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المؤلفون: Wen Liu, Xing Ye, Xiangwu Tang, Yan Liu, Ya-nan Bie, Yu-Guang Tian, Tao Xu, Hong-Quan Luo, Weiwang Gu, Chunjin Liang, Qin Yang, Peng Gu, Bangzhu Chen
المصدر: Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 530-547 (2021)
مصطلحات موضوعية: 0301 basic medicine, pig, lethal liver injury, Genetic enhancement, Mutant, HPD ablation, Biology, QH426-470, medicine.disease_cause, Tyrosinemia Type I, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, tyrosinemia type I, medicine, Genetics, metabolic reprogramming, oxidative stress, Molecular Biology, Gene, Liver injury, QH573-671, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, Fumarylacetoacetate hydrolase, Cytology, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b940b471e6fe30744c9032052beef8Test
http://www.sciencedirect.com/science/article/pii/S2329050121000681Test -
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المؤلفون: Zixu Zhu, Dandan Zhang, Jin-Long Qiu, Yanpeng Wang, Shengnan Li, Chao Sun, Dexing Lin, Guanwen Liu, Caixia Gao, Chenxiao Xue, Qiupeng Lin
المصدر: Journal of Genetics and Genomics. 48:444-451
مصطلحات موضوعية: CRISPR-Associated Proteins, Mutant, Computational biology, Genome, Homology (biology), 03 medical and health sciences, 0302 clinical medicine, Bacterial Proteins, INDEL Mutation, Genome editing, Genetics, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Indel, Molecular Biology, Triticum, 030304 developmental biology, Gene Editing, 0303 health sciences, Nuclease, Endodeoxyribonucleases, biology, Eubacterium, Protoplasts, food and beverages, RNA, Oryza, Plants, Genetically Modified, biology.protein, CRISPR-Cas Systems, Genome, Plant, 030217 neurology & neurosurgery, RNA, Guide, Kinetoplastida
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84a0ae8983e66f7fdf0482489eb5407Test
https://doi.org/10.1016/j.jgg.2021.04.003Test -
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المؤلفون: Hongyong Zhang, Chunwei Cao, Jianguo Zhao, Dengfeng Bi, Jing Yao, Shiming Yang, Weiwei Guo, Nan Zhang, Yu Wang, Yongshun Li, Yanfang Wang, Guosong Qin, Jin Zhang, Naipeng Hou, Ruigao Song
المصدر: Molecular Therapy: Nucleic Acids, Vol 24, Iss, Pp 986-999 (2021)
مصطلحات موضوعية: 0301 basic medicine, Genetic enhancement, Mutant, RM1-950, anophthalmia, Biology, Gene mutation, medicine.disease_cause, base editor, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, CRISPR, CRISPR/Cas9, hearing loss, MITF, Mutation, Waardenburg syndrome, Point mutation, medicine.disease, Microphthalmia-associated transcription factor, Molecular biology, 030104 developmental biology, gene correction, 030220 oncology & carcinogenesis, Molecular Medicine, Therapeutics. Pharmacology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b94e648ec75f2af695f370f6f569ffTest
https://doi.org/10.1016/j.omtn.2021.04.009Test -
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المؤلفون: Elizabeth K. Schmidt, Roberta A. Mittelstaedt, Timothy W. Robison, Xuefei Cao, Ying Chen, Wei Sun, Rebecca Wynne, Yiying Wang, Levan Muskhelishvili, Charles C. Valentine, Thomas H. Smith, Lindsey N. Williams, Zachary K Norgaard, Robert H. Heflich, Kelly Davis, Jesse J. Salk, Jeffry Yaplee
المصدر: Environmental and Molecular Mutagenesis
