نتائج البحث - "MYCOLACTONE"

1

Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

المؤلفون: Thomas Laval, Sarah Saint-Auret, Ivo G. Boneca, Laurent Boucontet, Caroline Demangel, Jean-Pierre Levraud, Laure Guenin-Macé, Christophe Prehaud, Anaelle da Costa, Emma Colucci-Guyon, Aline Rifflet, Nicolas Blanchard

المساهمون: Macrophages et Développement de l’Immunité, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Biologie et Génétique de la Paroi bactérienne - Biology and Genetics of Bacterial Cell Wall, Laboratoire d'innovation moléculaire et applications (LIMA), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Neuro-Immunologie Virale - Viral Neuro-immunology, Immunobiologie de l'Infection - Immunobiology of Infection, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot, Sorbonne Paris Cité, Paris, France, Université Paris Diderot - Paris 7 (UPD7), This work was supported by the Institut Pasteur 'Microbes & Brain' collaborative project (LGM) and the Fondation Raoul Follereau (CD), core support from Institut Pasteur and INSERM (U1221). This study has received funding from the French Government’s Investissement d’Avenir program, Laboratoire d’Excellence 'Integrative Biology of Emerging Infectious Diseases' (grant n °ANR-10-LABX-62-IBEID) (IGB). AR was support by a post-doctoral fellowship from the Laboratoire d’Excellence 'Integrative Biology of Emerging Infectious Diseases. T.L. was a BioSPC-Université Paris Diderot PhD student, recipient of doctoral fellowships from the Ministère français de l’Enseignement Supérieur, de la Recherche et de l’Innovation (2016–2019) and Fondation pour la Recherche Médicale (FDT201904008040)., We thank the Image Analysis Hub of the Institut Pasteur for help with image analysis. We are grateful to Laurent Marsollier for the malaysian human isolate M. ulcerans 1615 and to Tim Stinear for the bioluminescent strain of M.ulcerans., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008878 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2020, 14 (12), pp.e0008878. ⟨10.1371/journal.pntd.0008878⟩
PLoS Neglected Tropical Diseases, 2020, 14 (12), pp.e0008878. ⟨10.1371/journal.pntd.0008878⟩

مصطلحات موضوعية: Central Nervous System, Bacterial Diseases, 0301 basic medicine, Buruli ulcer, Life Cycles, [SDV]Life Sciences [q-bio], RC955-962, Nervous System, chemistry.chemical_compound, Larvae, Medical Conditions, 0302 clinical medicine, Animal Cells, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Mycolactone, Buruli Ulcer, Zebrafish, biology, Optical Imaging, Eukaryota, Animal Models, 3. Good health, Cell biology, Actinobacteria, Infectious Diseases, medicine.anatomical_structure, Experimental Organism Systems, Osteichthyes, Blood-Brain Barrier, Larva, Mycobacterium ulcerans, Vertebrates, Physical Sciences, [SDV.IMM]Life Sciences [q-bio]/Immunology, Macrolides, Cellular Types, Anatomy, Public aspects of medicine, RA1-1270, Research Article, Neglected Tropical Diseases, Imaging Techniques, Materials Science, Material Properties, Bacterial Toxins, Central nervous system, Glial Cells, Research and Analysis Methods, Blood–brain barrier, Permeability, Cell Line, 03 medical and health sciences, Model Organisms, Spatio-Temporal Analysis, In vivo, Fluorescence Imaging, medicine, Animals, Humans, Microglial Cells, Bacteria, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Endothelial Cells, Cell Biology, Tropical Diseases, biology.organism_classification, medicine.disease, In vitro, Fish, 030104 developmental biology, chemistry, Astrocytes, Animal Studies, Zoology, 030217 neurology & neurosurgery, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ff524e2850e7ca4484b259cbe51f7eTest
https://doaj.org/article/26282b15277245c594cb443803d75fe7Test

2

Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection

المؤلفون: Joana Azeredo, Jorge Pedrosa, Hugo Alexandre Mendes Oliveira, Umender Sharma, Rita Silva-Gomes, Madhavi Hebbur, Alexandra G. Fraga, António G. Castro, Gabriela Trigo, Carine M. Gonçalves, Juan Dominguez, Ramya K. Murthy, Shamim Akhtar, Ana Rita Pacheco

