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المؤلفون: A. Rasim Barutcu, Laura Pölsler, Yvette Wefeld-Neuenfeld, Philipp G. Maass, Atakan Aydin, Katharina Rittscher, Thomas Liehr, Julia Lichtenwald, Sigrid Tinschert, Sylvia Bähring, Anja Weise, Friedrich C. Luft, John L. Rinn
المساهمون: Medical Genetics
المصدر: The EMBO Journal. 37
مصطلحات موضوعية: Interphase/genetics, 0301 basic medicine, Cell type, Cell Nucleus/genetics, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Chromosomes, Human, Pair 17/genetics, medicine, Humans, Chromosomes, Human, Pair 2/genetics, Molecular Biology, In Situ Hybridization, Fluorescence, Chromosome 12, Genetics, Chromosomes, Human, Pair 12/genetics, Histone Deacetylases/genetics, Repressor Proteins/genetics, General Immunology and Microbiology, Mesenchymal Stem Cells/cytology, General Neuroscience, Mesenchymal stem cell, Chromosome, Karyotype, Translocation, Genetic/genetics, HDAC4, 030104 developmental biology, medicine.anatomical_structure, Interphase, Chromosome Deletion, Nucleus, Gene Deletion
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b0d29c3b3acb595fda03dee414610fTest
https://doi.org/10.15252/embj.201696257Test -
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المؤلفون: Raymond J. Pierce, Wolfgang Sippl, Julien Lancelot, Karin Schmidtkunz, Alokta Chakrabarti, Dina Robaa, Jelena Melesina, Tajith B. Shaik, Christophe Romier, Conrad V. Simoben, Manfred Jung, Srinivasaraghavan Kannan, Martin Marek
المساهمون: Romier, Christophe, Martin-Luther-Universität Halle Wittenberg (MLU), Albert-Ludwigs-Universität Freiburg, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), This work and the authors of this article received funding from the European Union’s Seventh Framework Programme for Research, Technological Development and Demonstration under Grant Agreements 241865 (SEtTReND) and 602080 (A-ParaDDisE). Further support was received by the Deutsche Forschungsgemeinschaft (Ju-295/13-1, SI-868/13-1). MM, TBS and CR are supported by institutional funds from the Centre National de la Recherche Scientifique (CNRS), the Institut National de la Santé et de la Recherche Médicale (INSERM) and the Université de Strasbourg., The authors acknowledge the support and the use of resources of the French Infrastructure for Integrated Structural Biology FRISBI ANR-10-INBS-05 and of Instruct-ERIC. We wish to thank members of the ESRF-EMBL joint structural biology groups and the SOLEIL synchrotron for the use of their beamline facilities and for help during data collection. We are grateful to Pierre Legrand (SOLEIL) for his kind assistance for data processing, Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)
المصدر: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Molecules, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Molecules, Vol 23, Iss 3, p 566 (2018)
Molecules; Volume 23; Issue 3; Pages: 566
Molecules, MDPI, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩مصطلحات موضوعية: 0301 basic medicine, Pyrrolidines, MESH: Helminth Proteins/metabolism, MESH: Histone Deacetylases/metabolism, MESH: Histone Deacetylases/genetics, Pharmaceutical Science, MESH: Protein Structure, Secondary, Gene Expression, Apoptosis, Crystallography, X-Ray, Hydroxamic Acids, Molecular Docking Simulation, MESH: Helminth Proteins/antagonists & inhibitors, MESH: Chelating Agents/chemical synthesis, Protein Structure, Secondary, Analytical Chemistry, 0302 clinical medicine, MESH: Structure-Activity Relationship, MESH: Hydroxamic Acids/chemical synthesis, Drug Discovery, MESH: Zinc/metabolism, MESH: Animals, [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], MESH: Histone Deacetylase Inhibitors/pharmacology, Chelating Agents, Anthelmintics, biology, Chemistry, MESH: Anthelmintics/pharmacology, Helminth Proteins, Schistosoma mansoni, epigenetics, crystal structure, docking, histone deacetylase (HDAC) inhibitors, schistosomiasis, virtual screening, MESH: Histone Deacetylases/chemistry, 3. Good health, MESH: Schistosoma mansoni/drug effects, MESH: Pyrrolidines/pharmacology, Zinc, Biochemistry, Chemistry (miscellaneous), Molecular