المؤلفون: A. Cota-Coronado, O.R. Hernández-Pérez, Néstor F. Díaz, Pavel H. Lugo-Fabres, N. Emmanuel Díaz-Martínez, Valeria Valadez-Barba, Eduardo Padilla-Camberos

المصدر: Regenerative Therapy, Vol 15, Iss, Pp 332-339 (2020)
Regenerative Therapy

مصطلحات موضوعية: 0301 basic medicine, Neurodegenerative diseasaes, MHC, Mayor Histocompatibility Complex, Review, Disease, BBB, Blood Brain Barrier, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Human health, 0302 clinical medicine, B-III-TUB, β–III–Tubulin, TH, Tyrosine Hydroxylase, Medicine, PCR, Polymerase Chain Reaction, Parkinson, Induced pluripotent stem cell, lcsh:R5-920, hESC, Human Embryonic Stem Cells, lcsh:Cytology, iPSCs, Induced Pluripotent Stem Cells, EBs, Embryoid Bodies, PD, Parkinson's Disease, gRNA, guide RNA, nsSNVs, nonsynonymous single nucleotide variants, DOPAL, 3,4-Dihydroxyphenylacetaldehyde, FLASH, Fast Length Adjustment of Short Reads, AD, Alzheimer's disease, lcsh:Medicine (General), Biomedical Engineering, iPSCs, WGS, Whole Genome Sequencing, Cell fate determination, AFP, Alpha-Fetoprotein, Biomaterials, 03 medical and health sciences, lcsh:QH573-671, Aβ, β-Amyloid, pTau, Phosphorylated Tau, PD - Parkinson's disease, business.industry, SCs, Stem Cells, SNPc, Substantia Nigra Pars Compacta, Disease modelling, 030104 developmental biology, LUHMES, Lund Human Mesencephalic Cell Line, Alzheimer, Personalized medicine, AFP - Alpha-fetoprotein, SMA, Smooth-Muscle Antibody, business, Neuroscience, 030217 neurology & neurosurgery, ROS, Reactive Oxygen Species, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5533df458e5d5b5603371b246a30631cTest
http://www.sciencedirect.com/science/article/pii/S2352320420300894Test

المؤلفون: Dhivya Venkatesan, Arul Narayanasamy, Balachandar Vellingiri, Kamalakannan Siva, Mahalaxmi Iyer

المصدر: eNeurologicalSci
eNeurologicalSci, Vol 21, Iss, Pp 100270-(2020)

مصطلحات موضوعية: Kynurenine pathway, Parkinson's disease, AA, anthranilic acid, KMO, kynurenine −3-monooxygenase, FAM, formamidase, Disease, Review Article, Pharmacology, PD, Parkinson's disease, CSF, cerebrospinal fluid, lcsh:RC346-429, KYNA, kynurenic acid, Pathogenesis, chemistry.chemical_compound, 0302 clinical medicine, Kynurenic acid, NAD+, nicotinamide adenine dinucleotide, PA, picolinic acid, 3-HK, 3-hydroxykynurenine, XA, xanthurenic acid, IFN-γ, interferon-γ, 030212 general & internal medicine, QUIN, quinolinic acid, ACMSD, amino-carboxymuconatesemialdehyde decarboxylase, MPTP, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, 6-OHDA, 6-hydroxydopamine, LID, L-DOPA-induced dyskinesia, DA, dopaminergic, NMDA, N-methyl-d-aspartate, Neurology, AhR, aryl hydrocarbon receptor, AD, Alzheimer's disease, Parkinson's disease (PD), ATP, adenosine triphosphate, α-synuclein, αSyn, NFK, N′-formylkynurenine, Kynurenine pathway (KP), Therapeutics, CNS, central nervous system, TDO, tryptophan 2,3-dioxygenase, 03 medical and health sciences, medicine, KATs, kynurenine aminotransferases, lcsh:Neurology. Diseases of the nervous system, 3-HAA, 3-hydroxyanthranilic acid, L-DOPA, L-dopamine, business.industry, TRP, tryptophan, IDO-1, indoleamine-2,3-dioxygenases, ZNS, zonisamide, Neurotoxicity, KYN, kynurenine, NADPH, nicotinamide adenine dinucleotide phosphate, medicine.disease, KP, Kynurenine pathway, SNpc, substantianigra pars compacta, Metabolic pathway, Ageing, chemistry, RBCs, red blood cells, business, 030217 neurology & neurosurgery, Biomarkers, Quinolinic acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0784ecb2919785316b811e396b66d173Test
http://europepmc.org/articles/PMC7585940Test

