المؤلفون: Ali M. Tabish, Elke Ericson, Björn Tyrberg, David M. Smith, Chandrasekhar Kanduri, Hanne Scholz, Shadab Abadpour, Tanmoy Mondal, Ralph Knöll, Magnus Althage, Alex Xianghua Zhou

المصدر: American Journal of Physiology-Endocrinology and Metabolism. 320:E846-E857

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Physiology, Cell growth, Endocrinology, Diabetes and Metabolism, Wnt signaling pathway, RNA, Type 2 diabetes, Biology, medicine.disease, Long non-coding RNA, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Endocrinology, 030220 oncology & carcinogenesis, Physiology (medical), Internal medicine, Diabetes mellitus, medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::050406a2c02101242d45851c14853faaTest
https://doi.org/10.1152/ajpendo.00335.2020Test

المؤلفون: Elke Ericson, Madelene Lindqvist, Ulf Gehrmann, Rajneesh Malhotra, Lena Ripa, Mei Ding, Johan Brengdahl, Stefan von Berg

المصدر: ACS Chemical Biology. 14:543-553

مصطلحات موضوعية: 0301 basic medicine, Phenotypic screening, Drug Evaluation, Preclinical, chemical and pharmacologic phenomena, Biology, T-Lymphocytes, Regulatory, 01 natural sciences, Biochemistry, Treg cell, Small Molecule Libraries, Glycogen Synthase Kinase 3, Structure-Activity Relationship, 03 medical and health sciences, Protein Domains, Forkhead Box, Humans, CTLA-4 Antigen, RNA, Small Interfering, Transcription factor, 010405 organic chemistry, Effector, FOXP3, Forkhead Transcription Factors, hemic and immune systems, Histone-Lysine N-Methyltransferase, General Medicine, 0104 chemical sciences, Cell biology, Phenotype, 030104 developmental biology, Gene Expression Regulation, Gene Knockdown Techniques, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044cf7a8366c5fde221b2d170b641f55Test
https://doi.org/10.1021/acschembio.9b00075Test

المؤلفون: Magnus Althage, Luna Simona Pane, Frank Seeliger, Mikael Bjursell, Ralph Knöll, Daniel Lindén, Katja Madeyski-Bengtson, Marta Perez-Alcazar, Roberto Nitsch, Mohammad Bohlooly-Y, Ryan Hicks, Alba Carreras, Marcello Maresca, Rosie Perkins, Jan Borén, Amir Taheri-Ghahfarokhi, Lorenz M. Mayr, Elke Ericson, Michelle J. Porritt, Pinar Akcakaya

المصدر: BMC Biology, Vol 17, Iss 1, Pp 1-14 (2019)
BMC Biology

مصطلحات موضوعية: Physiology, Hypercholesterolemia, Mice, Transgenic, Plant Science, Biology, Genome, General Biochemistry, Genetics and Molecular Biology, PCSK9, Base editing, 03 medical and health sciences, Mice, 0302 clinical medicine, Genome editing, Structural Biology, Gene knockin, Animals, Humans, Guide RNA, lcsh:QH301-705.5, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Gene Editing, 0303 health sciences, Cell Biology, Proprotein convertase, Cell biology, Evolocumab, Disease Models, Animal, Cholesterol, Liver, lcsh:Biology (General), Humanized mouse, Proprotein Convertase 9, CRISPR-Cas9, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery, Developmental Biology, Biotechnology, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66078274e7f09cb641aa7f88b07be760Test
http://link.springer.com/article/10.1186/s12915-018-0624-2Test

المؤلفون: Leif Aasehaug, Lisa U. Magnusson, Amir Taheri-Ghahfarokhi, Roberto Nitsch, Frank Seeliger, Mohammad Bohlooly-Y, Marcello Maresca, Lorenz M. Mayr, Elke Ericson, Therese Admyre, Maryam Clausen, Michelle J. Porritt, John Wiseman, Mikael Bjursell

