نتائج البحث - "Insulin‐like growth factor I receptor"

1

Understanding the biology of HER3 receptor as a therapeutic target in human cancer

المؤلفون: Shuang Liu, Amy Han, Erik V. Polsdofer, Bolin Liu, Hui Lyu

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 8, Iss 4, Pp 503-510 (2018)

مصطلحات موضوعية: 0301 basic medicine, lncRNA, long ncRNA, Cell signaling, medicine.medical_treatment, Review, Ab, antibody, TKI, tyrosine kinase inhibitor, Receptor tyrosine kinase, Targeted therapy, IGF-1R, insulin-like growth factor-I receptor, 0302 clinical medicine, ADCC, antibody-dependent cell-mediated cytotoxicity, miRNA, microRNA, General Pharmacology, Toxicology and Pharmaceutics, skin and connective tissue diseases, ERBB4, biology, 3. Good health, 030220 oncology & carcinogenesis, RTK, receptor tyrosine kinase, EMT, epithelial-mesenchymal transition, Tyrosine kinase, Dimerization, Proto-oncogene tyrosine-protein kinase Src, PI-3K, phosphoinositide 3-kinase, OS, overall survival, 03 medical and health sciences, HER3, NSCLC, non-small cell lung cancer, medicine, PI3K/AKT/mTOR pathway, lcsh:RM1-950, MEK, MAPK kinase, Cancer, Therapeutic resistance, HER, Human epidermal growth factor receptor, medicine.disease, FDA, Food and Drug Administration, EGFR, epidermal growth factor receptor, body regions, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, biology.protein, Cancer research, HRG, heregulin, MAPK, mitogen-activated protein kinase, Tumor metastasis, ncRNA, noncoding RNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8246db5a34e15a38b4f6d0fe299e7ef7Test
http://europepmc.org/articles/PMC6090011Test

2

Bone Status in a Patient with Insulin-Like Growth Factor-1 Receptor Deletion Syndrome: Bone Quality and Structure Evaluation Using Dual-Energy X-Ray Absorptiometry, Peripheral Quantitative Computed Tomography, and Quantitative Ultrasonography

المؤلفون: Maurizio de Martino, Alberto Verrotti, Paola Pelosi, Elisabetta Lapi, Marilena Pantaleo, Loredana Cavalli, Stefano Stagi

المصدر: Frontiers in Endocrinology, Vol 8 (2017)
Frontiers in Endocrinology

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Pathology, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, insulin-like growth factor-I receptor, Case Report, 030209 endocrinology & metabolism, Biology, lcsh:Diseases of the endocrine glands. Clinical endocrinology, Short stature, Bone remodeling, 03 medical and health sciences, Insulin-like growth factor, Endocrinology, 0302 clinical medicine, Internal medicine, medicine, insulin-like growth factor-I, peripheral quantitative computed tomography, Quantitative computed tomography, Dual-energy X-ray absorptiometry, Bone metabolism, Insulin-like growth factor-I, Insulin-like growth factor-I receptor, Peripheral quantitative computed tomography, Quantitative ultrasonography, Insulin-like growth factor 1 receptor, lcsh:RC648-665, medicine.diagnostic_test, medicine.disease, quantitative ultrasonography, Uniparental disomy, 030104 developmental biology, bone metabolism, medicine.symptom, Haploinsufficiency

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250a27ba4e71ba2729783e661ee75024Test
https://doi.org/10.3389/fendo.2017.00227Test

3

IGF-I Induces Epithelial-to-Mesenchymal Transition via the IGF-IR‐Src‐MicroRNA-30a‐E-Cadherin Pathway in Nasopharyngeal Carcinoma Cells

المؤلفون: Heming Li, Wang Zhe, Xuefen Guo, Ruoyu Wang, Shanshan Liang, Chengxue Dang

المصدر: Oncology Research

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Epithelial-to-mesenchymal transition (EMT), medicine.medical_treatment, MicroRNA-30a (miR-30a), Biology, Article, Receptor, IGF Type 1, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, otorhinolaryngologic diseases, medicine, Carcinoma, Humans, Epithelial–mesenchymal transition, Insulin-Like Growth Factor I, Insulin-like growth factor I receptor (IGF-IR), Nasopharyngeal Carcinoma, Cadherin, Growth factor, Nasopharyngeal Neoplasms, Receptors, Somatomedin, General Medicine, Cadherins, medicine.disease, MicroRNAs, stomatognathic diseases, src-Family Kinases, 030104 developmental biology, Oncology, Nasopharyngeal carcinoma, 030220 oncology & carcinogenesis, Cancer research, Insulin-like growth factor I (IGF-I), Signal transduction, Src, Signal Transduction, Proto-oncogene tyrosine-protein kinase Src

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5224be27de44378f405767fe1e8e84b0Test
https://doi.org/10.3727/096504016x14648701447931Test

