نتائج البحث - "Animal Experiment"

1

Molecular and behavioural abnormalities in the FUS-tg mice mimic frontotemporal lobar degeneration

المؤلفون: Diana Babaevskaya, Andrey Proshin, Igor Pomytkin, Margarita Oplatchikova, Tatyana Strekalova, Johannes P.J.M. de Munter, D. A. Pavlov, Allan V. Kalueff, Klaus-Peter Lesch, Ekaterina Lysikova, Anna Gorlova, Erik Ch. Wolters, Aleksei Umriukhin

المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience

المصدر: Journal of Cellular and Molecular Medicine, 24(17), 10251-10257. Wiley-Blackwell
Journal of Cellular and Molecular Medicine
J. Cell. Mol. Med.

مصطلحات موضوعية: Male, Pathology, amyotrophic lateral sclerosis, PROTEIN EXPRESSION, EXPERIMENTAL NEUROINFLAMMATION, REAL TIME POLYMERASE CHAIN REACTION, MOUSE, ANIMAL EXPERIMENT, stem cell therapy, FUS[1‐359]‐tg mice, Mice, 0302 clinical medicine, SUCROSE PREFERENCE TEST, CELECOXIB, BRAIN, MUTATION, FUS[1-359]-tg mice, Neurons, RNA BINDING PROTEIN FUS, Behavior, Animal, celecoxib, LOCOMOTION, Neurodegeneration, TRANSGENIC MOUSE, Brain, DEPRESSION, Riluzole, Spinal Cord, 030220 oncology & carcinogenesis, RNA ISOLATION, CALCIUM BINDING PROTEIN, DRUG EFFECT, medicine.medical_specialty, Short Communication, Short Communications, FUS PROTEIN, MOUSE, IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1, BEHAVIOR, ANIMAL, INTERLEUKIN-1BETA, NEUROINFLAMMATION, 03 medical and health sciences, TAIL SUSPENSION TEST, NONHUMAN, Social Behavior, ELEVATED PLUS MAZE TEST, INTERLEUKIN 1BETA, FRONTOTEMPORAL LOBAR DEGENERATION, Glycogen Synthase Kinase 3 beta, animal model, ANIMALS, ANIMAL, medicine.disease, FUS[1-359]-TG MICE, Molecular medicine, 030104 developmental biology, Mutation, HIPPOCAMPUS, emotionality and cognition, CYCLOOXYGENASE 1, HOME-CAGE ACTIVITY TEST, ABNORMAL BEHAVIOR, SPINAL CORD, GELATINASE B, CYCLOOXYGENASE 2, 0301 basic medicine, MATRIX METALLOPROTEINASES, NERVE CELL, Interleukin-1beta, Anti-Inflammatory Agents, Hippocampus, PREFRONTAL CORTEX, ANIMAL MODEL, UNCLASSIFIED DRUG, neuroinflammation, MARBLE BURYING TEST, ANXIETY, COGNITIVE DEFECT, TISSUE INHIBITOR OF METALLOPROTEINASE 1, PLASTICITY, Amyotrophic lateral sclerosis, NEURONS, MOLECULAR MARKER, Frontotemporal lobar degeneration, STEM CELL, riluzole, Muscle atrophy, GENOTYPE, ANTIINFLAMMATORY ACTIVITY, frontotemporal lobar degeneration, BIOLOGICAL MARKER, GLYCOGEN SYNTHASE KINASE 3BETA, Molecular Medicine, AMYOTROPHIC LATERAL SCLEROSIS, RNA-BINDING PROTEIN FUS, medicine.symptom, ANTIINFLAMMATORY AGENT, medicine.drug, STEM CELL THERAPY, GLYCOGEN SYNTHASE KINASE 3 BETA, CAGE TEST, METABOLISM, ADULT, INFLAMMATION, WESTERN BLOTTING, ANIMAL TISSUE, GENE MUTATION, OPEN FIELD TEST, EMOTION, medicine, Animals, RESIDENT-INTRUDER TEST, ARTICLE, NERVE DEGENERATION, Neuroinflammation, Inflammation, MALE, TUMOR NECROSIS FACTOR, INTRACEREBROVENTRICULAR DRUG ADMINISTRATION, business.industry, SOCIAL BEHAVIOR, ANTI-INFLAMMATORY AGENTS, Cell Biology, FRONTOTEMPORAL DEMENTIA, ANIMAL BEHAVIOR, EMOTIONALITY AND COGNITION, CONTROLLED STUDY, MICE, GLYCOGEN SYNTHASE KINASE 3ALPHA, Cyclooxygenase 2, RILUZOLE, COGNITION, RNA-Binding Protein FUS, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06827f1ecd2f754817e6fe6568533e8Test
https://cris.maastrichtuniversity.nl/en/publications/0162d1c6-abc0-4610-83d0-566d46a45289Test

