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المؤلفون: Lena Voith von Voithenberg, Christopher Lux, Roland Stübe, Ji Young Park, Katrin Philippar, Youngsook Lee
المصدر: Frontiers in Plant Science, Vol 10 (2019)
Frontiers in Plant Scienceمصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, iron transport, ATP-binding cassette transporter, Plant Science, lcsh:Plant culture, 01 natural sciences, 03 medical and health sciences, chloroplast, Arabidopsis, Organelle, Arabidopsis thaliana, lcsh:SB1-1110, inner envelope membrane, Original Research, biology, Endosymbiosis, Chemistry, food and beverages, Prokaryote, energy-coupling factor transporter, biology.organism_classification, Cell biology, Chloroplast, 030104 developmental biology, metal homeostasis, ABC transporter, Biogenesis, 010606 plant biology & botany
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dff69d00d3ec3283157af7c24e9b045Test
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المؤلفون: Jun Li, Wenjing Qi, Wenbao Zhang, Tian Wang, Liping Duan, Yingfang Yu, Xiumin Han, Jia-Xu Chen, Lei Duan, Weisi Wang, Xueting Zheng, Shi-Zhu Li
المصدر: BMC Genomics, Vol 22, Iss 1, Pp 1-9 (2021)
BMC Genomicsمصطلحات موضوعية: 0301 basic medicine, Candidate gene, Spliceosome, endocrine system, 030231 tropical medicine, ATP-binding cassette transporter, Biology, QH426-470, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Echinococcosis, Heat shock protein, parasitic diseases, Genetics, Animals, Naphthyridines, KEGG, Echinococcus granulosus, Gene, Gene Expression Profiling, RNA sequencing, biology.organism_classification, Molecular biology, MAPK, 030104 developmental biology, Pharmaceutical Preparations, pyronaridine, ABC transporter, Protoscoleces, TP248.13-248.65, Research Article, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adf38c2376ea626f2c20c0778e7ce06Test
https://doaj.org/article/7a0dcad7cfea40569994c3734bd30615Test -
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المؤلفون: Annette Demmer, Hubert Thole, Manfred Raida, Burkhard Tümmler
المصدر: FEBS Open Bio, Vol 11, Iss 4, Pp 1084-1092 (2021)
FEBS Open Bioمصطلحات موضوعية: 0301 basic medicine, Edman sequencing, Protein Conformation, Lysine, Hamster, CHO Cells, anthracycline, General Biochemistry, Genetics and Molecular Biology, Iodine Radioisotopes, Structure-Activity Relationship, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, multidrug resistance, Cricetinae, P‐glycoprotein, Animals, Humans, Protein Interaction Domains and Motifs, ATP Binding Cassette Transporter, Subfamily B, Member 1, Binding site, lcsh:QH301-705.5, Research Articles, P-glycoprotein, Binding Sites, Membrane Glycoproteins, Edman degradation, biology, Photoaffinity labeling, Chemistry, Daunorubicin, drug‐binding site, Transmembrane protein, Transmembrane domain, 030104 developmental biology, Biochemistry, lcsh:Biology (General), 030220 oncology & carcinogenesis, biology.protein, ABC transporter, Peptides, Research Article, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2055486f6d55e1da7a4a56e9078189Test
https://doaj.org/article/c2b81dd83c9042d1b7692f7ae5d4f30bTest -
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المؤلفون: Yufei Chen, Huirong Chen, Shuangfei Li, Xuewei Yang, Liao Ouyang, Zhangli Hu, Madiha Zaynab
المصدر: Saudi Journal of Biological Sciences, Vol 28, Iss 3, Pp 1900-1912 (2021)
مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Genetics, biology, Biofilm, Motility, ATP-binding cassette transporter, Chemotaxis, Growth, biology.organism_classification, 01 natural sciences, Genome, Quorum sensing, 03 medical and health sciences, 030104 developmental biology, lcsh:Biology (General), ABC transporter, Biofilm formation, General Agricultural and Biological Sciences, lcsh:QH301-705.5, Gene, Bacteria, 010606 plant biology & botany
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2963945e3852d98180a2004ea4ba33eTest
