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المؤلفون: Tamer Coskun, Claire H. Feetham, Giuseppe D'Agostino, Garron T. Dodd, Amy A. Worth, Frank Reimann, James D. Dunbar, Fiona M. Gribble, Simon M. Luckman, Paul J. Emmerson, Katie Tye, Emily C Beebe, Dana Sindelar, Jesline T. Alexander-Chacko, Rosemary Shoop
المساهمون: Worth, Amy A [0000-0003-2573-7140], Shoop, Rosemary [0000-0002-3617-4358], Luckman, Simon M [0000-0001-5318-5473], Apollo - University of Cambridge Repository
المصدر: Worth, A A, Shoop, R, Tye, K, Feetham, C H, D'Agostino, G, Dodd, G T, Reimann, F, Gribble, F M, Beebe, E C, Dunbar, J D, Alexander-Chacko, J T, Sindelar, D K, Coskun, T, Emmerson, P J & Luckman, S M 2020, ' The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling ', eLife, vol. 9, e55164, pp. 1-19 . https://doi.org/10.7554/eLife.55164Test
eLife, Vol 9 (2020)
eLifeمصطلحات موضوعية: 0301 basic medicine, Male, food intake, Lydia Becker Institute, medicine.medical_treatment, cisplatin, brainstem, neuroscience, Rats, Sprague-Dawley, Mice, Random Allocation, 0302 clinical medicine, rat, Biology (General), Receptor, Cholecystokinin, Neurons, education.field_of_study, GFRAL, General Neuroscience, Area postrema, General Medicine, Recombinant Proteins, Anorexia, Cytokine, Pica, Medicine, medicine.symptom, Signal transduction, Research Article, Signal Transduction, medicine.medical_specialty, Growth Differentiation Factor 15, QH301-705.5, Science, Population, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Internal medicine, ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation, medicine, Animals, education, mouse, General Immunology and Microbiology, CCK, Rats, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, GDF15, nervous system, Anorectic, 030217 neurology & neurosurgery, Brain Stem
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c36fee4c12ae9aa6d1944526e39affeTest
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المؤلفون: Patrick J. Antonellis, James W. Perfield, Brian A. Droz, Tamer Coskun, Richard Cosgrove, Tara E. Chouinard, Andrew C. Adams, Steven M. Bauer, Mark R. Wade, Libbey S. O’Farrell, Ricardo J. Samms, Joseph T. Brozinick
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 30, Iss, Pp 131-139 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, CYP7A1, Adipose tissue, Mice, Obese, FGF19, Mice, 0302 clinical medicine, Adipose Tissue, Brown, Brown adipose tissue, Uncoupling Protein 1, Mice, Knockout, Bile acid, Chemistry, Thermogenesis, Thermogenin, Mitochondria, medicine.anatomical_structure, medicine.medical_specialty, lcsh:Internal medicine, UCP1, medicine.drug_class, Adipose Tissue, White, 030209 endocrinology & metabolism, Cholesterol 7 alpha-hydroxylase, Brief Communication, Diet, High-Fat, Diabetes Mellitus, Experimental, Mitochondrial Proteins, 03 medical and health sciences, Internal medicine, medicine, Animals, Obesity, lcsh:RC31-1245, Molecular Biology, Lipogenesis, Body Weight, BAT, Lipid metabolism, Cell Biology, Lipid Metabolism, Fibroblast Growth Factors, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Metabolic, Insulin Resistance, Energy Metabolism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3a672ee97f46b2f383c07d191a28e6Test
https://pubmed.ncbi.nlm.nih.gov/31767164Test -
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المؤلفون: Qian Liu, Ruth E. Gimeno, Jason X. Tang, Gavin C. Barnard, Xilin Liu, Yong Du, Jorge Alsina-Fernandez, Paul J. Emmerson, Avinash Muppidi, Bei B Zhang, Richard Todd Pickard, Matthew J Hamang, Bei Shan, Tamer Coskun, Pamela Jean Mitchell, Malgorzata Donata Gonciarz, Kimberly K Ballman, John H. Sloan, Xinle Wu, Xudong Mao, Lisa A Foltz, Feng Wang, Dana Sindelar, Robert W. Siegel
المصدر: Nature Medicine. 23:1215-1219