Medicine, Protein Binding, MESH: Apoptosis/drug effects, MESH: Gene Expression, In silico, 030231 tropical medicine, MESH: Zinc/chemistry, Article, Histone Deacetylases, lcsh:QD241-441, 03 medical and health sciences, Structure-Activity Relationship, lcsh:Organic chemistry, MESH: Molecular Docking Simulation, Structure–activity relationship, MESH: Protein Binding, Animals, MESH: Helminth Proteins/genetics, Protein Interaction Domains and Motifs, Physical and Theoretical Chemistry, MESH: Histone Deacetylase Inhibitors/chemical synthesis, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Virtual screening, MESH: Protein Interaction Domains and Motifs, Binding Sites, Organic Chemistry, MESH: Hydroxamic Acids/pharmacology, HDAC8, MESH: Schistosoma mansoni/growth & development, Epigenome, biology.organism_classification, MESH: Crystallography, X-Ray, MESH: Anthelmintics/chemical synthesis, Histone Deacetylase Inhibitors, 030104 developmental biology, MESH: Binding Sites, Docking (molecular), MESH: Chelating Agents/pharmacology, MESH: Schistosoma mansoni/enzymology, MESH: Helminth Proteins/chemistry, MESH: Schistosoma mansoni/genetics, MESH: Pyrrolidines/chemical synthesis
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57756972e5c4439f4e393638be3994bTest
http://europepmc.org/articles/PMC6017931Test -
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المؤلفون: Scott W. Hiebert, Emma De Fabiani, Cinzia Magagnotti, Erika Fiorino, Donatella Caruso, Béatrice Desvergne, Annapaola Andolfo, Maurizio Crestani, Rui Silva, Gaia Cermenati, Nico Mitro, Federica Gilardi, Raffaella Longo, Alessandra Ferrari
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications, vol. 8, no. 1, pp. 93مصطلحات موضوعية: Male, 0301 basic medicine, Adipose Tissue, White, Science, General Physics and Astronomy, Adipose tissue, Adipocytes/physiology, Adipose Tissue, Brown/physiology, Adipose Tissue, White/physiology, Animals, Cell Line, Diet, High-Fat, Gene Expression Regulation/physiology, Gene Silencing, Histone Deacetylases/genetics, Histone Deacetylases/metabolism, Lipid Metabolism, Mice, Mice, Knockout, White adipose tissue, Biology, Histone Deacetylases, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chemistry.chemical_compound, Adipose Tissue, Brown, Adipocytes, PPARA Gene, Fatty acid synthesis, Multidisciplinary, Fatty acid metabolism, Futile cycle, nutritional and metabolic diseases, food and beverages, Lipid metabolism, General Chemistry, HDAC3, 030104 developmental biology, Gene Expression Regulation, chemistry, Biochemistry, lipids (amino acids, peptides, and proteins), hormones, hormone substitutes, and hormone antagonists
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c512383fec48820206bfc3269b78fc0bTest
https://doi.org/10.1038/s41467-017-00182-7Test -
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المؤلفون: Victor Fernandes Vieira, Sandrine Cornaz, Luisa Cironi, Carlo Fusco, Paolo Provero, Giulia Fregni, Ivan Stamenkovic, Igor Letovanec, Michel Aguet, Tanja Petricevic
المصدر: Scientific Reports
Scientific reports, vol. 6, pp. 22113مصطلحات موضوعية: 0301 basic medicine, Beta-catenin, Oncogene Proteins, Fusion, Blotting, Western, Animals, Axin Protein/genetics, Axin Protein/metabolism, Cell Line, Cell Line, Tumor, Gene Expression Profiling/methods, Histone Deacetylases/genetics, Histone Deacetylases/metabolism, Humans, Mice, Microscopy, Confocal, Oncogene Proteins, Fusion/genetics, Oncogene Proteins, Fusion/metabolism, RNA Interference, Repressor Proteins/genetics, Repressor Proteins/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Sarcoma, Synovial/genetics, Sarcoma, Synovial/metabolism, Sarcoma, Synovial/pathology, TCF Transcription Factors/genetics, TCF Transcription Factors/metabolism, Transcription Factors/genetics, Transcription Factors/metabolism, Wnt Signaling Pathway/genetics, beta Catenin/genetics, beta Catenin/metabolism, TCF/LEF family, Histone Deacetylases, Article, Sarcoma, Synovial, 03 medical and health sciences, Axin Protein, AXIN2, Fusion, Wnt Signaling Pathway, Transcription factor, beta Catenin, Gene Expression Profiling, Repressor Proteins, TCF Transcription Factors, Transcription Factors, Multidisciplinary, Oncogene Proteins, Microscopy, Tumor, Synovial, biology, Blotting, Wnt signaling pathway, LRP6, Sarcoma, LRP5, Fusion protein, 030104 developmental biology, Confocal, biology.protein, Cancer research, Western, Co-Repressor Proteins