مصطلحات موضوعية: Ethyl methanesulfonate, Epidemiology, DNA damage, Health, Toxicology and Mutagenesis, Cell, Mutant, Respiratory System, 010501 environmental sciences, Biology, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, medicine, Humans, Genetics (clinical), Research Articles, 030304 developmental biology, 0105 earth and related environmental sciences, 0303 health sciences, Goblet cell, human in vitro air‐liquid‐interface (ALI) airway epithelial tissue model, Mutagenicity Tests, Mutagenesis, Epithelial Cells, respiratory system, Molecular biology, In vitro, medicine.anatomical_structure, chemistry, error‐corrected next generation sequencing (ecNGS), Ethyl Methanesulfonate, Toxicity, Mutation, ethyl methanesulfonate (EMS), Research Article, Mutagens
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2149b0742866ddafa9a6c2b7b5751dd5Test
http://europepmc.org/articles/PMC8251634Test -
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المؤلفون: Corrado Poggesi, Michael Regnier, Jennifer Davis, Momcilo Prodanovic, Michael A. Geeves, Joseph D. Powers, Srboljub M. Mijailovich
المصدر: Journal of Molecular and Cellular Cardiology
J Mol Cell Cardiolمصطلحات موضوعية: Models, Molecular, Sarcomeres, 0301 basic medicine, Myofilament, Mutant, Mice, Transgenic, 030204 cardiovascular system & hematology, Models, Biological, Sarcomere, Article, Troponin C, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Myofibrils, Troponin complex, Troponin I, medicine, Animals, Humans, Molecular Biology, Alleles, Actin, Chemistry, Cardiac muscle, Myocardial Contraction, QP, 030104 developmental biology, medicine.anatomical_structure, Mutation, Biophysics, Calcium, Cardiology and Cardiovascular Medicine, Algorithms, Biomarkers, Protein Binding
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5022f221e11372ffcd25a4ecd12d98e0Test
https://doi.org/10.1016/j.yjmcc.2021.02.009Test -
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المؤلفون: Ke Ding, Kaili Jiang, Xiaojuan Song, Shingpan Chan, Xia Tang, Zhang Zhang, Rui He, Xiaomei Ren, Zhengchao Tu, Yuting Wang, Jing Guo
المصدر: Cancer Medicine
Cancer Medicine, Vol 10, Iss 14, Pp 4874-4884 (2021)مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, V561F, Mutant, Apoptosis, Mice, SCID, Mice, 0302 clinical medicine, Phosphorylation, RC254-282, Original Research, Cancer Biology, ABL, Chemistry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Oncology, Fibroblast growth factor receptor, 030220 oncology & carcinogenesis, Benzamides, Morpholines, Antineoplastic Agents, Cell Line, resistance, 03 medical and health sciences, Inhibitory Concentration 50, In vivo, Quinoxalines, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 3, Radiology, Nuclear Medicine and imaging, Pyrroles, Receptor, Fibroblast Growth Factor, Type 4, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Fibroblast Growth Factor, Type 2, IC50, Cell Proliferation, GZD824, Fibroblast growth factor receptor 1, Phenylurea Compounds, Molecular biology, G1 Phase Cell Cycle Checkpoints, In vitro, stomatognathic diseases, 030104 developmental biology, FGFR1, Pyrimidines, Drug Resistance, Neoplasm, Mutation, Pyrazoles, Drug Screening Assays, Antitumor, Neoplasm Transplantation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562e8458e92c6535d08bed3c5d1bb7daTest
http://europepmc.org/articles/PMC8290231Test -
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المؤلفون: Zhenghu Chu, Xingwang Li, Changyin Wu, Xiaobin Liu, Jiali Shen, Junkai Zhu, Xiaodong Xin
المصدر: Journal of Genetics and Genomics. 48:485-496
مصطلحات موضوعية: Mutant, Flowers, MLH3, Biology, medicine.disease_cause, Interference (genetic), Chromosomes, Plant, 03 medical and health sciences, 0302 clinical medicine, Meiosis, Genetics, Homologous chromosome, medicine, Crossing Over, Genetic, Molecular Biology, Plant Proteins, 030304 developmental biology, 0303 health sciences, Mutation, Synapsis, Oryza, Cell biology, Chromosome Pairing, MutL Proteins, MutL Protein Homolog 1, Homologous recombination, 030217 neurology & neurosurgery, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636806983f743d64633f3daa2dff2b53Test
