, Angiomotin, CTGF, 030104 developmental biology, Angiomotins, Cancer research, Carcinogenesis, Gastric cancer, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbfb8b46ff4fb2c6dd9b605bd96dd0cTest
http://europepmc.org/articles/PMC7253359Test

6

Autism‐associated PTEN missense mutation leads to enhanced nuclear localization and neurite outgrowth in an induced pluripotent stem cell line

المؤلفون: Alfred S. L. Cheng, Lisha Li, Tian Liu, Stanley K.K. Cheung, Bo Feng, J. P. H. Burbach, Yubing Wang, Andrew K Chan, Raymond Chuen-Chung Chang, Chi Wai Wong, Kwong Wai Choy, Penelope M.Y. Or

المصدر: The Febs Journal

مصطلحات موضوعية: 0301 basic medicine, PTEN, Autism Spectrum Disorder, autism spectrum disorders, Blotting, Western, Induced Pluripotent Stem Cells, Neuronal Outgrowth, Mutant, Mutation, Missense, Phosphatidate Phosphatase, macrocephaly, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, Cell Line, Tumor, Humans, Missense mutation, Phosphorylation, Progenitor cell, Induced pluripotent stem cell, Molecular Biology, C2 domain, Cell Nucleus, biology, Protein Stability, Chemistry, neurodevelopmental disorders, PTEN Phosphohydrolase, Cell Biology, Cell biology, Editor's Choice, HEK293 Cells, 030104 developmental biology, 030220 oncology & carcinogenesis, PC-3 Cells, biology.protein, PTEN hamartoma tumor syndrome, Nuclear localization sequence

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570784f30faa19aa38d2ac2db4730bafTest
https://doi.org/10.1111/febs.15287Test

7

Abstract P2-13-02: Chemotherapy-related amenorrhea (CRA) after adjuvant trastuzumab emtansine (T-DM1) compared to paclitaxel in combination with trastuzumab (TH) (TBCRC033: ATEMPT trial)

المصدر: Cancer Research. 80:P2-13

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::15d0d297ed01e27f0feaa7d331abee35Test
https://doi.org/10.1158/1538-7445.sabcs19-p2-13-02Test

8

Absolute lymphocyte count as a prognostic biomarker for overall survival in patients with advanced melanoma treated with ipilimumab

المؤلفون: Deborah Kuk, Michael L. Cheng, Jianda Yuan, Katherine S. Panageas, Scott D. Chasalow, Michael A. Postow, Jedd D. Wolchok

المصدر: Melanoma Res

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83df1610b28b7f86546beaaf1f022b97Test
https://doi.org/10.1097/cmr.0000000000000633Test

9

Lipid droplet velocity is a microenvironmental sensor of aggressive tumors regulated by V-ATPase and PEDF

المؤلفون: Kyrsten M Brooks, Kevin L Cheng, Michael A. Welte, Philip Fitchev, Francesca Nardi, Simon W. Hayward, Omar E. Franco, Susan E. Crawford

المصدر: Lab Invest

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d252bbf1c5e78bd7bf0deadd7c23f955Test
https://doi.org/10.1038/s41374-019-0296-8Test

10

Dysregulated Alanine as a Potential Predictive Marker of Glioma—An Insight from Untargeted HRMAS-NMR and Machine Learning Data

المؤلفون: Safia Firdous, Saima Sadaf, Zubair Nawaz, Rizwan Abid, Ammar Anwer, Leo L. Cheng, Faisal Bukhari

المصدر: Metabolites; Volume 11; Issue 8; Pages: 507
Metabolites, Vol 11, Iss 507, p 507 (2021)
Metabolites

مصطلحات موضوعية: 0301 basic medicine, Endocrinology, Diabetes and Metabolism, Metabolite, Biology, Machine learning, computer.software_genre, Logistic regression, Biochemistry, Microbiology, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, alanine, glioma, high-resolution magic angle spinning nuclear magnetic resonance spectroscopy (HRMAS-NMRS), untargeted metabolomics, machine learning, liquid biopsy, Glioma, medicine, Liquid biopsy, Molecular Biology, Alanine, Predictive marker, business.industry, medicine.disease, QR1-502, Random forest, Glutamine, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Artificial intelligence, business, computer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527d0a46bfe6f316bb043690b30dd3a4Test

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