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المساهمون: Basic (bio-) Medical Sciences, Faculty of Medicine and Pharmacy, Supporting clinical sciences, Medical Imaging, Nuclear Medicine, Translational Imaging Research Alliance

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 75, p 75 (2021)
International Journal of Molecular Sciences

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, diagnosis, Lymphocyte, medicine.medical_treatment, Review, Catalysis, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigens, CD, LAG-3, Internal medicine, Neoplasms, Biomarkers, Tumor, Cytotoxic T cell, Medicine, Animals, Humans, cancer, Physical and Theoretical Chemistry, Molecular Biology, Immune Checkpoint Inhibitors, immune checkpoint, lcsh:QH301-705.5, Spectroscopy, business.industry, Organic Chemistry, Cancer, General Medicine, Immunotherapy, medicine.disease, Lymphocyte Activation Gene 3 Protein, Immune checkpoint, Computer Science Applications, Blockade, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), lcsh:QD1-999, Radiology Nuclear Medicine and imaging, 030220 oncology & carcinogenesis, Cancer cell, oncology, immunotherapy, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530b3fbaed3209c36a7ad2074e7c6285Test
https://www.mdpi.com/1422-0067/22/1/75Test

5

Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses

المؤلفون: Xiaohui Pan, Bo Yang, Hongjie Guo, Shuyuan Cheng, Xi Chen, Ling Ding, Qiaojun He, Wenxin Zhang

المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 723-733 (2020)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: TIM-3, T cell immunoglobulin and mucin domain 3, H3K27me3, tri-methylation of lysine 27 on histone H3, MDSCs, myeloid-derived suppressor cells, medicine.medical_treatment, Review, TAA, tumor-associated antigen, DC, dendritic cell, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, LAG-3, lymphocyte activation gene-3, CTLA-4, cytotoxic T lymphocyte antigen 4, Medicine, BETi, bromodomain and extra-terminal motif inhibitors, General Pharmacology, Toxicology and Pharmaceutics, FOXP3, forkhead box P3, HDACi, histone deacetylase inhibitor, Cancer, 0303 health sciences, ACE1, angiotensin converting enzyme, CLL, chronic lymphocytic leukemia, biology, IDO, indoleamine 2,3-dioxygenase, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Tregs, regulatory T cells, PD-L1/PD-1 blockade, CCL22 (MDC), macrophage-derived chemokine, Immunotherapy, TET2, ten-eleven translocation 2, CTLs, cytotoxic T lymphocytes, FDA, U. S. Food and Drug Administration, PD-L1, programmed cell death ligand 1, T cell, CTA, cancer testis antigen, Immune cycle, TIL, tumor infiltrating lymphocytes, Epigenetic regulation, OS, overall survival, 03 medical and health sciences, Immune system, Antigen, PD-L1, TH-1, T helper type 1, DNMT1, DNA methyltransferase 1, MHC, major histocompatibility complex, CX3CL1, C-X3-C motif chemokine ligand 1, IFN-γ, interferon-gamma, 030304 developmental biology, business.industry, lcsh:RM1-950, biochemical phenomena, metabolism, and nutrition, medicine.disease, CXCL, CXC chemokine ligand, Blockade, lcsh:Therapeutics. Pharmacology, APC, antigen-presenting cell, UHRF1, ubiquitin-like PHD and RING finger domain-containing 1, 5-AzaC, 5-azacitidine, ACP1, human red cell acid phosphatase, biology.protein, Cancer research, bacteria, DNMTi, DNA methyltransferase inhibitors, PD-1, programmed cell death 1, business, PRC2, polycomb repressive complex 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ca7b0479f6fea7a89a3e1eb06905c5Test
https://doi.org/10.1016/j.apsb.2019.09.006Test

6

The New Immunotherapy Combinations in the Treatment of Advanced Non-Small Cell Lung Cancer: Reality and Perspectives

المؤلفون: Danilo Rocco, Cesare Gridelli, Luigi Della Gravara

المصدر: Current Clinical Pharmacology

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, Combination therapy, medicine.medical_treatment, MEDLINE, Ipilimumab, immune modulators, NSCLC, combination therapy, 03 medical and health sciences, 0302 clinical medicine, IDO1, Antineoplastic Agents, Immunological, LAG-3, Internal medicine, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Pharmacology (medical), OX40, General Pharmacology, Toxicology and Pharmaceutics, Lung cancer, Chemotherapy, business.industry, TMB, Clinical Pharmacology, General Medicine, Immunotherapy, medicine.disease, 030104 developmental biology, Tolerability, 030220 oncology & carcinogenesis, Nivolumab, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d40e897b3c0d6259d103a8bd5e3cabTest
http://europepmc.org/articles/PMC7497556Test

