يعرض 1 - 10 نتائج من 62 نتيجة بحث عن '"NASH non-alcoholic steatohepatitis"', وقت الاستعلام: 1.61s تنقيح النتائج
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    المصدر: Journal of Clinical and Experimental Hepatology

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    المصدر: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 19, iss 8
    Clinical Gastroenterology and Hepatology

    مصطلحات موضوعية: PD-L1, programmed death ligand 1, medicine.medical_treatment, Liver transplantation, Systemic therapy, 0302 clinical medicine, Model for End-Stage Liver Disease, Pandemic, alpha-fetoprotein (AFP), HCC, CMS, Centers for Medicare and Medicaid services, Cancer, COVID-19, Coronavirus disease 2019, AFP, alpha-fetoprotein, Liver Disease, Liver Neoplasms, BCLC, Barcelona Clinic Liver Cancer, Gastroenterology, RETREAT, Risk estimation of tumor recurrence after liver transplantation, LRT, local regional therapy, VEGF, vascular endothelial growth factor, Local, HCV, hepatitis C virus, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Screening, 030211 gastroenterology & hepatology, alpha-Fetoproteins, Patient Safety, Alpha-Fetoprotein, Liver Cancer, medicine.medical_specialty, Carcinoma, Hepatocellular, CTP, Child-Turcotte-Pugh, NASH, non-alcoholic steatohepatitis, AFP, Clinical Sciences, Context (language use), LT, liver transplantation, Lower risk, Article, 03 medical and health sciences, Rare Diseases, SBRT, stereotactic body radiotherapy, Clinical Research, GALAD, gender, age, AFP-L3, AFP, and DCP, medicine, AFP-L3, lectin-reactive alpha-fetoprotein, Humans, DCP, des-gamma carboxyprothrombin, Intensive care medicine, Adverse effect, Pandemics, RCT, randomized control trial, UNOS, United Network for Organ Sharing, Gastroenterology & Hepatology, Hepatology, SARS-CoV-2, business.industry, screening, MELD, Model for End Stage Liver Disease, Prevention, Carcinoma, COVID-19, Evaluation of treatments and therapeutic interventions, Hepatocellular, medicine.disease, TACE, trans-arterial chemoembolization, Coronavirus, HBV, hepatitis B virus, Neoplasm Recurrence, Good Health and Well Being, Neoplasm Recurrence, Local, HCC, hepatocellular carcinoma, Digestive Diseases, business

    وصف الملف: application/pdf

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    المصدر: Regenerative Therapy
    Regenerative Therapy, Vol 18, Iss, Pp 97-101 (2021)

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    المؤلفون: Raluca Pais, Rachel Ostroff, Stephen Harrison, Lars Friis Mikkelsen, Elisabeth Erhardtsen, Sudha Shankar, Kimmo Porthan, Jérôme Boursier, Antonia Sinisi, Michael Kalutkiewicz, Sven Francque, Miljen Martic, Vanessa Pellegrinelli, Phil N. Newsome, Guido Hanauer, Hannele Yki-Järvinen, Rebecca Darlay, Joel Myers, Carla Yunis, Salvatore Petta, Mette Skalshøi Kjær, Pablo Ortiz, Ann K. Daly, James H. Clark, Dina Tiniakos, Yasaman Vali, Hadi Zafarmand, Matej Orešič, Maurizio Parola, Estelle Sandt, Lori L. Jennings, Matt Kelly, Tuulia Hyötyläinen, Detlef Schuppan, Céline Fournier, Chiara Rosso, Diane E. Shevell, Maria Manuela Tonini, Paul Hockings, Aidan McGlinchey, Salma Akhtar, Mette Juul Fisker, Morten A. Karsdal, Diane Whalley, Melissa R. Miller, Aldo Trylesinski, Mattias Ekstedt, Stefan Neubauer, Jeremy M. Palmer, Partho Sen, Michael Pavlides, Per Qvist, Isabel Fernández, Luca Miele, Fabio Marra, Stergios Kechagias, Richard Torstenson, Katherine Johnson, Jean-François Dufour, Elisabetta Bugianesi, M. Julia Brosnan, George V. Papatheodoridis, Kay M. Pepin, Daniel Guldager Kring Rasmussen, Henrik Landgren, Rachel Queen, Simon Cockell, Michael Allison, Patrick M.M. Bossuyt, Rocío Gallego-Durán, Christian Rosenquist, Leigh Alexander, Elizabeth Shumbayawonda, Michele Vacca, Antonio Vidal-Puig, David Wenn, Rémy Hanf, Oscar Millet, Michalina Zatorska, R. Myers, José M. Mato, Jenny Lee, Theresa Tuthill, James Twiss, Ramy Younes, Peter Leary, Lynda Doward, Kristy Wonders, Guruprasad P. Aithal, Sarah Charlton, Vlad Ratziu, Cecília M. P. Rodrigues, Christian Trautwein, Helena Cortez-Pinto, Gideon Ho, Matt J. Barter, Judith Ertle, Jörn M. Schattenberg, Maria-Magdalena Balp, Yang-Lin Liu, Clifford A. Brass, Olivier Govaere, Amalia Gastaldelli, Sergio Rodriguez Cuenca, Pierre Chaumat, Fiona Oakley, Luca Valenti, Simon J. Cockell, Saskia W.C. van Mil, Ferenc E. Mózes, Andreas Geier, Timothy Hardy, Pierre Bedossa, Andrea Dennis, Richard L. Ehman, Charlotte Erpicum, Karine Clément, Jeremy F. L. Cobbold, Christopher P. Day, Rajarshi Banerjee, Manuel Romero-Gómez, Quentin M. Anstee, Adriaan G. Holleboom, Heather J. Cordell, Kevin L. Duffin, Diana Julie Leeming