المساهمون: Universidade do Minho

المصدر: PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007113 (2019)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: Bacterial Diseases, 0301 basic medicine, Buruli ulcer, Physiology, Polymers, RC955-962, Lysin, Mycobacterium Bovis, chemistry.chemical_compound, 0302 clinical medicine, Immune Physiology, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Mycolactone, Buruli Ulcer, Materials, Mice, Inbred BALB C, Innate Immune System, biology, Animal Models, Antimicrobial, Recombinant Proteins, 3. Good health, Actinobacteria, Chemistry, Treatment Outcome, Infectious Diseases, Experimental Organism Systems, Macromolecules, Lytic cycle, Mycobacterium ulcerans, Physical Sciences, Cytokines, Female, Public aspects of medicine, RA1-1270, Research Article, Neglected Tropical Diseases, Ciências da Saúde [Ciências Médicas], Ciências Médicas::Ciências da Saúde, Immunology, Materials Science, 030231 tropical medicine, Mouse Models, Research and Analysis Methods, Microbiology, Mycobacterium tuberculosis, Interferon-gamma, 03 medical and health sciences, Bacteriolysis, Model Organisms, Endopeptidases, medicine, Animals, Animal Models of Disease, Science & Technology, Bacteria, Tumor Necrosis Factor-alpha, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Mycobacteriophages, Molecular Development, Peptidoglycans, Tropical Diseases, Polymer Chemistry, biology.organism_classification, medicine.disease, Disease Models, Animal, Animal Models of Infection, 030104 developmental biology, chemistry, Immune System, Animal Studies, Lymph Nodes, Peptidoglycan, Mycobacterium Tuberculosis, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8b6f18a58166f5c5fd774a22ff6b8cTest
https://doaj.org/article/be335171665840bbb480559a2a6a4957Test

3

A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia

المؤلفون: Mark S. Pearson, Brenda Govan, Scott A. Ritchie, Avishek Singh, William J. H. McBride

المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0006745 (2019)

مصطلحات موضوعية: 0301 basic medicine, Buruli ulcer, Bacterial Diseases, Endemic Diseases, Artificial Gene Amplification and Extension, Disease Vectors, Pathology and Laboratory Medicine, Mosquitoes, Polymerase Chain Reaction, law.invention, Geographical Locations, chemistry.chemical_compound, 0302 clinical medicine, law, Medicine and Health Sciences, Mycolactone, Buruli Ulcer, DNA extraction, Polymerase chain reaction, Ulcers, Transmission (medicine), lcsh:Public aspects of medicine, Eukaryota, Gene Pool, Actinobacteria, Insects, Infectious Diseases, Mycobacterium ulcerans, Gene pool, Queensland, Research Article, Neglected Tropical Diseases, DNA, Bacterial, lcsh:Arctic medicine. Tropical medicine, Arthropoda, lcsh:RC955-962, 030231 tropical medicine, Oceania, Zoology, Mosquito Vectors, Biology, 03 medical and health sciences, Extraction techniques, Signs and Symptoms, Diagnostic Medicine, medicine, Genetics, Animals, Humans, Molecular Biology Techniques, Molecular Biology, Evolutionary Biology, Bacteria, Population Biology, Diptera, fungi, Public Health, Environmental and Occupational Health, Organisms, Australia, Biology and Life Sciences, lcsh:RA1-1270, biology.organism_classification, medicine.disease, Tropical Diseases, Invertebrates, Insect Vectors, Research and analysis methods, Species Interactions, 030104 developmental biology, chemistry, Vector (epidemiology), People and Places, Population Genetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16193c299df361de04098ba42ec66d8Test
https://pubmed.ncbi.nlm.nih.gov/30789904Test

4

Mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer

المؤلفون: Paul D R Johnson, Till F. Omansen, Jason K. Axford, Sacha J. Pidot, Jessica L. Porter, Renee Marcsisin, Timothy P. Stinear, Kirstie M. Mangas, Brian O. Howden, Weiguang Zeng, John R. Wallace

المصدر: PLoS Neglected Tropical Diseases, Vol 11, Iss 4, p e0005553 (2017)
PLoS Neglected Tropical Diseases, 11(4). PUBLIC LIBRARY SCIENCE
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: Bacterial Diseases, 0301 basic medicine, Buruli ulcer, SOUTHEASTERN AUSTRALIA, Disease Vectors, Skin infection, Mosquitoes, DISEASE, Geographical Locations, chemistry.chemical_compound, 0302 clinical medicine, NAUCORIS-CIMICOIDES, Aedes, MYCOLACTONE, Medicine and Health Sciences, BENIN, EPIDEMIOLOGY, Needlestick Injuries, Mycolactone, Buruli Ulcer, Mice, Inbred BALB C, biology, Infectious dose, lcsh:Public aspects of medicine, Animal Models, 3. Good health, Actinobacteria, Insects, Infectious Diseases, GHANA, Experimental Organism Systems, Mycobacterium ulcerans, Female, Research Article, Neglected Tropical Diseases, Skin Infections, lcsh:Arctic medicine. Tropical medicine, Arthropoda, lcsh:RC955-962, Oceania, 030231 tropical medicine, Mouse Models, Dermatology, Aedes aegypti, Aedes Aegypti, Research and Analysis Methods, Insect bites and stings, Microbiology, 03 medical and health sciences, Model Organisms, medicine, Animals, Bacteria, IDENTIFICATION, Organisms, Australia, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Insect Bites and Stings, lcsh:RA1-1270, Tropical Diseases, biology.organism_classification, medicine.disease, Invertebrates, ENVIRONMENTAL-SAMPLES, Insect Vectors, Species Interactions, 030104 developmental biology, chemistry, People and Places, RISK-FACTORS