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المؤلفون: Catherine Mooney, Norman Delanty, Sebastian Bauer, Mona Heiland, Thomas D.M. Hill, Gary P. Brennan, Hany El-Naggar, Cristina R. Reschke, Amaya Sanz-Rodriguez, David C. Henshall, Eva M. Jimenez-Mateos, Elizabeth Brindley, Jochen H. M. Prehn, Federico Del Gallo, Rana Raoof, Felix Rosenow, Paolo F. Fabene, Niamh M. C. Connolly, Omar Mamad, Lara Sophie Costard, Aasia Batool, Braxton A. Norwood, Beatrice Salvetti, Tobias Engel, Valentin Neubert
المصدر: Neurobiology of Disease, Vol 144, Iss, Pp 105048-(2020)
مصطلحات موضوعية: 0301 basic medicine, Male, Perforant Pathway, Muscarinic Agonists, Bioinformatics, Epileptogenesis, Temporal lobe, lcsh:RC321-571, Pathogenesis, 03 medical and health sciences, Epilepsy, Mice, 0302 clinical medicine, microRNA, Gene expression, Excitatory Amino Acid Agonists, Medicine, Animals, Circulating MicroRNA, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Kainic Acid, business.industry, Pilocarpine, MicroRNA, medicine.disease, Electric Stimulation, Rats, Disease Models, Animal, 030104 developmental biology, Neurology, Epilepsy, Temporal Lobe, Blood-Brain Barrier, Biomarker (medicine), Anticonvulsants, business, 030217 neurology & neurosurgery, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e169184f3937adac56d23d9a3560e3abTest
https://pubmed.ncbi.nlm.nih.gov/32800995Test -
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المؤلفون: Sebastian Bauer, Rainer Hamacher
المصدر: Current Opinion in Oncology. 29:275-285
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pathology, medicine.medical_specialty, Medizin, Computational biology, Biology, Translational Research, Biomedical, 03 medical and health sciences, 0302 clinical medicine, Genome editing, Cell Line, Tumor, medicine, Animals, Humans, CRISPR, Genetically engineered, Mesenchymal stem cell, Sarcoma, Sleeping Beauty transposon system, medicine.disease, Clinical trial, 030104 developmental biology, Oncology, Cell culture, 030220 oncology & carcinogenesis, Heterografts
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724012199708777b9a717473e4435a48Test
https://doi.org/10.1097/cco.0000000000000373Test -
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المؤلفون: Cristina R. Reschke, Ayla Aksoy-Aksel, Norman Delanty, Morten T. Venø, Thomas Braun, Sebastian Bauer, Braxton A. Norwood, Michael A. Farrell, Donncha F. O’Brien, Roberto Fiore, Franziska Metge, Christoph Dieterich, Rana Raoof, Silvia Bicker, Felix Rosenow, David C. Henshall, Gary P. Brennan, Gerhard Schratt, Marcus Krüger, Marek Rajman, Sharof Khudayberdiev, Jørgen Kjems
المصدر: Rajman, M, Metge, F, Fiore, R, Khudayberdiev, S, Aksoy-Aksel, A, Bicker, S, Reschke, C R, Raoof, R, Brennan, G P, Delanty, N, Farrell, M A, O'Brien, D F, Bauer, S, Norwood, B, Veno, M T, Krueger, M, Braun, T, Kjems, J, Rosenow, F, Henshall, D C, Dieterich, C & Schratt, G 2017, ' A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses ', E M B O Journal, vol. 36, no. 12, pp. 1770-1787 . https://doi.org/10.15252/embj.201695748Test
