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المؤلفون: Carmella Evans-Molina, Clive Wasserfall, Megan T Legge, Eleni Beli, Craig A. Beam, Ryan Silk, Kieran M. Mcgrail, Linda A. DiMeglio, Mark A. Atkinson, Stephanie Woerner, Maria B. Grant
المصدر: Diabetologia
Beam, C A, Beli, E, Wasserfall, C H, Woerner, S E, Legge, M T, Evans-Molina, C, McGrail, K M, Silk, R, Grant, M B, Atkinson, M A & DiMeglio, L A 2021, ' Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes ', Diabetologia . https://doi.org/10.1007/s00125-021-05468-6Testمصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, type 1 diabetes, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Circadian clock, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, Mice, 0302 clinical medicine, Cytotoxic T cell, education.field_of_study, B-Lymphocytes, Immune cells, Flow Cytometry, Circadian Rhythm, Cytokine, Type 1 diabetes, Female, Adult, Adolescent, Period (gene), Population, Biology, Chronobiology Disorders, circadian ryhtms, Article, 03 medical and health sciences, Clinical, Young Adult, Immune system, SDG 3 - Good Health and Well-being, Circadian Clocks, Internal Medicine, medicine, Animals, Humans, Circadian rhythms, Circadian rhythm, Lymphocyte Count, education, Interleukin-6, Dendritic Cells, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Diabetes Mellitus, Type 1, Immune System, Immunology, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5304384a2a7eb86434e13bd1acc63ddbTest
http://europepmc.org/articles/PMC8245361Test -
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المؤلفون: Nadir Kadri, Sarah J. Richardson, Lydia Sorokin, Eva Korpos, Sophie Loismann, Clais R. Findeisen, Noel G. Morgan, Alberto Pugliese, Frank Arfuso, George W. Burke, Marika Bogdani
المصدر: Diabetologia
مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Endocrinology, Diabetes and Metabolism, Autoimmunity, medicine.disease_cause, Mice, 0302 clinical medicine, Tertiary lymphoid organs, Mice, Inbred NOD, Child, NOD mice, Aged, 80 and over, Middle Aged, medicine.anatomical_structure, Type 1 diabetes, Fibroblastic reticular cells, Child, Preschool, Lymph node, Female, Beta cell, Adult, medicine.medical_specialty, Basement membrane, Adolescent, T cell, High endothelial venules, 030209 endocrinology & metabolism, Biology, Article, 03 medical and health sciences, Islets of Langerhans, Young Adult, Internal Medicine, medicine, Animals, Humans, Pancreas, B cell, Aged, Autoantibodies, Transplantation, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Tertiary Lymphoid Structures, Microscopy, Fluorescence, Reticular fibres, Insulitis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f333af12269efbba20d5e0fefe7a11dfTest
http://europepmc.org/articles/PMC8187221Test -
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المؤلفون: Amelia K. Linnemann, Charanya Muralidharan, Abass M. Conteh, Pascal de Boer, Jeroen Kuipers, Michelle Marasco, Justin J. Crowder
المصدر: Diabetologia, 64(4), 865-877. SPRINGER
Diabetologiaمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Autophagosome, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Autophagy-Related Proteins, Nod, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Insulin-Secreting Cells, Internal medicine, Diabetes mellitus, Macroautophagy, Internal Medicine, medicine, Autophagy, Animals, Humans, NOD mice, Proinsulin, Type 1 diabetes, business.industry, Autoantibody-positive, medicine.disease, Lysosome, Disease Models, Animal, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Crinophagy, Case-Control Studies, Female, Beta cell, Lysosomes, business, 030217 neurology & neurosurgery, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca8a2e71e6e61e43eb7bea2f3d7a3e4Test
https://doi.org/10.1007/s00125-021-05387-6Test -