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60efadcc1928d9d1f484ba21cc89d788Test
https://doi.org/10.1038/srep22113Test -
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المؤلفون: Xuwu Sun, Haiyang Wang, Xiumei Xu, Jinfang Ma, Lixin Zhang, Hailong Guo, Congming Lu, Jean-David Rochaix, Peiqiang Feng, Wei Chi, Dario Leister, Xin Chai
المصدر: Proceedings of the National Academy of Sciences, Vol. 113, No 38 (2016) pp. 10708-10713
مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Carrier Proteins/genetics, Chloroplasts, Chromatin/genetics/radiation effects, Light, Arabidopsis, 01 natural sciences, Gene Expression Regulation, Plant, Flowering Locus C, Arabidopsis/genetics/growth & development, Chloroplasts/genetics/metabolism, Plant/radiation effects, Genetics, Histone Deacetylases/genetics, Multidisciplinary, biology, food and beverages, Biological Sciences, Chromatin, Chloroplast, Arabidopsis Proteins/genetics, ddc:580, Signal Transduction, Flowers/genetics/growth & development/radiation effects, PHD Zinc Fingers/genetics, MADS Domain Proteins, Flowers, Histone Deacetylases, Chromatin remodeling, 03 medical and health sciences, MADS Domain Proteins/genetics, ddc:570, Transcription factor, Cell Nucleus, Arabidopsis Proteins, fungi, biology.organism_classification, 030104 developmental biology, Gene Expression Regulation, Histone deacetylase complex, Retrograde signaling, Signal Transduction/genetics, Cell Nucleus/genetics/radiation effects, Carrier Proteins, PHD Zinc Fingers, Transcription Factors, 010606 plant biology & botany
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79f38ecf505dde84e75748016fe17c0Test
https://archive-ouverte.unige.ch/unige:111261Test -
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المؤلفون: Marino Zerial, Sandrine Uttenweiler-Joseph, Savvas Christoforidis, Angelika Giner, Marta Miaczynska, Bianca Habermann, Robert G. Parton, Anna Shevchenko, Matthias Wilm
المساهمون: Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Max-Planck-Gesellschaft, European Molecular Biology Laboratory [Heidelberg] (EMBL), Institute for Molecular Bioscience, University of Queensland [Brisbane]
المصدر: Cell
Cell, Elsevier, 2004, 116 (3), pp.445-456. ⟨10.1016/s0092-8674(04)00117-5⟩
ResearcherIDمصطلحات موضوعية: Plasma protein binding, Binding Sites/genetics, Cell membrane, Transduction (genetics), 0302 clinical medicine, Endocytosis/*physiology, Carrier Proteins/genetics/*metabolism, Histone Deacetylases/genetics, 0303 health sciences, rab5 GTP-Binding Proteins/genetics/*metabolism, Cell Division/genetics, Endocytosis, Cell biology, Protein Transport, Cell Compartmentation/genetics, medicine.anatomical_structure, Guanosine Triphosphate, Signal transduction, Proto-Oncogene Proteins, Cell Division, Protein Binding, Signal Transduction, Mi-2 Nucleosome Remodeling and Deacetylase Complex, Cell Nucleus/*metabolism/ultrastructure, Proto-Oncogene Proteins c-akt, Endosome, Endosomes, Protein Serine-Threonine Kinases, Biology, Histone Deacetylases, General Biochemistry, Genetics and Molecular Biology, Protein Binding/genetics, Endosomes/*metabolism/ultrastructure, 03 medical and health sciences, Cell Membrane/*metabolism/ultrastructure, medicine, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Protein-Serine-Threonine Kinases, rab5 GTP-Binding Proteins, 030304 developmental biology, Cell Nucleus, Binding Sites, Biochemistry, Genetics and Molecular Biology(all), Cell Membrane, Protein Transport/genetics, Cell Compartmentation, Microscopy, Electron, Guanosine Triphosphate/metabolism, Histone deacetylase complex, Signal Transduction/genetics, Carrier Proteins, 030217 neurology & neurosurgery, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7d1003cd7cbcb1b3567790efdfb313Test
https://doi.org/10.1016/s0092-8674Test(04)00117-5