المؤلفون: Qi Yuan Fan, Xi Min Fan, Ting Wang Xiong, Sheng Song, Jie Liu, Ying Luo, Yu Ming Cao

المصدر: Neurochemical Research

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Time Factors, Gene Expression, Substantia nigra, Biochemistry, Substantia nigra pars compacta (SNpc), Rats, Sprague-Dawley, Liver inflammation, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Internal medicine, Dopaminergic neuron loss, medicine, Manganism, Animals, Hepatic transporters, Neuroinflammation, Liver injury, Inflammation, Manganese, Original Paper, Microglia, Behavior, Animal, Pars compacta, Chemistry, Dopaminergic Neurons, Dopaminergic, Neurotoxicity, Brain, General Medicine, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Liver, Rotarod Performance Test, Neurotoxicity Syndromes, Chronic manganism, Chemical and Drug Induced Liver Injury, 030217 neurology & neurosurgery, Injections, Intraperitoneal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e67d9584dff2637e5cac00dbe4a29dTest
https://pubmed.ncbi.nlm.nih.gov/32488470Test

المؤلفون: Aditi Verma, Vijayalakshmi Ravindranath

المصدر: Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 11 (2020)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Aging, Cognitive Neuroscience, Substantia nigra, Cav1.3, lcsh:RC321-571, 03 medical and health sciences, chemistry.chemical_compound, alternative splicing, 0302 clinical medicine, Internal medicine, medicine, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, MPTP, biology, Tyrosine hydroxylase, Pars compacta, Calcium channel, Neurodegeneration, neurodegeneration, Brief Research Report, medicine.disease, SNpc, Ventral tegmental area, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, chemistry, nervous system, biology.protein, gene expression, CaV1.342A, 030217 neurology & neurosurgery, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6196850009f31c46784614b4a1ace977Test

المؤلفون: Yoshikage Muroi, Ken-ichi Kinoshita, Toshiaki Ishii

المصدر: International Journal of Molecular Sciences
Volume 20
Issue 21
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5340 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, hippocampus, animal diseases, Dopamine, Hippocampus, 5-ht4 receptor agonist, lcsh:Chemistry, chemistry.chemical_compound, Mice, 0302 clinical medicine, 5-HT4 receptor agonist, Cyclic AMP, Medicine, Serotonin 5-HT4 Receptor Agonists, lcsh:QH301-705.5, Spectroscopy, MPTP, substantia nigra pars compacta (SNpc), memory extinction, Parkinson Disease, General Medicine, Fear, CREB-Binding Protein, humanities, Computer Science Applications, Substantia Nigra, cardiovascular system, medicine.drug, Serotonergic Neurons, Substantia nigra, Serotonergic, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Memory, Animals, Physical and Theoretical Chemistry, Molecular Biology, business.industry, Pars compacta, Dentate gyrus, Dopaminergic Neurons, Organic Chemistry, nervous system diseases, Mice, Inbred C57BL, median raphe nucleus (MnRN), Disease Models, Animal, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, chemistry, nervous system, Parkinson’s disease, reticular part of the substantia nigra (SNr), Raphe Nuclei, Receptors, Serotonin, 5-HT4, business, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f474eae8bd3b6e8b11f222fdce02a826Test
http://europepmc.org/articles/PMC6862438Test

المؤلفون: Arambakkam Janardhanam Vanisree, Margabandhu Gopi

المصدر: IBRO Reports
IBRO Reports, Vol 3, Iss C, Pp 1-8 (2017)