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Glial Cell Line-Derived Neurotrophic Factor Receptors, Growth Differentiation Factor 15, Immunoblotting, Biology, Real-Time Polymerase Chain Reaction, General Biochemistry, Genetics and Molecular Biology, Rats, Sprague-Dawley, Eating, Mice, 03 medical and health sciences, Estrogen-related receptor alpha, 0302 clinical medicine, Internal medicine, Weight Loss, medicine, Animals, Humans, 5-HT5A receptor, Obesity, RNA, Messenger, Receptor, Mice, Knockout, Orphan receptor, Brain, General Medicine, Surface Plasmon Resonance, Flow Cytometry, Rats, Neuron-derived orphan receptor 1, Macaca fascicularis, HEK293 Cells, 030104 developmental biology, Endocrinology, Area Postrema, ROR1, Estrogen-related receptor gamma, GDF15, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502200f39c5bdc1b589339efb20908aTest
https://doi.org/10.1038/nm.4393Test -
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المؤلفون: Joseph T. Brozinick, Steve Bauer, Evan M Niemeier, Thais de Castro Barbosa, Alexander V. Chibalin, Jorge Alsina-Fernandez, Julie Massart, Håkan K. R. Karlsson, Tamer Coskun, Lili Guo, Elizabeth O'Farrell, Juleen R. Zierath, Andrew Ryan, Milena Schönke, Anna Krook, Melissa L. Borg, Rebecca R. Miles, Mark R. Wade
المصدر: Diabetes. 68(7)
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Blotting, Western, 030209 endocrinology & metabolism, 03 medical and health sciences, Gastrocnemius muscle, Mice, 0302 clinical medicine, Insulin resistance, Internal medicine, Internal Medicine, medicine, Myocyte, Animals, Humans, Phosphorylation, Muscle, Skeletal, Urocortins, Soleus muscle, biology, Chemistry, Insulin, Skeletal muscle, medicine.disease, Rats, Mice, Inbred C57BL, Insulin receptor, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Electroporation, Glucose, HEK293 Cells, biology.protein, Body Composition, Insulin Resistance, GLUT4, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cae7ff42babbca68b2c86cdd35ffd7Test
https://pubmed.ncbi.nlm.nih.gov/31010957Test -
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المؤلفون: Geerte Hoeke, Anne Reifel Miller, Patrick C.N. Rensen, Lea H. Dib, Bharat Shimpukade, Trond Ulven, Tamer Coskun, Anthony Okolo, Sander Kooijman, Maaike Schilperoort, Natarin Caengprasath, Mark Christian, Yi-Wah Chan, Aylin C. Hanyaloglu, Andrea D. van Dam, Sami Damak, Isabel M. Mol, Irina G. Shabalina
المساهمون: Biotechnology and Biological Sciences Research Council (BBSRC)
المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
EMBO Molecular Medicine, 10(3)
Schilperoort, M, van Dam, A D, Hoeke, G, Shabalina, I G, Okolo, A, Hanyaloglu, A C, Dib, L H, Mol, I M, Caengprasath, N, Chan, Y-W, Damak, S, Miller, A R, Coskun, T, Shimpukade, B, Ulven, T, Kooijman, S, Rensen, P C & Christian, M 2018, ' The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat ', EMBO Molecular Medicine, vol. 10, no. 3, e8047 . https://doi.org/10.15252/emmm.201708047Testمصطلحات موضوعية: 0301 basic medicine, Male, Medicine (General), Ca, GPR120, Adipocytes, White, Gene Expression Regulation/drug effects, Phenylpropionates/pharmacology, QH426-470, Mitochondrion, Receptors, G-Protein-Coupled, Oxygen Consumption/drug effects, Adipose Tissue, Brown, Receptors, G-Protein-Coupled/agonists, Brown adipose tissue, lipid metabolism, Glucose/metabolism, Adipose Tissue, Brown/drug effects, Research Articles, Uncoupling Protein 1, Adiposity, Phenylpropionates, Chemistry, Cell Differentiation, 11 Medical And Health Sciences, Lipids, Mitochondria/drug effects, mitochondria, Ca2+, medicine.anatomical_structure, Adipocytes, Brown, Molecular Medicine, Adipocytes, Brown/cytology, Mitochondrial fission, Oxidation-Reduction, Research Article, Agonist, medicine.medical_specialty, medicine.drug_class, Adipose Tissue, White, Cell Respiration, Adiposity/drug effects, Carbohydrate