    المساهمون: Epidemiology and Data Science, APH - Methodology, APH - Personalized Medicine, Vascular Medicine, ACS - Diabetes & metabolism, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, APH - Aging & Later Life, ARD - Amsterdam Reproduction and Development, Graduate School, Investigators, LITMUS Consortium, Johnson K., Leary P.J., Govaere O., Barter M.J., Charlton S.H., Cockell S.J., Tiniakos D., Zatorska M., Bedossa P., Brosnan M.J., Cobbold J.F., Ekstedt M., Aithal G.P., Clement K., Schattenberg J.M., Boursier J., Ratziu V., Bugianesi E., Anstee Q.M., Daly A.K., Clark J., Cordell H.J., Darlay R., Day C.P., Hardy T., Liu Y.-L., Oakley F., Palmer J., Queen R., Wonders K., Bossuyt P.M., Holleboom A.G., Zafarmand H., Vali Y., Lee J., Pais R., Schuppan D., Allison M., Cuenca S.R., Pellegrinelli V., Vacca M., Vidal-Puig A., Hyotylainen T., McGlinchey A., Oresic M., Sen P., Mato J., Millet O., Dufour J.-F., Harrison S., Neubauer S., Pavlides M., Mozes F., Akhtar S., Banerjee R., Kelly M., Shumbayawonda E., Dennis A., Erpicum C., Romero-Gomez M., Gallego-Duran R., Fernandez I., Karsdal M., Leeming D., Fisker M.J., Erhardtsen E., Rasmussen D., Qvist P., Sinisi A., Sandt E., Tonini M.M., Parola M., Rosso C., Marra F., Gastaldelli A., Francque S., Kechagias S., Yki-Jarvinen H., Porthan K., van Mil S., Papatheodoridis G., Cortez-Pinto H., Valenti L., Petta S., Miele L., Geier A., Trautwein C., Hockings P., Newsome P., Wenn D., Pereira Rodrigues C.M., Hanf R., Chaumat P., Rosenquist C., Trylesinski A., Ortiz P., Duffin K., Yunis C., Miller M., Tuthill T., Ertle J., Younes R., Alexander L., Ostroff R., Kjaer M.S., Mikkelsen L.F., Brass C., Jennings L., Balp M.-M., Martic M., Hanauer G., Shankar S., Torstenson R., Fournier C., Ehman R., Kalutkiewicz M., Pepin K., Myers J., Shevell D., Ho G., Landgren H., Myers R., Doward L., Whalley D., Twiss J., Miller, Melissa, Tuthill, Theresa, Ertle, Judith, Younes, Ramy, Alexander, Leigh, Ostroff, Rachel, Kjær, Mette Skalshøi, Mikkelsen, Lars Friis, Brass, Clifford, Jennings, Lori, Balp, Maria-Magdalena, Martic, Miljen, Hanauer, Guido, Shankar, Sudha, Torstenson, Richard, Fournier, Céline, Ehman, Richard, Kalutkiewicz, Michael, Pepin, Kay, Myers, Joel, Shevell, Diane, Ho, Gideon, Landgren, Henrik, Myers, Rob, Doward, Lynda, Whalley, Diane, Twiss, James, Clark, James, Cordell, Heather J., Darlay, Rebecca, Day, Christopher P., Hardy, Tim, Liu, Yang-Lin, Oakley, Fiona, Palmer, Jeremy, Queen, Rachel, Wonders, Kristy, Bossuyt, Patrick M., Holleboom, Adriaan G., Zafarmand, Hadi, Vali, Yasaman, Lee, Jenny, Clement, Karine, Pais, Raluca, Schuppan, Detlef, Allison, Michael, Cuenca, Sergio Rodriguez, Pellegrinelli, Vanessa, Vacca, Michele, Vidal-Puig, Antonio, Hyötyläinen, Tuulia, McGlinchey, Aidan, Orešič, Matej, Sen, Partho, Mato, Jose, Millet, Óscar, Dufour, Jean-Francois, Harrison, Stephen, Neubauer, Stefan, Pavlides, Michael, Mozes, Ferenc, Akhtar, Salma, Banerjee, Rajarshi, Kelly, Matt, Shumbayawonda, Elizabeth, Dennis, Andrea, Erpicum, Charlotte, Romero-Gomez, Manuel, Gallego-Durán, Rocío, Fernández, Isabel, Karsdal, Morten, Leeming, Diana, Fisker, Mette Juul, Erhardtsen, Elisabeth, Rasmussen, Daniel, Qvist, Per, Sinisi, Antonia, Sandt, Estelle, Tonini, Maria Manuela, Parola, Maurizio, Rosso, Chiara, Marra, Fabio, Gastaldelli, Amalia, Francque, Sven, Kechagias, Stergios, Yki-Järvinen, Hannele, Porthan, Kimmo, van Mil, Saskia, Papatheodoridis, George, Cortez-Pinto, Helena, Valenti, Luca, Petta, Salvatore, Miele, Luca, Geier, Andreas, Trautwein, Christian, Hockings, Paul, Newsome, Phil, Wenn, David, Pereira Rodrigues, Cecília Maria, Hanf, Rémy, Chaumat, Pierre, Rosenquist, Christian, Trylesinski, Aldo, Ortiz, Pablo, Duffin, Kevin, Yunis, Carla