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, PtdIns(3,4,5)P3, Phosphatidylinositol 3,4,5-trisphosphate, PC, Phosphatidyl choline, NM, Neuromelanin, Striatum, PE, Phosphatidyl ethanolamine, Pharmacology, PD, Parkinson's disease, chemistry.chemical_compound, 0302 clinical medicine, TB, Toluidine blue dye, TBAHS, tetrabutyl ammonium hydrogen sulphate, MRM, Multiple reaction monitor, ANSA, 1 Amino-2 naphthol-4 sulfonic acid, Phospholipids, PtdIns(4,5)P2, Phosphatidylinositol 4,5-bisphosphate, General Neuroscience, Parkinsonism, Dopaminergic, Biochemistry, AD, Alzheimer's disease, NaCl, Sodium chloride, TLC, Thin layer chromatography, Substantia nigra, SM, Spingomyelin, Article, lcsh:RC321-571, 03 medical and health sciences, PI(3,5)P2, Phosphatidylinositol 3,5-bisphosphate, Rotenone, medicine, Pi, SNpc, Substantia nigra pars compacta, PtdIns5P, Phosphatidylinositol 5-phosphate, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, AFTC, Ammonium ferrothiocyanate, MS, Mass spectrometry, ROT, Rotenone, DA, Dopaminergic neuron, TEM, Transmission electron microscopy, DMSO, Dimethyl sulfoxide, Metabolism, medicine.disease, VBB, Victoria blue-B dye, HCl, Hydrochloric acid, 030104 developmental biology, chemistry, ESI, Electrospray ionization, Na.EDTA, Sodium Ethylenediaminetetraacetic acid, HRLCMS, High resolution liquid chromatography–mass spectrometry, PI, Phosphoinositide, PLs, Phospholipids, 030217 neurology & neurosurgery, Dye-lipid complex

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bff7286cc0964453a641f79e008bc0eTest
https://doi.org/10.1016/j.ibror.2017.06.001Test

المؤلفون: Liyan Hou, Wei Sun, Fuqiang Sun, Ruixue Huang, Dan Zhang, Qingshan Wang

المصدر: Redox Biology, Vol 22, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, Male, Parkinson's disease, Nonmotor symptoms, Clinical Biochemistry, MPO, myeloperoxidase, Pharmacology, medicine.disease_cause, Biochemistry, PD, Parkinson's disease, Hippocampus, P + M, paraquat and maneb, chemistry.chemical_compound, Mice, 0302 clinical medicine, Paraquat, Neuroinflammation, Enzyme Inhibitors, lcsh:QH301-705.5, Cerebral Cortex, lcsh:R5-920, NADPH oxidase, biology, Behavior, Animal, Cognitive deficits, Neurodegeneration, NF-kappa B, Parkinson Disease, SNpc, substantia nigra pars compacta, Mitochondria, TNFα, tumor necrosis factor α, STAT1 Transcription Factor, MWM, morris maze test, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, Microglia, lcsh:Medicine (General), STAT1, signal transducers and activators of transcription 1, Research Paper, inorganic chemicals, TH, tyrosine hydroxylase, Iba-1, ionized calcium binding adaptor molecule-1, NF-κB, nuclear factor-κB, 03 medical and health sciences, ROS, reactive oxygen species, Memory, SOD, superoxide dismutase, medicine, Animals, Learning, MDA, malondialdehyde, Tyrosine hydroxylase, AD, Alzheimer disease, Dopaminergic Neurons, Organic Chemistry, Acetophenones, NADPH Oxidases, medicine.disease, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, chemistry, lcsh:Biology (General), Apocynin, biology.protein, Reactive Oxygen Species, 030217 neurology & neurosurgery, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0d2a312a701be8ce2761d13e178115Test
http://www.sciencedirect.com/science/article/pii/S2213231719300291Test

المؤلفون: Paul C. Keane, Christopher Morris, P.J. Kahle, Peter S. Hanson, Fiona E. N. LeBeau, Ahmad Khundakar, Peter G. Blain, Sarah J. Judge, Philippa D. Hepplewhite, Lina Patterson

المصدر: Neuroscience letters 711, 134437 (2019). doi:10.1016/j.neulet.2019.134437
Neuroscience Letters

مصطلحات موضوعية: 0301 basic medicine, Male, Parkinson's disease, pathology [Dopaminergic Neurons], drug effects [Dopaminergic Neurons], toxicity [Trichloroethylene], TaClo, pathology [Parkinsonian Disorders], toxicity [Neurotoxins], CE, coefficient of error, Mice, 0302 clinical medicine, TaClo, 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline, Neurotoxin, ANOVA, analysis of variance, α-Synuclein, Chemistry, General Neuroscience, Neurodegeneration, Dopaminergic, DA, dopaminergic, pathology [Nerve Degeneration], SNpc, substantia nigra pars compacta, Substantia Nigra, alpha-Synuclein, metabolism [Neurotoxins], genetics [alpha-Synuclein], MPTP, 1-methy,4-phenyl, 1,2,3,6 tetrahyrdopyridine, Female, Genetically modified mouse, medicine.medical_specialty, DMSO, dimethylsulfoxide, TH, tyrosine hydroxylase, Neurotoxins, Substantia nigra, Mice, Transgenic, Article, 03 medical and health sciences, Parkinsonian Disorders, Internal medicine, medicine, TCE, trichloroethylene, Animals, Humans, metabolism [Trichloroethylene], ddc:610, pathology [Substantia Nigra], PD, Parkinson’s disease, Pars compacta, Dopaminergic Neurons, Wild type, medicine.disease, nervous system diseases, Trichloroethylene, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, nervous system, Nerve Degeneration, Mutation, Parkinson’s disease, drug effects [Substantia Nigra], 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c72fc6dc3fd8505e5e8d6afd86da507Test

