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المؤلفون: Marcel Leist, Anna Bal-Price, Florianne Monnet-Tschudi, Andrea Terron, Stefan Schildknecht, Susanne Hougaard Bennekou, Alicia Paini
المصدر: Archives of Toxicology
Arch Toxicolمصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Health, Toxicology and Mutagenesis, Substantia nigra, Regulatory decision-making, Disease, Review Article, Toxicology, Letter to the Editor, News and Views, Pesticide exposure, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Adverse outcome pathway, Parkinsonian Disorders, ddc:570, Rotenone, Adverse Outcome Pathway, medicine, Animals, Humans, Pesticides, Neuroinflammation, MPTP, Electron Transport Complex I, Adverse Outcome Pathways, business.industry, Dopaminergic, General Medicine, medicine.disease, Mitochondria, 3. Good health, 030104 developmental biology, Proteostasis, chemistry, Parkinson’s disease, Mitochondrial complex I inhibitor, business, Neuroscience, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7b4ab14e1e376848d5348bc563d1c8Test
http://europepmc.org/articles/PMC5773657Test -
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المؤلفون: M.E. (Bette) Meek, Anna Bal-Price
المصدر: Pharmacology & Therapeutics
مصطلحات موضوعية: 0301 basic medicine, KE, key event, OECD, Organisation for Economic Co-operation and Development, Disease, PD, Parkinson's disease, Toxicology, DNT, developmental neurotoxicity, AOP, adverse outcome pathway, Adverse Outcome Pathway, MPTP, 1-methyl-4-phenyl-3104 1,2,3,6-tetrahydropyridine, Pharmacology (medical), Mechanistic understanding, B/H, Bradford-Hill, HTT, high-throughput toxicity testing, CNS, Central nervous system, TFHA, Task Force for Hazard Assessment, Late stage, Neurodegenerative Diseases, Weight of evidence, ADME, absorption, distribution, metabolism and excretion, CI, complex I of mitochondrial chain, Mechanism (philosophy), Environmental Pollutants, Neurotoxicity Syndromes, WNT, Working Group of the National Coordinators for the Test Guidelines Programme, KER, key event relationship, Neurotoxicity Syndrome, Adverse outcomes, AO, adverse outcome, BDNF, brain derived neurotrophic factor, Receptors, N-Methyl-D-Aspartate, MIE, molecular initiating event, Article, Quantitation, Economic cooperation, 03 medical and health sciences, NT, neurotoxicity, Key event relationship, Toxicity Tests, medicine, Neurotoxicity, Animals, Humans, PBPK, physiologically based pharmacokinetic, WOE, weight of evidence, Key event, QSAR, quantitative structure activity relationship, Pharmacology, Adverse Outcome Pathways, AD, Alzheimer disease, business.industry, MOA, mode of action, AOP-KB, adverse outcome pathway knowledge base, medicine.disease, IATA, integrated approaches to testing and assessment, 030104 developmental biology, business, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0e7e3f2e48fbac9d167c3c1f6d69d2Test
https://pubmed.ncbi.nlm.nih.gov/28529068Test -
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المصدر: Neurochemistry international. 108
مصطلحات موضوعية: 0301 basic medicine, Cell type, Programmed cell death, Neurite, NF-E2-Related Factor 2, Neurogenesis, Induced Pluripotent Stem Cells, Biology, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Neural Stem Cells, Rotenone, medicine, Humans, Cells, Cultured, Neurons, Uncoupling Agents, Neurotoxicity, Cell Differentiation, Cell Biology, respiratory system, medicine.disease, Neural stem cell, 030104 developmental biology, medicine.anatomical_structure, nervous system, chemistry, Astrocytes, Signal transduction, Neuroscience, 030217 neurology & neurosurgery, Astrocyte
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf953dd9e2e6ec74a6026b37606a986Test
https://pubmed.ncbi.nlm.nih.gov/28627367Test -
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المؤلفون: David Canovas-Jorda, Dimitra Zagoura, Anna Bal-Price, Susanne Bremer-Hoffmann, Francesca Pistollato
المصدر: Neurochemistry international. 106
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Insecticides, NF-E2-Related Factor 2, Induced Pluripotent Stem Cells, Drug Evaluation, Preclinical, Biology, medicine.disease_cause, Neuroprotection, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Rotenone, medicine, Animals, Humans, Induced pluripotent stem cell, Cells, Cultured, Neurons, Nrf2 pathway, Neurotoxicity, Human induced pluripotent stem cells, Cell Biology, medicine.disease, KEAP1, Coculture Techniques, Cell biology, Rats, Oxidative Stress, 030104 developmental biology, P19 cell, chemistry, Female, Neuronal/glial cultures, Oxidative stress, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2299a7ddbb1954a2b7e6163124a54729Test
https://pubmed.ncbi.nlm.nih.gov/27615060Test -
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المؤلفون: Timothy J. Shafer, A. Vassallo, Sergio Martinoia, Tzutzuy Ramirez, Timo Weisschu, Enrico Defranchi, Maurice Whelan, Anna Bal-Price, Michela Chiappalone, Antonio Novellino, Andrew F.M. Johnstone, Robert Landsiedel, Ricardo De Camargos Lopes, Taina Palosaari, Bibiana Scelfo, Cina M. Mack
المصدر: Neurotoxicology. 60
مصطلحات موضوعية: 0301 basic medicine, Insecticides, Neurotoxins, Drug Evaluation, Preclinical, Pharmacology, Toxicology, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, 0302 clinical medicine, Extracellular, medicine, Animals, Cells, Cultured, Microelectrode array, Neurons, Neuroscience (all), Artificial neural network, Cross-laboratory comparison, Screening, General Neuroscience, Organophosphate, Neurotoxicity, Domoic acid, Multielectrode array, medicine.disease, Rats, 030104 developmental biology, Deltamethrin, chemistry, Microelectrodes, 030217 neurology & neurosurgery, Dimethyl phthalate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc2c5f764b7dccd2bc50c2aff3bb94cTest
https://pubmed.ncbi.nlm.nih.gov/27036093Test -
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المؤلفون: Pamela J. Lein, Marta Barenys, Magdalini Sachana, Sunjay Sethi, Timothy J. Shafer, Anna Bal-Price, Ellen Fritsche, M.E. (Bette) Meek, Kimberly P. Keil
المصدر: Bal-Price, Anna; Lein, Pamela J; Keil, Kimberly P; Sethi, Sunjay; Shafer, Timothy; Barenys, Marta; et al.(2017). Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity.. Neurotoxicology, 59, 240-255. doi: 10.1016/j.neuro.2016.05.010. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2b41z9w5Test
Neurotoxicology, vol 59مصطلحات موضوعية: 0301 basic medicine, Adverse outcome pathways, Neurotoxicity Syndrome, Neuroscience(all), Neurotoxins, Biology, Bioinformatics, Toxicology, Nervous System, Risk Assessment, Article, 03 medical and health sciences, Structure-Activity Relationship, Adverse Outcome Pathway, medicine, Neurotoxicity, Animals, Humans, Mode of action, Risk assessment, Event (computing), General Neuroscience, Stressor, Neurosciences, Pharmacology and Pharmaceutical Sciences, medicine.disease, 030104 developmental biology, Biological target, Neurological, Neurotoxicity Syndromes, Generic health relevance, Neuroscience, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ed292e45e26ec95dd68ea6f9a9fe88Test