4

TAE226, a dual inhibitor of focal adhesion kinase and insulin-like growth factor-I receptor, is effective for Ewing sarcoma

المؤلفون: Daisuke Sawa, Hiroshi Moritake, Naoki Sameshima, Yusuke Saito, Ai Yamada, Mariko Kinoshita, Sachiyo Kamimura, Takao Konomoto, Hiroyuki Nunoi

المصدر: Cancer Medicine
Cancer Medicine, Vol 8, Iss 18, Pp 7809-7821 (2019)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cell cycle checkpoint, medicine.medical_treatment, Morpholines, Apoptosis, Sarcoma, Ewing, lcsh:RC254-282, Metastasis, Receptor, IGF Type 1, Focal adhesion, 03 medical and health sciences, Mice, 0302 clinical medicine, Cell Line, Tumor, medicine, Animals, Humans, metastasis, Radiology, Nuclear Medicine and imaging, Phosphorylation, Receptor, Protein kinase B, Protein Kinase Inhibitors, insulin‐like growth factor‐I receptor, Neoplasm Staging, Original Research, Cancer Biology, Dose-Response Relationship, Drug, Chemistry, Growth factor, TAE226, focal adhesion kinase, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Xenograft Model Antitumor Assays, Disease Models, Animal, 030104 developmental biology, Oncology, Metastatic Ewing Sarcoma, Tyrosine kinase 2, 030220 oncology & carcinogenesis, Focal Adhesion Protein-Tyrosine Kinases, Cancer research, Biomarkers, Ewing sarcoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86637986da7ed0d8281a70b8f7da8e4cTest
https://pubmed.ncbi.nlm.nih.gov/31692287Test

5

The putative role of insulin-like growth factor (IGF)-binding protein 5 independent of IGF in the maintenance of pulpal homeostasis in mice

المؤلفون: Kotaro Saito, Hayato Ohshima

المصدر: Regenerative Therapy
Regenerative Therapy, Vol 11, Iss, Pp 217-224 (2019)

مصطلحات موضوعية: 0301 basic medicine, Mice (Transgenic), IGF, insulin-like growth factor, medicine.medical_treatment, Biomedical Engineering, Apoptosis, In situ hybridization, Stem cells, PDLSCs, periodontal ligament stem cells, Biology, RT-PCR, reverse transcriptase-polymerase chain reaction, Biomaterials, DAB, diaminobenzidine, 03 medical and health sciences, 0302 clinical medicine, stomatognathic system, Dental pulp stem cells, medicine, IGFBP5, insulin-like growth factor binding protein 5, MAS, Matsunami adhesive silane, lcsh:QH573-671, IGF-IR, insulin-like growth factor I receptor, GFP, green fluorescent protein, lcsh:R5-920, Transplantation, TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling, lcsh:Cytology, Growth factor, Bone Marrow Stem Cell, H2B, histone 2B, Nestin, Cell biology, ANOVA, one-way analysis of variance, Dental pulp, stomatognathic diseases, 030104 developmental biology, DPSC, dental pulp stem cell, H&E, hematoxylin and eosin, Pulp (tooth), Original Article, Stem cell, LRC, label-retaining cell, lcsh:Medicine (General), 030217 neurology & neurosurgery, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8a7c6fe32aa97d4853b225f52ee7f1Test
https://pubmed.ncbi.nlm.nih.gov/31516919Test

6

The insulin-like growth factor-I receptor stimulating activity (IRSA) in health and disease

المؤلفون: Aimee J. Varewijck, Joseph A M J L Janssen, Michael P. Brugts

المساهمون: Internal Medicine

المصدر: Growth Hormone and IGF Research, 48-49, 16-28. Elsevier Ltd.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8fe57d416156063e23801e7678e0faTest
https://pure.eur.nl/en/publications/2110c387-62d7-447f-b7f5-fe810cb3c276Test

7

Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR

المؤلفون: Makoto Nakakido, Kouhei Tsumoto, Hirofumi Kosuge, Tetsuya Fukuda, Yasuhiko Bando, Satoru Nagatoishi, Shin-ichi Ohnuma

