نتائج البحث

1

miR-146a-5p suppresses ATP-binding cassette subfamily G member 1 dysregulation in patients with refractory Mycoplasma pneumoniae via interleukin 1 receptor-associated kinase 1 downregulation

المؤلفون: Hu‑Nian Li, Xu Zhao, Yong‑Jiu Zha, Liang Sun, Fang Du, Jie Liu

المصدر: International Journal of Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Male, Small interfering RNA, Mycoplasma pneumoniae, Inflammation, interleukin 1 receptor-associated kinase 1, medicine.disease_cause, Microbiology, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Pneumonia, Mycoplasma, Genetics, Medicine, Humans, RNA, Small Interfering, Child, ATP Binding Cassette Transporter, Subfamily G, Member 1, refractory Mycoplasma pneumoniae pneumonia, biology, business.industry, Kinase, Interleukin, Infant, microRNA-146a-5p, General Medicine, Articles, medicine.disease, respiratory tract diseases, Pneumonia, MicroRNAs, 030104 developmental biology, Interleukin-1 Receptor-Associated Kinases, Retinoid X Receptors, ABCG1, Gene Expression Regulation, A549 Cells, 030220 oncology & carcinogenesis, Child, Preschool, biology.protein, ATP-binding cassette subfamily G member 1, Female, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d427d0cac7eac5a49f9de7d2cc7f88a0Test
http://europepmc.org/articles/PMC6844629Test

2

CAR directs T cell adaptation to bile acids in the small intestine

المصدر: Nature

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, medicine.drug_class, T-Lymphocytes, medicine.medical_treatment, T cell, Receptors, Cytoplasmic and Nuclear, Article, Bile Acids and Salts, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Crohn Disease, Intestine, Small, medicine, Animals, Ileitis, ATP Binding Cassette Transporter, Subfamily B, Member 1, Receptor, Enterohepatic circulation, Constitutive Androstane Receptor, Inflammation, Multidisciplinary, Bile acid, Chemistry, medicine.disease, Small intestine, Interleukin-10, Cell biology, 030104 developmental biology, Cytokine, medicine.anatomical_structure, Gene Expression Regulation, Female, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f9859e3dc924c36f9f51ca55a06332Test
https://doi.org/10.1038/s41586-021-03421-6Test

3

Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice

المؤلفون: Zemin Yang, Jingpan Lin, Shuai Wang, Ziyue Zhou, Lu Gao, Baojian Wu, Huijie Xing, Yanke Lin, Shujing Ren

المصدر: Theranostics

مصطلحات موضوعية: 0301 basic medicine, Inflammasomes, RXR, Medicine (miscellaneous), Repressor, NF-κB, Mice, 03 medical and health sciences, Transactivation, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Transcription (biology), NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Animals, Immunoprecipitation, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), In Situ Hybridization, Fluorescence, Steatohepatitis, Platr4, Regulation of gene expression, Retinoid X Receptor alpha, Chemistry, NF-kappa B, RNA, Inflammasome, medicine.disease, NLRP3 inflammasome, Circadian Rhythm, Cell biology, 030104 developmental biology, Gene Expression Regulation, 030220 oncology & carcinogenesis, Nuclear Receptor Subfamily 1, Group D, Member 1, RNA, Long Noncoding, Research Paper, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6576ec0daa39a56a0120e54213857d82Test
https://doi.org/10.7150/thno.50281Test

4

Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC

المؤلفون: Johannes Loffing, Dominique Loffing-Cueni, Denise V. Kratschmar, Christina Schnoz, Sandra Moser, Alex Odermatt

