المؤلفون: Sithara Wanni Arachchige Dona, Martin Hensher, Anna Peeters, Mary Lou Chatterton, Mary Rose Angeles, Paul Cooper, Dieu Nguyen, Natalie Heynsbergh

المصدر: Journal of the American Medical Informatics Association : JAMIA

مصطلحات موضوعية: Structure (mathematical logic), scoring and scaling, evaluation framework, 020205 medical informatics, AcademicSubjects/SCI01060, Computer science, Reviews, Health Informatics, 02 engineering and technology, Variance (accounting), health apps, assessment criteria, Summary statistics, Data science, Filter (software), Likert scale, 03 medical and health sciences, 0302 clinical medicine, Search terms, Summative assessment, Evaluation methods, 0202 electrical engineering, electronic engineering, information engineering, 030212 general & internal medicine, AcademicSubjects/SCI01530, AcademicSubjects/MED00580

الوصف: Objective The study sought to review the different assessment items that have been used within existing health app evaluation frameworks aimed at individual, clinician, or organizational users, and to analyze the scoring and evaluation methods used in these frameworks. Materials and Methods We searched multiple bibliographic databases and conducted backward searches of reference lists, using search terms that were synonyms of “health apps,” “evaluation,” and “frameworks.” The review covered publications from 2011 to April 2020. Studies on health app evaluation frameworks and studies that elaborated on the scaling and scoring mechanisms applied in such frameworks were included. Results Ten common domains were identified across general health app evaluation frameworks. A list of 430 assessment criteria was compiled across 97 identified studies. The most frequently used scaling mechanism was a 5-point Likert scale. Most studies have adopted summary statistics to generate the total scoring of each app, and the most popular approach taken was the calculation of mean or average scores. Other frameworks did not use any scaling or scoring mechanism and adopted criteria-based, pictorial, or descriptive approaches, or “threshold” filter. Discussion There is wide variance in the approaches to evaluating health apps within published frameworks, and this variance leads to ongoing uncertainty in how to evaluate health apps. Conclusions A new evaluation framework is needed that can integrate the full range of evaluative criteria within one structure, and provide summative guidance on health app rating, to support individual app users, clinicians, and health organizations in choosing or recommending the best health app.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deabc78e51dc48f73b414943e91f2fcaTest
http://europepmc.org/articles/PMC8263081Test

المؤلفون: Dylan Wills, Paul Cooper, Ioannis Karpouzis, Ben O’Brien, Neil Roberts, Martina Buerge, Damian Balmforth, Rosalie Magboo

المصدر: Journal of Cardiothoracic and Vascular Anesthesia. 34:2913-2920

مصطلحات موضوعية: medicine.medical_specialty, Psychological intervention, Audit, 030204 cardiovascular system & hematology, Single Center, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, 030202 anesthesiology, Multidisciplinary approach, Atrial Fibrillation, medicine, Humans, Cardiac Surgical Procedures, Coronary Artery Bypass, Aged, Retrospective Studies, business.industry, Incidence (epidemiology), Atrial fibrillation, Perioperative, medicine.disease, Cardiac surgery, Anesthesiology and Pain Medicine, Emergency medicine, Cardiology and Cardiovascular Medicine, business

الوصف: The authors aimed to adapt a practice advisory for the prevention of atrial fibrillation after cardiac surgery (AFACS) recently published in this journal into the authors' local perioperative protocols, implementing the recommendations, with a focus on early postoperative (re)introduction of β-blockers and overcoming frequent guideline implementation barriers.Development of a prevention care bundle and repeated audit after a model of improvement approach with retrospective analysis.Single center (tertiary academic hospital).A total of 384 patients in 2 cohorts of consecutive patients undergoing open cardiac surgery before and after hospital-wide implementation of a care bundle.After auditing the standard of care in the authors' center, an AFACS prevention care bundle was designed and implemented, consisting of a graphic tool with 5 pillars based on current evidence for the early postoperative phase. Multidisciplinary teaching and training of staff were delivered, and a second audit was conducted after the implementation period.Significantly more patients received postoperative β-blockers after care bundle implementation (82.7% pre- v 91.3% post-bundle, p = 0.019), with a higher proportion on day 1 (36.7% pre- v 67% post-bundle, p0.001), indicating a successful uptake. The incidence of AFACS was significantly reduced from 35.4% to 23.3% (p = 0.009), with a particularly marked reduction in the age group 65- to 75- years and for isolated aortic valve and coronary artery bypass graft surgery.An AFACS prevention care bundle improved adherence to current guidelines with regard to early β-blocker administration and significantly reduced the incidence of atrial fibrillation after cardiac surgery.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7c3254e51fc896049ae8b63d3fe240Test
https://doi.org/10.1053/j.jvca.2020.06.078Test

