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المؤلفون: Elise Merritt, Chang S. Chan, Nicola Barnard, Bing Xia, Ying Chen, Anchal Sharma, Amar H. Mahdi, Jorge S. Reis-Filho, Subhajyoti De, Shridar Ganesan, Pier Selenica, Britta Weigelt, Yanying Huo
المصدر: Genes & Diseases. 9:807-813
مصطلحات موضوعية: 0301 basic medicine, Mutation, endocrine system diseases, animal diseases, PALB2, Mutant, Cell Biology, Biology, medicine.disease_cause, medicine.disease, Biochemistry, Germline, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Conditional gene knockout, medicine, Cancer research, Osteosarcoma, skin and connective tissue diseases, Carcinogenesis, Molecular Biology, Genetics (clinical), Exome sequencing
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b323d0dc1662d6f972fa0b181e82ccfTest
https://doi.org/10.1016/j.gendis.2020.08.012Test -
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المؤلفون: Xiang Zhou, Qian Hao, Shanshan Wang, Yajie Chen, Xiaohua Wu, Jiajia Li, Hua Lu
المصدر: Genes & Diseases. 9:705-716
مصطلحات موضوعية: 0301 basic medicine, Mutant, Cancer, Cell Biology, Biology, medicine.disease, Biochemistry, Ubiquitin ligase, RING finger domain, 03 medical and health sciences, Ovarian tumor, 030104 developmental biology, 0302 clinical medicine, Ubiquitin, 030220 oncology & carcinogenesis, Ovarian carcinoma, medicine, biology.protein, Cancer research, Ovarian cancer, Molecular Biology, Genetics (clinical)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d2dcb86c6fa5f469cb04a68d12a79eTest
https://doi.org/10.1016/j.gendis.2020.11.007Test -
3
المؤلفون: Hannah Neiswender, Graydon B. Gonsalvez, Chandler H. Goldman, Rajalakshmi Veeranan-Karmegam
المصدر: Dev Biol
مصطلحات موضوعية: Leucine zipper, animal structures, Protein Conformation, Dynein, Mutant, Biology, Immunoglobulin light chain, Article, 03 medical and health sciences, Oogenesis, 0302 clinical medicine, Cell polarity, medicine, Molecular motor, Animals, Drosophila Proteins, RNA, Messenger, Molecular Biology, 030304 developmental biology, Leucine Zippers, 0303 health sciences, Messenger RNA, Chemistry, Ovary, fungi, Dyneins, RNA, Cell Biology, Oocyte, Phenotype, Cell biology, medicine.anatomical_structure, embryonic structures, Oocytes, Drosophila, Female, Mutant Proteins, Protein Multimerization, 030217 neurology & neurosurgery, Protein Binding, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f745a80df782d69dc130aa01c357b74Test
https://doi.org/10.1016/j.ydbio.2021.06.009Test -
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المؤلفون: Shaheen Akhtar, Joanna Bottomley, Edward Ryder, Daniel M Barrett, Michaela Bruntraeger, Sanger Mouse Genetics, James Bussell, Jonathan Burvill, Radka Platte, Debarati Sethi, Diane Gleeson
المصدر: Methods (San Diego, Calif.)
مصطلحات موضوعية: FASTQ format, Genotyping, Genotype, Genotyping Techniques, Mouse, Computational biology, Biology, Polymerase Chain Reaction, Genome, Article, General Biochemistry, Genetics and Molecular Biology, DNA sequencing, Mice, 03 medical and health sciences, PCR, polymerase chain reaction, Animals, CRISPR, CRISPR, clustered regularly interspaced short palindromic repeat, hom, homozygous, Allele, Molecular Biology, Alleles, QC, 030304 developmental biology, 0303 health sciences, fungi, 030302 biochemistry & molecular biology, sgRNA, single guide RNA, Mutant, food and beverages, High-Throughput Nucleotide Sequencing, NGS, next generation sequencing, het, heterozygous, Amplicon, WT, wild-type, Mice, Mutant Strains, QC, quality control, NHEJ, non-homologous end joining, NGS
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef79b367f901763da5e833510b51bcdcTest
https://doi.org/10.1016/j.ymeth.2020.10.011Test -
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المؤلفون: Hwei-Jen Lee, Yung-Lung Chang, Jen-Tzu Liu, Sheng-Peng Wu, Wei-Min Huang, Chi-Ching Hwang, Chih-Wei Huang, Kai-Ling Huang
المصدر: Biochemical Journal. 478:2201-2215
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, Mutant, Ligands, 010402 general chemistry, 4-Hydroxyphenylpyruvate Dioxygenase, 01 natural sciences, Biochemistry, Catalysis, Substrate Specificity, 03 medical and health sciences, Dioxygenase, Humans, Enzyme kinetics, Molecular Biology, 030304 developmental biology, Homogentisate 1,2-dioxygenase, 0303 health sciences, Chemistry, Substrate (chemistry), Cell Biology, Ligand (biochemistry), 0104 chemical sciences, Kinetics, Mutation, Helix, Mutant Proteins, 4-Hydroxyphenylpyruvate dioxygenase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7347fa7d84ea971add7315a8092678dTest
https://doi.org/10.1042/bcj20210005Test -
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المؤلفون: Ryo Miyamoto, Takashi Kumasaka, Shigeyuki Matsumoto, Tohru Kataoka, Takashi Kawamura, Mitsugu Araki, Fumi Shima, Haruka Taniguchi-Tamura, Chiemi Tsuda, Yasushi Okuno
