المؤلفون: Koji Kato, Kiyoshi Ando, Yasuhito Terui, Tadahiko Igarashi, Dai Maruyama, Hidetsugu Kawai, Eiji Kiyohara, Kenya Nakai, Toshiki Uchida, Tomomitsu Miyagaki, Kensei Tobinai, Mamiko Sakata-Yanagimoto, Junya Kuroda, Yoshiki Tokura, Noriko Fukuhara, Jiro Fujita, Takayuki Ishikawa, Kentaro Yonekura, Tadashi Nakanishi, Kazuhito Yamamoto, Risa Matsunaga

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, cutaneous T‐cell lymphoma, Recombinant Fusion Proteins, E7777, Phases of clinical research, Gastroenterology, Drug Administration Schedule, peripheral T‐cell lymphoma, 03 medical and health sciences, 0302 clinical medicine, Japan, Denileukin diftitox, Refractory, Clinical Research, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Diphtheria Toxin, Hypoalbuminemia, CD25, Diphtheria toxin, Binding Sites, business.industry, Cutaneous T-cell lymphoma, Lymphoma, T-Cell, Peripheral, Original Articles, General Medicine, medicine.disease, Survival Analysis, Peripheral T-cell lymphoma, Lymphoma, T-Cell, Cutaneous, Lymphoma, interleukin‐2, Treatment Outcome, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Interleukin-2, Administration, Intravenous, Female, Original Article, Neoplasm Recurrence, Local, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cac3fb385165954f4b66357a15dbc43Test
https://doi.org/10.1111/cas.14906Test

المؤلفون: Larisa Reyderman, Jagadeesh Aluri, Kenya Nakai, Bojan Lalovic, Margaret Moline, Ishani Landry, Takashi Ueno, Satish Dayal, Yukiko Miyajima, Nancy Hall, Gleb Filippov

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: Adult, Male, CYP2B6, Pyridines, Itraconazole, CYP3A, orexin receptor antagonists, Cmax, Pharmaceutical Science, Pharmacology, 030226 pharmacology & pharmacy, Young Adult, 03 medical and health sciences, 0302 clinical medicine, drug‐drug interaction, Pharmacokinetics, Cytochrome P-450 CYP3A, Humans, Medicine, Drug Interactions, Pharmacology (medical), Cytochrome P-450 Enzyme Inducers, Bupropion, business.industry, Brief Report, Middle Aged, Cytochrome P-450 CYP2B6, Pyrimidines, Area Under Curve, 030220 oncology & carcinogenesis, Cytochrome P-450 CYP3A Inhibitors, Midazolam, Female, Brief Reports, business, pharmacokinetics, Fluconazole, lemborexant, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcf08514e8d52bbf289e88aa00268bcTest
https://doi.org/10.1002/cpdd.915Test

المؤلفون: Kenya Nakai, Hirofumi Yasui, Yoshitaka Inaba, Kei Muro, Takuji Okusaka, Masafumi Ikeda, Hiroki Ikezawa, Toshihiko Doi, Takeshi Aramaki, Ryo Nakajima

المصدر: Investigational New Drugs

مصطلحات موضوعية: Monoclonal antibody, Male, 0301 basic medicine, medicine.medical_specialty, Maximum Tolerated Dose, medicine.medical_treatment, Population, Antineoplastic Agents, Antibodies, Monoclonal, Humanized, Gastroenterology, Cohort Studies, 03 medical and health sciences, Phase I, 0302 clinical medicine, Japan, Pharmacokinetics, Antigens, CD, Antigens, Neoplasm, Phase I Studies, Neoplasms, Internal medicine, Humans, Medicine, Tissue Distribution, Pharmacology (medical), Stromal tumor, education, Adverse effect, Aged, Pharmacology, education.field_of_study, Chemotherapy, business.industry, Cancer, Endosialin, Middle Aged, Prognosis, medicine.disease, CD248 antigen inhibitor, 030104 developmental biology, Ontuxizumab, Oncology, Tolerability, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Female, Neoplasm Recurrence, Local, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf6ea021b6eed80e390c3ccaebde41aTest
https://doi.org/10.1007/s10637-018-0713-7Test

المؤلفون: Nancy Hall, Ishani Landry, Jagadeesh Aluri, Bojan Lalovic, Jim Ferry, Kenya Nakai, Margaret Moline