2

Stem cell therapy for Alzheimer's disease

المؤلفون: Lan Zhao, Lin-Po Yang, Xin-Yu Liu

المصدر: World Journal of Stem Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85009517117d15cf3bca1e2c7364d117Test
https://doi.org/10.4252/wjsc.v12.i8.787Test

3

Effect of High Fructose Corn Sirup on Pancreatic Ductal Adenocarcinoma Induced by Dimethyl Benzantracene (DMBA) in Rats

المؤلفون: Ömer Tarım, Ilker Ercan, Ekrem Kaya, Mustafa Barış Akgül, Senem Suna, Halit Ziya Dündar, Gürsel Sönmez, Turkkan Evrensel, Emre Sarandol, Bige Incedayi, Canan Ece Tamer, Sevda Inan, Deniz Bagdas, Ömer Utku Çopur, Deniz Sigirli, Gulsah Ozcan-Sinir

المساهمون: Bursa Uludağ Üniversitesi/Ziraat Fakültesi/Gıda Mühendisliği Bölümü., Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Patoloji Anabilim Dalı., Bursa Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Onkoloji Anabilim Dalı., Bursa Uludağ Üniversitesi/Tıp Fakültesi/Cerrahi Anabilim Dalı., Bursa Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı., Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Endokrinolojisi Anabilim Dalı., Sinir-Özcan, Gülşah, Suna, Senem, Tamer, Canan Ece, Sönmez, Gürsel, Evrensel, Türkkan, Kaya, Ekrem, Sarandöl, Emre, Dündar, Halit Ziya, Tarım, Ömer Faruk, Ercan, İlker, Sığırlı, Deniz, İncedayı, Bige, Çopur, Ömer Utku, AAG-8277-2021, ABE-1716-2020, AAQ-8178-2020, AAJ-1027-2021, AAG-7319-2021, AAG-8503-2021, AAG-8336-2021, AAA-7472-2021, ABF-2367-2020

المصدر: Nutrition and Cancer. 73:339-349

مصطلحات موضوعية: Male, 0301 basic medicine, Sucrose, Cancer Research, Intraepithelial neoplasia, Carcinoma, pancreatic ductal, Rats, sprague-dawley, Carcinogenesis, Glucose blood level, Medicine (miscellaneous), DMBA, Animal tissue, chemistry.chemical_compound, 0302 clinical medicine, Food intake, Glycemic load, Cancer morphology, Nutrition and Dietetics, digestive, oral, and skin physiology, food and beverages, Pancreatic Neoplasms, Pancreas Adenocarcinoma, Chronic Pancreatitis, Nectar, 7,12 dimethylbenz[a]anthracene, Sprague dawley rat, Fructose intake, Chow diet, Oncology, 030220 oncology & carcinogenesis, Pancreas tumor, Normal dietary consumption, Autopsy, Pancreas adenocarcinoma, medicine.medical_specialty, Pancreatic neoplasms, 9,10-Dimethyl-1,2-benzanthracene, Histopathology, Fructose, Tumor differentiation, Body-weight, Zea mays, Pooled analysis, Article, 03 medical and health sciences, Internal medicine, Pancreatic cancer, Sham procedure, medicine, Carcinoma, Animals, High fructose corn syrup, Animal model, Clinical evaluation, Obesity, Animal experiment, Sugar, Cancer-risk, Nutrition & dietetics, 030109 nutrition & dietetics, Corn syrup, Animal, High-fructose corn syrup, Insulin-resistance, Body weight, Nonhuman, Peach, medicine.disease, Rats, Maize, Glucose, Endocrinology, chemistry, High fructose, Rat, Data analysis software, Comparative study, Pancreas carcinoma, Controlled study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad5d3ee9b82ac47639219a1f626c9afTest
https://doi.org/10.1080/01635581.2020.1770811Test

4

Neuro-Cells therapy improves motor outcomes and suppresses inflammation during experimental syndrome of amyotrophic lateral sclerosis in mice

المؤلفون: Klaus-Peter Lesch, Boris W. Kramer, Ekaterina Veniaminova, Anna Gorlova, Andrei Svistunov, Tatyana Strekalova, D. A. Pavlov, Alexei Liundup, Igor Shafarevich, Erik Ch. Wolters, Aleksei Umriukhin, Allan V. Kalueff, Johannes P.J.M. de Munter

المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience, Promovendi MHN, Kindergeneeskunde, MUMC+: MA Medische Staf Kindergeneeskunde (9)

المصدر: CNS Neuroscience & Therapeutics, 26(5), 504-517. Wiley
CNS Neuroscience & Therapeutics
CNS Neuroscience and Therapeutics

مصطلحات موضوعية: Male, medicine.medical_treatment, MOUSE, PHENOTYPE, ANIMAL EXPERIMENT, stem cell therapy, INJURED SPINAL-CORD, Mice, 0302 clinical medicine, HUMAN CELL, Pharmacology (medical), CELECOXIB, Cells, Cultured, Motor Neurons, FUSED IN SARCOMA (FUS) PROTEIN, fused in sarcoma (FUS) protein, MARROW STROMAL CELLS, FLUID INTAKE, TRANSGENIC MOUSE, Hematopoietic Stem Cell Transplantation, HUMAN, SUPEROXIDE DISMUTASE-1 (SOD-1) G93A MICE, Stem-cell therapy, MOUSE MODEL, Riluzole, Motor Skills Disorders, Psychiatry and Mental health, EXPERIMENTAL NEUROLOGIC DISEASE, Editorial, IONIZED CALCIUM BINDING ADAPTER MOLECULE 1, TRIAL, BODY WEIGHT GAIN, DRUG EFFECT, medicine.medical_specialty, microglia activation, COPPER ZINC SUPEROXIDE DISMUTASE, 03 medical and health sciences, DISEASE EXACERBATION, NERVE CELL DEGENERATION, Physiology (medical), NONHUMAN, mouse, Pharmacology, MUTATIONS, Amyotrophic Lateral Sclerosis, medicine.disease, 030104 developmental biology, Endocrinology, PILOT STUDY, 030217 neurology & neurosurgery, 0301 basic medicine, amyotrophic lateral sclerosis (ALS), STRESS, HEMATOPOIETIC STEM CELL, Anti-Inflammatory Agents, ANIMAL MODEL, UNCLASSIFIED DRUG, glycogen-synthase kinase-3 ss (GSK-3 ss), GLYCOGEN-SYNTHASE KINASE-3ß (GSK-3ß), Amyotrophic lateral sclerosis, MSOD1 MOUSE, CELL MARKER, MOTOR PERFORMANCE, STEM CELL TRANSPLANTATION, Muscle atrophy, MICROGLIA ACTIVATION, Treatment Outcome, superoxide dismutase-1 (SOD-1) G93A mice, AMYOTROPHIC LATERAL SCLEROSIS (ALS), GLYCOGEN SYNTHASE KINASE 3BETA, AMYOTROPHIC LATERAL SCLEROSIS, Inflammation Mediators, Stem cell, medicine.symptom, medicine.drug, STEM CELL THERAPY, Mice, Transgenic, Inflammation, MESENCHYMAL STEM CELL, MESENCHYMAL STEM-CELLS, INFLAMMATION, ANIMAL TISSUE, Internal medicine, GENE MUTATION, medicine, Animals, ARTICLE, MUSCLE ATROPHY, Injections, Intraventricular, MALE, Superoxide Dismutase, business.industry, TRANSPLANTATION, CONTROLLED STUDY, Transplantation, RILUZOLE, Celecoxib, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c69fa0680dc92ef5fa087eff247a317Test
https://cris.maastrichtuniversity.nl/en/publications/2dada5b0-a0d3-43b8-a6ad-5c8eedfc634dTest

5

Pregabalin Ameliorates Lipopolysaccharide-Induced Pancreatic Inflammation in Aged Rats

