المؤلفون: Anne T. Nies, Elke Schaeffeler, Kathrin Klein, Kathleen M. Giacomini, Michel Eichelbaum, Matthias Schwab, Ute Hofmann, Claudia Neul, Stefan Winter

المصدر: British Journal of Pharmacology. 178:1459-1474

مصطلحات موضوعية: 0301 basic medicine, CYP2D6, SLC47A1, Organic Cation Transport Proteins, Pharmacology, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cations, medicine, Humans, Organic cation transport proteins, biology, Chemistry, Sparteine, Organic Cation Transporter 2, Cytochrome P450, Phenotype, 030104 developmental biology, Cytochrome P-450 CYP2D6, Pharmaceutical Preparations, Debrisoquine, Perhexiline, biology.protein, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3555d075053f2fad1daf3c8541155Test
https://doi.org/10.1111/bph.15370Test

المؤلفون: Shiran Barber-Zucker, Fraser MacMillan, Afonso Froes, Sofiya Kolusheva, Jenny Hall, Raz Zarivach

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Crystallography, X-Ray, environment and public health, Biochemistry, structure-function, Cation Transport Proteins, chemistry.chemical_classification, 0303 health sciences, 030302 biochemistry & molecular biology, magnetotactic bacteria, Transmembrane domain, Metals, visual_art, Protein Structure and Folding, visual_art.visual_art_medium, Thermodynamics, Dimerization, Molecular Biophysics, Cation diffusion facilitator, Magnetotactic bacteria, metal selectivity, Calorimetry, Molecular Dynamics Simulation, Divalent, Metal, 03 medical and health sciences, metal ion-protein interaction, Transition metal, Bacterial Proteins, Protein Domains, Cations, Binding site, Magnetospirillum, Protein Structure, Quaternary, Molecular Biology, 030304 developmental biology, X-ray crystallography, Manganese, Binding Sites, 030102 biochemistry & molecular biology, metalloprotein, Cell Biology, electron paramagnetic resonance (EPR), 030104 developmental biology, Spectrometry, Fluorescence, chemistry, Cytoplasm, Biophysics, cation diffusion facilitator, CTD, Cation transport

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24002b89c4dd1d1c967e3de3817febdTest
http://europepmc.org/articles/PMC7864060Test

المؤلفون: Monica Bhanot, Elysa M. Wolf, Matthew A. Cottam, Nathan C. Winn, Alyssa H. Hasty

المصدر: Am J Physiol Endocrinol Metab

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Myeloid, Bioenergetics, Physiology, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Ferroportin, Adipose tissue, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Physiology (medical), Internal medicine, medicine, Animals, Insulin, Macrophage, Myeloid Cells, Cation Transport Proteins, Membrane Glycoproteins, biology, Macrophages, Receptors, Interleukin-1, Metabolism, medicine.disease, Mitochondria, Mice, Inbred C57BL, Glucose, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, biology.protein, Female, Energy Metabolism, 030217 neurology & neurosurgery, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8371afcfed30983d72490e1d328ec441Test
https://doi.org/10.1152/ajpendo.00116.2021Test

المؤلفون: Kristin E. Sandness, Steven H. Zeisel, Michael K. Georgieff, Judith K. Eckerle, Jeffrey R. Wozniak, Susan M. Smith, Christopher J. Boys, Manjot S Virdee

المصدر: Am J Clin Nutr

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Genotype, Organic Cation Transport Proteins, Population, Fetal alcohol syndrome, MTHFD1, Administration, Oral, Medicine (miscellaneous), Single-nucleotide polymorphism, Polymorphism, Single Nucleotide, Choline, 03 medical and health sciences, chemistry.chemical_compound, Cognition, 0302 clinical medicine, Antigens, CD, Internal medicine, Genetic model, medicine, Humans, education, Retrospective Studies, education.field_of_study, Nutrition and Dietetics, biology, business.industry, medicine.disease, Choline transporter, Original Research Communications, 030104 developmental biology, Gene Expression Regulation, chemistry, Fetal Alcohol Spectrum Disorders, Child, Preschool, Methylenetetrahydrofolate reductase, Dietary Supplements, biology.protein, Female, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c1b1ee44a5770640264d7ec0826bc4Test
https://doi.org/10.1093/ajcn/nqab081Test

