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المؤلفون: Manoj Kumar Panigrahi, Smreti Vasudevan, Ullas Batra, Sanjeev Sharma, Anurag Mehta, Moushumi Suryavanshi, Mumtaz Saifi
المصدر: Applied Cancer Research, Vol 40, Iss 1, Pp 1-12 (2020)
مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, medicine.disease_cause, lcsh:RC254-282, DNA sequencing, Tyrosine-kinase inhibitor, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Compound mutations, Lung cancer, Gene, High-throughput sequencing, business.industry, Driver mutations, General Medicine, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Clinical trial, 030104 developmental biology, Fusion transcript, 030220 oncology & carcinogenesis, KRAS, business, Single-gene assay
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8c5360a27951783b5a285642e3f492Test
http://link.springer.com/article/10.1186/s41241-020-00089-8Test -
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المؤلفون: Yael P. Mosse, Courtney M. Smith, Krishna Suresh, Ravi Radhakrishnan, Abigail A Lemmon, Keshav Patil, Jin H. Park, Mark A. Lemmon, Earl Joseph Jordan
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, alpha-Helical, driver mutations, Disease, Computational biology, Biology, Molecular Dynamics Simulation, medicine.disease_cause, kinase activation, Machine Learning, 03 medical and health sciences, 0302 clinical medicine, medicine, Anaplastic lymphoma kinase, Humans, Anaplastic Lymphoma Kinase, chemistry.chemical_classification, Mutation, Multidisciplinary, Kinase, Cancer, Biological Sciences, medicine.disease, molecular dynamics, Amino acid, focus formation assay, Enzyme Activation, Biophysics and Computational Biology, 030104 developmental biology, chemistry, Protein kinase domain, 030220 oncology & carcinogenesis, Target protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9199b12102cdd0e542ec239a708e35afTest
http://europepmc.org/articles/PMC7958353Test -
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المؤلفون: Clare Fiala, Eleftherios P. Diamandis
المصدر: BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-9 (2020)مصطلحات موضوعية: 0301 basic medicine, Adult, DNA Mutational Analysis, Normal tissue, lcsh:Medicine, Context (language use), Disease, Review, medicine.disease_cause, Normal tissues, 03 medical and health sciences, Young Adult, 0302 clinical medicine, medicine, Humans, Gene, Aged, Mutation, Circulating tumor DNA, business.industry, lcsh:R, Driver mutations, Cancer, General Medicine, Middle Aged, medicine.disease, 030104 developmental biology, The Hallmarks of Cancer, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, business, Mutations, Passenger mutations
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e5e26cfddf582179c94bbbc1336f44Test
http://europepmc.org/articles/PMC7594459Test -
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المؤلفون: Irene Vanni, Enrica Teresa Tanda, Bruna Dalmasso, Lorenza Pastorino, Virginia Andreotti, William Bruno, Andrea Boutros, Francesco Spagnolo, Paola Ghiorzo
المصدر: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 7 (2020)مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Mutation rate, driver mutations, medicine.medical_treatment, Disease, Review, Biology, medicine.disease_cause, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, medicine, melanoma, Molecular Biosciences, Gene, Molecular Biology, lcsh:QH301-705.5, non-BRAF mutation, Mutation, Genetic heterogeneity, Melanoma, medicine.disease, targeted therapy, 030104 developmental biology, lcsh:Biology (General), 030220 oncology & carcinogenesis, Cancer research, genetic, heterogeneity, WES, WGS
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963d6500283ca19c51304fc876c8998cTest
http://europepmc.org/articles/PMC7396525Test -
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المؤلفون: Phyu P. Aung, Jonathan L. Curry, Dzifa Y. Duose, Sri Krishna C. Arudra, Leomar Y. Ballester, Doina Ivan, Haider A. Mejbel, Carlos A. Torres-Cabala, Victor G. Prieto, Dinesh Pradhan, Michael T. Tetzlaff, Raja Luthra, Priyadharsini Nagarajan
المصدر: Cancers, Vol 11, Iss 11, p 1714 (2019)
Cancers
Volume 11
Issue 11مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pathology, medicine.medical_specialty, driver mutations, Biology, medicine.disease_cause, lcsh:RC254-282, DNA sequencing, Article, 03 medical and health sciences, 0302 clinical medicine, tumor heterogeneity, medicine, melanoma, Neoplasm, Gene, Mutation, histophenotypic heterogeneity, Genetic heterogeneity, Melanoma, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 030104 developmental biology, Oncology, Tumor morphology, 030220 oncology & carcinogenesis, Immunohistochemistry, next-generation sequencing
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9656d65ef57d54663485da9aff6da058Test
https://www.mdpi.com/2072-6694/11/11/1714Test -
