نتائج البحث - "Cohesin complex"

1

A cohesive look at leukemogenesis: The cohesin complex and other driving mutations in AML

المؤلفون: Katelyn E. Heimbruch, Aaron D. Viny, Sridhar Rao, Alison E. Meyer, Puja Agrawal

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 3, Pp 337-347 (2021)

مصطلحات موضوعية: 0301 basic medicine, Acute Myeloid Leukemia, Cancer Research, NPM1, Cohesin complex, Chromosomal Proteins, Non-Histone, Cell Cycle Proteins, lcsh:RC254-282, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Review article, Animals, Humans, Genetic Predisposition to Disease, Epigenetics, Regulation of gene expression, Genetics, Cohesin, biology, Myeloid leukemia, Oncogenes, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Chromatin Assembly and Disassembly, Chromatin, Leukemia, Myeloid, Acute, 030104 developmental biology, Histone, 030220 oncology & carcinogenesis, Mutation, biology.protein, gene expression, Disease Susceptibility, biological phenomena, cell phenomena, and immunity, Protein Multimerization, Carrier Proteins, Nucleophosmin, Mutations, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5d669c55587864b731bc62c7e0af60Test
http://europepmc.org/articles/PMC7905235Test

2

Towards a Better Understanding of Cohesin Mutations in AML

المؤلفون: Sergi Cuartero, Andrew J. Innes, Matthias Merkenschlager

المساهمون: Wellcome Trust, Medical Research Council (MRC), NIHR

المصدر: Frontiers in Oncology
Recercat. Dipósit de la Recerca de Catalunya
instname
Frontiers in Oncology, Vol 9 (2019)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cohesin complex, Mini Review, cohesin, KAPPA-B, Biology, lcsh:RC254-282, BONE-MARROW-CELLS, 03 medical and health sciences, 0302 clinical medicine, AML, SISTER-CHROMATID COHESION, medicine, HEMATOPOIETIC STEM-CELLS, 1112 Oncology and Carcinogenesis, GENE-EXPRESSION, Cohesin, Inflammation, Science & Technology, Leukemia, leukemia, Myeloid leukemia, interferon, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, MYELOID-LEUKEMIA CELLS, Phenotype, hematopoiesis, Cell biology, Chromatin, Hematopoiesis, REMODELING COMPLEX, Establishment of sister chromatid cohesion, SELF-RENEWAL, Haematopoiesis, 030104 developmental biology, EPIGENETIC REGULATORS, PROGENITOR CELLS, Oncology, inflammation, 030220 oncology & carcinogenesis, Interferon, Life Sciences & Biomedicine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf24c469f376319c2750503f83d282d5Test
https://hdl.handle.net/2072/445214Test

3

Chromatin-Spliceosome Mutations in Acute Myeloid Leukemia

المؤلفون: Yotaro Ochi, Seishi Ogawa

المصدر: Cancers, Vol 13, Iss 1232, p 1232 (2021)
Cancers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df82e9f2dc270ff82071c350d2a7b3dTest
https://www.mdpi.com/2072-6694/13/6/1232Test

4

Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML

المصدر: JCI Insight, Vol 6, Iss 3 (2021)
JCI Insight

مصطلحات موضوعية: 0301 basic medicine, Male, DNA Repair, Chromosomal Proteins, Non-Histone, Cell Cycle Proteins, Mice, SCID, Mouse models, chemistry.chemical_compound, Mice, 0302 clinical medicine, Mice, Inbred NOD, Tet methylcytosine dioxygenase 2, Nuclear Proteins, General Medicine, U937 Cells, Hematology, Chromatin, Leukemia, Myeloid, Acute, Oncology, 030220 oncology & carcinogenesis, Medicine, Epigenetics, Female, biological phenomena, cell phenomena, and immunity, Research Article, Cohesin complex, DNA damage, Mice, Transgenic, Biology, Poly(ADP-ribose) Polymerase Inhibitors, 03 medical and health sciences, Cell Line, Tumor, Leukemias, Animals, Humans, Replication protein A, Cohesin, Xenograft Model Antitumor Assays, Mice, Mutant Strains, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, chemistry, Myelodysplastic Syndromes, Mutation, Cancer research, Phthalazines, K562 Cells, DNA, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f284522b81d98cbd2e9c78a3b5f31aecTest
https://doaj.org/article/04d99d4ec50c41c1a8bc57f790a16758Test

5

Roles of NIPBL in maintenance of genome stability

المؤلفون: Bijun Zhu, Danyan Gao, Miaomiao Zhang, Xin Cao, Xiangdong Wang

المصدر: Seminars in Cell & Developmental Biology. 90:181-186

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5ff03c373580e4d00f615e071b889bTest
https://doi.org/10.1016/j.semcdb.2018.08.005Test

6

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression

المؤلفون: Julia Gerard, Bogdan Budnik, Jie Liu, Zhijun Duan, William Stafford Noble, Brian S. Kim, William S. Lane, Jung-Sik Kim, Todd Waldman, Xiaoyuan He, Taeyeon Kim, Manoj M. Pillai

المصدر: J Biol Chem

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd9d80769af33fc1491e3597eff7bc8Test
https://doi.org/10.1074/jbc.ra119.007832Test

7

Chronic Loss of STAG2 Leads to Altered Chromatin Structure Contributing to DE-Regulated Transcription in AML

المؤلفون: James S. Smith, Kienan Savage, Ken I. Mills, Simon S. McDade, Katrina M. Lappin, Alexander Thompson, Clare M. Crean, Stephanie G Craig, Fabio G. Liberante

المصدر: Journal of Translational Medicine
Smith, J, Lappin, K, Craig, S, Liberante, F, McDade, S, Thompson, A, Mills, K & Savage, K 2020, ' Chronic loss of STAG2 leads to altered chromatin structure contributiong to de-regulated transcription in AML ', JOURNAL OF TRANSLATIONAL MEDICINE, vol. 18, pp. 339-357 . https://doi.org/10.1186/s12967-020-02500-yTest
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-18 (2020)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cohesin complex, STAG2, lcsh:Medicine, Cell Cycle Proteins, Locus (genetics), Biology, HiChIP, Genome, General Biochemistry, Genetics and Molecular Biology, Acute myeloid leukaemia, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Gene expression, Humans, Hox gene, Gene, Loss function, Genetics, Biochemistry, Genetics and Molecular Biology(all), Research, lcsh:R, MAPK pathway, General Medicine, HOX, Chromatin, Cell biology, ChIP-seq, Leukemia, Myeloid, Acute, 030104 developmental biology, 030220 oncology & carcinogenesis, Myelodysplastic Syndromes, Mutation, Cohesion, Human genome, RNA-seq, Functional genomics