المؤلفون: Julie Ducharme, Vanja Polic, Christopher J. Thibodeaux, Karine Auclair

المصدر: ACS Chemical Biology. 16:882-890

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Allosteric regulation, Hydrogen Deuterium Exchange-Mass Spectrometry, Plasma protein binding, Molecular Dynamics Simulation, Ligands, 01 natural sciences, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, Protein structure, Cytochrome P-450 CYP3A, Humans, Structure–activity relationship, Bioconjugation, 010405 organic chemistry, Ligand, Chemistry, Deuterium Exchange Measurement, General Medicine, Deuterium, Small molecule, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Biophysics, Molecular Medicine, Hydrogen–deuterium exchange, Allosteric Site, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0676cc08793fae1577d21f2c72cee82Test
https://doi.org/10.1021/acschembio.1c00084Test

المؤلفون: Huihao Zhou, Bernhard Kuhle, Jingjing Zhang, Zaneta Matuszek, Litao Sun, Rita Horvath, Paul Schimmel, David Blocquel, Tao Pan, Na Wei, Thomas Weber, Philippe Latour, Xiang-Lei Yang, Weiwei He, Patrick R. Griffin, Scott J. Novick

المساهمون: Sun, Litao [0000-0002-4192-5136], Kuhle, Bernhard [0000-0002-0501-1150], Novick, Scott [0000-0003-0213-3897], Matuszek, Zaneta [0000-0001-5627-0593], Zhou, Huihao [0000-0002-9675-5007], He, Weiwei [0000-0002-4432-6454], Zhang, Jingjing [0000-0002-6348-3877], Weber, Thomas [0000-0002-9519-2046], Horvath, Rita [0000-0002-9841-170X], Griffin, Patrick R [0000-0002-3404-690X], Yang, Xiang-Lei [0000-0003-2554-084X], Apollo - University of Cambridge Repository

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: 0301 basic medicine, Protein family, medicine.medical_treatment, Primary Cell Culture, Mutant, Aminoacylation, Charcot-Marie-Tooth disease, Crystallography, X-Ray, medicine.disease_cause, Biochemistry, neuropilin 1, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Scattering, Small Angle, Neuropilin 1, medicine, Humans, Lymphocytes, Receptor, Cells, Cultured, Genetics, Mutation, Multidisciplinary, Protease, Chemistry, Alanine-tRNA Ligase, Deuterium Exchange Measurement, Biological Sciences, Neuropilin-1, Recombinant Proteins, 030104 developmental biology, Transfer RNA, AlaRS, 030217 neurology & neurosurgery, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd45dff9c50fd9cf3a512aba7650922Test
https://doi.org/10.1073/pnas.2012898118Test

المؤلفون: Aidan R. Cole, Daisy W. Leung, Preston J. Kim, Michael L. Gross, Gaya K. Amarasinghe, Angela J. Zou, Zbyszek Otwinowski, Jingjing Pei, Srirupa Chatterjee, Nicole D. Wagner, Christopher F. Basler, Dominika Borek

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: 0301 basic medicine, Interferon-Induced Helicase, IFIH1, viruses, 030106 microbiology, Viral Nonstructural Proteins, Crystallography, X-Ray, Virus, 03 medical and health sciences, Ubiquitin, Interferon, medicine, Humans, RNA, Messenger, Receptors, Immunologic, Receptor, Messenger RNA, Multidisciplinary, biology, Chemistry, virus diseases, Deuterium Exchange Measurement, MDA5, Interferon-beta, biochemical phenomena, metabolism, and nutrition, Biological Sciences, Cell biology, N-terminus, 030104 developmental biology, HEK293 Cells, biology.protein, DEAD Box Protein 58, Antagonism, medicine.drug, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fe0d0ddf38515d3a9ee7f3e5da585aTest
https://pubmed.ncbi.nlm.nih.gov/33649232Test

المؤلفون: Kandala V. R. Chary, Shrikant Sharma, Khandekar Jishan Bari

المصدر: Biochemical and Biophysical Research Communications. 514:901-906

مصطلحات موضوعية: 0301 basic medicine, High resolution nmr, Protein Conformation, Biophysics, Cataract formation, Molecular Dynamics Simulation, Biochemistry, Chemical kinetics, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Crystallin, Amide, Humans, Point Mutation, gamma-Crystallins, Nuclear Magnetic Resonance, Biomolecular, Molecular Biology, Protein Unfolding, Chemistry, Deuterium Exchange Measurement, Cell Biology, Nuclear magnetic resonance spectroscopy, eye diseases, Infantile cataract, 030104 developmental biology, 030220 oncology & carcinogenesis, Free energies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d57e1a6af524de2e2f39b49e3aea3fTest
https://doi.org/10.1016/j.bbrc.2019.05.029Test

المؤلفون: Thomas E. Wales, John R. Engen, Donald F. Becker, Angela S. Fleischhacker, Stephen W. Ragsdale, Brent A. Kochert

المصدر: J Biol Chem

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Conformational change, Heme binding, Amino Acid Motifs, Heme, Molecular Dynamics Simulation, Biochemistry, Cofactor, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, Humans, Molecular Biology, 030102 biochemistry & molecular biology, biology, Protein dynamics, Deuterium Exchange Measurement, Cell Biology, Heme oxygenase, 030104 developmental biology, Membrane protein, chemistry, Protein Structure and Folding, Heme Oxygenase (Decyclizing), Biophysics, biology.protein, Protein Multimerization, Heme Oxygenase-1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6209c2036618be2af1103dfc41171a2Test
https://doi.org/10.1074/jbc.ra119.008592Test