مصطلحات موضوعية: Doublecortin Domain Proteins, 0301 basic medicine, Proteome, MICRORNAS, RNA-binding protein, Bioinformatics, Hippocampus, Epileptogenesis, Mice, SYNAPTIC PLASTICITY, Homeostatic plasticity, Picrotoxin, Synaptic scaling, microRNA, biology, General Neuroscience, Articles, Crosstalk (biology), Excitatory postsynaptic potential, RNA Splicing Factors, Microtubule-Associated Proteins, EXPRESSION, Doublecortin Protein, PROTEINS, AMPA receptor, General Biochemistry, Genetics and Molecular Biology, homeostatic plasticity, Plasma Membrane Calcium-Transporting ATPases, 03 medical and health sciences, Animals, synaptic scaling, VISUAL-CORTEX, Molecular Biology, General Immunology and Microbiology, AMPA RECEPTORS, Gene Expression Profiling, Neuropeptides, STATUS EPILEPTICUS, Computational Biology, MAMMALIAN BRAIN, Doublecortin, MicroRNAs, 030104 developmental biology, Gene Expression Regulation, MESSENGER-RNA LOCALIZATION, Synapses, Synaptic plasticity, biology.protein, epilepsy, DENDRITIC SPINE DEVELOPMENT, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46fb481b7f9a93f21613c2cc0cffbd33Test
https://doi.org/10.15252/embj.201695748Test -
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المؤلفون: Seongju Yun, Cheol Keun Park, Min Goo Lee, Won Kyu Kim, Hoguen Kim, Jiyoon Kim, Sebastian Bauer
المصدر: Clinical Cancer Research. 23:845-856
مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Cancer Research, Pathology, medicine.medical_specialty, Stromal cell, Gastrointestinal Stromal Tumors, Mutant, Medizin, Golgi Apparatus, Kaplan-Meier Estimate, Biology, Endoplasmic Reticulum, medicine.disease_cause, Disease-Free Survival, Cell Line, 03 medical and health sciences, symbols.namesake, medicine, Animals, Humans, RNA, Small Interfering, Protein kinase C, Gastrointestinal Neoplasms, GiST, Endoplasmic reticulum, Transfection, Golgi apparatus, Neoplasm Proteins, Enzyme Activation, Gene Expression Regulation, Neoplastic, Proto-Oncogene Proteins c-kit, 030104 developmental biology, Oncology, Protein Kinase C-theta, Mutation, Proteolysis, symbols, Cancer research, RNA Interference, Carcinogenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81d36bbd1615bf4fa68fba5828dc1dfTest
https://doi.org/10.1158/1078-0432.ccr-16-0521Test -
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المؤلفون: Sebastian Bauer, Hajo M. Hamer
المصدر: Epilepsy research. 153
مصطلحات موضوعية: 0301 basic medicine, Vagus Nerve Stimulation, medicine.medical_treatment, Stimulation, law.invention, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Randomized controlled trial, law, Medicine, Animals, Humans, In patient, Seizure frequency, business.industry, Vagus Nerve, medicine.disease, Treatment period, Vagus nerve, 030104 developmental biology, Neurology, Anesthesia, Transcutaneous Electric Nerve Stimulation, Neurology (clinical), business, 030217 neurology & neurosurgery, Vagus nerve stimulation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a560b7730d9015c5c7f17f1c3d2d1b3dTest
https://pubmed.ncbi.nlm.nih.gov/30952581Test -
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المؤلفون: Gary P. Brennan, Catherine Mooney, Jochen H. M. Prehn, Hajo M. Hamer, Niamh M. C. Connolly, Elaine Spain, Sebastian Bauer, Felix Rosenow, Rana Raoof, Elizabeth Brindley, Thomas D.M. Hill, Hazel McArdle, Robert J. Forster, David C. Henshall, Norman Delanty, Hany El Naggar
المصدر: EBioMedicine
