المؤلفون: Hiroyuki Kawagishi, Mitsuhiko Yamada, Cheng-Kun Du, Tsutomu Nakada, Toshihide Kashihara, Sachio Morimoto, Elena E. Wolf, Shin Kadota, Takuro Numaga-Tomita, Yuji Shiba

المصدر: JACC: Basic to Translational Science

مصطلحات موضوعية: 0301 basic medicine, Inotrope, Agonist, PHF, pediatric heart failure, hiPSC-CM, human induced pluripotent stem cell–derived cardiac myocyte, medicine.drug_class, BBA, β-arrestin–biased angiotensin type 1 receptor agonist, 030204 cardiovascular system & hematology, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, ECG, electrocardiography, 0302 clinical medicine, ROS, reactive oxygen species, beta-arrestin-biased AT1 angiotensin receptor agonist, Renin–angiotensin system, Heart rate, medicine, OCR, oxygen consumption rate, Aldosterone, Angiotensin II receptor type 1, UCG, ultrasound cardiogram, business.industry, pediatric heart failure, AngII, angiotensin II, medicine.disease, human induced pluripotent stem cell-derived cardiac myocytes, inotropic vasodilator, Angiotensin II, human induced pluripotent stem cell–derived cardiac myocytes, congenital dilated cardiomyopathy, 030104 developmental biology, mNVCM, mouse neonatal ventricular cardiac myocyte, chemistry, β-arrestin–biased AT1 angiotensin receptor agonist, Heart failure, AT1R, angiotensin type 1 receptor, GPCR, G protein–coupled receptor, Preclinical Research, neonate, Cardiology and Cardiovascular Medicine, business, Editorial Comment, LTCC, CaV1.2 L-type Ca2+ channel, TRV027

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f2d81ed3d68f51843a352e270a974bTest
https://soar-ir.repo.nii.ac.jp/records/2001244Test

المؤلفون: Shio Mitsuzawa, Risako Ono, Mitsuru Ishikawa, Hiroya Ono, Rumiko Izumi, Masashi Aoki, Kensuke Ikeda, Ryo Funayama, Takefumi Sone, Matsuyuki Shirota, Shohei Kaneda, Hiroaki Mitsuhashi, Jiro Kawada, Akiyuki Ohno, Teruo Fujii, Hideyuki Okano, Satoru Morimoto, Ayumi Nishiyama, Keiko Nakayama, Shion Osana, Naoko Nakamura, Tomomi Shijo, Tetsuya Akiyama, Hitoshi Warita, Yoshiho Ikeuchi, Naoki Suzuki, Tadashi Nakagawa

المصدر: Stem Cell Reports

مصطلحات موضوعية: 0301 basic medicine, amyotrophic lateral sclerosis (ALS), Neurite, Induced Pluripotent Stem Cells, In situ hybridization, Biology, Biochemistry, TARDBP, Article, 03 medical and health sciences, 0302 clinical medicine, human-induced pluripotent stem cell (hiPSC)-derived motor neurons, Genetics, medicine, Animals, Humans, Axon, Amyotrophic lateral sclerosis, Zebrafish, Homeodomain Proteins, Motor Neurons, Gene knockdown, Amyotrophic Lateral Sclerosis, Cell Biology, Motor neuron, biology.organism_classification, medicine.disease, Axons, neurite length, Cell biology, DNA-Binding Proteins, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, nervous system, Gene Knockdown Techniques, Mutation, Transcriptome, 030217 neurology & neurosurgery, TAR-DNA binding protein (TARDBP), Transcription Factors, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9de8b5691c3559895f6932175691db1Test
https://doi.org/10.1016/j.stemcr.2021.04.021Test

المؤلفون: Yu Yamasaki, Daisuke Sasaki, Katsuhisa Matsuura, Tatsuya Shimizu

المصدر: Regenerative Therapy
Regenerative Therapy, Vol 18, Iss, Pp 66-75 (2021)

