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المؤلفون: Chitra Subramanian, Robert L. Matts, Brian S. J. Blagg, Anuj Khandelwal, Weiya Liu, Jeffery M. Holzbeierlein, Junpeng Deng, Mark S. Cohen, Victor W. Day, Sanket J. Mishra, Caitlin N. Kent, Maurie Balch, Shuxia Peng
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Gene isoform, Science, Drug Evaluation, Preclinical, General Physics and Astronomy, Antineoplastic Agents, Article, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, 03 medical and health sciences, Cell Line, Tumor, Heat shock protein, polycyclic compounds, medicine, Humans, Protein Isoforms, Structure–activity relationship, HSP90 Heat-Shock Proteins, Heat shock, lcsh:Science, Multidisciplinary, biology, Chemistry, HEK 293 cells, Cancer, Hydrogen Bonding, General Chemistry, medicine.disease, Hsp90, 3. Good health, Cell biology, HEK293 Cells, 030104 developmental biology, Drug Design, biology.protein, Protein folding, lcsh:Q
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca0d3fd460c06cb7b268c988c06edc1Test
http://link.springer.com/article/10.1038/s41467-017-02013-1Test -
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المؤلفون: Daniel T. Gewirth, Nanette L.S. Que, Adam S. Duerfeldt, Brian S. J. Blagg, Jinbo Zhao, Caitlin N. Kent, Vincent M. Crowley
المصدر: Journal of medicinal chemistry. 61(7)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Stereochemistry, Substituent, Molecular Conformation, Crystallography, X-Ray, Insert (molecular biology), Article, 03 medical and health sciences, Residue (chemistry), chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Adenosine Triphosphate, Dogs, Drug Discovery, Imidazole, Animals, Humans, HSP70 Heat-Shock Proteins, HSP90 Heat-Shock Proteins, biology, Chemistry, Membrane Proteins, Ligand (biochemistry), Hsp90, 030104 developmental biology, Cytoplasm, 030220 oncology & carcinogenesis, Drug Design, biology.protein, Molecular Medicine, Structure based, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccca754a8ee05065988cd16059cab867Test
https://pubmed.ncbi.nlm.nih.gov/29528635Test -
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المؤلفون: Caitlin N. Kent, I. K. Guttilla Reed
المصدر: Clinicaltranslational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 18(11)
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pathology, medicine.medical_specialty, Epithelial-Mesenchymal Transition, Biology, Metastasis, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Downregulation and upregulation, microRNA, medicine, Animals, Humans, Epithelial–mesenchymal transition, PI3K/AKT/mTOR pathway, Phosphoinositide 3-kinase, Endometrial cancer, General Medicine, medicine.disease, Endometrial Neoplasms, MicroRNAs, 030104 developmental biology, Oncology, Receptors, Estrogen, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Estrogen receptor alpha, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7972b3419cf290e94db35fa8e1af362cTest
https://pubmed.ncbi.nlm.nih.gov/26856598Test