المؤلفون: Ozlem Ozmen, Senay Topsakal

المصدر: Endocrine, Metabolic & Immune Disorders - Drug Targets. 19:1141-1147

مصطلحات موضوعية: Lipopolysaccharides, 0301 basic medicine, Lipopolysaccharide, cell infiltration, Endocrinology, Diabetes and Metabolism, pancreatitis, Anti-Inflammatory Agents, Pregabalin, Nitric Oxide Synthase Type II, Wistar rat, immune response, granulocyte colony stimulating factor, sepsis, Pathogenesis, chemistry.chemical_compound, 0302 clinical medicine, biochemical analysis, caspase 3, Nos2 protein, rat, Granulocyte Colony-Stimulating Factor, Pathology, Immunology and Allergy, rat, animal, pancreas, glucose, biology, Caspase 3, lipopolysaccharide, drug effect, single drug dose, Immunohistochemistry, Nitric oxide synthase, female, medicine.anatomical_structure, 030220 oncology & carcinogenesis, histopathology, Female, lipids (amino acids, peptides, and proteins), Inflammation Mediators, Pancreas, antiinflammatory agent, signal transduction, Signal Transduction, medicine.drug, amylase, medicine.medical_specialty, autacoid, cell protection, Casp3 protein, rat, animal experiment, interleukin 6, Granulocyte, Il6 protein, rat, Article, leucocyte infiltration, animal tissue, Sepsis, 03 medical and health sciences, Animals, Anti-Inflammatory Agents/*pharmacology, Caspase 3/metabolism, Cytoprotection, Disease Models, Animal, Granulocyte Colony-Stimulating Factor/metabolism, Inflammation Mediators/metabolism, Interleukin-6/metabolism, Nitric Oxide Synthase Type II/metabolism, Pancreas/*drug effects/metabolism/pathology, Pancreatitis/blood/chemically induced/pathology/*prevention & control, Pregabalin/*pharmacology, Rats, Wistar, Serum Amyloid A Protein/metabolism, Signal Transdu, blood, Internal medicine, medicine, Endocrine system, controlled study, neutrophil chemotaxis, protein expression, Serum Amyloid A Protein, nonhuman, Interleukin-6, business.industry, animal model, disease model, aging, inducible nitric oxide synthase, serum amyloid A, triacylglycerol lipase, medicine.disease, 030104 developmental biology, Endocrinology, Pancreatitis, chemistry, biology.protein, business, metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f9114be52657faf470b2e0452280f8Test
https://doi.org/10.2174/1871530319666190306095532Test

6

Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism

المصدر: EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
EMBO Molecular Medicine 13 (2021), Nr. 4
EMBO Molecular Medicine
EMBO Mol. Med.:e12461 (2021)

مصطلحات موضوعية: 0301 basic medicine, pyrimidine, Medicine (General), pyrimidine derivative, cancer metabolism, CHOP, QH426-470, chemistry.chemical_compound, 0302 clinical medicine, cell stress, metabolic vulnerabilities, Neoplasms, Medicine, antineoplastic agent, Cancer, cancer cell, Cell Death, catabolism, Articles, integrated stress response, Drug repositioning, Paclitaxel, Pyrimidine metabolism, tricyclic antidepressants, Molecular Medicine, metabolome, Signal Transduction, organoid, animal experiment, Antineoplastic Agents, Article, 03 medical and health sciences, R5-920, male, pyrimidine synthesis, Chemical Biology, Metabolome, Genetics, Integrated stress response, Humans, controlled study, ddc:610, human, Cancer Metabolism, Integrated Stress Response, Metabolic Vulnerabilities, Pyrimidine Metabolism, Tricyclic Antidepressants, mouse, nonhuman, business.industry, animal model, human cell, niclosamide, growth arrest and DNA damage inducible protein 153, medicine.disease, pyrimidine metabolism, 030104 developmental biology, Pyrimidines, chemistry, Cancer cell, Cancer research, Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit, business, transcriptome, 030217 neurology & neurosurgery, neoplasm

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844403979915d09946eb8173a03d57e3Test
https://doaj.org/article/5b69fc35368c4378aea983eb723c06a2Test

7

Application of modified closed biopsy in rabbit model of VX2-transplanted bone tumor

المؤلفون: Hai Ying Cao, Jia Xing Lv, Ling Wei Kong, Yu Jin, Lei Peng Bai

المصدر: Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-8 (2021)
Journal of Orthopaedic Surgery and Research

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, lcsh:Diseases of the musculoskeletal system, CD34, Periosteal reaction, Gene Expression, Antigens, CD34, Bone Neoplasms, Enzyme-Linked Immunosorbent Assay, Elisa, Metastasis, law.invention, Intramedullary rod, Tumor infiltration, 03 medical and health sciences, 0302 clinical medicine, lcsh:Orthopedic surgery, law, Proliferating Cell Nuclear Antigen, Biopsy, Biomarkers, Tumor, Animals, Medicine, Orthopedics and Sports Medicine, Animal experiment, Tibia, Neoplasm Metastasis, Bone tumor, medicine.diagnostic_test, business.industry, Biopsy, Needle, Soft tissue, Closed biopsy, medicine.disease, Radiography, Disease Models, Animal, lcsh:RD701-811, 030104 developmental biology, 030220 oncology & carcinogenesis, Orthopedic surgery, Surgery, Rabbits, lcsh:RC925-935, Biopsy channel metastasis, business, Nuclear medicine, Neoplasm Transplantation, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df97fe17040ad3f38c54932914a108f1Test
https://doi.org/10.1186/s13018-021-02333-5Test