مصطلحات موضوعية: 0301 basic medicine, Serum, Research paper, False discovery rate, (FDR), Dissociative seizures, Bioinformatics, miRNA-target interactions, (MTIs), Status epilepticus, (SE), Noncoding RNA, Epilepsy, Mice, 0302 clinical medicine, Receiver operating characteristic, (ROC), Quantification cycle confidence, (Cqconf), Amplification score, (AmpScore), Gene Regulatory Networks, Preamplification, (preAmp), Temporal lobe epilepsy, Status epilepticus, epilepsy monitoring units, (EMUs), High-Throughput Nucleotide Sequencing, General Medicine, Human brain, Non-coding RNA, 3. Good health, Tags per Million, (TPM), medicine.anatomical_structure, Temporal lobe epilepsy, (TLE), Biomarker (medicine), medicine.symptom, OpenArray, (OA), Psychogenic non-epileptic seizures, (PNES), Control, (C), General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Epilepsy after-seizure sample, (EAS), microRNA, Biofluids, medicine, MicroRNAs, (miRNAs), Animals, Humans, ddc:610, Genetic generalized epilepsy, (GGE), Circulating MicroRNA, Anti-epileptic drugs, (AEDs), Electroencephalography, (EEG), Frontal lobe epilepsy, (FLE), Epilepsy baseline sample, (EBS), business.industry, Gene Expression Profiling, Computational Biology, Fluorescence in situ hybridization, (FISH), RNA sequencing, (RNA-seq), medicine.disease, Gene expression profiling, Disease Models, Animal, MicroRNAs, 030104 developmental biology, Epilepsy, Temporal Lobe, Case-Control Studies, Immunoprecipitation, (IP), business, Transcriptome, 030217 neurology & neurosurgery, Biomarkers
وصف الملف: Print-Electronic; application/octet-stream
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a755c9fdc51d2940f7714c28b64cf50Test
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المؤلفون: Sebastian Bauer, Johanna Falkenhorst, Michael Pogorzelski
المصدر: Current Opinion in Oncology. 28:331-337
مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Genotype, Gastrointestinal Stromal Tumors, Medizin, PDGFRA, 03 medical and health sciences, 0302 clinical medicine, Growth factor receptor, Internal medicine, medicine, Animals, Humans, Molecular Targeted Therapy, Stromal tumor, Genotyping, Gastrointestinal Neoplasms, GiST, business.industry, Imatinib, Clinical trial, 030104 developmental biology, Chemotherapy, Adjuvant, Fibroblast growth factor receptor, 030220 oncology & carcinogenesis, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150433dc34bb0212ebbe5c38cb750cc5Test
https://doi.org/10.1097/cco.0000000000000303Test -
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المؤلفون: Sebastian Bauer, Michael Heinrich, Suzanne George, Matthew L. Hemming
مصطلحات موضوعية: 0301 basic medicine, Gastrointestinal Stromal Tumors, medicine.drug_class, Medizin, PDGFRA, Tyrosine-kinase inhibitor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Regorafenib, Animals, Humans, Medicine, Stromal tumor, Protein Kinase Inhibitors, neoplasms, Gastrointestinal Neoplasms, GiST, business.industry, Sunitinib, Imatinib, Hematology, Prognosis, digestive system diseases, Proto-Oncogene Proteins c-kit, 030104 developmental biology, Imatinib mesylate, Oncology, chemistry, 030220 oncology & carcinogenesis, Mutation, Cancer research, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf913fcd83b4910d5d0ef101c0e4bbfTest
https://www.ncbi.nlm.nih.gov/pubmed/30101284Test -
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المؤلفون: Daniel Rauh, Hannah L. Tumbrink, Julia Ketzer, Sebastian Bauer, Carsten Schultz-Fademrecht, Julian Engel, Matthias Baumann, Stefano Tomassi, Marina Keul, Thomas Mühlenberg, Jonas Lategahn
المساهمون: Tomassi, S, Lategahn, J, Engel, J, Keul, M, Tumbrink, Hl, Ketzer, J, Mühlenberg, T, Baumann, M, Schultz-Fademrecht, C, Bauer, S, Rauh, D.