    المصدر: JHEP Reports, 4(2):100409. Elsevier
    JHEP Reports
    JHEP Reports, Vol 4, Iss 2, Pp 100409-(2022)
    JHEP reports 4(2), 100409 (2022). doi:10.1016/j.jhepr.2021.100409

    مصطلحات موضوعية: SCORING SYSTEM, CPM, counts per million, AUROC, area under the receiver operating characteristic, RC799-869, AST, aspartate aminotransferase, MicroRNA, Non-alcoholic fatty liver disease, Biomarker, Sequencing, TGF-β, transforming growth factor-beta, Gastroenterology, STEATOHEPATITIS, Liver disease, 0302 clinical medicine, Fibrosis, miRNA, microRNA, logFC, log2 fold change, FIBROSIS, Immunology and Allergy, 0303 health sciences, education.field_of_study, NAS, NAFLD activity score, medicine.diagnostic_test, Fatty liver, GTEx, Genotype-Tissue Expression, Diseases of the digestive system. Gastroenterology, 3. Good health, Real-time polymerase chain reaction, Biomarker, MicroRNA, Non-alcoholic fatty liver disease, Sequencing, Liver biopsy, ACID, Biomarker (medicine), 030211 gastroenterology & hepatology, Life Sciences & Biomedicine, Research Article, EXPRESSION, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, NASH, non-alcoholic steatohepatitis, Population, Gastroenterology and Hepatology, SAF, steatosis–activity–fibrosis, VALIDATION, ER, endoplasmic reticulum, 03 medical and health sciences, cDNA, complementary DNA, Internal medicine, ALT, alanine aminotransferase, Gastroenterologi, Internal Medicine, medicine, NAFL, non-alcoholic fatty liver, ALGORITHM, FIB-4, fibrosis-4, education, 030304 developmental biology, PCA, principal component analysis, Science & Technology, Gastroenterology & Hepatology, Hepatology, business.industry, FC, fold change, medicine.disease, digestive system diseases, FLIP, fatty liver inhibition of progression, Ct, cycle threshold, Steatosis, qPCR, quantitative PCR, business