المؤلفون: Peter Redgrave, Eleanor J. Dommett, Véronique Coizet, Esther Marije Klop, Paul G. Overton

المساهمون: Savasta, Marc, Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Psychology [Sheffield], University of Sheffield [Sheffield], School of Life, Health and Chemical Sciences [Milton Keynes], Faculty of Science, Technology, Engineering and Mathematics [Milton Keynes], The Open University [Milton Keynes] (OU)-The Open University [Milton Keynes] (OU), Department of Neuroscience, University of Groningen [Groningen]-University Medical Centre - Anatomy Section, Wellcome Trust GR068021 Biotechnology and Biological Sciences Research Council BB/D019648/1 University of Sheffield Netherlands Organisation for Scientific Research

المصدر: Neuroscience
Neuroscience, Elsevier-International Brain Research Organization, 2010, 168 (1), pp.263-72. ⟨10.1016/j.neuroscience.2010.03.049⟩
Coizet, V, Dommett, E J, Klop, E M, Redgrave, P & Overton, P G 2010, ' The parabrachial nucleus is a critical link in the transmission of short latency nociceptive information to midbrain dopaminergic neurons ', Neuroscience, vol. 168, no. 1, pp. 263-272 . https://doi.org/10.1016/j.neuroscience.2010.03.049Test
Neuroscience, 168(1), 263-272. PERGAMON-ELSEVIER SCIENCE LTD

مصطلحات موضوعية: Male, NHS, normal horse serum, Dopamine, TX, Triton X 100, PB, phosphate buffer, PPTg, pedunculoponting tegmental nucleus, MESH: Neurons, Reticular formation, 0302 clinical medicine, Mesencephalon, Pons, RETICULAR-FORMATION, rat, MESH: Animals, nociception, Anesthetics, Local, MESH: GABA-A Receptor Antagonists, ANOVA, analysis of variance, Neurons, GLUTAMATERGIC NEURONS, 0303 health sciences, SUBSTANTIA-NIGRA, MESH: Electrophysiology, Chemistry, Muscimol, General Neuroscience, Dopaminergic, PHA-L, Phaseolus vulgaris leukoagglutinin, DA, dopaminergic, DORSAL-HORN NEURONS, MESH: Electric Stimulation, FOS-LIKE PROTEIN, PBN, parabrachial nucleus, Ventral tegmental area, Electrophysiology, Substantia Nigra, medicine.anatomical_structure, extracellular recording, LATERAL HABENULA, Female, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], MESH: Pain, SUPERIOR COLLICULUS, Research Paper, medicine.drug, LAMINA-I NEURONS, MESH: Rats, Neuroscience(all), TH, tyrosine hydroxylase, MESH: Substantia Nigra, Pain, Substantia nigra, MESH: Dopamine, VTA, ventral tegmental area, MESH: Anesthetics, Local, DAB, diaminobenzidine, 03 medical and health sciences, FLI, fos-like immunoreactivity, PBS, phosphate buffered saline, PSTH, peri-stimulus time interval histogram, medicine, Animals, GABA-A Receptor Antagonists, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], tract tracing, 030304 developmental biology, Parabrachial Nucleus, Pars compacta, SNPr, substantia nigra pars reticulata, NIGRA PARS COMPACTA, Lidocaine, MESH: Pons, Pain Mechanisms and Sensory Neuroscience, MESH: Mesencephalon, BDA, biotinylated dextran amine, Electric Stimulation, MESH: Male, Rats, VENTRAL TEGMENTAL AREA, MESH: Lidocaine, nervous system, RMTg, rostromedial tegmental nucleus, SNPc, substantia nigra pars compacta, BSA, bovine serum albumin, SD, standard deviation, Neuroscience, MESH: Female, 030217 neurology & neurosurgery, MESH: Muscimol

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b120cb1749301d1a3be1ccd2253e2b8Test
https://doi.org/10.1016/j.neuroscience.2010.03.049Test