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المؤلفون: Helano C. Freitas, Giovana Tardin Torrezan, Isabela Werneck da Cunha, Mariana Petaccia Macedo, Vanessa Karen de Sá, Marcelo Corassa, Elisa Napolitano e Ferreira, Augusto Obuti Saito, Graziela Zibetti Dal Molin, Vladmir C. Cordeiro de Lima, Dirce Maria Carraro
المصدر: Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)مصطلحات موضوعية: 0301 basic medicine, Oncology, Neuroblastoma RAS viral oncogene homolog, Cancer Research, medicine.medical_specialty, Mutation rate, driver mutations, EGFR, medicine.disease_cause, lcsh:RC254-282, 03 medical and health sciences, symbols.namesake, Exon, 0302 clinical medicine, Internal medicine, medicine, Gene, Original Research, Sanger sequencing, molecular testing, business.industry, medicine.disease, Molecular diagnostics, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lung adenocarcinoma, targeted therapies, respiratory tract diseases, 030104 developmental biology, 030220 oncology & carcinogenesis, symbols, Adenocarcinoma, KRAS, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3599700fd86ea87693eb4838bea3dfb1Test
https://pubmed.ncbi.nlm.nih.gov/32714871Test -
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المؤلفون: Karl Hartmann, Bernd Klosterhalfen, Felipe Crespo, Nikolaos Mitsimponas, Maria Mitsogianni, Aristoteles Giagounidis, Sabine Haase
المصدر: Case Reports in Oncology
Case Reports in Oncology, Vol 11, Iss 1, Pp 109-113 (2018)مصطلحات موضوعية: 0301 basic medicine, Lung adenocarcinoma, Case Report, medicine.disease_cause, lcsh:RC254-282, Hairy cell leukemia, 03 medical and health sciences, 0302 clinical medicine, Non-small cell lung cancer, medicine, BRAF-V600E mutation, Lung cancer, neoplasms, Mutation, Lung, business.industry, Driver mutations, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, digestive system diseases, BRAF V600E, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Concomitant, Cancer research, Adenocarcinoma, Non small cell, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4338c075b7febf42a5f0db89f807420fTest
http://europepmc.org/articles/PMC5869534Test -
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المؤلفون: Barani Kumar Rajendran, Chu-Xia Deng
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, driver mutations, Breast Neoplasms, Review, Tumor initiation, genetic mutations, medicine.disease_cause, Bioinformatics, Metastasis, 03 medical and health sciences, breast cancer, Breast cancer, medicine, Humans, breast cancer driver genes, Mutation, business.industry, cancer drivers, Computational Biology, Cancer, medicine.disease, Pathway analysis, 030104 developmental biology, Oncology, Female, business, Carcinogenesis, human activities, Human breast
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739c95d73610ff3d603576e70d0e73fdTest
https://doi.org/10.18632/oncotarget.17225Test -
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المؤلفون: Gianluca Ascolani, Pietro Liò
المساهمون: Apollo - University of Cambridge Repository, Lio, Pietro [0000-0002-0540-5053]
المصدر: BMC Medical Genomics
BMC Medical Genomics, Vol 12, Iss S6, Pp 1-19 (2019)مصطلحات موضوعية: 0301 basic medicine, lcsh:Internal medicine, lcsh:QH426-470, Cell, Bone Neoplasms, Breast Neoplasms, Computational biology, Biology, medicine.disease_cause, Models, Biological, Metastasis, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, Genetics, medicine, Humans, Non-commuting operators, lcsh:RC31-1245, Genetics (clinical), Mutation, Subordinated processes, Research, Metabolic mutations, Mutation order, Driver mutations, Cancer, medicine.disease, Human genetics, lcsh:Genetics, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer cell, Neoplastic Stem Cells, DNA microarray
وصف الملف: application/pdf; text/xml
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bba6249b94b96028bf1b686ea78aeeTest
https://doi.org/10.1186/s12920-019-0541-4Test -
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المؤلفون: Yijiu Ren, Shujun Huang, Chenyang Dai, Dong Xie, Larry Zheng, Huikang Xie, Hui Zheng, Yunlang She, Fangyu Zhou, Yue Wang, Pengpeng Li, Ke Fei, Gening Jiang, Yang Zhang, Bo Su, E. Alejandro Sweet-Cordero, Nhan Le Tran, Yanan Yang, Jai N. Patel, Christian Rolfo, Gaetano Rocco, Andrés Felipe Cardona, Alessandro Tuzi, Matteo B. Suter, Ping Yang, Wayne Xu, Chang Chen
المصدر: Frontiers in Oncology, Vol 9 (2019)
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, driver mutations, Somatic cell, Oncology and Carcinogenesis, Biology, medicine.disease_cause, lcsh:RC254-282, Germline, 03 medical and health sciences, ground-glass nodule, 0302 clinical medicine, Germline mutation, medicine, Copy-number variation, whole-exome sequencing, Indel, Exome sequencing, Genetics, copy number variation, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lung cancer, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, KRAS, Carcinogenesis
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac04901cff495004843788e2346fac2Test