نتائج البحث - "Diarmuid Smith"

1

Phase Ib Trial of Copanlisib, A Phosphoinositide-3 Kinase (PI3K) Inhibitor, with Trastuzumab in Advanced Pre-Treated HER2-Positive Breast Cancer 'PantHER'

المصدر: Cancers
Volume 13
Issue 6
Cancers, Vol 13, Iss 1225, p 1225 (2021)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Nausea, Phases of clinical research, lcsh:RC254-282, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Breast cancer, Trastuzumab, Internal medicine, medicine, breast neoplasms, Epidermal growth factor receptor, human, Adverse effect, skin and connective tissue diseases, neoplasms, Copanlisib, maximum tolerated dose, biology, business.industry, circulating tumour DNA, PIK3CA protein, phosphoinositide-3 kinase (PI3K), medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, trastuzumab, 030104 developmental biology, chemistry, Tolerability, 030220 oncology & carcinogenesis, biology.protein, medicine.symptom, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0deab293ab46fb93271be31f31b7ffdTest
http://europepmc.org/articles/PMC7999809Test

2

Activation of the non-canonical NF-κB/p52 pathway in vascular endothelial cells by RANKL elicits pro-calcific signalling in co-cultured smooth muscle cells

المؤلفون: Hannah Forde, Philip M. Cummins, Diarmuid Smith, Emma Harper, Keith D. Rochfort, Colin Davenport

المصدر: Cellular Signalling. 47:142-150

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92707446b6ebf70e1949f9f614ed8e0Test
https://doi.org/10.1016/j.cellsig.2018.04.004Test

3

RANKL Inhibits the Production of Osteoprotegerin from Smooth Muscle Cells under Basal Conditions and following Exposure to Cyclic Strain

المؤلفون: Colin Davenport, Keith D. Rochfort, Emma Harper, Diarmuid Smith, Philip M. Cummins, Hannah Forde

المصدر: Journal of Vascular Research. 55:111-123

مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, medicine.medical_specialty, Time Factors, Endothelium, Physiology, Myocytes, Smooth Muscle, Cell, Population, 030204 cardiovascular system & hematology, Mechanotransduction, Cellular, Article, Muscle, Smooth, Vascular, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Osteoprotegerin, Internal medicine, medicine, Humans, education, Receptor, Cells, Cultured, education.field_of_study, biology, Tumor Necrosis Factor-alpha, Chemistry, RANK Ligand, Glucose, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, RANKL, biology.protein, Tumor necrosis factor alpha, Stress, Mechanical, Cardiology and Cardiovascular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd8cc327ea1d7836316579739ffc99dTest
https://doi.org/10.1159/000486787Test

4

Growth hormone replacement may influence the biological action of thyroid hormone on liver and bone tissue

المؤلفون: David Halsall, Donal J. O’Gorman, Nigel Glynn, Paul Cook, Amar Agha, William Tormey, John H. McDermott, Christopher J. Thompson, Diarmuid Smith, Malachi J. McKenna, Gerard Boran

المصدر: Growth Hormone & IGF Research. :101393

مصطلحات موضوعية: Male, 0301 basic medicine, Endocrinology, Diabetes and Metabolism, Bone remodeling, 0302 clinical medicine, Endocrinology, Sex hormone-binding globulin, Sex Hormone-Binding Globulin, Prospective Studies, Insulin-Like Growth Factor I, Triiodothyronine, biology, Human Growth Hormone, Thyroid, Middle Aged, Hypothalamic–pituitary–thyroid axis, medicine.anatomical_structure, Liver, Osteocalcin, Bone Remodeling, Lipoproteins, HDL, Procollagen, Adenoma, Adult, medicine.medical_specialty, Hormone Replacement Therapy, 030209 endocrinology & metabolism, Bone and Bones, Collagen Type I, Hypopituitarism, Growth hormone deficiency, Young Adult, 03 medical and health sciences, Hypothyroidism, Internal medicine, medicine, Humans, Pituitary Neoplasms, Aged, business.industry, medicine.disease, Peptide Fragments, Thyroxine, 030104 developmental biology, Ferritins, biology.protein, Peptides, business, Lipoprotein(a), Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8759777064c495dcf89e8aacce48cea0Test
https://doi.org/10.1016/j.ghir.2021.101393Test

5

RANKL promotes osteoblastic activity in vascular smooth muscle cells by upregulating endothelial BMP-2 release

المؤلفون: Hannah Forde, Colin Davenport, Philip M. Cummins, Keith D. Rochfort, Ronan P. Murphy, Diarmuid Smith, Emma Harper

المصدر: The International Journal of Biochemistry & Cell Biology. 77:171-180

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7cdd47c74559ff99ba1958da45cdadTest
https://doi.org/10.1016/j.biocel.2016.06.009Test