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), medicine.medical_specialty, ATP, adenosine triphosphate, Biomedical Engineering, Cardiomyopathy, Heart failure, DMEM, Dulbecco's Modified Eagle Medium, Contractile force, Re-oxygenation, PLN, phospholamban, Sarcomere, Biomaterials, 03 medical and health sciences, R5-920, 0302 clinical medicine, FBS, fetal bovine serum, Internal medicine, HFrEF, heart failure with reduced EF, HFpEF, heart failure with preserved EF, hiPSC-CMs, human induced pluripotent stem cell-derived cardiomyocytes, medicine, cTnT, cardiac troponin T, EF, ejection fraction, Induced pluripotent stem cell, Hypoxia, Ejection fraction, QH573-671, Chemistry, Human induced pluripotent stem cells, Hypoxia (medical), HFmrEF, heart failure with midrange EF, medicine.disease, Functional recovery, NPPA, natriuretic peptide precursor A, 030104 developmental biology, Cardiac cell sheet, SERCA, sarco/endoplasmic reticulum Ca2+ ATPase, Cardiology, Original Article, medicine.symptom, Cytology, 030217 neurology & neurosurgery, Function (biology), Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5213072fa8f409192c282b89daad06Test
http://europepmc.org/articles/PMC8044384Test

المؤلفون: Subha Subramanian, Gerine Jin-Ling Tong, Yuin-Han Loh, Shigeki Sugii, Thekkeparambil Chandrabose Srijaya, Tannistha Nandi, Qiao Rui Xing, Nam-Young Kang, Sandhya Sriram, Allen Chen, Samydurai Sudhagar, Patrick Tan, Young-Tae Chang

المصدر: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Stem Cell Research & Therapy

مصطلحات موضوعية: 0301 basic medicine, Cell type, Induced Pluripotent Stem Cells, Cell, Population, Adipose-derived stromal cell (ASC), Method, Medicine (miscellaneous), Biology, Biochemistry, Genetics and Molecular Biology (miscellaneous), lcsh:Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Human induced pluripotent stem cell (hiPSC), medicine, Dental pulp stem cell (DPSC), Tra-1-60, Humans, lcsh:QD415-436, Induced pluripotent stem cell, education, cAMP responsive element binding protein (CREB), Mesenchymal-epithelial transition (MET), Cells, Cultured, Fluorescent Dyes, DOFLA library fluorescence dye, education.field_of_study, lcsh:R5-920, Three-dimensional (3D) microcarrier-based culture system, Golgi marker, Cell Biology, Cell sorting, Cellular Reprogramming, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Cell culture, Early stage pluripotency, Molecular Medicine, Stem cell, Transcriptome, lcsh:Medicine (General), Reprogramming, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd6ace34223d1a4769636e583eb81fbTest
https://doaj.org/article/dc124a60d6274e229a1bcfaadff85571Test

المؤلفون: Ryota Tabei, Yujiro Kawai, Kazuaki Nakajima, Satoshi Kunita, Shota Someya, Jun Fujita, Hidenori Tani, Keiichi Fukuda, Yoshikazu Kishino, Hideaki Kanazawa, Shugo Tohyama, Takumi Teratani, Akira Ito, Noriko Handa, Akinori Hirano, Rei Shibata, Sho Tanosaki, Eiji Kobayashi, Shuji Hishikawa, Marina Okada, Hideyuki Shimizu, Masataka Yamazaki, Shigeo Okuda, Yoshitake Yamada, Yusuke Soma, Yasuhiko Tabata, Yuika Morita, Shinji Kawaguchi, Toyoaki Murohara

المصدر: JACC: Basic to Translational Science

مصطلحات موضوعية: 0301 basic medicine, Cardiac function curve, medicine.medical_specialty, LVEDV, left ventricular end-diastolic volume, Cell, heart failure, cardiomyocyte, 030204 cardiovascular system & hematology, HF, heart failure, human iPS cells, 03 medical and health sciences, 0302 clinical medicine, sCM, single cardiomyocyte, CMR, cardiac magnetic resonance, Internal medicine, hiPSC, human induced pluripotent stem cell, medicine, dp/dtmax, maximum rate of left ventricular pressure rise, EF, ejection fraction, CM, cardiomyocyte, Induced pluripotent stem cell, cell transplantation, LV, left ventricular, Ejection fraction, business.industry, Spheroid, medicine.disease, FAC, fractional area change, VEGF, vascular endothelial growth factor, Transplantation, 030104 developmental biology, medicine.anatomical_structure, GH, gelatin hydrogel, hPSC, human pluripotent stem cell, cardiac spheroids, Heart failure, Cardiology, LVESV, left ventricular end-systolic volume, ECG, electrocardiogram, Teratoma, Preclinical Research, Cardiology and Cardiovascular Medicine, business, CS, cardiac spheroid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd702f4cf6c1a7d7f095722276ed51f0Test
http://europepmc.org/articles/PMC7987543Test

المؤلفون: Satoshi Obika, Hideyuki Okano, Daisuke Ito, Masayuki Nakamori, Hayato Fukusumi, Hideki Mochizuki, Yonehiro Kanemura, Kazuyuki Togo, Tomoko Shofuda, Miho Sumida, Kousuke Baba