المؤلفون: Su Qiong Xu, Paul Cooper

المصدر: International Journal of Inclusive Education. 26:815-833

مصطلحات موضوعية: Mainland China, 030506 rehabilitation, media_common.quotation_subject, 05 social sciences, Individual difference, 050301 education, General education, Education, 03 medical and health sciences, Arts and Humanities (miscellaneous), Perception, Pedagogy, ComputingMilieux_COMPUTERSANDEDUCATION, Mainstream, Sociology, 0305 other medical science, China, 0503 education, media_common

الوصف: This paper explores how mainstream teachers, in mainland China with experience of inclusive education, perceive individual differences (ID) among students in general education classrooms. The study...

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::63216797b559dcac43e28e306f326774Test
https://doi.org/10.1080/13603116.2020.1735541Test

المؤلفون: Éva Monostori, Éva Kriston-Pál, Valeria Szukacsov, Endre Kiss-Toth, Lajos Haracska, Paul Cooper

المصدر: Frontiers in Veterinary Science
Frontiers in Veterinary Science, Vol 7 (2020)

مصطلحات موضوعية: dogs, medicine.medical_specialty, 040301 veterinary sciences, Adipose tissue, long-term follow-up, Osteoarthritis, 0403 veterinary science, Cell therapy, 03 medical and health sciences, Internal medicine, medicine, mesenchymal stem cell, 030304 developmental biology, Cause of death, therapy, 0303 health sciences, lcsh:Veterinary medicine, General Veterinary, business.industry, Mesenchymal stem cell, safety of therapy, Cancer, 04 agricultural and veterinary sciences, Brief Research Report, medicine.disease, Transplantation, osteoarthritis, Lameness, lcsh:SF600-1100, Veterinary Science, business

الوصف: Mesenchymal stem cells (MSC) are emerging as an effective therapeutic tool in treating canine osteoarthritis (OA). In this report, we focused on the questions of whether MSC transplantation has long-term beneficial effects for the improvement in motion and also evaluated the safety of MSC injection. Visceral adipose tissue, a surgical waste obtained during routine ovariectomy served as a source of allogeneic MSCs and used to treat OA. Altogether, fifty-eight dogs were transplanted in the study suffering from OA in the elbow (42 animals), hip (5), knee (8), ankle (2), and hock (1). The effect of MSC transplantation was evaluated by the degree of lameness at a 4-5-years follow-up period based on the owners' subjective observations. The results showed that 83% of the OA patients improved or retained improvement in lameness. Clinical safety of the treatment was assessed by evaluating the coincidence of tumors or other diseases and other adverse reactions (such as local inflammation) after MSC cell therapy. Two incidences of local inflammation for

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الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c715c4e3d138cdb3e5be146d07345b3bTest
https://doi.org/10.3389/fvets.2020.00510Test

المؤلفون: Kirsty J Martin-McGill, Robert G Levy, Paul Cooper, Rebecca Bresnahan

المصدر: Cochrane Database Syst Rev
Cochrane Database of Systematic Reviews

مصطلحات موضوعية: 0301 basic medicine, Adult, Pediatrics, medicine.medical_specialty, Drug Resistant Epilepsy, Adolescent, medicine.medical_treatment, food.diet, Population, 03 medical and health sciences, Epilepsy, Diet, Carbohydrate-Restricted, Young Adult, 0302 clinical medicine, food, Weight loss, Dietary Carbohydrates, Medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Prospective Studies, education, Child, Aged, Randomized Controlled Trials as Topic, Retrospective Studies, education.field_of_study, Atkins diet, Intention-to-treat analysis, business.industry, Age Factors, Infant, Middle Aged, medicine.disease, Dietary Fats, Intention to Treat Analysis, 030104 developmental biology, Meta-analysis, Child, Preschool, Sample Size, Quality of Life, medicine.symptom, business, Diet, Ketogenic, 030217 neurology & neurosurgery, Diet, High-Protein Low-Carbohydrate, Ketogenic diet

