نتائج البحث - "Alberto M. Martelli"

1

Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer

المؤلفون: Alberto M. Martelli, Francesca Paganelli, Sandra Marmiroli, Francesca Chiarini, Camilla Evangelisti

المساهمون: C. Evangelisti, F. Chiarini, F. Paganelli, S. Marmiroli, Alberto M. Martelli.

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Protein Kinase Inhibitor, Antineoplastic Agents, Target therapies Drug-resistance Cell signaling pathways Metabolism Mutations, Targeted therapy, Antineoplastic Agent, 03 medical and health sciences, Cell signaling pathway, Glycogen Synthase Kinase 3, 0302 clinical medicine, Neoplasms, Animals, Humans, Medicine, Protein Kinase Inhibitors, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Drug-resistance, TOR Serine-Threonine Kinase, Cell growth, Kinase, business.industry, Animal, TOR Serine-Threonine Kinases, Cancer, Cell Biology, Target therapie, medicine.disease, 030104 developmental biology, Metabolism, 030220 oncology & carcinogenesis, Cancer cell, Mutation, Cancer research, Neoplasm, Signal transduction, business, Human, Signal Transduction

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7ed78981a6168532b38d4a17e47087Test
http://hdl.handle.net/11585/770839Test

2

Sensitivity of pancreatic cancer cells to chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals can be regulated by WT-TP53

المؤلفون: Lucio Cocco, Linda S. Steelman, Giuseppe Montalto, Shaw M. Akula, Stephen L. Abrams, James A. McCubrey, Saverio Candido, Alberto M. Martelli, Agnieszka Gizak, Stefano Ratti, Dariusz Rakus, Massimo Libra, Melchiorre Cervello

المساهمون: S.L. Abrams, S.M. Akula, A.M. Martelli, L. Cocco, S. Ratti, M. Libra, S. Candido, G.Montalto, M. Cervello, A. Gizak, D. Rakus, L.S. Steelman, J.A. McCubrey.

المصدر: Advances in Biological Regulation
79 (2021). doi:10.1016/j.jbior.2020.100780
info:cnr-pdr/source/autori:Abrams SL; Akula SM; Martelli AM; Cocco L; Ratti S; Libra M; Candido S; Montalto G; Cervello M; Gizak A; Rakus D; Steelman LS; McCubrey JA;/titolo:Sensitivity of pancreatic cancer cells to chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals can be regulated by WT-TP53/doi:10.1016%2Fj.jbior.2020.100780/rivista:Advances in Biological Regulation (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:79

مصطلحات موضوعية: Male, 0301 basic medicine, Drug, Cancer Research, miRs, endocrine system diseases, media_common.quotation_subject, Signal transduction inhibitors, Targeted therapeutic, Antineoplastic Agents, Malignancy, medicine.disease_cause, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, 0302 clinical medicine, Chloroquine, Pancreatic cancer, Genetics, medicine, Humans, TP53, Molecular Biology, neoplasms, Signal transduction inhibitor, Targeted therapeutics, Cell Proliferation, media_common, target therapeutics, Cell growth, business.industry, Cancer, medicine.disease, digestive system diseases, Metformin, Pancreatic Neoplasms, 030104 developmental biology, 030220 oncology & carcinogenesis, Dietary Supplements, Mutation, Cancer research, Molecular Medicine, Female, KRAS, Tumor Suppressor Protein p53, business, Signal Transduction, medicine.drug, Drug sensitivity

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4dc94b168075da14e21c4cde71eb4bTest
http://hdl.handle.net/11585/855470Test

3

Cancer therapy and treatments during COVID-19 era

المؤلفون: Monica Notarbartolo, Jörg Bäsecke, Massimo Libra, Giuseppe Montalto, Melchiorre Cervello, Linda S. Steelman, James A. McCubrey, Alberto M. Martelli, Giulia Ramazzotti, Lucio Cocco, Saverio Candido, Shaw M. Akula, Kvin Lerpiriyapong, Stephen L. Abrams, William L. Blalock, Stefano Ratti, Manuela Piazzi, Matilde Y. Follo

المساهمون: Akula S.M., Abrams S.L., Steelman L.S., Candido S., Libra M., Lerpiriyapong K., Cocco L., Ramazzotti G., Ratti S., Follo M.Y., Martelli A.M., Blalock W.L., Piazzi M., Montalto G., Cervello M., Notarbartolo M., Basecke J., McCubrey J.A.