7

A novel cyclic peptide targeting LAG-3 for cancer immunotherapy by activating antigen-specific CD8+ T cell responses

المؤلفون: Yuanming Qi, Guodong Li, Hongfei Wang, Xinghua Sui, Yanfeng Gao, Guanyu Chen, Wanqiong Li, Wenjie Zhai, Xiuman Zhou

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 6, Pp 1047-1060 (2020)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5371ad86abe5d20d04e1887e733eb2Test
http://europepmc.org/articles/PMC7332792Test

8

Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4

المؤلفون: Ming Yi, Suxia Luo, Shengnan Yu, Linping Xu, Shuang Qin, Kongming Wu

المصدر: Molecular Cancer, Vol 18, Iss 1, Pp 1-14 (2019)
Molecular Cancer

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.drug_class, TIGIT, T-Lymphocytes, T cell, medicine.medical_treatment, TIM-3, Programmed Cell Death 1 Receptor, VISTA, Review, Lymphocyte Activation, Monoclonal antibody, lcsh:RC254-282, Immunomodulation, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Immune system, LAG-3, Neoplasms, Biomarkers, Tumor, medicine, Animals, Humans, CTLA-4 Antigen, Molecular Targeted Therapy, BTLA, Clinical Trials as Topic, biology, Immunotherapy, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immune checkpoint, Treatment Outcome, 030104 developmental biology, medicine.anatomical_structure, B7-H3, Oncology, CTLA-4, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Molecular Medicine, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ab764b0272cb7de85bf00ba3474375Test
http://link.springer.com/article/10.1186/s12943-019-1091-2Test

9

LAG-3 Expression Predicts Outcome in Stage II Colon Cancer

المؤلفون: José A. Galván, Richard Kirsch, Inti Zlobec, Martin D. Berger, Alessandro Lugli, Gaëlle Rhyner Agocs, Heather Dawson, Naziheh Assarzadegan

المصدر: Journal of Personalized Medicine
Volume 11
Issue 8
Rhyner Agocs, Gaëlle; Assarzadegan, Naziheh; Kirsch, Richard; Dawson, Heather; Galván, José A.; Lugli, Alessandro; Zlobec, Inti; Berger, Martin D. (2021). LAG-3 Expression Predicts Outcome in Stage II Colon Cancer. Journal of personalized medicine, 11(8) MDPI 10.3390/jpm11080749 <http://dx.doi.org/10.3390/jpm11080749Test>
Journal of Personalized Medicine, Vol 11, Iss 749, p 749 (2021)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81063814d1da7fa173328f68d037776Test
http://europepmc.org/articles/PMC8398428Test

10

Case Report: Circulating Myeloid-Derived Suppressive-Like Cells and Exhausted Immune Cells in Non-Small Cell Lung Cancer Patients Treated With Three Immune Checkpoint Inhibitors

المؤلفون: Giuseppe Bronte, Alberto Verlicchi, Serena De Matteis, Alice Rossi, Alessandra Affatato, Francesco Giulio Sullo, Caterina Gianni, Matteo Canale, Marco Angelo Burgio, Angelo Delmonte, Michele Milella, Lucio Crinò

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Lung Neoplasms, Myeloid, medicine.medical_treatment, Immunology, immune checkpoint inhibitor, Adenocarcinoma of Lung, Case Report, chemical and pharmacologic phenomena, 03 medical and health sciences, 0302 clinical medicine, Immune system, Cancer immunotherapy, LAG-3, Antineoplastic Combined Chemotherapy Protocols, PD-1, medicine, Humans, Immunology and Allergy, Lung cancer, Immune Checkpoint Inhibitors, Aged, T cell exhaustion, business.industry, Cancer, RC581-607, Middle Aged, biochemical phenomena, metabolism, and nutrition, myeloid-derived suppressor cells, medicine.disease, Ipilimumab, Immune checkpoint, Nivolumab, 030104 developmental biology, medicine.anatomical_structure, CTLA-4, 030220 oncology & carcinogenesis, Cancer research, Myeloid-derived Suppressor Cell, Tumor Escape, Immunologic diseases. Allergy, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ad11e5b5cf86e4ec09d57949b4bf71Test
https://doi.org/10.3389/fimmu.2021.672219Test

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