الوصف: BACKGROUND: Ketogenic diets (KDs) are high in fat and low in carbohydrates and have been suggested to reduce seizure frequency in people with epilepsy. Such diets may be beneficial for children with drug‐resistant epilepsy. This is an update of a review first published in 2003, and last updated in 2018. OBJECTIVES: To assess the effects of ketogenic diets for people with drug‐resistant epilepsy. SEARCH METHODS: For this update, we searched the Cochrane Register of Studies (CRS Web) and MEDLINE (Ovid, 1946 to 26 April 2019) on 29 April 2019. The Cochrane Register of Studies includes the Cochrane Epilepsy Group Specialized Register, the Cochrane Central Register of Controlled Trials (CENTRAL), and randomised controlled trials (RCTs) from Embase, ClinicalTrials.gov and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP). We imposed no language restrictions. We checked the reference lists of retrieved studies for additional relevant studies. SELECTION CRITERIA: RCTs or quasi‐RCTs of KDs for people of any age with drug‐resistant epilepsy. DATA COLLECTION AND ANALYSIS: Two review authors independently applied predefined criteria to extract data and evaluated study quality. We assessed the outcomes: seizure freedom, seizure reduction (50% or greater reduction in seizure frequency), adverse effects, cognition and behaviour, quality of life, and attrition rate. We incorporated a meta‐analysis. We utilised an intention‐to‐treat (ITT) population for all primary analyses. We presented the results as risk ratios (RRs) with 95% confidence intervals (CIs). MAIN RESULTS: We identified 13 studies with 932 participants; 711 children (4 months to 18 years) and 221 adults (16 years and over). We assessed all 13 studies to be at high risk of performance and detection bias, due to lack of blinding. Assessments varied from low to high risk of bias for all other domains. We rated the evidence for all outcomes as low to very low certainty. Ketogenic diets versus usual care for children Seizure freedom (RR 3.16, 95% CI 1.20 to 8.35; P = 0.02; 4 studies, 385 participants; very low‐certainty evidence) and seizure reduction (RR 5.80, 95% CI 3.48 to 9.65; P < 0.001; 4 studies, 385 participants; low‐certainty evidence) favoured KDs (including: classic KD, medium‐chain triglyceride (MCT) KD combined, MCT KD only, simplified modified Atkins diet (MAD) compared to usual care for children. We are not confident that these estimated effects are accurate. The most commonly reported adverse effects were vomiting, constipation and diarrhoea for both the intervention and usual care group, but the true effect could be substantially different (low‐certainty evidence). Ketogenic diet versus usual care for adults In adults, no participants experienced seizure freedom. Seizure reduction favoured KDs (MAD only) over usual care but, again, we are not confident that the effect estimated is accurate (RR 5.03, 95% CI 0.26 to 97.68; P = 0.29; 2 studies, 141 participants; very low‐certainty evidence). Adults receiving MAD most commonly reported vomiting, constipation and diarrhoea (very low‐certainty evidence). One study reported a reduction in body mass index (BMI) plus increased cholesterol in the MAD group. The other reported weight loss. The true effect could be substantially different to that reported. Ketogenic diet versus ketogenic diet for children Up to 55% of children achieved seizure freedom with a classical 4:1 KD after three months whilst up to 85% of children achieved seizure reduction (very low‐certainty evidence). One trial reported a greater incidence of seizure reduction with gradual‐onset KD, as opposed to fasting‐onset KD. Up to 25% of children were seizure free with MAD and up to 60% achieved seizure reduction. Up to 25% of children became seizure free with MAD and up to 60% experienced seizure reduction. One study used a simplified MAD (sMAD) and reported that 15% of children gained seizure freedom rates and 56% achieved seizure reduction. We judged all the evidence described as very low certainty, thus we are very unsure whether the results are accurate. The most commonly reported adverse effects were vomiting, constipation and diarrhoea (5 studies, very low‐certainty evidence). Two studies reported weight loss. One stated that weight loss and gastrointestinal disturbances were more frequent, with 4:1 versus 3:1 KD, whilst one reported no difference in weight loss with 20 mg/d versus 10 mg/d carbohydrates. In one study, there was a higher incidence of hypercalcuria amongst children receiving classic KD compared to MAD. All effects described are unlikely to be accurate. Ketogenic diet versus ketogenic diet for adults One study randomised 80 adults (aged 18 years and over) to either MAD plus KetoCal during the first month with MAD alone for the second month, or MAD alone for the first month followed by MAD plus KetoCal for the second month. No adults achieved seizure freedom. More adults achieved seizure reduction at one month with MAD alone (42.5%) compared to MAD plus KetoCal (32.5%), however, by three months only 10% of adults in both groups maintained seizure reduction. The evidence for both outcomes was of very low certainty; we are very uncertain whether the effects are accurate. Constipation was more frequently reported in the MAD plus KetoCal group (17.5%) compared to the MAD only group (5%) (1 study, very low‐certainty evidence). Diarrhoea and increase/change in seizure pattern/semiology were also commonly reported (17.5% to 20% of participants). The true effects of the diets could be substantially different to that reported. AUTHORS' CONCLUSIONS: The evidence suggests that KDs could demonstrate effectiveness in children with drug‐resistant epilepsy, however, the evidence for the use of KDs in adults remains uncertain. We identified a limited number of studies which all had small sample sizes. Due to the associated risk of bias and imprecision caused by small study populations, the evidence for the use of KDs was of low to very low certainty. More palatable but related diets, such as the MAD, may have a similar effect on seizure control as the classical KD, but could be associated with fewer adverse effects. This assumption requires more investigation. For people who have drug‐resistant epilepsy or who are unsuitable for surgical intervention, KDs remain a valid option. Further research is required, particularly for adults with drug‐resistant epilepsy.