6

RANKL treatment of vascular endothelial cells leading to paracrine pro-calcific signaling involves ROS production

المؤلفون: Philip M. Cummins, Keith D. Rochfort, Diarmuid Smith, Emma Harper

المصدر: Molecular and cellular biochemistry. 464(1-2)

مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, Adult, Male, Vascular smooth muscle, Clinical Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Paracrine signalling, 0302 clinical medicine, Paracrine Communication, Extracellular, medicine, Humans, Vascular Calcification, Molecular Biology, Aorta, chemistry.chemical_classification, Reactive oxygen species, biology, RANK Ligand, Endothelial Cells, Cell Biology, General Medicine, medicine.disease, Cell biology, Endothelial stem cell, 030104 developmental biology, chemistry, RANKL, 030220 oncology & carcinogenesis, Apocynin, cardiovascular system, biology.protein, Reactive Oxygen Species, Calcification, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e3d74d6b75f8aa60b0822549001165Test
https://pubmed.ncbi.nlm.nih.gov/31724123Test

7

Vascular calcification in type-2 diabetes and cardiovascular disease: Integrative roles for OPG, RANKL and TRAIL

المؤلفون: Hannah Forde, Colin Davenport, Emma Harper, Diarmuid Smith, Keith D. Rochfort, Philip M. Cummins

المصدر: Vascular Pharmacology. 82:30-40

مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, Physiology, Osteoclasts, Disease, 030204 cardiovascular system & hematology, Bioinformatics, Bone remodeling, TNF-Related Apoptosis-Inducing Ligand, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Osteoprotegerin, Osteogenesis, Animals, Humans, Medicine, Vascular Calcification, Receptor, Pharmacology, Osteoblasts, biology, business.industry, RANK Ligand, Cardiovascular Agents, NF-κB, Arteries, Atherosclerosis, Plaque, Atherosclerotic, 030104 developmental biology, Diabetes Mellitus, Type 2, chemistry, RANKL, Cardiovascular agent, Immunology, biology.protein, Molecular Medicine, business, Diabetic Angiopathies, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a9419fc3c02bbb21f80a619e23d50dTest
https://doi.org/10.1016/j.vph.2016.02.003Test

8

The beneficial pleiotropic effects of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) within the vasculature: A review of the evidence

المؤلفون: Colin Davenport, Robert G. Wallace, Philip M. Cummins, Emma Harper, Hannah Forde, Keith D. Rochfort, Ronan P. Murphy, Diarmuid Smith

المصدر: Atherosclerosis. 247

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a3f5b7a63e87a0ed8ddd6e82a992f2Test
https://pubmed.ncbi.nlm.nih.gov/26878368Test

9

TRAIL attenuates RANKL-mediated osteoblastic signalling in vascular cell mono-culture and co-culture models

المؤلفون: Hannah Forde, Emma Harper, Philip M. Cummins, Colin Davenport, Diarmuid Smith, Keith D. Rochfort

المصدر: PLoS ONE, Vol 12, Iss 11, p e0188192 (2017)
PLoS ONE

مصطلحات موضوعية: Male, 0301 basic medicine, Physiology, Cell, Bone Morphogenetic Protein 2, lcsh:Medicine, Alizarin Staining, Smooth Muscle Cells, 030204 cardiovascular system & hematology, Biochemistry, Epithelium, TNF-Related Apoptosis-Inducing Ligand, Endocrinology, 0302 clinical medicine, Cell Signaling, Animal Cells, Medicine and Health Sciences, Group-Specific Staining, Enzyme-Linked Immunoassays, lcsh:Science, Receptor, Cells, Cultured, Staining, Multidisciplinary, biology, Chemistry, Messenger RNA, Cell Differentiation, Osteoblast Differentiation, Cell biology, Nucleic acids, RUNX2, medicine.anatomical_structure, RANKL, Paracrine Signaling, Cellular Types, Anatomy, Signal Transduction, Research Article, Adult, musculoskeletal diseases, Endothelium, Muscle Tissue, Enzyme-Linked Immunosorbent Assay, Real-Time Polymerase Chain Reaction, Research and Analysis Methods, Models, Biological, Calcification, Young Adult, 03 medical and health sciences, Paracrine signalling, Osteoprotegerin, medicine, Humans, Immunoassays, Muscle Cells, Osteoblasts, Endocrine Physiology, RANK Ligand, lcsh:R, Biology and Life Sciences, Endothelial Cells, Epithelial Cells, Cell Biology, Coculture Techniques, Vasoprotective, Biological Tissue, 030104 developmental biology, Specimen Preparation and Treatment, Immunologic Techniques, biology.protein, RNA, lcsh:Q, Endothelium, Vascular, Physiological Processes, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908d19174354dbc92c318a22495ad987Test
https://doi.org/10.1371/journal.pone.0188192Test

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