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: Adult, Male, safety, Pyridines, media_common.quotation_subject, insomnia, orexin receptor antagonists, Lemborexant, Pharmaceutical Science, Original Manuscript, Pharmacology, 030226 pharmacology & pharmacy, White People, 03 medical and health sciences, 0302 clinical medicine, Sex Factors, Pharmacokinetics, Asian People, Double-Blind Method, Insomnia, pharmacodynamics, Medicine, Humans, Pharmacology (medical), media_common, Aged, Dose-Response Relationship, Drug, business.industry, Antagonist, Age Factors, Wake time, Articles, Middle Aged, Orexin receptor, Pyrimidines, 030220 oncology & carcinogenesis, Pharmacodynamics, Female, medicine.symptom, business, pharmacokinetics, Vigilance (psychology), Half-Life, lemborexant

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361399b14382b55ca0b5d1c37c3f60a7Test
https://pubmed.ncbi.nlm.nih.gov/32468649Test

المؤلفون: Jagadeesh Aluri, Bhaskar Rege, Margaret Moline, Takashi Yoshinaga, Borje Darpo, Sanae Yasuda, Meijian Zhou, Jim Ferry, Kenya Nakai, Nancy Hall, Patricia Murphy

المصدر: The Journal of Clinical Pharmacology. 57:96-104

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, animal structures, Long QT syndrome, Cmax, Lemborexant, 030204 cardiovascular system & hematology, Pharmacology, Placebo, Models, Biological, 030226 pharmacology & pharmacy, QT interval, Electrocardiography, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Pharmacokinetics, Risk Factors, Internal medicine, Drug Discovery, medicine, Humans, Pharmacology (medical), Dose-Response Relationship, Drug, medicine.diagnostic_test, Concentration Response, business.industry, Middle Aged, medicine.disease, Long QT Syndrome, Cardiology, Female, Orexin Receptor Antagonists, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f375ca17f93af078821ce32248c04d14Test
https://doi.org/10.1002/jcph.785Test

المؤلفون: Kenya Nakai, Kenji Kosaka, Masaki Nakagawa, Manabu Ikeda, Hideaki Miyagishi, Etsuro Mori

المصدر: Journal of the Neurological Sciences. 366:184-190

مصطلحات موضوعية: Male, Dementia with Lewy bodies, Blood Pressure, Neuropsychological Tests, Severity of Illness Index, law.invention, Cognition, 0302 clinical medicine, Piperidines, Randomized controlled trial, law, Cognitive/behavioral, Donepezil, 030212 general & internal medicine, Nootropic Agents, Aged, 80 and over, Dementia/aging, medicine.diagnostic_test, Parkinsonism, Middle Aged, Treatment Outcome, Cytochrome P-450 CYP2D6, Neurology, Indans, Mini-Mental State Examination, Female, Safety, Psychology, Clinical psychology, medicine.drug, Lewy Body Disease, medicine.medical_specialty, Efficacy, Clinical Neurology, Urology, Clinical, 03 medical and health sciences, Rating scale, mental disorders, medicine, Humans, Pharmacokinetis, Pulse, Aged, Mini–Mental State Examination, Dose-Response Relationship, Drug, Body Weight, medicine.disease, Blood pressure, Neurology (clinical), Mental Status Schedule, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dbd06e8fa6d0f6b9a275bc13964c23Test
https://doi.org/10.1016/j.jns.2016.05.001Test

المؤلفون: Hirotsugu Atarashi, Akira Homma, Kenya Nakai, Naoki Kubota, Takao Takase

المصدر: Journal of Alzheimer's disease : JAD. 52(1)

مصطلحات موضوعية: Male, Severity of Illness Index, Double blind, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Japan, Piperidines, Alzheimer Disease, mental disorders, Severity of illness, Outpatients, medicine, Humans, Donepezil, 030212 general & internal medicine, Immediate release, Adverse effect, Nootropic Agents, Cholinesterase, Aged, Psychiatric Status Rating Scales, biology, business.industry, General Neuroscience, General Medicine, Confidence interval, Psychiatry and Mental health, Clinical Psychology, Treatment Outcome, Anesthesia, Delayed-Action Preparations, Indans, biology.protein, Vomiting, Female, Cholinesterase Inhibitors, Geriatrics and Gerontology, medicine.symptom, business, Mental Status Schedule, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a3c92a130b619d6bdf84025de01d27Test
https://pubmed.ncbi.nlm.nih.gov/26967222Test