Cosmetic outcome as rated by patients, doctors, nurses and BCCT.core software assessed over 5 years in a subset of patients in the TARGIT-A Trial
| العنوان: | Cosmetic outcome as rated by patients, doctors, nurses and BCCT.core software assessed over 5 years in a subset of patients in the TARGIT-A Trial |
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| المؤلفون: | Anna K. Nowak, Jayant S. Vaidya, Norman R. Williams, David Joseph, Max Bulsara, Tammy Corica, Mandy Taylor, Mohammed Keshtgar, Christobel Saunders |
| المصدر: | Radiation Oncology (London, England) Radiation Oncology, Vol 13, Iss 1, Pp 1-10 (2018) |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | lcsh:Medical physics. Medical radiology. Nuclear medicine, Targeted Intraoperative Radiotherapy, medicine.medical_specialty, Esthetics, medicine.medical_treatment, lcsh:R895-920, Nurses, Breast Neoplasms, lcsh:RC254-282, 03 medical and health sciences, Intraoperative Period, 0302 clinical medicine, Cohen's kappa, Breast cancer, Physicians, Breast Cancer, Medicine, Humans, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, External beam radiotherapy, Generalized estimating equation, Radiation oncologist, Aged, TARGIT-IORT, Aged, 80 and over, Core (anatomy), Radiotherapy, business.industry, BCCT.core, Research, Cosmesis, Middle Aged, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, Radiation therapy, Treatment Outcome, Oncology, Patient Satisfaction, 030220 oncology & carcinogenesis, Physical therapy, External Beam Radiotherapy, Female, Cosmetic Rating Systems, business, Software |
| الوصف: | Background The purpose of this research was to assess agreement between four rating systems of cosmetic outcome measured in a subset of patients with early breast cancer participating in the randomised TARGIT-A trial. TARGIT-A compared risk-adapted single-dose intra-operative radiotherapy (TARGIT-IORT) to whole breast external beam radiotherapy (EBRT). Methods Patients, their Radiation Oncologist and Research Nurse completed a subjective cosmetic assessment questionnaire before radiotherapy and annually thereafter for five years. Objective data previously calculated by the validated BCCT.core software which utilizes digital photographs to score symmetry, colour and scar was also used. Agreement was assessed by the Kappa statistic and longitudinal changes were assessed by generalized estimating equations. Results Overall, an Excellent-Good (EG) cosmetic result was scored more often than a Fair-Poor (FP) result for both treatment groups across all time points, with patients who received TARGIT-IORT scoring EG more often than those who received EBRT however this was statistically significant at Year 5 only. There was modest agreement between the four rating systems with the highest Kappa score being moderate agreement which was between nurse and doctor scores at Year 1 with Kappa = 0.46 (p |
| تدمد: | 1748-717X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab5b28a211d8c884721b13605b3edd1Test https://pubmed.ncbi.nlm.nih.gov/29653541Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6ab5b28a211d8c884721b13605b3edd1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1748717X |
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