المصدر: FEBS Open Bio, Vol 11, Iss 2, Pp 354-366 (2021)
FEBS Open Bio

مصطلحات موضوعية: Lewy Body Disease, 0301 basic medicine, Parkinson's disease, DNA Copy Number Variations, Induced Pluripotent Stem Cells, Primary Cell Culture, Substantia nigra, Disease, Biology, human‐induced pluripotent stem cell, General Biochemistry, Genetics and Molecular Biology, SNCA triplication, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, dopaminergic neuron, Gene Duplication, PARK4, medicine, Humans, Induced pluripotent stem cell, lcsh:QH301-705.5, Gene, Cells, Cultured, Research Articles, Alpha-synuclein, α‐synuclein, Pars compacta, Dopaminergic Neurons, Dopaminergic, Cell Differentiation, Parkinson Disease, medicine.disease, Healthy Volunteers, nervous system diseases, 030104 developmental biology, lcsh:Biology (General), nervous system, chemistry, 030220 oncology & carcinogenesis, alpha-Synuclein, Cancer research, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d68d952eba4a115bea0812d9c37b9cTest
https://doi.org/10.1002/2211-5463.13060Test

المؤلفون: Ning Li, Jun Yang, Padmini Sirish, Deborah K. Lieu, Nilas Young, Bruce D. Hammock, Valeriy Timofeyev, Phung N. Thai, Ebenezer N. Yamoah, Sergey Yechikov, Douglas J. Rowland, Xiao-Dong Zhang, Svetlana Ganaga, Carol E. Nader, Kin Sing Stephen Lee, Lu Ren, Nipavan Chiamvimonvat, Jeong-Han Lee

المصدر: Stem Cells Translational Medicine

مصطلحات موضوعية: 0301 basic medicine, Epoxide hydrolase 2, human induced pluripotent stem cell derived‐cardiomyocytes, medicine.medical_treatment, Cell, cardiac stem cell‐based therapy, Mice, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Fibrosis, soluble epoxide hydrolase inhibitors, Animals, Humans, Gene silencing, Medicine, Myocytes, Cardiac, Induced pluripotent stem cell, CRISPR/Cas9, Epoxide Hydrolases, Inflammation, business.industry, Cell Biology, General Medicine, Stem-cell therapy, medicine.disease, Angiotensin II, myocardial infarction, 030104 developmental biology, medicine.anatomical_structure, Cancer research, Enabling Technologies for Cell‐based Clinical Translation, Stem cell, business, 030217 neurology & neurosurgery, Stem Cell Transplantation, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75f81c8c339891b05ca475a35a5a657Test
https://doi.org/10.1002/sctm.20-0143Test

المؤلفون: Anna Veiga, Barbara Ferreira-de-Souza, Anna Duarri, Helena Isla-Magrané, Diana Mora Ramírez, Miguel A Zapata, José García-Arumí, Laura Fontrodona, Angel Raya, Anna Badia, Anna Salas

المساهمون: Institut Català de la Salut, [Salas A, Fontrodona L, Ramírez DM, Badia A, Isla-Magrané H, Ferreira-de-Souza B, Zapata MÁ] Grup de Recerca en Oftalmologia, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Duarri A] Grup de Recerca en Oftalmologia, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. Barcelona Stem Cell Bank, Regenerative Medicine Program, IDIBELL, 08908 Hospitalet de Llobregat, Spain. National Stem Cell Bank-Barcelona Node, Biomolecular and Bioinformatics Resources Platform PRB2, ISCIII, 08908 Hospitalet de Llobregat, Spain. [García-Arumí J] Grup de Recerca en Oftalmologia, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. Servei d’Oftalmologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament d’Oftalmologia, Universitat Autònoma de Barcelona, Bellaterra, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Scientia
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Molecular Therapy. Methods & Clinical Development
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 688-702 (2021)

مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Photoreceptors, retinal pigment epithelium, Blindness, Cell therapy, human-induced pluripotent stem cell, chemistry.chemical_compound, 0302 clinical medicine, oftalmopatías::oftalmopatías::enfermedades de la retina::degeneración retiniana [ENFERMEDADES], Ceguesa, Human-induced pluripotent stem cell, RCS rat, Induced pluripotent stem cell, Rates (Animals de laboratori), Otros calificadores::/terapia [Otros calificadores], Eye Diseases::Eye Diseases::Retinal Diseases::Retinal Degeneration [DISEASES], iPSC, lcsh:Cytology, photoreceptors, Eukaryota::Animals::Chordata::Vertebrates::Mammals::Eutheria::Rodentia::Muridae::Murinae::Rats [ORGANISMS], Retinal diseases, Malalties de la retina, medicine.anatomical_structure, IPSC, 030220 oncology & carcinogenesis, Regenerative medicine, Molecular Medicine, Original Article, RPE, subretinal injection, Subretinal injection, medicine.medical_specialty, lcsh:QH426-470, Ratolins (Animals de laboratori), Retinal precursor cells, Cellular therapy, regenerative medicine, Eukaryota::animales::Chordata::vertebrados::mamíferos::Eutheria::Rodentia::Muridae::Murinae::ratas [ORGANISMOS], 03 medical and health sciences, Ophthalmology, Genetics, medicine, lcsh:QH573-671, Outer nuclear layer, Molecular Biology, Retinal pigment epithelium, Retina, Retina degeneration, business.industry, Teràpia cel·lular, Retinal, Other subheadings::/therapy [Other subheadings], medicine.disease, eye diseases, Transplantation, lcsh:Genetics, Mice (Laboratory animals), 030104 developmental biology, chemistry, retina degeneration, sense organs, cell therapy, Degeneració macular - Tractament, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7207e634aae6fa9795d6cffd8e160728Test
https://hdl.handle.net/11351/6539Test

المؤلفون: Virpi Talman, Marja Tölli, Mika J. Välimäki, S. Tuuli Karhu, Sini Kinnunen, Zoltan Szabo, Heikki Ruskoaho

المساهمون: Division of Pharmacology and Pharmacotherapy, Drug Research Program, Regenerative pharmacology group, Regenerative cardiac pharmacology

المصدر: Archives of Toxicology

مصطلحات موضوعية: Male, 0301 basic medicine, PHARMACOKINETICS, Time Factors, CELL-SURVIVAL, Health, Toxicology and Mutagenesis, Pharmacology, Toxicology, Ventricular Function, Left, Rats, Sprague-Dawley, 0302 clinical medicine, GATA4-targeted compounds, Natriuretic Peptide, Brain, Human induced pluripotent stem cell-derived cardiomyocytes, Myocytes, Cardiac, Chronic toxicity, GENE-EXPRESSION, Antibiotics, Antineoplastic, General Medicine, 3. Good health, BRAIN NATRIURETIC PEPTIDE, 317 Pharmacy, 030220 oncology & carcinogenesis, Toxicity, POSITION PAPER, Signal Transduction, CARDIAC HORMONES, medicine.drug, Heart Diseases, Cell Survival, Induced Pluripotent Stem Cells, Protective Agents, Cell Line, Organ Toxicity and Mechanisms, 03 medical and health sciences, Pharmacokinetics, In vivo, Transcription factors, medicine, Animals, Humans, Doxorubicin, Viability assay, Protein Precursors, Rats, Wistar, INDUCED CARDIOMYOPATHY, Cardiotoxicity, TRANSCRIPTION FACTORS GATA4, business.industry, Caspases, Effector, Stroke Volume, In vitro, GATA4 Transcription Factor, HYPERTROPHY, Disease Models, Animal, 030104 developmental biology, RAT, 1182 Biochemistry, cell and molecular biology, Cardioprotective, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7938cd515e8b9495355731c75fb01b1Test
https://doi.org/10.1007/s00204-020-02711-8Test

المؤلفون: Dongjin Wang, Jiaxian Wang, Qian Wang, Jiuyang Yu, Ruyi Zhang, Xumin Guan, Yunlong Xia, He Zhang, Wanzi Xu, Yamin Chen

المصدر: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2020)
Stem Cell Research & Therapy

مصطلحات موضوعية: 0301 basic medicine, Medicine (miscellaneous), Heart failure, 030204 cardiovascular system & hematology, Biochemistry, Genetics and Molecular Biology (miscellaneous), Regenerative medicine, lcsh:Biochemistry, 03 medical and health sciences, 0302 clinical medicine, medicine, lcsh:QD415-436, Induced pluripotent stem cell, Ventricular remodeling, Cardiomyocytes, lcsh:R5-920, business.industry, Research, Cell Biology, Myocardial function, medicine.disease, Remodeling, Cell biology, Transplantation, 030104 developmental biology, Molecular Medicine, Stem cell, business, lcsh:Medicine (General), Human induced pluripotent stem cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e4871772f528544c223dcdfcca8268Test
http://link.springer.com/article/10.1186/s13287-020-01602-0Test