المصدر: Advances in Biological Regulation
77 (2020). doi:10.1016/j.jbior.2020.100739
info:cnr-pdr/source/autori:Shaw MAkula; Stephen L Abrams; Linda SSteelman; SaverioCandido; MassimoLibra; KvinLerpiriyapong; LucioCocco; GiuliaRamazzotti; Stefano Ratti; Matilde YFollo; Alberto MMartelli; William L Blalock; Manuela Piazzi; Giuseppe Montalto; Melchiorre Cervello; Monica Notarbartolo; Jorg Basecke; James A McCubrey;/titolo:Cancer therapy and treatments during COVID-19 era/doi:10.1016%2Fj.jbior.2020.100739/rivista:Advances in Biological Regulation (Print)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:77

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Disease, Comorbidity, Antineoplastic Agent, 0302 clinical medicine, Repurposing approved drug, Neoplasms, Pandemic, Medicine, Viral, Cancer, Natural products, Vitamins, Spike Glycoprotein, Host-Pathogen Interaction, Drug repositioning, 030220 oncology & carcinogenesis, Host-Pathogen Interactions, Spike Glycoprotein, Coronavirus, Molecular Medicine, Nutraceutical, Angiotensin-Converting Enzyme 2, Nutraceuticals, Coronavirus Infections, Human, Hydroxychloroquine, Signal Transduction, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pneumonia, Viral, Antineoplastic Agents, Peptidyl-Dipeptidase A, Antiviral Agents, Natural product, Vitamin, Article, 03 medical and health sciences, Betacoronavirus, Genetics, Humans, Intensive care medicine, Molecular Biology, Pandemics, Trace Element, Antiviral Agent, Betacoronaviru, Coronavirus Infection, business.industry, SARS-CoV-2, Cance, Repurposing approved drugs, Drug Repositioning, rNatural products, COVID-19, Pneumonia, medicine.disease, Review article, Trace Elements, Coronavirus, 030104 developmental biology, Gene Expression Regulation, Settore BIO/14 - Farmacologia, Neoplasm, business, Spike Glycoprotein, Coronaviru

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c69c323af20dd5a069b199c4e1e36d7Test
http://www.cnr.it/prodotto/i/432820Test

4

Drug discovery targeting the mTOR pathway

المؤلفون: Alberto M. Martelli, James A. McCubrey, Francesca Buontempo

المساهمون: A.M. Martelli, F. Buontempo, J.A. McCubrey

المصدر: Clinical Science. 132:543-568

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91789fa7b7e6b1a5a1c30733caf238daTest
https://doi.org/10.1042/cs20171158Test

5

Advances in understanding the mechanisms of evasive and innate resistance to mTOR inhibition in cancer cells

المؤلفون: Alberto M. Martelli, James A. McCubrey, Giovanna Lattanzi, Camilla Evangelisti, Francesca Chiarini

المساهمون: F. Charini, C. Evangelisti, G. Lattanzi, J.A. McCubrey, A.M. Martelli.

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Mechanistic Target of Rapamycin Complex 2, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Cell signaling pathways, Drug-resistance, Epigenetics, Metabolism, Mutations, Target therapies, mTORC2, Epigenesis, Genetic, Targeted therapy, Cell signaling pathway, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Humans, Protein Kinase Inhibitors, Molecular Biology, PI3K/AKT/mTOR pathway, TOR Serine-Threonine Kinases, Epigenetic, Cancer, Cell Biology, medicine.disease, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Cancer cell, Cancer research, Signal transduction, Signal Transduction

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f59caed77b4cc3dc97570037c792e6Test
https://hdl.handle.net/11380/1288364Test

6

Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals

المساهمون: Candido, Saverio, Abrams, Stephen L, Steelman, Linda S, Lertpiriyapong, Kvin, Martelli, Alberto M, Cocco, Lucio, Ratti, Stefano, Follo, Matilde Y, Murata, Ramiro M, Rosalen, Pedro L, Bueno-Silva, Bruno, de Alencar, Severino Matia, Lombardi, Paolo, Mao, Weifeng, Montalto, Giuseppe, Cervello, Melchiorre, Rakus, Dariusz, Gizak, Agnieska, Lin, Heng-Liang, Libra, Massimo, Akula, Shaw M, McCubrey, James A, S. Candido, S.L. Abrams, L.S. Steelman, K. Lertpiriyapong, A.M. Martelli, L. Cocco, S. Ratti, M.Y. Follo, R.M. Murata, P.L. Rosalen, B. Bueno-Silva, S. Matias de Alencar, P. Lombardi, W. Mao, G. Montalto, M. Cervello, D. Rakus, A. Gizak, H.-L. Lin, M. Libra, S. Akula, J.A. McCubrey.

