التفاصيل البيبلوغرافية
العنوان:
SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease
المؤلفون:
Fernandez-Santiago, R. , Martin-Flores, N. , Antonelli, F. , Cerquera, C. , Moreno, V. , Bandres-Ciga, S. , Manduchi, E. , Tolosa, E. , Singleton, A.B. , Moore, J.H. , Noyce, A.J. , Kaiyrzhanov, R. , Middlehurst, B. , Kia, D.A. , Tan, M. , Houlden, H. , Morris, H.R. , Plun-Favreau, H. , Holmans, P. , Hardy, J. , Trabzuni, D. , Bras, J. , Quinn, J. , Mok, K.Y. , Kinghorn, K.J. , Billingsley, K. , Wood, N.W. , Lewis, P. , Schreglmann, S. , Guerreiro, R. , Lovering, R. , R'Bibo, L. , Manzoni, C. , Rizig, M. , Ryten, M. , Guelfi, S. , Escott-Price, V. , Chelban, V. , Foltynie, T. , Williams, N. , Morrison, K.E. , Clarke, C. , Brice, A. , Danjou, F. , Lesage, S. , Corvol, J.C. , Martinez, M. , Schulte, C. , Brockmann, K. , Simoon-Saanchez, J. , Heutink, P. , Rizzu, P. , Sharma, M. , Gasser, T. , Nicolas, A. , Cookson, M.R. , Blauwendraat, C. , Craig, D.W. , Faghri, F. , Gibbs, J.R. , Hernandez, D.G. , Keuren-Jensen, K. van , Shulman, J.M. , Iwaki, H. , Leonard, H.L. , Nalls, M.A. , Robak, L. , Lubbe, S. , Finkbeiner, S. , Mencacci, N.E. , Lungu, C. , Scholz, S.W. , Reed, X. , Alcalay, R.N. , Gan-Or, Z. , Rouleau, G.A. , Krohn, L. , Hilten, J.J. van , Marinus, J. , Adarmes-Goomez, A.D. , Aguilar, I. , Alvarez, I. , Alvarez, V. , Barrero, F.J. , Yarza, J.A.B. , Bernal-Bernal, I. , Blazquez, M. , Bonilla-Toribio, M. , Botia, J.A. , Boungiorno, M.T. , Buiza-Rueda, D. , Camara, A. , Carrillo, F. , Carrion-Claro, M. , Cerdan, D. , Clarimon, J. , Compta, Y. , Casa, B. de la , Diez-Fairen, M. , Dols-Icardo, O. , Duarte, J. , Duran, R. , Escamilla-Sevilla, F. , Ezquerra, M. , Feliz, C. , Fernandez, M. , Garcia, C. , Garcia-Ruiz, P. , Gomez-Garre, P. , Heredia, M.J.G. , Gonzalez-Aramburu, I. , Pagola, A.G. , Hoenicka, J. , Infante, J. , Jesus, S. , Jimenez-Escrig, A. , Kulisevsky, J. , Labrador-Espinosa, M.A. , Lopez-Sendon, J.L. , Arregui, A.L.D. , Macias, D. , Torres, I.M. , Marin, J. , Marti, M.J. , Martinez-Castrillo, C. , Mendez-del-Barrio, C. , Gonzalez, M.M. , Mata, M. , Minguez, A. , Mir, P. , Rezola, E.M. , Munoz, E. , Pagonabarraga, J. , Pascual-Sedano, B. , Pastor, P. , Errazquin, F.P. , Perinan-Tocino, T. , Ruiz-Martinez, J. , Ruz, C. , Rodriguez, A.S. , Sierra, M. , Suarez-Sanmartin, E. , Tabernero, C. , Tartari, J.P. , Tejera-Parrado, C. , Valldeoriola, F. , Vargas-Gonzalez, L. , Vela, L. , Vives, F. , Zimprich, A. , Pihlstrom, L. , Toft, M. , Koks, S. , Taba, P. , Hassin-Baer, S. , Malagelada, C. , Int Parkinson's Dis Genomics Conso
المساهمون:
Fundació La Marató de TV3, Michael J. Fox Foundation for Parkinson's Research, National Institutes of Health (US), Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España)
المصدر:
Mov Disord
سنة النشر:
2019
مصطلحات موضوعية:
0301 basic medicine , epistasis , Male , Parkinson's disease , very elderly , alpha-synuclein , Alpha‐synuclein , regulatory associated protein of mTOR , Cohort Studies , 0302 clinical medicine , single nucleotide polymorphism , genetics , Age of Onset , Genetics , Aged, 80 and over , Polymorphism, Single Nucleoti , biology , TOR Serine-Threonine Kinases , target of rapamycin kinase , fchsd1 gene , Age at onset , Chromosome Mapping , glycogen synthase kinase 3beta , Parkinson Disease , Middle Aged , cohort analysis , LRRK2 , priority journal , Neurology , chromosomal mapping , neuromodulation , mTOR , alpha-Synuclein , Female , age at onset , Signal Transduction , onset age , Adult , MTOR protein, human , protein kinase LKB1 , gene locus , Genotype , multifactor dimensionality reduction , SNP , Single-nucleotide polymorphism , rps6ka2 gene , Polymorphism, Single Nucleotide , Risk Assessment , Article , brain function , 03 medical and health sciences , alpha synuclein , medicine , Humans , controlled study , Genetic Predisposition to Disease , human , ddc:610 , SNCA protein, human , gene , Mechanistic target of rapamycin , PI3K/AKT/mTOR pathway , mammalian target of rapamycin , Aged , RPTOR , Epistasis, Genetic , Odds ratio , medicine.disease , major clinical study , nervous system diseases , 030104 developmental biology , mTOR signaling , biology.protein , Epistasis , pathology , Neurology (clinical) , genetic predisposition , 030217 neurology & neurosurgery
الوصف:
Special Issue: Focused Ultrasound in Parkinson's Disease.
تدمد:
1531-8257
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fab7d934f1f6ea0784330ea889bec1Test https://pubmed.ncbi.nlm.nih.gov/31234232Test
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....c0fab7d934f1f6ea0784330ea889bec1
قاعدة البيانات:
OpenAIRE