https://doi.org/10.1016/j.sjbs.2020.12.041Test -
5Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein
المؤلفون: Sabrina Lusvarghi, Andaleeb Sajid, Eduardo E. Chufan, Biebele Abel, Stewart R. Durell, Megumi Murakami, Suresh V. Ambudkar, Michael M Gottesman
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: 0301 basic medicine, drug transport, Insecta, Mutant, mechanism, ATP-binding cassette transporter, P-glycoprotein, Biochemistry, Cell Line, Substrate Specificity, Cell membrane, 03 medical and health sciences, 0302 clinical medicine, multidrug resistance, ATP hydrolysis, Cell Line, Tumor, medicine, Animals, Humans, Rhodamine 123, ATP Binding Cassette Transporter, Subfamily B, Member 1, Binding Sites, Multidisciplinary, biology, Chemistry, Biological Transport, Transporter, Biological Sciences, Drug Resistance, Multiple, Cell biology, Molecular Docking Simulation, Transmembrane domain, 030104 developmental biology, medicine.anatomical_structure, Amino Acid Substitution, Pharmaceutical Preparations, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, biology.protein, ATP-Binding Cassette Transporters, ABC transporter, Efflux, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803755c3b785af07ef4d895aca61b154Test
https://doi.org/10.1073/pnas.2016270117Test -
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المصدر: Archives of Toxicology
مصطلحات موضوعية: 0301 basic medicine, Health, Toxicology and Mutagenesis, Receptors, Cytoplasmic and Nuclear, Cytochrome P450, ATP-binding cassette transporter, Toxicology, Substrate Specificity, chemistry.chemical_compound, 0302 clinical medicine, Cytochrome P-450 Enzyme System, Nuclear receptors, Constitutive androstane receptor, Receptor, Biotransformation, chemistry.chemical_classification, Pregnane X receptor, biology, Pregnane X Receptor, General Medicine, Isoenzymes, Liver, Pharmaceutical Preparations, Biochemistry, ABC transporter, Humanized mouse models, TXP, Azole fungicides, Cell Line, Xenobiotics, 03 medical and health sciences, Species Specificity, Animals, Humans, SLC transporter, Rats, Wistar, Constitutive Androstane Receptor, Membrane Transport Proteins, Biological Transport, Xenobiotic metabolism, Mice, Inbred C57BL, 030104 developmental biology, Enzyme, chemistry, Hepatocytes, biology.protein, Xenobiotic, 030217 neurology & neurosurgery, Drug metabolism, Toxicokinetics and Metabolism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d68922b9a83d8d78bd807b423907f1Test
https://doi.org/10.1007/s00204-020-02939-4Test -
7Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1
المؤلفون: Kaspar P. Locher, Julia Kowal, Kamil Nosol, Ksenija Romane, Rossitza N. Irobalieva, Amer Alam, Naoya Fujita
المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 117 (42)مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Drug, ATP Binding Cassette Transporter, Subfamily B, Protein Conformation, medicine.drug_class, media_common.quotation_subject, Tariquidar, ATP-binding cassette transporter, Monoclonal antibody, 03 medical and health sciences, 0302 clinical medicine, Tetrahydroisoquinolines, medicine, Humans, Cell Proliferation, P-glycoprotein, Zosuquidar, media_common, Multidisciplinary, biology, Chemistry, ABC transporter, ABCB1, Single-particle cryoelectron, Microscopy, Structure, Cryoelectron Microscopy, Antibodies, Monoclonal, Biological Sciences, Antineoplastic Agents, Phytogenic, Drug Resistance, Multiple, 3. Good health, Multiple drug resistance, HEK293 Cells, 030104 developmental biology, Biochemistry, Vincristine, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Acridines, Protein Binding, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25948a209e76c1b2f0e3390e3ef6d594Test
https://doi.org/10.1073/pnas.2010264117Test -
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المصدر: Hepatology (Baltimore, Md.)
مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Cell type, Malabsorption, Genotype, Myosin Type V, CHILDREN, Disease, Concise Reviews, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Malabsorption Syndromes, Cholestasis, Mucolipidoses, Internal medicine, Myosin, medicine, FAILURE, Humans, Intestinal Mucosa, Gamma-glutamyltransferase, Enterohepatic circulation, RAB11A, BILE-ACIDS, Microvilli, Myosin Heavy Chains, Hepatology, biology, Concise Review, business.industry, MYO5B MUTATIONS, ABC TRANSPORTER, MICROVILLUS INCLUSION DISEASE, gamma-Glutamyltransferase, medicine.disease, GENE, respiratory tract diseases, VB, Diarrhea, 030104 developmental biology, Liver, Mutation, biology.protein, 030211 gastroenterology & hepatology, medicine.symptom, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a49b362a3c82f65f030779c1748cab7Test
https://doi.org/10.1002/hep.31430Test -
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المؤلفون: Hélène Baubichon-Cortay, Ruttiros Khonkarn, Alexis Moreno, Luciano Saso, Sara Ranjbar, Omidreza Firuzi, Ramin Miri, Mehdi Khoshneviszadeh, Najmeh Edraki, Pierre Falson
المساهمون: Microbiologie moléculaire et biochimie structurale / Molecular Microbiology and Structural Biochemistry (MMSB), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Institut de biologie et chimie des protéines [Lyon] (IBCP), Department of Physiology and Pharmacology 'Vittorio Erspamer', Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome]
المصدر: Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology, Elsevier, 2019, 362, pp.136-149. ⟨10.1016/j.taap.2018.10.025⟩مصطلحات موضوعية: verapamil, Abcg2, aromatic compound, multidrug resistance-associated protein 1, Drug Resistance, ATP-binding cassette transporter, IC50, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, MES-SA/Dx5 cell line, Toxicology, 5-oxo-hexahydroquinoline, Rhodamine 123, 0302 clinical medicine, Antibiotics, 2 pyridyl alkyl carboxylic acid, 5 oxo hexahydroquinoline derivative, ABC transporter, ABC transporter subfamily B, antineoplastic agent, breast cancer resistance protein, calcein, carboxylic acid derivative, chlorine, doxorubicin, glutathione, mitoxantrone, multidrug resistance associated protein 1, pyridin 2 yethyl 2 methyl 4 ( 4 methoxyphenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylethyl 2 methyl 4 ( 2,3 dichlorophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylethyl 2 methyl 4 ( 2,4 dichlorophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylethyl 2 methyl 4 ( 4 chlorophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylethyl 2 methyl 4 ( 4 nitrophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylethyl 2 methyl 4 phenyl 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylpropyl 2 methyl 4 ( 2,3 dichlorophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylpropyl 2 methyl 4 ( 3 chlorophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylpropyl 2 methyl 4 ( 3 fluorophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylpropyl 2 methyl 4 ( 3 nitrophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylpropyl 2 methyl 4 ( 4 chlorophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridin 2 ylpropyl 2 methyl 4 ( 4 nitrophenyl) 5 oxo 1,4,5,6,7,8 hexahydroquinoline 3 carboxylic acid, pyridine derivative, quinoline derivative, rhodamine 123, unclassified drug, ABCG2 protein, human, antineoplastic antibiotic, multidrug resistance associated protein, tumor protein, Article, cancer cell, cancer cell line, controlled study, cytotoxicity, drug accumulation, drug design, drug synthesis, flow cytometry, gene