المصدر: Advances in Biological Regulation
(2019): 22–40. doi:10.1016/j.jbior.2019.03.002
info:cnr-pdr/source/autori:Candido S; Abrams SL; Steelman LS; Lertpiriyapong K; Martelli AM; Cocco L; Ratti S; Follo MY; Murata RM; Rosalen PL; Bueno-Silva B; de Alencar SM; Lombardi P; Mao W; Montalto G; Cervello M; Rakus D; Gizak A; Lin H-L; Libra M; Akula SM; McCubrey JA;/titolo:Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals/doi:10.1016%2Fj.jbior.2019.03.002/rivista:Advances in Biological Regulation (Print)/anno:2019/pagina_da:22/pagina_a:40/intervallo_pagine:22–40/volume
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Nutlin-3a, Settore MED/09 - Medicina Interna, endocrine system diseases, medicine.medical_treatment, medicine.disease_cause, Piperazines, Targeted therapy, 0302 clinical medicine, TP53, Mutation, biology, Chemistry, Imidazoles, Proto-Oncogene Proteins c-mdm2, Oxaliplatin, Targeted Therapeutics, Drug sensitivity, Nutraceuticals, Targeted therapeutics, 030220 oncology & carcinogenesis, Molecular Medicine, Mdm2, Nutraceutical, Signal transduction, Carcinoma, Pancreatic Ductal, Signal Transduction, medicine.drug, Antineoplastic Agents, Irinotecan, 03 medical and health sciences, Cell Line, Tumor, Pancreatic cancer, Genetics, medicine, Humans, Molecular Biology, neoplasms, Chemotherapy, medicine.disease, digestive system diseases, Pancreatic Neoplasms, 030104 developmental biology, Cell culture, Dietary Supplements, biology.protein, Cancer research, TERAPÊUTICA MÉDICA, Tumor Suppressor Protein p53

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b27b8241a23b78e27f036ba04f82278Test
http://www.scopus.com/record/display.url?eid=2-s2.0-85062951318&origin=inwardTest

7

Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals

المؤلفون: Linda S. Steelman, Pedro Luiz Rosalen, Paolo Lombardi, Marco Falasca, Giuseppe Montalto, Ramiro Mendonça Murata, Lucio Cocco, Massimo Libra, Li V. Yang, Stefano Ratti, James A. McCubrey, Kvin Lertpiriyapong, Melchiorre Cervello, Saverio Candido, Alberto M. Martelli, Stephen L. Abrams

المساهمون: Abrams S.L., Lertpiriyapong K., Yang L.V., Martelli A.M., Cocco L., Ratti S., Falasca M., Murata R.M., Rosalen P.L., Lombardi P., Libra M., Candido S., Montalto G., Cervello M., Steelman L.S., McCubrey J.A.

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Paclitaxel, endocrine system diseases, medicine.medical_treatment, Targeted therapeutic, Irinotecan, Deoxycytidine, Targeted therapy, Glycogen Synthase Kinase 3, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Pancreatic cancer, Genetics, medicine, Humans, Doxorubicin, TP53, Signal transduction inhibitor, neoplasms, Molecular Biology, Cell Proliferation, Cisplatin, Chemotherapy, business.industry, Pancreatic Neoplasm, medicine.disease, Gemcitabine, digestive system diseases, Pancreatic Neoplasms, Oxaliplatin, 030104 developmental biology, chemistry, Fluorouracil, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, business, Drug sensitivity, Human, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09368c38430d430795edaa35c88ed717Test
http://hdl.handle.net/20.500.11769/334720Test

8

Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells-Power of nutraceuticals

المؤلفون: James A. McCubrey, Lucio Cocco, Giuseppe Montalto, Melchiorre Cervello, Kvin Lertpiriyapong, Massimo Libra, Saverio Candido, Ramiro Mendonça Murata, Pedro Luiz Rosalen, Stephen L. Abrams, Paolo Lombardi, Stefano Ratti, Alberto M. Martelli, Linda S. Steelman, Agnieszka Gizak, Dariusz Rakus

المساهمون: McCubrey, James A., Abrams, Stephen L., Lertpiriyapong, Kvin, Cocco, Lucio, Ratti, Stefano, Martelli, Alberto M., Candido, Saverio, Libra, Massimo, Murata, Ramiro M., Rosalen, Pedro L., Lombardi, Paolo, Montalto, Giuseppe, Cervello, Melchiorre, Gizak, Agnieszka, Rakus, Dariusz, Steelman, Linda S.