    وصف الملف: application/pdf; Electronic-eCollection

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    المصدر: Regenerative Therapy, Vol 11, Iss, Pp 269-281 (2019)
    Regenerative Therapy

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    المساهمون: Imperial College London, King‘s College London, Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University College of London [London] (UCL), Manship, Brigitte, BRC ITMAT Funding Scheme, Medical Research Council

    المصدر: EBioMedicine
    EBioMedicine, 2019, 49, pp.258-268. ⟨10.1016/j.ebiom.2019.10.011⟩

    مصطلحات موضوعية: CHRONIC LIVER-FAILURE, 0301 basic medicine, Liver Cirrhosis, Male, Cirrhosis, Research paper, Transcription, Genetic, Apoptosis, Research & Experimental Medicine, CD8-Positive T-Lymphocytes, Chronic liver disease, Severity of Illness Index, 0302 clinical medicine, INFECTION, Ascites, Cytotoxic T cell, Myeloid Cells, CD8(+)T cells, ALD, alcohol-related liver disease, NEUTROPHILS, CD8(+) T cells, medicine.diagnostic_test, ACLF, acute-on-chronic-liver disease, General Medicine, Middle Aged, 3. Good health, CD8+T cells, Phenotype, Treatment Outcome, Medicine, Research & Experimental, 030220 oncology & carcinogenesis, SURVIVAL, CLD, Chronic liver disease, Female, Disease Susceptibility, medicine.symptom, Peritoneum, Life Sciences & Biomedicine, EXPRESSION, CAID, cirrhosis-associated immune dysfunction, NASH, non-alcoholic steatohepatitis, Cirrhosis-associated immune dysfunction, [SDV.CAN]Life Sciences [q-bio]/Cancer, AAH, acute alcoholic hepatitis, Peripheral blood mononuclear cell, General Biochemistry, Genetics and Molecular Biology, Flow cytometry, 03 medical and health sciences, Medicine, General & Internal, Immune system, [SDV.CAN] Life Sciences [q-bio]/Cancer, General & Internal Medicine, medicine, HV, Healthy volunteers, Humans, Aged, Cell Proliferation, Inflammation, Science & Technology, business.industry, ELD, End-stage-liver diseases, HLA-DR Antigens, medicine.disease, AD, acute decompensation, 030104 developmental biology, Immunology, Natural Killer T-Cells, business, CD8, Biomarkers, PMNs, polymorphonuclear neutrophils

    وصف الملف: application/pdf

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    المصدر: Molecular Metabolism, Vol 51, Iss, Pp 101235-(2021)
    Molecular Metabolism

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    المصدر: JHEP reports : innovation in hepatology, vol 3, iss 3
    JHEP Reports
    JHEP Reports, Vol 3, Iss 3, Pp 100281-(2021)