metabolism, Models, Biological, Adipocytes, White/cytology, 03 medical and health sciences, R5-920, Oxygen Consumption, Adipose Tissue, White/drug effects, Internal medicine, Cell Respiration/drug effects, Genetics, medicine, Animals, Body Weight/drug effects, Pharmacology & Drug Discovery, Biphenyl Compounds, Body Weight, Uncoupling Protein 1/metabolism, Lipid metabolism, brown adipose tissue, 06 Biological Sciences, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Metabolism, Glucose, Gene Expression Regulation, Cell Differentiation/drug effects, Biphenyl Compounds/pharmacology, Thermogenesis, RC
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e500a414f38fbfef93af89f8a97f0493Test
http://wrap.warwick.ac.uk/97936/1/GPR120-agonist-TUG-391-promotes-Christian-2018.pdfTest -
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المؤلفون: Richard G. Peterson, Karen M. Zimmerman, M. Dodson Michael, Bria L. Sneed, Paul J. Emmerson, Brian A. Droz, Charles V. Jackson, Tamer Coskun
المصدر: PLoS ONE, Vol 12, Iss 6, p e0179808 (2017)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Leptin, Blood Glucose, Male, Physiology, medicine.medical_treatment, Peptide Hormones, Type 2 diabetes, Biochemistry, Fats, Eating, Mice, 0302 clinical medicine, Endocrinology, Hyperinsulinemia, Medicine and Health Sciences, Medicine, Insulin, 2. Zero hunger, Multidisciplinary, Organic Compounds, Monosaccharides, Animal Models, Lipids, 3. Good health, Chemistry, Physiological Parameters, Experimental Organism Systems, Physical Sciences, medicine.symptom, Research Article, medicine.medical_specialty, Offspring, Science, Carbohydrates, 030209 endocrinology & metabolism, Mouse Models, Research and Analysis Methods, Diet, High-Fat, 03 medical and health sciences, Insulin resistance, Model Organisms, Diabetes mellitus, Internal medicine, Animals, Obesity, Pancreas, Nutrition, Diabetic Endocrinology, business.industry, Body Weight, Organic Chemistry, Chemical Compounds, Biology and Life Sciences, medicine.disease, Hormones, Diet, 030104 developmental biology, Glucose, Diabetes Mellitus, Type 2, business, Weight gain
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff96d25ea08c7654451bfe234ee4c5aTest
https://doaj.org/article/bb9f14c1cae741f99f99a57996878039Test -
7Short-term cooling increases serum triglycerides and small high-density lipoprotein levels in humans
المؤلفون: Geerte Hoeke, Tamer Coskun, Donna Lee M. Dinnes, Sabine S.C. Norkauer, Philipp Pagel, Jimmy F.P. Berbée, Laurent O. Martinez, Kimberly J. Nahon, Ingrid M. Jazet, Anne Reifel-Miller, Fred P.H.T.M. Romijn, Patrick C.N. Rensen, Maaike Kockx, Mariëtte R. Boon, Christa M. Cobbaert, Leontine E. H. Bakker, Diana Drettwan, Leonard Kritharides, Laeticia Lichtenstein
المصدر: Journal of Clinical Lipidology
Journal of Clinical Lipidology, 11(4), 920-928مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Very low-density lipoprotein, Time Factors, Endocrinology, Diabetes and Metabolism, Cold exposure, 030204 cardiovascular system & hematology, Brown adipose tissue, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, High-density lipoprotein, Internal medicine, Internal Medicine, medicine, Humans, Particle Size, Triglycerides, Intermediate-density lipoprotein, Nutrition and Dietetics, biology, Catabolism, Cholesterol, nutritional and metabolic diseases, Biological Transport, Healthy Volunteers, Cold Temperature, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, chemistry, Lipids and lipoprotein metabolism, ABCA1, biology.protein, lipids (amino acids, peptides, and proteins), Lipoproteins, HDL, Cardiology and Cardiovascular Medicine, ATP Binding Cassette Transporter 1, Lipoprotein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7f86946a712d14b2f96b5373313675Test
https://hdl.handle.net/1887/115000Test