المؤلفون: Lucas D. Ward, Ho-Chou Tu, Chelsea B. Quenneville, Shira Tsour, Alexander O. Flynn-Carroll, Margaret M. Parker, Aimee M. Deaton, Patrick A. J. Haslett, Luca A. Lotta, Niek Verweij, Manuel A. R. Ferreira, Regeneron Genetics Center, Geisinger-Regeneron DiscovEHR Collaboration, Aris Baras, Gregory Hinkle, Paul Nioi

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Cirrhosis, Genetic Linkage, General Physics and Astronomy, Genome-wide association study, Disease, Gastroenterology, Genome-wide association studies, Liver disease, 0302 clinical medicine, fluids and secretions, polycyclic compounds, Homeostasis, Cation Transport Proteins, Multidisciplinary, Bile duct, virus diseases, Alanine Transaminase, medicine.anatomical_structure, Phenotype, Hematocrit, Liver, medicine.medical_specialty, Heterozygote, Science, digestive system, General Biochemistry, Genetics and Molecular Biology, Article, Bile duct cancer, 03 medical and health sciences, Internal medicine, medicine, Humans, Aspartate Aminotransferases, Liver diseases, Genetic association, Manganese, business.industry, Genome, Human, Reproducibility of Results, Molecular Sequence Annotation, General Chemistry, medicine.disease, digestive system diseases, 030104 developmental biology, Iron-deficiency anemia, Gene Expression Regulation, Genetic Loci, Mutation, Hepatocytes, business, 030217 neurology & neurosurgery, Genome-Wide Association Study, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857f1ef5401527f6e9fe5885b8dac97dTest
https://doaj.org/article/f13505aebcc04860b9176de8ff12e468Test

المؤلفون: Swati Betharia, Rajitha Gadde

المصدر: Archives of Toxicology. 95:2643-2657

مصطلحات موضوعية: 0301 basic medicine, Antioxidant, Health, Toxicology and Mutagenesis, medicine.medical_treatment, 010501 environmental sciences, Pharmacology, Toxicology, medicine.disease_cause, 01 natural sciences, Neuroprotection, 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Benzene Derivatives, Organometallic Compounds, medicine, Humans, Sulfhydryl Compounds, Cation Transport Proteins, Chelating Agents, 0105 earth and related environmental sciences, Cell Death, General Medicine, Glutathione, Neuroprotective Agents, 030104 developmental biology, chemistry, Apoptosis, Dimercaptosuccinic acid, Lead acetate, Neuroinflammatory Diseases, Toxicity, Glioblastoma, Succimer, Oxidative stress, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323dcfa0f4e5af518d391c04fc8e4899Test
https://doi.org/10.1007/s00204-021-03103-2Test

المؤلفون: Elizabeth M. Parsons, Daniel D. Chung, Fengling Hu, Claire Castellano, Avery E. Tucker, Christopher T. DaVeiga, Emily Y. Park, Jingwen Zhang, Jennifer Gallegoe Iraheta, Rong Huang, Olena K. Vatamaniuk, Ju-Chen Chia, Jeeyon Jeong, Madeline Clyne, Angie Kim, Leah J. Kim, Kaitlyn M. Tsuyuki

المصدر: Plant J

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Chloroplasts, Iron, Mutant, Ferroportin, Arabidopsis, Plant Science, Biology, Mitochondrion, Plant Roots, 01 natural sciences, Article, 03 medical and health sciences, Gene Expression Regulation, Plant, Yeasts, Organelle, Genetics, medicine, Homeostasis, Amino Acid Sequence, Plastid, Cation Transport Proteins, Conserved Sequence, Arabidopsis Proteins, Chemistry, Wild type, food and beverages, Cell Biology, Iron deficiency, Plants, Genetically Modified, medicine.disease, biology.organism_classification, Mitochondria, Cell biology, Chloroplast, 030104 developmental biology, Mutation, biology.protein, 010606 plant biology & botany