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الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cd1409325f653b9952aad9c231a01bTest
https://pubmed.ncbi.nlm.nih.gov/33929168Test

المؤلفون: William M. Palin, Paul Cooper, Beryl Oppenheim, Mohammed A. Hadis, Michael R. Milward, Fenella D. Halstead, Kristian Brock, N Marley

المصدر: Applied and Environmental Microbiology

مصطلحات موضوعية: Acinetobacter baumannii, Staphylococcus aureus, Light, medicine.disease_cause, Applied Microbiology and Biotechnology, 03 medical and health sciences, Escherichia coli, medicine, Biomass, Irradiation, 030304 developmental biology, Cross Infection, 0303 health sciences, Bacteria, Ecology, biology, Public and Environmental Health Microbiology, 030306 microbiology, Pseudomonas aeruginosa, Chemistry, Biofilm, decontamination, Antimicrobial, biology.organism_classification, Anti-Bacterial Agents, Biofilms, Biophysics, wound decontamination, photodisinfection, Antibacterial activity, phototherapy, Food Science, Biotechnology

الوصف: This study reports the efficacy of VBL and blue light (BL) and their antimicrobial activity against mature biofilms of a range of important nosocomial pathogens. While this study investigated the antibacterial activity of a range of wavelengths of between 375 and 450 nm and identified a specific wavelength region (∼405 nm) with increased antibacterial activity, decontamination was dependent on the bacterial species, strain, irradiation parameters, and experimental conditions. Further research with controlled experiments that ameliorate the heating effects and improve the optical properties are required to optimize the dosing parameters to advance the successful clinical translation of this technology.
Light-emitting diodes (LEDs) demonstrate therapeutic effects for a range of biomedical applications, including photodisinfection. Bands of specific wavelengths (centered at 405 nm) are reported to be the most antimicrobial; however, there remains no consensus on the most effective irradiation parameters for optimal photodisinfection. The aim of this study was to assess decontamination efficiency by direct photodisinfection of monomicrobial biofilms using a violet-blue light (VBL) single-wavelength array (SWA) and multiwavelength array (MWA). Mature biofilms of nosocomial bacteria (Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus) were grown on 96-well polypropylene PCR plates. The biofilms were then exposed to VBL for 2,700 s (SWA) and 1,170 s (MWA) to deliver 0 to 670 J/cm2, and the antibacterial activity of VBL was assessed by comparing the seeding of the irradiated and the nonirradiated biofilms. Nonirradiated groups were used as controls. The VBL arrays were characterized optically (spectral irradiance and beam profile) and thermally. The SWA delivered 401-nm VBL and the MWA delivered between 379-nm and 452-nm VBL, albeit at different irradiances and with different beam profiles. In both arrays, the irradiated groups were exposed to increased temperatures compared to the nonirradiated controls. All bacterial isolates were susceptible to VBL and demonstrated reductions in the seeding of exposed biofilms compared with the nonirradiated controls. VBL at 405 nm exerted the most antimicrobial activity, exhibiting reductions in seeding of up to 94%. Decontamination efficiency is dependent on the irradiation parameters, bacterial species and strain, and experimental conditions. Controlled experiments that ameliorate the heating effects and improve the optical properties are required to optimize the dosing parameters to advance the successful clinical translation of this technology. IMPORTANCE This study reports the efficacy of VBL and blue light (BL) and their antimicrobial activity against mature biofilms of a range of important nosocomial pathogens. While this study investigated the antibacterial activity of a range of wavelengths of between 375 and 450 nm and identified a specific wavelength region (∼405 nm) with increased antibacterial activity, decontamination was dependent on the bacterial species, strain, irradiation parameters, and experimental conditions. Further research with controlled experiments that ameliorate the heating effects and improve the optical properties are required to optimize the dosing parameters to advance the successful clinical translation of this technology.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98f0d936988acd2f04b1187b686f2d0Test
https://doi.org/10.1128/aem.01346-19Test