المؤلفون: Jiang Zhu, Rui Hu, Xu Zhang, Haijie Yao, Shuangli Li, Yunhuang Yang, Maili Liu, Xin Zhou, Dong Long, Fan Luo

المصدر: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1866:1021-1028

مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, Magnetic Resonance Spectroscopy, Biophysics, 010402 general chemistry, 01 natural sciences, Biochemistry, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, Gene expression, Humans, Molecular Biology, Homeodomain Proteins, Base Sequence, Chemistry, Deuterium Exchange Measurement, Promoter, DNA, Nuclear magnetic resonance spectroscopy, 0104 chemical sciences, Repressor Proteins, NMR spectra database, 030104 developmental biology, Helix, Nucleic Acid Conformation, Homeobox, Sequence motif, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472c234a307bea69106312032f18bfe8Test
https://doi.org/10.1016/j.bbapap.2018.07.005Test

المؤلفون: van Galen, Josse, Freato, Nadia, Przeradzka, Małgorzata A, Ebberink, Eduard H T M, Boon-Spijker, Mariëtte, van der Zwaan, Carmen, van den Biggelaar, Maartje, Meijer, Alexander B, Biomolecular Mass Spectrometry and Proteomics, Afd Pharmaceutics, Afd Biomol.Mass Spect. and Proteomics, Pharmaceutics

المساهمون: Biomolecular Mass Spectrometry and Proteomics, Afd Pharmaceutics, Afd Biomol.Mass Spect. and Proteomics, Pharmaceutics

المصدر: Thrombosis and Haemostasis, 121(05), 594. Schattauer GmbH

مصطلحات موضوعية: 0301 basic medicine, Phospholipid, Molecular Conformation, Hemophilia A, Dissociation (chemistry), Cofactor, Mass Spectrometry, 03 medical and health sciences, chemistry.chemical_compound, Leucine, A2 domain retention, Humans, factor IXa, Surface plasmon resonance, Blood Coagulation, Factor VIIIa, hydrogen–deuterium exchange, Alanine, 030102 biochemistry & molecular biology, biology, Deuterium Exchange Measurement, Hematology, Surface Plasmon Resonance, Deuterium, interactive regions, 030104 developmental biology, Membrane, chemistry, factor VIII, biology.protein, Biophysics, Mutagenesis, Site-Directed, Tyrosine, Hydrogen–deuterium exchange, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071710f41e51aac04eca48e9e1aa3384Test
https://dspace.library.uu.nl/handle/1874/418734Test

المؤلفون: Derek J. Wilson, Stephen Li, Salvador F. Ausar, Thomas Bertrand, Jessica Duprez, Roger H. Brookes, Alexey Rak, D. Andrew James, Artur Pedyczak, Shaolong Zhu, Valerie Steier, Anthony Sheung, Michael X Cohen

المصدر: Communications Biology
'Communications Biology ', vol: 3, pages: 427-1-427-12 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: 0301 basic medicine, Protein vaccines, Protein Conformation, Whooping Cough, Protein subunit, Mutant, Medicine (miscellaneous), chemical and pharmacologic phenomena, CHO Cells, Pertussis toxin, Crystallography, X-Ray, complex mixtures, General Biochemistry, Genetics and Molecular Biology, Article, Bordetella pertussis, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Cricetulus, Cricetinae, Animals, Humans, Mass cytometry, lcsh:QH301-705.5, X-ray crystallography, Pertussis Vaccine, Mass spectrometry, Chemistry, Immunogenicity, Wild type, Deuterium Exchange Measurement, Toxoids, Molecular biology, 030104 developmental biology, lcsh:Biology (General), Pertussis Toxin, NAD+ kinase, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c21e5acfc882add69441d72d08636bTest
http://europepmc.org/articles/PMC7406505Test

المؤلفون: Josse van Galen, Alexander B. Meijer, Koen Mertens, Maartje van den Biggelaar, Eduard H T M Ebberink, Caroline Fribourg, Floris P. J. van Alphen, Mariëtte Boon-Spijker, Nadia Freato

المصدر: Blood. 136(23)

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, alpha-Helical, Immunology, Allosteric regulation, 030204 cardiovascular system & hematology, Biochemistry, Hemophilia B, Cofactor, Mass Spectrometry, law.invention, Factor IXa, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Protein Domains, law, Humans, chemistry.chemical_classification, Factor VIII, biology, Chemistry, Mutagenesis, Substrate (chemistry), Deuterium Exchange Measurement, Cell Biology, Hematology, 030104 developmental biology, Enzyme, Coagulation, Mutation, biology.protein, Recombinant DNA, Biophysics, Hydrogen–deuterium exchange

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78dafd5a8fbcc1d54a9078d1c0b504bTest
https://pubmed.ncbi.nlm.nih.gov/32678887Test

المؤلفون: Amrita Mitra, Dibyajyoti Maity, Debnath Pal, Cecil Ross, Amit Kumar Mandal, Gopa Mitra, Rajdeep Das, Vijay Bhat, Anura V Kurpad

المصدر: Biochemical Journal. 475:2153-2166

مصطلحات موضوعية: 0301 basic medicine, 030102 biochemistry & molecular biology, Chemistry, Hemoglobin, Sickle, Deuterium Exchange Measurement, Cell Biology, Molecular Dynamics Simulation, Glutathione, Biochemistry, Mass Spectrometry, 03 medical and health sciences, Molecular dynamics, 030104 developmental biology, Tetramer, Polymerization, Biophysics, Humans, Moiety, Hydrogen–deuterium exchange, Globin, Hemoglobin, Protein Multimerization, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59be94f35d5c097d11fca839e46ff1aTest
https://doi.org/10.1042/bcj20180306Test