8

The Effect of Strontium Ranelate Gel on Bone Formation in Calvarial Critical Size Defects

المؤلفون: Sherine A. Nasry, Hani El Nahass, Nada Nour El Din

المصدر: Open Access Macedonian Journal of Medical Sciences
Open Access Macedonian Journal of Medical Sciences; Vol 5, No 7 (2017): Dec 15 (OAMJMS); 994-999
Open Access Macedonian Journal of Medical Sciences, Vol 5, Iss 7, Pp 994-999 (2017)
Open Access Macedonian Journal of Medical Sciences; Vol 5 No 7 (2017): Dec 15 (OAMJMS); 994-999

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8212c8686f84b831a2922b15eec6047dTest
https://doi.org/10.3889/oamjms.2017.164Test

9

The effects of type I collagen on bone defects and gene expression changes for osteogenesis: In a rat model

المؤلفون: Nilay Sen-Türk, Yavuz Dodurga, Ahmet Fahir Demirkan, Özgür Yiğiter, Ali Çağdaş Yörükoğlu

المصدر: Journal of Cellular Biochemistry. 120:11525-11530

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d33d5330a5f9b3cf387c99255ec22f5Test
https://doi.org/10.1002/jcb.28432Test

10

Recruitment of macrophages and bone marrow stem cells to regenerating liver promoted by sodium phthalhydrazide in mice

المؤلفون: Irina A. Kazakova, Boris G. Yushkov, Irina G. Danilova, Anna V. Belousova, Artem S. Minin, Musa T. Abidov

المصدر: Biomedicine and Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 110, Iss, Pp 594-601 (2019)

مصطلحات موضوعية: Male, BONE MARROW MACROPHAGES, Antioxidant, medicine.medical_treatment, Bone marrow macrophages, PROTEIN, MOUSE, PHENOTYPE, HEPATOPROTECTIVE PHARMACEUTICALS, ANIMAL EXPERIMENT, Antioxidants, Mice, 0302 clinical medicine, ANTIOXIDANT, PARTIAL HEPATECTOMY (PH), Macrophage, MONOCYTE, BONE MARROW STEM CELLS, Liver injury, Bone marrow stem cells, IMMUNOMODULATION, Bone Marrow Stem Cell, General Medicine, Liver regeneration, 030220 oncology & carcinogenesis, KI 67 ANTIGEN, DRUG EFFECT, RM1-950, ALBUMIN, 03 medical and health sciences, NONHUMAN, IMMUNOHISTOCHEMISTRY, Partial hepatectomy (PH), Pharmacology, Macrophages, ANIMALS, Albumin, Mesenchymal Stem Cells, LIVER CELL, ANIMAL, Hematopoietic Stem Cells, medicine.disease, RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASE C, 030104 developmental biology, CELL MIGRATION, Mice, Inbred CBA, Phthalazines, RAT, LIVER REGENERATION, PARTIAL HEPATECTOMY, MACROPHAGE, Liver recovery, Hepatoprotective pharmaceuticals, 0301 basic medicine, HEMATOPOIETIC STEM CELL, HYDRAZINES, ANIMAL MODEL, UNCLASSIFIED DRUG, ANTIOXIDANTS, MACROPHAGES, PRIORITY JOURNAL, STEM CELL TRANSPLANTATION, PHTHALAZINES, LIVER TISSUE, LIVER RECOVERY, PHTHALAZINE DERIVATIVE, MESENCHYMAL STEM CELLS, Hydrazines, medicine.anatomical_structure, LIVER INJURY, Stem cell, HYDRAZINE DERIVATIVE, CELL POLARITY, METABOLISM, MESENCHYMAL STEM CELL, RATS, 2 AMINO 1,2,3,4 TETRAHYDROPHTHALAZINE 1,4 DIONE SODIUM SALT DIHYDRATE, ANIMAL TISSUE, MICE, INBRED CBA, medicine, Animals, STEM CELL FACTOR RECEPTOR, ARTICLE, HEMATOPOIETIC STEM CELLS, PHYSIOLOGY, LIVER PROTECTION, CBA MOUSE, MALE, business.industry, Rats, CD172A ANTIGEN, CONTROLLED STUDY, MICE, ANIMAL CELL, CELL PROLIFERATION, Cancer research, SINGLE DRUG DOSE, Therapeutics. Pharmacology, Bone marrow, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62004ce2a8dde201baab9995b4a28de8Test
https://doi.org/10.1016/j.biopha.2018.07.086Test

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