overexpression, growth inhibition, human, human cell, in vitro study, MES-SA cell line, multidrug resistance, sarcoma cell line, substitution reaction, uterus sarcoma, animal, cell line, drug effect, drug resistance, hamster, metabolism, neoplasm, physiology, Animals, Antibiotics, Antineoplastic, ATP Binding Cassette Transporter, Subfamily B, Member 1, ATP Binding Cassette Transporter, Subfamily G, Member 2, Cell Line, Cricetinae, Doxorubicin, Drug Resistance, Multiple, Drug Resistance, Neoplasm, Glutathione, Humans, Multidrug Resistance-Associated Proteins, Neoplasm Proteins, Neoplasms, Quinolines, ABCB1, ABCC1, ABCG2, Calcein AM, Mitoxantrone, pyridin 2 ylethyl 2 methyl 4 phenyl 5 oxo 1, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Antineoplastic, 3. Good health, pyridin 2 ylpropyl 2 methyl 4 ( 2, 030220 oncology & carcinogenesis, pyridin 2 ylpropyl 2 methyl 4 ( 3 fluorophenyl) 5 oxo 1, Efflux, Multiple, 3 dichlorophenyl) 5 oxo 1, Member 2, Member 1, Article, 03 medical and health sciences, tumor protein, pyridin 2 ylethyl 2 methyl 4 ( 4 nitrophenyl) 5 oxo 1, Pharmacology, ABCG2 protein, medicine.disease, 030104 developmental biology, 4 dichlorophenyl) 5 oxo 1, chemistry, Cancer cell, pyridin 2 ylpropyl 2 methyl 4 ( 3 nitrophenyl) 5 oxo 1, 0301 basic medicine, Subfamily G, chemistry.chemical_compound, pyridin 2 ylethyl 2 methyl 4 ( 2, pyridin 2 ylpropyl 2 methyl 4 ( 4 chlorophenyl) 5 oxo 1, biology, pyridin 2 ylpropyl 2 methyl 4 ( 4 nitrophenyl) 5 oxo 1, pyridin 2 ylpropyl 2 methyl 4 ( 3 chlorophenyl) 5 oxo 1, Subfamily B, ATP Binding Cassette Transporter, [SDV.CAN]Life Sciences [q-bio]/Cancer, medicine, Animals, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], 8 hexahydroquinoline 3 carboxylic acid, pyridin 2 yethyl 2 methyl 4 ( 4 methoxyphenyl) 5 oxo 1, Cancer, pyridin 2 ylethyl 2 methyl 4 ( 4 chlorophenyl) 5 oxo 1, Multiple drug resistance, physiology, biology.protein, Cancer research, Neoplasm
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8162307a6064ea46b515f5a5ae0a26Test
https://doi.org/10.1016/j.taap.2018.10.025Test -
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المؤلفون: Kentaro Shimizu, Takatoshi Arakawa, Kiyohiko Igarashi, Shinya Fushinobu, Naohisa Sugimoto, Masayuki Miyake, Michiko Shimokawa, Tohru Terada, Kiyotaka Fujita
المصدر: Miyake, M, Terada, T, Shimokawa, M, Sugimoto, N, Arakawa, T, Shimizu, K, Igarashi, K, Fujita, K & Fushinobu, S 2020, ' Structural analysis of β-L-arabinobiose-binding protein in the metabolic pathway of hydroxyproline-rich glycoproteins in Bifidobacterium longum ', FEBS Journal, vol. 287, no. 23, pp. 5114-5129 . https://doi.org/10.1111/febs.15315Test
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Bifidobacterium longum, Protein Conformation, substrate-binding protein, ATP-binding cassette transporter, Crystallography, X-Ray, Disaccharides, Biochemistry, Substrate Specificity, 03 medical and health sciences, 0302 clinical medicine, Bacterial Proteins, human gut bacterium, Humans, Molecular Biology, Glycoproteins, chemistry.chemical_classification, biology, Binding protein, Isothermal titration calorimetry, Cell Biology, computer.file_format, biology.organism_classification, Protein Data Bank, isothermal titration calorimetry, Hydroxyproline, Metabolic pathway, molecular dynamics simulation, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, ABC transporter, Carrier Proteins, Glycoprotein, computer, Metabolic Networks and Pathways, Bacteria
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e401c778585eebd4a61738a5eb70a9Test
https://doi.org/10.1111/febs.15315Test