المصدر: EBioMedicine, Vol 29, Iss, Pp 104-111 (2018)
EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, Transgene, Liver fibrosis, Genetic Vectors, Gene Expression, lcsh:Medicine, Mice, Transgenic, α1-antitrypsin deficiency, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Adenoviridae, Mice, 03 medical and health sciences, Transduction, Genetic, Fibrosis, alpha 1-Antitrypsin Deficiency, Gene expression, medicine, Animals, Humans, Transgenes, Gene, Cell Proliferation, Gene Editing, Mutation, lcsh:R5-920, Alpha 1-antitrypsin deficiency, lcsh:R, General Medicine, medicine.disease, Phenotype, Disease Models, Animal, medicine.anatomical_structure, 030104 developmental biology, alpha 1-Antitrypsin, Hepatocyte, Neutrophil elastase, Humanized mouse, biology.protein, Cancer research, CRISPR/Cas9 gene editing, Protein aggregation, CRISPR-Cas Systems, lcsh:Medicine (General), Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf00afa857797ceb9b4f7d0d1278be6Test
http://www.sciencedirect.com/science/article/pii/S2352396418300690Test

المؤلفون: Amalia I. Paunovic, Elke Ericson, Karin Gedda, Anna Jonebring, Anneli Nordqvist, Ola Engkvist, Gunnar Grönberg, Elizabeth Mouchet, Alexander J. Kvist, Martin R. Brown, Qing-Dong Wang, Alleyn T. Plowright, Marie-José Goumans, Lauren Drowley

المصدر: ACS Chemical Biology, 12(1), 132-141

مصطلحات موضوعية: 0301 basic medicine, Cardiac progenitors, Phenotypic screening, Cell, Cell Culture Techniques, Biology, Biochemistry, Cardiac regeneration, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Humans, Regeneration, Cells, Cultured, Progenitor, Cell Proliferation, Phenotypic assay, Myocardium, Translation (biology), Heart, General Medicine, Fibroblasts, Phenotype, Cell biology, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Molecular Medicine, Pericardium

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc360e7413d3064aa113ee98a794f61Test
https://pubmed.ncbi.nlm.nih.gov/28103692Test

المؤلفون: Fanny Langlet, Christoph Buettner, Daniel Lindén, Kumiko S. Aizawa, Domenico Accili, Ling Wang, Rebecca A. Haeusler, Elke Ericson, Anders Johansson, Joshua R. Cook, Tyrrell Norris

المصدر: Cell. 171:824-835.e18

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Repressor, FOXO1, Biology, Histone Deacetylases, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, Insulin resistance, Internal medicine, Glucokinase, medicine, Animals, Humans, Phosphorylation, Promoter Regions, Genetic, Cells, Cultured, Mice, Knockout, Forkhead Box Protein O1, Lipogenesis, Insulin, Acetylation, medicine.disease, Repressor Proteins, Sin3 Histone Deacetylase and Corepressor Complex, Glucose, HEK293 Cells, 030104 developmental biology, Endocrinology, Glucose-6-Phosphatase, Hepatocytes, biology.protein, Insulin Resistance, Corepressor, hormones, hormone substitutes, and hormone antagonists, Glucose 6-phosphatase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f2263a131ef5f9509ac74e67799a96Test
https://doi.org/10.1016/j.cell.2017.09.045Test

المؤلفون: Dahlia Kasimer, Glenn S. Cowley, Troy Ketela, Anthony Arnoldo, David E. Root, Corey Nislow, Judice Ly Y. Koh, Elke Ericson, Ron Ammar, Dina Karamboulas, Tanja Durbic, Kahlin Cheung-Ong, Lawrence E. Heisler, Kevin R. Brown, Shuba Gopal, Andrew M. Smith, Jason Moffat, Jennifer K. Grenier, Guri Giaever, Kim Blakely, Xiaoping Yang, Anuradha Surendra