المصدر: Advances in biological regulation. 67

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f432ff1b66ee9c95e404dad0dfa0933bTest
https://pubmed.ncbi.nlm.nih.gov/28988970Test

9

Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases

المؤلفون: Dariusz Rakus, Melchiorre Cervello, Giuseppe Montalto, Steve L. Abrams, Saverio Candido, Agnieszka Gizak, James A. McCubrey, Lucio Cocco, Stefano Ratti, Linda S. Steelman, Alberto M. Martelli, Massimo Libra, Kvin Lertpiriyapong

المساهمون: Mccubrey, J., Lertpiriyapong, K., Steelman, L., Abrams, S., Cocco, L., Ratti, S., Martelli, A., Candido, S., Libra, M., Montalto, G., Cervello, M., Gizak, A., Rakus, D., Mccubrey, James A., Lertpiriyapong, Kvin, Steelman, Linda S., Abrams, Steve L., Cocco, Lucio, Ratti, Stefano, Martelli, Alberto M., Candido, Saverio, Libra, Massimo, Montalto, Giuseppe, Cervello, Melchiorre, Gizak, Agnieszka, Rakus, Dariusz

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Curcumin, Berberine, mTORC1, Pharmacology, Resveratrol, Mechanistic Target of Rapamycin Complex 1, Protective Agents, Natural product, 03 medical and health sciences, chemistry.chemical_compound, Glycogen Synthase Kinase 3, Phosphatidylinositol 3-Kinases, Genetic, Neoplasms, Osteoarthritis, Stilbenes, Genetics, PTEN, Humans, Curcuma, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Inflammation, Natural products, biology, PTEN Phosphohydrolase, Neurodegenerative Diseases, biology.organism_classification, 030104 developmental biology, Biochemistry, chemistry, Gene Expression Regulation, Cardiovascular Diseases, biology.protein, Molecular Medicine, Proto-Oncogene Proteins c-akt, Signal Transduction

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cca73cae2ea1313b2b3369fc8ae56c8Test
http://hdl.handle.net/20.500.11769/318301Test

10

Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis

المؤلفون: Melchiorre Cervello, Massimo Libra, Alberto M. Martelli, James A. McCubrey, Montalto G, Kvin Lertpiriyapong, Li V. Yang, Stephen L. Abrams, Timothy L. Fitzgerald, Dariusz Rakus, Agnieszka Gizak, Linda S. Steelman, Lucio Cocco

المساهمون: Mccubrey, J., Lertpiriyapong, K., Fitzgerald, T., Martelli, A., Cocco, L., Rakus, D., Gizak, A., Libra, M., Cervello, M., Montalto, G., Yang, L., Abrams, S., Steelman, L., Mccubrey, Ja, Lertpiriyapong, K, Fitzgerald, Tl, Martelli, Am, Cocco, L, Rakus, D, Gizak, A, Libra, M, Cervello, M, Montalto, G, Yang, Lv, Abrams, Sl, Steelman, Ls.

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, Metastasi, medicine.disease_cause, Metastasis, Antineoplastic Agent, Invasion, Neoplasms, TP53, Neoplasm Metastasis, bcl-2-Associated X Protein, Aza Compound, Proto-Oncogene Protein, Apoptosis Regulatory Protein, biology, Cell Cycle, miR, MicroRNA, Cell cycle, Cell biology, Neoplasm Metastasi, Gene Expression Regulation, Neoplastic, Nutlin-3 chemosensitivity, Mdm2, Molecular Medicine, Human, Signal Transduction, Cyclin-Dependent Kinase Inhibitor p21, Tumor suppressor gene, miRs, Antineoplastic Agents, Cellular senescence, MDM2, 03 medical and health sciences, Bcl-2-associated X protein, Genetic, Proto-Oncogene Proteins, microRNA, Genetics, medicine, Humans, Neoplasm Invasiveness, neoplasms, Molecular Biology, Cell Proliferation, Neoplasm Invasivene, Aza Compounds, Oncomir, Bridged Bicyclo Compounds, Heterocyclic, MicroRNAs, 030104 developmental biology, Tumor progression, biology.protein, Neoplasm, Tumor Suppressor Protein p53, Carcinogenesis, Apoptosis Regulatory Proteins

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1192ae9f1efa26d3fc891ed0a71625aTest
http://hdl.handle.net/20.500.11769/32998Test

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