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المؤلفون: Dun-Feng Xu, Yu-Jian Liu, Chu-Fan Xu, Yan Wang, Yan-Fei Mao, Lai Jiang, Xiao-Yan Zhu
المصدر: Journal of Cellular and Molecular Medicine
مصطلحات موضوعية: Male, 0301 basic medicine, thrombocytopenia, Apoptosis, Pharmacology, medicine.disease_cause, Mice, 0302 clinical medicine, Platelet, Cells, Cultured, platelet, Aged, 80 and over, chemistry.chemical_classification, Angiotensin II, Middle Aged, Prognosis, Losartan, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, Female, Signal Transduction, medicine.drug, Adult, Blood Platelets, reactive oxygen species (ROS), Receptor, Angiotensin, Type 1, Sepsis, 03 medical and health sciences, medicine, Animals, Humans, angiotensin II (Ang II), Aged, Cell Proliferation, Reactive oxygen species, Intrinsic apoptosis, angiotensin II receptor blocker (ARB), Original Articles, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Gene Expression Regulation, chemistry, Case-Control Studies, Reactive Oxygen Species, Angiotensin II Type 1 Receptor Blockers, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6123010f834858f85232068229ee63deTest
https://doi.org/10.1111/jcmm.16382Test -
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المؤلفون: Chin Wong, Thomas Gelzleichter, Junichiro Sonoda, Amos Baruch, Linda Morrow, Suresh Dheerendra, Leslie W. Chinn, Richard Boismenu, Eric Wakshull, Maria E. Wilson, Puneet S. Arora, Shan Chen, Anjali Vaze, Johnny Gutierrez, Nicholas Lewin-Koh
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: Male, 0301 basic medicine, obesity, Medical Sciences, FGF21, Adipose tissue, Mice, 0302 clinical medicine, Weight loss, Homeostasis, Medicine, Multidisciplinary, biology, Middle Aged, Biological Sciences, Adipose Tissue, Female, Adiponectin, Antibody, medicine.symptom, FGF21 receptor activation, Adult, Agonist, medicine.medical_specialty, Adolescent, medicine.drug_class, 030209 endocrinology & metabolism, Antibodies, Food Preferences, Young Adult, 03 medical and health sciences, Internal medicine, Weight Loss, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 1, Aged, business.industry, Fibroblast growth factor receptor 1, Body Weight, medicine.disease, Obesity, Fibroblast Growth Factors, stomatognathic diseases, Macaca fascicularis, 030104 developmental biology, Endocrinology, biology.protein, food preference, business, metabolism, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb1e6fc5999a3fd66bc3ad16e368b18Test
https://doi.org/10.1073/pnas.2012073117Test -
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المؤلفون: Diana Babaevskaya, Andrey Proshin, Igor Pomytkin, Margarita Oplatchikova, Tatyana Strekalova, Johannes P.J.M. de Munter, D. A. Pavlov, Allan V. Kalueff, Klaus-Peter Lesch, Ekaterina Lysikova, Anna Gorlova, Erik Ch. Wolters, Aleksei Umriukhin
المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience
المصدر: Journal of Cellular and Molecular Medicine, 24(17), 10251-10257. Wiley-Blackwell
Journal of Cellular and Molecular Medicine
J. Cell. Mol. Med.مصطلحات موضوعية: Male, Pathology, amyotrophic lateral sclerosis, PROTEIN EXPRESSION, EXPERIMENTAL NEUROINFLAMMATION, REAL TIME POLYMERASE CHAIN REACTION, MOUSE, ANIMAL EXPERIMENT, stem cell therapy, FUS[1‐359]‐tg mice, Mice, 0302 clinical medicine, SUCROSE PREFERENCE TEST, CELECOXIB, BRAIN, MUTATION, FUS[1-359]-tg mice, Neurons, RNA BINDING PROTEIN FUS, Behavior, Animal, celecoxib, LOCOMOTION, Neurodegeneration, TRANSGENIC MOUSE, Brain, DEPRESSION, Riluzole, Spinal Cord, 030220 oncology & carcinogenesis, RNA ISOLATION, CALCIUM BINDING PROTEIN, DRUG EFFECT, medicine.medical_specialty, Short Communication, Short Communications, FUS