    مصطلحات موضوعية: phosphatidylinositol, Cirrhosis, Steatosis, ALT, hexosylceramide, Humanised mice, SREBP, sterol regulatory element-binding protein, PI, RC799-869, CMHs, chimeric mouse hepatocytes, 0302 clinical medicine, GGT, gamma-glutamyl transpeptidase, aspartate aminotransferase, HCC, gamma-glutamyl transpeptidase, chemistry.chemical_classification, 0303 health sciences, education.field_of_study, Western-type diet, Gastroenterology, NASH, CHHs, Diseases of the digestive system. Gastroenterology, 3. Good health, confidence transcript, HCT, cholesteryl ester, human albumin, DCER, dihydroceramide, 030211 gastroenterology & hepatology, PC, non-alcoholic steatohepatitis, PE, transgene-free Il2rg-/-/Rag2-/-/Fah, free fatty acid, LPE, lysophosphatidylethanolamine, DCER, NASH, non-alcoholic steatohepatitis, HCER, hexosylceramide, NC, normal chow, TIRF, PE, phosphatidylethanolamine, nitisinone, lysophosphatidylethanolamine, 03 medical and health sciences, dihydroceramide, Human disease modelling, NAFLD, FFA, free fatty acid, LCER, DEG, MUFA, education, phosphatidylcholine, chimeric mouse hepatocytes, FAH, SM, sphingomyelin, ALP, alkaline phosphatase, FA, fatty acid, NTBC, Fatty acid, medicine.disease, differentially expressed gene, lactosylceramide, PNPLA3, patatin-like-phospholipase domain-containing protein 3, Lipid metabolism, chemistry, fatty acid, PUFA, hALB, human albumin, TIRF, transgene-free Il2rg-/-/Rag2-/-/Fah, AST, aspartate aminotransferase, CT, confidence transcript, PC, phosphatidylcholine, monounsaturated fatty acid, DEG, differentially expressed gene, MUFA, monounsaturated fatty acid, Immunology and Allergy, MAG, monoacylglycerol, PUFA, polyunsaturated free FA, CE, cholesteryl ester, CER, diacylglycerol, FAH, fumarylacetoacetate hydrolase, Fatty liver, SM, chimeric human hepatocytes, hepatocellular carcinoma, CBPEGs, cholesterol biosynthesis pathway enzyme genes, CE, MAG, LPC, patatin-like-phospholipase domain-containing protein 3, triacylglycerol, LPE, alkaline phosphatase, sterol regulatory element-binding protein, Polyunsaturated fatty acid, Research Article, CT, NAFLD, non-alcoholic fatty liver disease, FA, HCER, TAG, triacylglycerol, fumarylacetoacetate hydrolase, monoacylglycerol, alanine aminotransferase, Population, cholesterol biosynthesis pathway enzyme genes, Biology, SREBP, PI, phosphatidylinositol, sphingomyelin, lysophosphatidylcholine, WD, ALT, alanine aminotransferase, high confidence transcriptional target, Internal Medicine, medicine, CBPEGs, ceramide, hALB, LCER, lactosylceramide, normal chow, AST, polyunsaturated free FA, WD, Western-type diet, PNPLA3, 030304 developmental biology, Hepatitis, LPC, lysophosphatidylcholine, Hepatology, DAG, non-alcoholic fatty liver disease, NTBC, nitisinone, CMHs, GGT, HCT, high confidence transcriptional target, phosphatidylethanolamine, TAG, Cancer research, CHHs, chimeric human hepatocytes, ALP, Liver function, NC, CER, ceramide, HCC, hepatocellular carcinoma, FFA, DAG, diacylglycerol, Non-alcoholic fatty liver disease

    وصف الملف: application/pdf

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    المؤلفون: Valentin A. Pavlov

    المصدر: Pharmacology & Therapeutics

    مصطلحات موضوعية: 0301 basic medicine, ChAT, choline acetyltransferase, BMI, body mass index, Inflammatory reflex, NLRP3, NLRs nucleotide-binding oligomerization domain (NOD)-like receptors nucleotide-binding oligomerization domain-like receptor family pyrin domain containing-3, Type 2 diabetes, Disease, Bioinformatics, 0302 clinical medicine, AChE, acetylcholinesterase, Medicine, Pharmacology (medical), TLR, toll-like receptors, NF-κB, nuclear factor kappa B, COVID-19, coronavirus disease 2019, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, HDL-C, high density lipoprotein-cholesterol, Vagus Nerve, GI, gastrointestinal, Metabolic syndrome, ICU, intensive care unit, Bioelectronic medicine, VNS, vagus nerve stimulation, 030220 oncology & carcinogenesis, LPS, lipopolysaccharide, MetS, metabolic syndrome, medicine.symptom, SARS-CoV, severe acute respiratory syndrome CoV, NAFLD, non-alcoholic fatty liver disease, NASH, non-alcoholic steatohepatitis, α7nAChR, alpha 7 nicotinic acetylcholine receptor, Inflammation, HRV, heart rate variability, Article, 03 medical and health sciences, NTS, nucleus tractus solitarius, Immune system, DMN, dorsal motor nucleus of the vagus, Humans, Obesity, mAChR, muscarinic acetylcholine receptor, ARDS, acute respiratory distress syndrome, Pharmacology, SARS-CoV-2, ACh, acetylcholine, business.industry, COVID-19, medicine.disease, NA, nucleus ambiguus, IL, interleukin, Vagus nerve, The inflammatory reflex, 030104 developmental biology, MERS-CoV, Middle East respiratory syndrome corona virus, JAK2/STAT3, Janus kinase 2/signal transducer and activator of transcription 3, business, SARS-CoV-2, severe acute respiratory syndrome coronavirus-2