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33aa76e2f923cc3827d386b910c5451Test
https://doi.org/10.1111/tpj.15286Test

المؤلفون: Christopher J. Law, Edel M. Hyland, Veronika Tóth, Pragya Sharma

المصدر: Malaria Journal, Vol 20, Iss 1, Pp 1-14 (2021)
Malaria Journal
Sharma, P, Tóth, V, Hyland, E M & Law, C J 2021, ' Characterization of the substrate binding site of an iron detoxifying membrane transporter from Plasmodium falciparum ', Malaria Journal, vol. 20, 295 . https://doi.org/10.1186/s12936-021-03827-7Test

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Vacuolar iron storage, Iron, Cytotoxicity, Saccharomyces cerevisiae, Plasmodium falciparum, RC955-962, Protozoan Proteins, Metal Binding Site, Infectious and parasitic diseases, RC109-216, 01 natural sciences, Ferrous, Comparative protein modelling, Integral membrane protein, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Protein-fragment complementation assay, Sequence Analysis, Protein, Iron homeostasis, Arctic medicine. Tropical medicine, Homology modeling, Binding site, Transition metal cations, Cation Transport Proteins, chemistry.chemical_classification, Membrane transporter, Binding Sites, biology, Chemistry, Research, Biological Transport, biology.organism_classification, Amino acid, 030104 developmental biology, Infectious Diseases, Biochemistry, Substrate binding, Parasitology, Sequence Alignment, 010606 plant biology & botany

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e5e0181ecb3b64d664ce64eb481b15Test
https://doaj.org/article/030af108791f4b79a84ceeed3c85cf4bTest

المؤلفون: Hiroaki Miki, Nobuhiko Yamamoto, Yosuke Funato, Daisuke Yamazaki, Daisuke Okuzaki

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Physiology, Receptor expression, General Physics and Astronomy, Blood Pressure, 030204 cardiovascular system & hematology, Kidney, Mice, Transient receptor potential channel, 0302 clinical medicine, Renin, Homeostasis, Magnesium, Kidney Tubules, Distal, Cation Transport Proteins, Oligonucleotide Array Sequence Analysis, Multidisciplinary, Chemistry, Adrenergic beta-Agonists, Circadian Rhythm, Up-Regulation, medicine.anatomical_structure, Hypertension, Female, RNA Interference, Cell biology, medicine.medical_specialty, Science, Down-Regulation, TRPM Cation Channels, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, Internal medicine, TRPM6, Renin–angiotensin system, medicine, Animals, Secretion, Distal convoluted tubule, Circadian rhythm, Isoproterenol, General Chemistry, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Blood pressure, Gene Expression Regulation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0eb862fe37003dec4b7a4753f2d4688Test
https://doaj.org/article/19ab4e3777194204aa8e0dcab04a04d6Test

المؤلفون: Guangxiong Chen, Yijie Xie

المصدر: Biochemical and Biophysical Research Communications. 557:213-220

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Cell Survival, Iron, Ferroportin, Biophysics, Saponin, Antineoplastic Agents, Diosgenin, Phenylenediamines, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Malondialdehyde, Antineoplastic Combined Chemotherapy Protocols, medicine, Ferroptosis, Humans, Viability assay, RNA, Small Interfering, Cation Transport Proteins, Melanoma, Molecular Biology, Benzophenanthridines, chemistry.chemical_classification, Cyclohexylamines, Cell Death, biology, Transferrin, Drug Synergism, Cell Biology, medicine.disease, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Reactive Oxygen Species, Intracellular

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9507a74d1391aed5bb1291264388b5dTest
https://doi.org/10.1016/j.bbrc.2021.04.024Test