PROTEIN, MOUSE, IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1, BEHAVIOR, ANIMAL, INTERLEUKIN-1BETA, NEUROINFLAMMATION, 03 medical and health sciences, TAIL SUSPENSION TEST, NONHUMAN, Social Behavior, ELEVATED PLUS MAZE TEST, INTERLEUKIN 1BETA, FRONTOTEMPORAL LOBAR DEGENERATION, Glycogen Synthase Kinase 3 beta, animal model, ANIMALS, ANIMAL, medicine.disease, FUS[1-359]-TG MICE, Molecular medicine, 030104 developmental biology, Mutation, HIPPOCAMPUS, emotionality and cognition, CYCLOOXYGENASE 1, HOME-CAGE ACTIVITY TEST, ABNORMAL BEHAVIOR, SPINAL CORD, GELATINASE B, CYCLOOXYGENASE 2, 0301 basic medicine, MATRIX METALLOPROTEINASES, NERVE CELL, Interleukin-1beta, Anti-Inflammatory Agents, Hippocampus, PREFRONTAL CORTEX, ANIMAL MODEL, UNCLASSIFIED DRUG, neuroinflammation, MARBLE BURYING TEST, ANXIETY, COGNITIVE DEFECT, TISSUE INHIBITOR OF METALLOPROTEINASE 1, PLASTICITY, Amyotrophic lateral sclerosis, NEURONS, MOLECULAR MARKER, Frontotemporal lobar degeneration, STEM CELL, riluzole, Muscle atrophy, GENOTYPE, ANTIINFLAMMATORY ACTIVITY, frontotemporal lobar degeneration, BIOLOGICAL MARKER, GLYCOGEN SYNTHASE KINASE 3BETA, Molecular Medicine, AMYOTROPHIC LATERAL SCLEROSIS, RNA-BINDING PROTEIN FUS, medicine.symptom, ANTIINFLAMMATORY AGENT, medicine.drug, STEM CELL THERAPY, GLYCOGEN SYNTHASE KINASE 3 BETA, CAGE TEST, METABOLISM, ADULT, INFLAMMATION, WESTERN BLOTTING, ANIMAL TISSUE, GENE MUTATION, OPEN FIELD TEST, EMOTION, medicine, Animals, RESIDENT-INTRUDER TEST, ARTICLE, NERVE DEGENERATION, Neuroinflammation, Inflammation, MALE, TUMOR NECROSIS FACTOR, INTRACEREBROVENTRICULAR DRUG ADMINISTRATION, business.industry, SOCIAL BEHAVIOR, ANTI-INFLAMMATORY AGENTS, Cell Biology, FRONTOTEMPORAL DEMENTIA, ANIMAL BEHAVIOR, EMOTIONALITY AND COGNITION, CONTROLLED STUDY, MICE, GLYCOGEN SYNTHASE KINASE 3ALPHA, Cyclooxygenase 2, RILUZOLE, COGNITION, RNA-Binding Protein FUS, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06827f1ecd2f754817e6fe6568533e8Test
https://cris.maastrichtuniversity.nl/en/publications/0162d1c6-abc0-4610-83d0-566d46a45289Test -
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المؤلفون: Bin Zhou, Moli Huang, Ningyue Zhang, Lei Zhang, Fengying Wu, Zhiming Zhao, Shaomu Chen, Yali Chen, Anqi Li
المصدر: Cancer Letters. 485:14-26
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Lung Neoplasms, MAP Kinase Signaling System, medicine.medical_treatment, CD8-Positive T-Lymphocytes, Receptor, IGF Type 1, Mice, 03 medical and health sciences, Insulin-like growth factor, 0302 clinical medicine, Cell Line, Tumor, Immune Tolerance, medicine, Animals, Humans, Cytotoxic T cell, Lung cancer, Aged, Insulin-like growth factor 1 receptor, Aged, 80 and over, Chemistry, Middle Aged, V-Set Domain-Containing T-Cell Activation Inhibitor 1, medicine.disease, Gene Expression Regulation, Neoplastic, Mice, Inbred C57BL, body regions, 030104 developmental biology, Oncology, Tumor progression, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Female, Signal transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d9197cad7c5256237276c3d1dc6571Test
https://doi.org/10.1016/j.canlet.2020.04.013Test -
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المؤلفون: Zhenqiang Sun, Yuying Guo, Luyang Zhao, Xiaoke Wu, Dandan Fan, Zhenyu Ji, Bo Shao, Yaxin Guo, Chen Chen
المصدر: Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Molecular Cancerمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, circ3823, Colorectal cancer, Angiogenesis, In situ hybridization, Biology, Metastasis, Mice, 03 medical and health sciences, Colorectal cancer (CRC), 0302 clinical medicine, Cyclin D1, Tumour progression, In vivo, N6-methyladenosine (m6A), T Cell Transcription Factor 1, medicine, Animals, Humans, Neoplasm Invasiveness, RC254-282, Aged, Mice, Inbred BALB C, Neovascularization, Pathologic, Competing endogenous RNA, Cell growth, Research, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RNA, Circular, Middle Aged, medicine.disease, Gene Expression Regulation, Neoplastic, MicroRNAs, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Disease Progression, Cancer research, Heterografts, Molecular Medicine, Female, Colorectal Neoplasms, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c85c455f912a5e3bebdced397eb960bTest