المؤلفون: Michael Quintel, Theresia Pellio, Mathieu Monnheimer, Uwe Groß, Marco H. Schulze, Iryna Janssen, Clemens Kainyah, Paul Cooper, Hauke Janssen

المصدر: Emerging Infectious Diseases

مصطلحات موضوعية: polymicrobial infections, 0301 basic medicine, Microbiology (medical), Gram-negative bacteria, Microbiological culture, Antimicrobial resistant bacteria, Epidemiology, medicine.drug_class, 030106 microbiology, 030231 tropical medicine, Cephalosporin, MRSA, medicine.disease_cause, Ghana, Microbiology, resistance, 03 medical and health sciences, 0302 clinical medicine, Antibiotic resistance, Enterobacteriaceae, Drug Resistance, Bacterial, medicine, Humans, AMR, antimicrobial resistance, Bacteria, biology, multiresistant, business.industry, Dispatch, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, biology.organism_classification, gram-negative bacteria, Antimicrobial-Resistant Bacteria in Infected Wounds, Ghana, 2014, Anti-Bacterial Agents, wound infections, Infectious Diseases, Staphylococcus aureus, Wound Infection, rural, business

الوصف: Wound infections are an emerging medical problem worldwide, frequently neglected in under-resourced countries. Bacterial culture and antimicrobial drug resistance testing of infected wounds in patients in a rural hospital in Ghana identified no methicillin-resistant Staphylococcus aureus or carbapenem-resistant Enterobacteriaceae but identified high combined resistance of Enterobacteriaceae against third-generation cephalosporins and fluoroquinolones.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0928ee074e240d6ed11bdd6b9419291aTest
https://doi.org/10.3201/eid2405.171506Test

المؤلفون: Shungo Komichi, Motoki Okamoto, Masakatsu Watanabe, Takeo Nakai, Mikako Hayashi, Manahil Ali, Paul Cooper, Hailing Huang, Yusuke Takahashi

المصدر: Cells
Cells, Vol 8, Iss 9, p 1002 (2019)
Volume 8
Issue 9

مصطلحات موضوعية: 0301 basic medicine, Male, Matrix metalloproteinase, Article, Dental Pulp Capping, S100 Calcium Binding Protein A7, 03 medical and health sciences, 0302 clinical medicine, proteomics, stomatognathic system, Glycation, Dentin, medicine, Animals, Humans, Dental Pulp Exposure, Rats, Wistar, lcsh:QH301-705.5, Dental Pulp, Wound Healing, Chemistry, pulp capping materials, 030206 dentistry, General Medicine, Dentinogenesis, Cell biology, Pulp capping, Rats, stomatognathic diseases, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), Pulp (tooth), Stem cell, Wound healing

الوصف: Dentin consists of inorganic hard tissue and organic dentin matrix components (DMCs). Various kinds of bioactive molecules are included in DMCs and some of them can be released after digestion by endogenous matrix metalloproteinases (MMPs) in the caries region. Digested DMCs induced by MMP20 have been reported to promote pulpal wound healing processes, but the released critical molecules responsible for this phenomenon are unclear. Here, we identified protein S100-A7 as a critical molecule for pulpal healing in digested DMCs by comprehensive proteomic approaches and following pulp capping experiments in rat molars. In addition, immunohistochemical results indicated the specific distribution of S100-A7 and receptor for advanced glycation end-products (RAGE) as receptor for S100-A7 in the early stage of the pulpal healing process, and following accumulation of CD146-positive stem cells in wounded pulp. Our findings indicate that protein S100-A7 released from dentin by MMP20 might play a key role in dentin pulp regeneration.