المساهمون: University of Zurich, Loffing, Johannes

المصدر: Pflugers Archiv

مصطلحات موضوعية: 0301 basic medicine, Renal distal convoluted tubule (DCT), 10017 Institute of Anatomy, Physiology, Clinical Biochemistry, TRPM Cation Channels, 610 Medicine & health, 1308 Clinical Biochemistry, Kidney, 03 medical and health sciences, Mice, 2737 Physiology (medical), 0302 clinical medicine, Physiology (medical), TRPM6, medicine, Transcriptional regulation, Animals, Magnesium, Solute Carrier Family 12, Member 3, Distal convoluted tubule, Kidney Tubules, Distal, Transcription factor, Solute Carrier Family 12, Member 1, Homeodomain Proteins, Aquaporin 2, NaCl cotransporter (NCC), Chemistry, Kinase, Tumor Suppressor Proteins, DCT adaptation, Sodium, 1314 Physiology, Transient receptor potential cation channel subfamily M member 6 (TRPM6), Cell biology, body regions, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Transcription factor Prox-1, Potassium, 570 Life sciences, biology, Cotransporter, 030217 neurology & neurosurgery, Homeostasis, Ion Channels, Receptors and Transporters, Gene Deletion

وصف الملف: application/pdf; Schnoz2020_Article_DeletionOfTheTranscriptionFact.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ff553d8a385117c20f937280b5696fTest
http://europepmc.org/articles/PMC7782375Test

5

The nuclear receptor 4A family members: mediators in human disease and autophagy

المؤلفون: Fengtian Fan, Liqun Chen, Lingjuan Wu, Yiyi Zhao

المصدر: Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-15 (2020)
Cellular & Molecular Biology Letters

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47a6dc1aef659e7a2042e9d78521d57Test
http://link.springer.com/article/10.1186/s11658-020-00241-wTest

6

NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β‐cells for protection

المؤلفون: Dong Liu, Yuantao Liu, Chen Zong, Tian‐fu Yu, Esha Sadiq, Jie Cheng, Ze‐qing Pu, Yuchao Zhang, Xiangdong Wang, Xiao Yu, Ruxing Zhao, Cheng‐wen Jin, Dandan Qin, Xia Li, Jicui Chen, Hanse Pablick Patherny Lobo Mouguegue, Jing-Yu Lin, Qingbo Guan

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, MAP Kinase Kinase 4, cbl‐b, Models, Biological, Cell Line, Mice, 03 medical and health sciences, Transactivation, p‐JNK, 0302 clinical medicine, Insulin-Secreting Cells, Gene expression, Nuclear Receptor Subfamily 4, Group A, Member 1, Animals, Phosphorylation, Promoter Regions, Genetic, pancreatic β‐cells, Mice, Knockout, chemistry.chemical_classification, Reactive oxygen species, biology, Kinase, Endoplasmic reticulum, JNK Mitogen-Activated Protein Kinases, Ubiquitination, ROS, Original Articles, Hydrogen Peroxide, Cell Biology, Endoplasmic Reticulum Stress, Cell biology, Ubiquitin ligase, 030104 developmental biology, Gene Expression Regulation, chemistry, Apoptosis, 030220 oncology & carcinogenesis, Unfolded protein response, biology.protein, Molecular Medicine, Original Article, ER stress, Reactive Oxygen Species, NR4A1 (Nur77), Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c998067b9331388ff92e5634b301b9Test
https://doi.org/10.1111/jcmm.16028Test

7

Patrolling Monocytes Are Recruited and Activated by Diabetes to Protect Retinal Microvessels

المؤلفون: Francesco Tecilazich, G. Scotti, Zeina Dagher, Toan A. Phan, Mara Lorenzi, Fabio Simeoni

المصدر: Diabetes

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Complications, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Inflammation, CXCR4, Monocytes, Diabetes Mellitus, Experimental, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Downregulation and upregulation, Diabetes mellitus, Internal medicine, Nuclear Receptor Subfamily 4, Group A, Member 1, Internal Medicine, medicine, Animals, Mice, Knockout, Diabetic Retinopathy, business.industry, Microangiopathy, Retinal Vessels, Leukostasis, Retinal, Diabetic retinopathy, medicine.disease, 3. Good health, 030104 developmental biology, Endocrinology, Gene Expression Regulation, chemistry, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4d581835917411c04023cecbd91af4Test
https://doi.org/10.2337/db19-1043Test

8

Transporter-interfering chemicals inhibit P-glycoprotein of yellowfin tuna (Thunnus albacares)

المؤلفون: Steven D. Rees, Sascha C.T. Nicklisch, Geoffrey Chang, Aaron P. McGrath, Amara Pouv, Amro Hamdoun