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: rsp75NTR, recombinant, soluble p75NTR, Proteomics, 0301 basic medicine, PRELP, proline and arginine-rich end leucine-rich repeat protein, Cellular homeostasis, growth factor receptor, IGFs, insulin-like growth factors, Cell morphology, Biochemistry, Carcinoma, Non-Small-Cell Lung, membrane protein, NF-κB, nuclear factor-kappa B, small leucine-rich proteoglycan (SLRP), Extracellular Matrix Proteins, DDM, n-dodecyl-β-D-maltoside, ESI, electrospray ionization, Chemistry, PRELP, IGFI-R, insulin-like growth factor I receptor, KD, dissociation constant, Recombinant Proteins, Cell biology, Gene Expression Regulation, Neoplastic, LRR, leucine-rich repeat, coimmunoprecipitation, Signal transduction, surface plasmon resonance (SPR), Research Article, rsIGFI-R, recombinant, soluble IGFI-R, P3, passage 3, NGF, nerve growth factor, SLRPs, small leucine-rich repeat proteoglycans, SPR, surface plasmon resonance, Nerve Tissue Proteins, Receptors, Nerve Growth Factor, Leucine-rich repeat, p75NTR, low-affinity nerve growth factor receptor p75NTR, Protein–protein interaction, 03 medical and health sciences, Growth factor receptor, TGF-β, transforming growth factor-β, Humans, RNA, Messenger, mAb, monoclonal antibody, Molecular Biology, GO, gene ontology, Glycoproteins, P1, passage 1, CoIP-MS, coimmunoprecipitation coupled with mass spectrometry, 030102 biochemistry & molecular biology, LRP1, low-density lipoprotein receptor-related protein 1, Cell Biology, protein–protein interaction, P2, passage 2, 030104 developmental biology, Membrane protein, A549 Cells, rPRELP, recombinant PRELP

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eb22586618166899a1725ed5c2b5fdTest
https://doi.org/10.1016/j.jbc.2021.100278Test

8

Combined and individual tumor-specific expression of insulin-like growth factor-I receptor, insulin receptor and phospho-insulin-like growth factor-I receptor/insulin receptor in primary breast cancer: Implications for prognosis in different treatment groups

المؤلفون: Helena Jernström, Sofie Björner, Andrea Markkula, Karin Jirström, Carsten Rose, Christian Ingvar, Signe Borgquist, Ann H. Rosendahl, Maria Simonsson

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Oncology, Time Factors, phospho-insulin-like growth factor-I receptor/insulin receptor, medicine.medical_treatment, Kaplan-Meier Estimate, Receptor, IGF Type 1, 0302 clinical medicine, Phosphorylation, insulin receptor, Receptor, education.field_of_study, Hematology, biology, Immunohistochemistry, Treatment Outcome, Receptors, Estrogen, 030220 oncology & carcinogenesis, Female, Research Paper, medicine.medical_specialty, Antineoplastic Agents, Hormonal, Population, insulin-like growth factor-I receptor, Breast Neoplasms, Lower risk, Disease-Free Survival, 03 medical and health sciences, Breast cancer, breast cancer, Antigens, CD, Predictive Value of Tests, Internal medicine, medicine, Biomarkers, Tumor, Humans, Neoplasm Invasiveness, education, Insulin-like growth factor 1 receptor, Proportional Hazards Models, Gynecology, Sweden, Radiotherapy, business.industry, Receptors, Somatomedin, medicine.disease, Receptor, Insulin, Radiation therapy, Insulin receptor, 030104 developmental biology, biology.protein, prognosis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cb67e95df2774440afdce449b19e89Test
https://pubmed.ncbi.nlm.nih.gov/28030849Test

9

Building the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy

المؤلفون: Terry J. Smith, Joseph A M J L Janssen

المساهمون: Internal Medicine

المصدر: Frontiers in Endocrinology
Frontiers in Endocrinology (Lausanne) (online), 7:167. Frontiers Media S.A.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420ca495296104c264e8dcc34ffa7591Test
http://europepmc.org/articles/PMC5206614Test

10

IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway

المؤلفون: Antonino Belfiore, Andrea Morrione, Roberta Matà, Marco Ragusa, Veronica Vella, Anna Rita Lo Presti, Roberta Malaguarnera, Maria Luisa Nicolosi, Daniela Sciortino, Marcello Maggiolini, Chiara Palladino

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Apoptosis, Immunoenzyme Techniques, Phosphatidylinositol 3-Kinases, Cell Movement, Tumor Cells, Cultured, DDR1, Insulin-Like Growth Factor I, Reverse Transcriptase Polymerase Chain Reaction, IGF-I, IGF-2, Gene Expression Regulation, Neoplastic, Oncology, Female, Collagen, Signal transduction, Signal Transduction, Research Paper, Transcriptional Activation, insulin, IGF-IR, Blotting, Western, insulin-like growth factor-I receptor, P70-S6 Kinase 1, Breast Neoplasms, Real-Time Polymerase Chain Reaction, 03 medical and health sciences, Breast cancer, breast cancer, Downregulation and upregulation, Discoidin Domain Receptor 1, Insulin-Like Growth Factor II, medicine, Humans, RNA, Messenger, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, business.industry, Gene Expression Profiling, Cancer, medicine.disease, IGF system, IGF-I, IGF system, insulin, IGF-2, MicroRNAs, 030104 developmental biology, Cancer research, business, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15da017b41d591d92c20b8defde7af95Test
https://pubmed.ncbi.nlm.nih.gov/26655502Test

تنقيح النتائج