https://doi.org/10.1016/j.jgg.2021.04.011Test -
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المؤلفون: Yunjian Xu, Wenqing Zhou, Fang Liu, Xiaoyu Li, Bao Hui, Fei Hanting
المصدر: Biochemical and Biophysical Research Communications. 558:196-201
مصطلحات موضوعية: 0301 basic medicine, Transgene, Mutant, Arabidopsis, Biophysics, Flowers, Genes, Plant, Plant Roots, Zea mays, Biochemistry, Phosphates, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Gene Expression Regulation, Plant, Auxin, Phosphate Transport Proteins, Arabidopsis thaliana, Promoter Regions, Genetic, Molecular Biology, Gene, Plant Proteins, chemistry.chemical_classification, biology, fungi, Gene Expression Regulation, Developmental, food and beverages, Cell Biology, Plants, Genetically Modified, Phosphate, biology.organism_classification, Phenotype, Up-Regulation, Cell biology, Plant Leaves, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Mutation, Cell Division
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802bb32a313c681c396e047f917b13d2Test
https://doi.org/10.1016/j.bbrc.2020.09.039Test -
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المؤلفون: Haohang Sun, Ji Dai, Yulian Wu, Meidi Yan, Shuangshuang Zhang
المصدر: Biochemical and Biophysical Research Communications. 560:119-125
مصطلحات موضوعية: 0301 basic medicine, Carcinogenesis, Cell Survival, Mutant, Biophysics, SOD2, Apoptosis, Breast Neoplasms, Mice, SCID, medicine.disease_cause, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, medicine, Animals, Humans, Gene silencing, Neoplasm Invasiveness, Molecular Biology, Messenger RNA, Oncogene, Superoxide Dismutase, Chemistry, Cell Biology, Gene Expression Regulation, Neoplastic, MicroRNAs, 030104 developmental biology, Caspases, 030220 oncology & carcinogenesis, Cancer research, Female, RNA, Long Noncoding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03712b0e529a3a94ed8bb1f3cc2c6514Test
https://doi.org/10.1016/j.bbrc.2021.04.133Test -
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المؤلفون: Wenfeng Wang, Zinian Zhu, Bashan Zhang, Xueming Zhou, Beijing Luo, Aijiao Ding, Rong Li, Xibo Zhang
المصدر: Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-9 (2021)
Journal of Orthopaedic Surgery and Researchمصطلحات موضوعية: 0301 basic medicine, Mutant, Bone Morphogenetic Protein 2, Gene Expression, Diseases of the musculoskeletal system, medicine.disease_cause, 0302 clinical medicine, Gene expression, Medicine, Orthopedics and Sports Medicine, Cells, Cultured, beta Catenin, Orthopedic surgery, Mutation, biology, Osteoblast, Gene Expression Regulation, Developmental, Cell Differentiation, medicine.anatomical_structure, 030220 oncology & carcinogenesis, embryonic structures, Osteocalcin, Alkaline phosphatase, Osteogenesis imperfecta, Signal transduction, Research Article, Signal Transduction, animal structures, β-Catenin, Mutation, Missense, WNT1, Wnt1 Protein, Bone morphogenetic protein 2, 03 medical and health sciences, Humans, Glycogen Synthase Kinase 3 beta, Osteoblasts, business.industry, RANK Ligand, Alkaline Phosphatase, Molecular biology, 030104 developmental biology, RC925-935, biology.protein, Surgery, business, RD701-811
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065e86a89ab1bb96e7a77044915c259cTest
https://doaj.org/article/7bd3e1acdf9c4ea8a40fceb51a7ffe67Test