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الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d90a78733bea0cd9e99733b975eb10fTest
http://europepmc.org/articles/PMC6769619Test

المؤلفون: Oliver Bader, Raimond Lugert, Fabian M. Völker, A. Uy, Ortrud Zimmermann, Paul Cooper, Uwe Groß

المصدر: BMC Pregnancy and Childbirth, Vol 17, Iss 1, Pp 1-7 (2017)
BMC Pregnancy and Childbirth

مصطلحات موضوعية: Rural Population, Herpesvirus 3, Human, Prevalence, Cytomegalovirus, Pilot Projects, Ghana, 0302 clinical medicine, Risk Factors, Seroepidemiologic Studies, Pregnancy, Parvovirus B19, Human, 030212 general & internal medicine, Pregnancy Complications, Infectious, Obstetrics, 1. No poverty, Obstetrics and Gynecology, Hepatitis C, Middle Aged, Hepatitis B, 3. Good health, Group B streptococci, Female, Toxoplasma, Research Article, Adult, medicine.medical_specialty, Adolescent, Listeria, 030231 tropical medicine, Infections, Rubella, lcsh:Gynecology and obstetrics, Young Adult, 03 medical and health sciences, Streptococcal Infections, medicine, Humans, Treponema pallidum, lcsh:RG1-991, Hepatitis, business.industry, medicine.disease, Brucella, Neisseria gonorrhoeae, Malaria, Cross-Sectional Studies, Immunoglobulin G, Immunology, Syphilis, business, Rubella virus

الوصف: Background Although infectious diseases still account for a high burden of morbidity and mortality in sub-Saharan Africa, simultaneous investigations on multiple infections affecting maternal and child health are missing. Methods We conducted a cross-sectional, single-centre pilot study in a rural area of Ghana to assess the infectiological profile during pregnancy. Screening of 180 expectant mothers was done by vaginal swabs and serology to detect the most common pregnancy-relevant infections. They were also interviewed for potential risk factors, outcome of previous pregnancies, and socio-economic aspects. Results We found a high prevalence of infections caused by hepatitis B virus (16.7% HBs antigen positive). In contrast, infections caused by hepatitis C virus (1.1% anti-HCV) and HIV (0.6%) were rare. Maternal malaria was frequent (10.6%), despite increasing acceptance of intermittent preventive treatment during pregnancy (IPTp). Group B streptococci were present in 10.6% of all pregnant women. Absence of antibodies against varicella zoster virus in 43.2%, Toxoplasma gondii in 26.8%, parvovirus B19 in 20.0%, and rubella virus in 15.7% makes a significant proportion of pregnant women susceptible for acquiring primary infections. Whereas all study participants had specific IgG antibodies against human cytomegalovirus, infections with Listeria, Brucella, or Neisseria gonorrhoeae as well as active syphilis were absent. Conclusions Our pilot study in a rural community in Ghana indicates an urgent need for action in dealing at least with high-prevalent pregnancy-relevant infections, such as hepatitis B, malaria and those caused by group B streptococci. In addition, the resulting prevalence rates of various other infections may offer guidance for health officials to prioritize possible future intervention schemes. Electronic supplementary material The online version of this article (doi:10.1186/s12884-017-1351-3) contains supplementary material, which is available to authorized users.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5897de59c9d719285c1914c796d4bbaTest
http://link.springer.com/article/10.1186/s12884-017-1351-3Test

المؤلفون: Maria S. Poulou, Paul Cooper

المصدر: British Journal of Special Education. 44:65-94

مصطلحات موضوعية: Biopsychosocial model, media_common.quotation_subject, 05 social sciences, Strengths and Difficulties Questionnaire, Sleep in non-human animals, Differential effects, Education, Developmental psychology, Sleep patterns, 03 medical and health sciences, 0302 clinical medicine, Consistency (negotiation), Perception, Developmental and Educational Psychology, 0501 psychology and cognitive sciences, Psychology, 030217 neurology & neurosurgery, 050104 developmental & child psychology, Sleep duration, media_common

الوصف: The study investigated adolescent students’ perceptions of sleep duration and patterns, and the way they relate to emotional and behavioural difficulties. Five hundred and two students from public schools in Greece completed the Sleep Questionnaire and the Strengths and Difficulties Questionnaire (SDQ). It was demonstrated that consistency in sleep duration and quality in sleep patterns were associated with a reduction in adolescents’ reports of emotional and behavioural difficulties. Sleep duration was similarly distributed across gender, while sleep patterns were gender-specific. Distinct differential effects of gender, sleep duration and patterns to adolescents’ emotional and behavioural difficulties were also found. These findings and their implications for research and practice are discussed, within the scope of the biopsychosocial framework in education.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2e0721725f6624c7aa1fa42fae4fa4c3Test
https://doi.org/10.1111/1467-8578.12161Test