المصدر: BMC Genomics, Vol 12, Iss 1, p 213 (2011)
BMC Genomics

مصطلحات موضوعية: Quality Control, Therapeutic gene modulation, lcsh:QH426-470, lcsh:Biotechnology, Genomics, Saccharomyces cerevisiae, Computational biology, Biology, Proteomics, Small hairpin RNA, Mice, Open Reading Frames, 03 medical and health sciences, 0302 clinical medicine, RNA interference, lcsh:TP248.13-248.65, Genetics, Animals, Humans, Genetic Testing, Oligonucleotide Array Sequence Analysis, 030304 developmental biology, 0303 health sciences, Methodology Article, genomic DNA, lcsh:Genetics, RNA Interference, DNA microarray, Software, 030217 neurology & neurosurgery, Biotechnology, Genetic screen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d84b0bbba9895ecaba32cb7c2d971aTest
http://www.biomedcentral.com/1471-2164/12/213Test

المؤلفون: Corey Nislow, Marinella Gebbia, Elke Ericson, Lawrence E. Heisler, Mike Tyers, Guri Giaever, Jan Wildenhain

المصدر: Ericson, E, Gebbia, M, Heisler, L E, Wildenhain, J, Tyers, M, Giaever, G & Nislow, C 2008, ' Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast ', PLoS Genetics, vol. 4, no. 8, e1000151, pp.-. https://doi.org/10.1371/journal.pgen.1000151Test
PLoS Genetics
PLoS Genetics, Vol 4, Iss 8, p e1000151 (2008)

مصطلحات موضوعية: Cancer Research, ved/biology.organism_classification_rank.species, Drug Evaluation, Preclinical, Drug Resistance, Pharmacology, 0302 clinical medicine, Genetics(clinical), Genetics (clinical), Clozapine, Oligonucleotide Array Sequence Analysis, media_common, 0303 health sciences, Genetics and Genomics/Functional Genomics, Cell Polarity, Telomere, 3. Good health, Chromatin, Genetics and Genomics/Gene Function, Protein Transport, Genome, Fungal, Research Article, medicine.drug, Drug, Saccharomyces cerevisiae Proteins, lcsh:QH426-470, media_common.quotation_subject, Saccharomyces cerevisiae, Biology, 03 medical and health sciences, medicine, Genetics, Humans, Genetics and Genomics/Genomics, Model organism, Gene, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Psychotropic Drugs, ved/biology, Gene Expression Profiling, Genetics and Genomics, Lipid Metabolism, biology.organism_classification, Yeast, Gene expression profiling, lcsh:Genetics, Protein Biosynthesis, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a653750956767887e47698b99d69260fTest
https://www.pure.ed.ac.uk/ws/files/8116364/PLOS_2008_Tyers_M.pdfTest

المؤلفون: Mohammed Bellaoui, Guri Giaever, Lisa Yu, Elke Ericson, Andres Lopez, Abdellah Hamal, Lawrence E. Heisler, Brahim El Bali, Corey Nislow, Charles Boone, Grant W. Brown, Angus McQuibban, Abderrahmane Anaflous

المصدر: PLoS Genetics, Vol 4, Iss 11, p e1000284 (2008)
PLoS Genetics

مصطلحات موضوعية: Cancer Research, Antifungal Agents, DNA Repair, lcsh:QH426-470, Pyridines, DNA damage, DNA repair, Saccharomyces cerevisiae, Genetics and Genomics/Pharmacogenomics, 01 natural sciences, 03 medical and health sciences, Chemical Biology, Genetics, medicine, Humans, Molecular Biology, Cells, Cultured, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, 0303 health sciences, biology, 010405 organic chemistry, Genetics and Genomics/Functional Genomics, Mutagenesis, biology.organism_classification, Yeast, Mitochondria, 0104 chemical sciences, Nuclear DNA, lcsh:Genetics, Pyrimidines, Mechanism of action, Biochemistry, medicine.symptom, DNA Damage, Signal Transduction, Research Article, Nucleotide excision repair

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f6e3c747665c48072cc124af4222c0Test
https://doi.org/10.1371/journal.pgen.1000284Test