https://doaj.org/article/8dfd9ece872d4308b8152a36847ba412Test -
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المؤلفون: Etienne Coyaud, Rahul Satija, Michelle Chan-Seng-Yue, John E. Dick, Héléna Boutzen, Alex Murison, Shin ichiro Takayanagi, Kerstin B. Kaufmann, Laura García-Prat, Andy G.X. Zeng, Kristele Pan, Olga I. Gan, Estelle M.N. Laurent, Sasan Zandi, Stephanie Z. Xie, Brian Raught, Jessica McLeod, Efthymia Papalexi
المساهمون: Princess Margaret Hospital, University of Toronto, Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U 1192 (PRISM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Ontario Institute for Cancer Research [Canada] (OICR), Ontario Institute for Cancer Research, INSERM, Université de Lille, Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192, Ontario Institute for Cancer Research [Canada] [OICR]
المصدر: Nature Immunology
Nature Immunology, 2021, Nature Immunology, 22, pp.723-734. ⟨10.1038/s41590-021-00925-1⟩مصطلحات موضوعية: Adult, Male, 0301 basic medicine, [SDV]Life Sciences [q-bio], Nectins, Primary Cell Culture, Transplantation, Heterologous, Immunology, Biology, Epigenesis, Genetic, Blood cell, Mice, 03 medical and health sciences, Immune Reconstitution, 0302 clinical medicine, Sirtuin 1, Downregulation and upregulation, Stress, Physiological, medicine, Animals, Humans, Immunology and Allergy, RNA-Seq, Epigenetics, Cell Self Renewal, Cells, Cultured, Immunomagnetic Separation, Multipotent Stem Cells, Hematopoietic Stem Cell Transplantation, Infant, Newborn, Intracellular Signaling Peptides and Proteins, Hematopoietic stem cell, Middle Aged, Fetal Blood, Flow Cytometry, Hematopoietic Stem Cells, Immune checkpoint, Hematopoiesis, Cell biology, Haematopoiesis, 030104 developmental biology, medicine.anatomical_structure, p21-Activated Kinases, Gene Knockdown Techniques, Protein deacetylase, Female, Single-Cell Analysis, Stem cell, 030215 immunology
وصف الملف: application/octet-stream
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ef12b6a4c072ab47ad871009ff3dcaTest
https://doi.org/10.1038/s41590-021-00925Test-1 -
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المؤلفون: Bo Ahrén, Giovanni Pacini
المصدر: Journal of Diabetes Investigation, Vol 12, Iss 5, Pp 675-685 (2021)
Journal of Diabetes Investigationمصطلحات موضوعية: 0301 basic medicine, Male, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Type 2 diabetes, Review Article, Mice, 0302 clinical medicine, Glucagon-Like Peptide 1, Insulin Secretion, Glucose homeostasis, Homeostasis, Insulin, Glucose disposal, General Medicine, Middle Aged, Administration, Intravenous, Female, Adult, medicine.medical_specialty, Incretin, 030209 endocrinology & metabolism, Gastric Inhibitory Polypeptide, Glucagon, Incretins, Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, Insulin resistance, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Animals, Humans, Aged, business.industry, Biological Transport, medicine.disease, RC648-665, Disease Models, Animal, 030104 developmental biology, Endocrinology, Glucose, Diabetes Mellitus, Type 2, Mathematical modeling, Insulin Resistance, Glucose effectiveness, business, Hormone
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67005bc300a2e7c1f06cc4eecdb76cefTest
https://doaj.org/article/e61653077b4a4f9199135797b3dd2507Test