المصدر: Biochemical and Biophysical Research Communications. 565:85-90
مصطلحات موضوعية: 0301 basic medicine, Mutant, Molecular Conformation, Biophysics, Guanosine, Oncogenic mutant, Crystal structure, Crystallography, X-Ray, medicine.disease_cause, Biochemistry, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Molecular dynamics, chemistry.chemical_compound, Residue (chemistry), 0302 clinical medicine, Molecular dynamics simulation, medicine, Humans, Molecular Biology, X-ray crystallography, Mutation, Chemistry, Cell Biology, State transition, 030104 developmental biology, 030220 oncology & carcinogenesis, Intramolecular force, Guanosine Triphosphate, Structural communication, Ras
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad871a0c14a241079777a22fba1d2f9Test
https://hdl.handle.net/20.500.14094/0100476443Test -
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المؤلفون: Paul Castellano, Arianna Horgan, Kyle Nunn, Xuyuan Kuang, Joyce Kong, Jennifer Jiang, Zhiqun Tan, Uttara Hardikar, Wei Dai
المصدر: Biochem Biophys Res Commun
مصطلحات موضوعية: 0301 basic medicine, Electron Microscope Tomography, Protein Folding, Huntingtin, Mutant huntingtin, Mutant, Biophysics, PC12 Cells, Biochemistry, Extracellular vesicles, Article, 03 medical and health sciences, 0302 clinical medicine, Correlative light and electron microscopy, Conditioned medium, Animals, Molecular Biology, Cryo-electron tomography, Huntingtin Protein, Microscopy, Chemistry, Cell Biology, Rats, Microscopy, Electron, Protein transmission, 030104 developmental biology, Culture Media, Conditioned, 030220 oncology & carcinogenesis, Liposomes, Mutation
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22b64cc819ab4536e80e724068ef7deTest
https://doi.org/10.1016/j.bbrc.2021.04.124Test -
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المؤلفون: Hong Yan, Mengxu Zhu, Debby D. Wang
المصدر: BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-13 (2021)
BMC Molecular and Cell Biologyمصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Genotype, Receptor, ErbB-2, Mutant, Geometric properties, Drug resistance, Molecular Dynamics Simulation, Receptor, IGF Type 1, 03 medical and health sciences, 0302 clinical medicine, Molecular dynamics (MD) simulations, medicine, Humans, Epidermal growth factor receptor, Molecular Biology, Protein Kinase Inhibitors, biology, QH573-671, Chemistry, Wild type, Cancer, Cell Biology, Proto-Oncogene Proteins c-met, medicine.disease, Epidermal growth factor receptor (EGFR), ErbB Receptors, Crosstalk (biology), 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, Cancer research, biology.protein, Signaling crosstalk, Mutant Proteins, Signal transduction, Cytology, Tyrosine kinase, EGFR signaling, Signal Transduction, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200076283f76b06da3ae47d3936f0648Test
https://doaj.org/article/72ff0c4962e545c9be5a7f5d28eacb98Test -
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المؤلفون: Adam J. Lawther, Haoyu Wu, Luke Isbel, Lucia Daxinger, Harald Oey, Matthew W. Hale, Lexie Prokopuk, Emma Whitelaw, Alex Spurling
المصدر: eLife, 5
eLife
eLife, Vol 5 (2016)مصطلحات موضوعية: 0301 basic medicine, CCCTC-Binding Factor, Chromatin Immunoprecipitation, Mouse, QH301-705.5, Science, Mutant, Kruppel-Like Transcription Factors, Protocadherin, Nerve Tissue Proteins, Biology, General Biochemistry, Genetics and Molecular Biology, Gene Knockout Techniques, Mice, 03 medical and health sciences, Cerebellum, Gene expression, Animals, momme, Epigenetics, Biology (General), Promoter Regions, Genetic, Transcription factor, Uncategorized, Mice, Knockout, Regulation of gene expression, Binding Sites, widely interspaced zinc finger motifs, Behavior, Animal, epigenetics, General Immunology and Microbiology, General Neuroscience, Promoter, Sequence Analysis, DNA, General Medicine, Molecular biology, 030104 developmental biology, Gene Expression Regulation, Genes and Chromosomes, Medicine, Chromatin immunoprecipitation, Protein Binding, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95403115a3669ca0b6197e7d6185c22Test
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المؤلفون: Shankar Mandal, Nils G. Walter, Alexander Johnson-Buck, Kunal Khanna
المصدر: Methods
مصطلحات موضوعية: Detection limit, 0303 health sciences, Total internal reflection fluorescence microscope, Chemistry, 030302 biochemistry & molecular biology, Mutant, Fluorescence, Article, General Biochemistry, Genetics and Molecular Biology, Kinetics, MicroRNAs, 03 medical and health sciences, Förster resonance energy transfer, Limit of Detection, Nucleic Acids, Intramolecular force, Fluorescence Resonance Energy Transfer, Nucleic acid, Biophysics, Nanotechnology, Molecule, Molecular Biology, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b204df6f5f144f19a66a5bf3ad3e08e0Test
https://doi.org/10.1016/j.ymeth.2021.06.014Test