المصدر: Comparative biochemistry and physiology. Toxicologypharmacology : CBP. 248

مصطلحات موضوعية: 0301 basic medicine, Physiology, Health, Toxicology and Mutagenesis, 010501 environmental sciences, Toxicology, Medical and Health Sciences, 01 natural sciences, Biochemistry, Yellowfin tuna, chemistry.chemical_compound, Water Pollutants, Cloning, Molecular, Phylogeny, Trophic level, Adenosine Triphosphatases, biology, Persistent organic pollutants, food and beverages, ABCB1, General Medicine, Biological Sciences, Bioaccumulation, Subfamily B, Liver, ABC transporter, fish physiology, Thunnus, Member 1, ATP Binding Cassette Transporter, Chemical, P-glycoprotein, DDT, 03 medical and health sciences, Fish physiology, Animals, ATP Binding Cassette Transporter, Subfamily B, Member 1, Transporter-interfering chemicals, Life Below Water, 0105 earth and related environmental sciences, Tuna, Molecular, Transporter, Cell Biology, biology.organism_classification, marine pollution, 030104 developmental biology, chemistry, Gene Expression Regulation, Endrin, human activities, Environmental Sciences, Water Pollutants, Chemical, Cloning

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1af7e200e92933d363a095004e28eb7Test
https://pubmed.ncbi.nlm.nih.gov/34116183Test

9

Long non-coding RNA MALAT1 regulates cholesterol accumulation in ox-LDL-induced macrophages via the microRNA-17-5p/ABCA1 axis

المؤلفون: Lili Tan, Lin Yang, Jian Yao, Limin Liu

المصدر: Molecular Medicine Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Apolipoprotein E, Cancer Research, THP-1 Cells, ABCA1, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, lncRNA, ATP Binding Cassette Transporter, Subfamily G, Member 1, Aged, 80 and over, Gene knockdown, biology, Articles, Middle Aged, Lipoproteins, LDL, Cholesterol, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Female, RNA, Long Noncoding, lipids (amino acids, peptides, and proteins), Signal Transduction, Adult, macrophage, Models, Biological, 03 medical and health sciences, Apolipoproteins E, cholesterol accumulation, microRNA, Genetics, Humans, Scavenger receptor, MALAT1, Molecular Biology, Aged, Messenger RNA, Base Sequence, Macrophages, Atherosclerosis, microRNA-17-5p, Molecular biology, MicroRNAs, 030104 developmental biology, Gene Expression Regulation, chemistry, biology.protein, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73095e9502fafb4cba4301b309309ba3Test
http://europepmc.org/articles/PMC7057819Test

10

Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy

المؤلفون: Yi Zhu, Xue-Jiao Sun, Xi-Qiong Han, Rui Yang, Naifeng Liu, Wen-Qi Ma

المصدر: Apoptosis. 25:321-340

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Clinical Biochemistry, Bone Morphogenetic Protein 2, Pharmaceutical Science, Core Binding Factor Alpha 1 Subunit, Mitochondrion, Mitochondrial Dynamics, 0302 clinical medicine, Mitochondrial Precursor Protein Import Complex Proteins, Mitophagy, Nuclear Receptor Subfamily 4, Group A, Member 1, RNA, Small Interfering, Aorta, Cholecalciferol, Gene knockdown, medicine.diagnostic_test, Chemistry, Cell biology, 030220 oncology & carcinogenesis, Mitochondrial fission, Signal Transduction, Dynamins, Nicotine, Receptors, Cell Surface, Diet, High-Fat, Streptozocin, Diabetes Mellitus, Experimental, Mitochondrial Proteins, 03 medical and health sciences, Organ Culture Techniques, Western blot, medicine, Animals, Lactic Acid, Rats, Wistar, Vascular Calcification, Pharmacology, Biochemistry (medical), Autophagy, Membrane Proteins, Membrane Transport Proteins, Cell Biology, medicine.disease, Rats, 030104 developmental biology, Gene Expression Regulation, Apoptosis, Tumor Suppressor Protein p53, Calcification

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03348a4e7c8661b51e39e2febd86b20fTest
https://doi.org/10.1007/s10495-020-01592-7Test

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