المصدر: Journal of medicinal chemistry. 60(6)
مصطلحات موضوعية: 0301 basic medicine, Indazoles, Lung Neoplasms, Phenotypic screening, EGFR, Mutant, Medizin, Antineoplastic Agents, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, T790M, Mice, Western blot, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Epidermal growth factor receptor, Lung, Protein Kinase Inhibitors, Indazole, biology, medicine.diagnostic_test, 010405 organic chemistry, Chemistry, Kinase, Molecular biology, Receptor–ligand kinetics, respiratory tract diseases, 0104 chemical sciences, ErbB Receptors, Molecular Docking Simulation, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, Cancer research, biology.protein, indazole, Molecular Medicine, covalent inhibitor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564158803e9ac4bea9d78338cb602b3bTest
https://pubmed.ncbi.nlm.nih.gov/28225269Test -
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المؤلفون: Matteo Caleo, Michael O. Poulter, Rafal M. Kaminski, Yuri Bozzi, Annamaria Vezzani, Braxton A. Norwood, Jan A. Gorter, Michele Mishto, Raymond Dingledine, Jean-Pierre Louboutin, Eleonora Aronica, Sookyong Koh, Sebastian Bauer, Gaetano Terrone, Eleonora Palma, David C. Henshall, Wolfgang Löscher, Daniela Kaufer
المساهمون: Aronica, Eleonora, Bauer, Sebastian, Bozzi, Yuri, Caleo, Matteo, Dingledine, Raymond, Gorter, Jan A., Henshall, David C., Kaufer, Daniela, Koh, Sookyong, Löscher, Wolfgang, Louboutin, Jean-Pierre, Mishto, Michele, Norwood, Braxton A., Palma, Eleonora, Poulter, Michael O., Terrone, Gaetano, Vezzani, Annamaria, Kaminski, Rafal M., ANS - Cellular & Molecular Mechanisms, Pathology, APH - Mental Health, APH - Aging & Later Life, Cellular and Computational Neuroscience (SILS, FNWI), SILS (FNWI)
المصدر: Aronica, E, Bauer, S, Bozzi, Y, Caleo, M, Dingledine, R, Gorter, J A, Henshall, D C, Kaufer, D, Koh, S, Löscher, W, Louboutin, J-P, Mishto, M, Norwood, B A, Palma, E, Poulter, M O, Terrone, G, Vezzani, A & Kaminski, R M 2017, ' Neuroinflammatory targets and treatments for epilepsy validated in experimental models ', Epilepsia, vol. 58 Suppl 3, pp. 27-38 . https://doi.org/10.1111/epi.13783Test
Epilepsia, 58(Suppl. 3), 27-38. Wiley-Blackwell
Epilepsia, vol 58 Suppl 3, iss Suppl 3
Epilepsia, 58(S3), 27-38. Wiley-Blackwellمصطلحات موضوعية: 0301 basic medicine, Anti-ictogenesis, Drug Resistant Epilepsy, antiepileptogenesis, Investigational, Review, Brain tissue, Neurodegenerative, Epileptogenesis, immune response, drugs, Epilepsy, 0302 clinical medicine, Inflammatory molecules, Anticonvulsant, 2.1 Biological and endogenous factors, Medicine, Anti-ictogenesi, Disease modification, animal, Aetiology, humans, neurology (clinical), Clinical Trials as Topic, clinical trials as topic, neurogenic inflammation, disease modification, Brain, Drugs, Antiepileptogenesis, animals, Drug development, Neurology, 5.1 Pharmaceuticals, dsease models, Neurological, anticonvulsants, Inflammatory pathways, Anticonvulsants, anti-ictogenesis, Development of treatments and therapeutic interventions, Antiepileptogenesi, Neurogenic Inflammation, Biotechnology, Human, brain, Clinical Sciences, Immune response, Inflammation, Animals, Drugs, Investigational, Humans, Disease Models, Animal, Neurology (clinical), drug development, epilepsy, inflammation, drug resistant epilepsy, drugs, investigational, dsease models, animal, neurology, investigational, Article, 03 medical and health sciences, Journal Article, Validation Studies, Neurology & Neurosurgery, business.industry, Animal, Neurosciences, medicine.disease, Brain Disorders, Clinical trial, 030104 developmental biology, Disease Models, business, Neuroscience, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594be612fc4e142d27c9df56a60c49a3Test
http://hdl.handle.net/11572/192013Test