نتائج البحث - "Glucagon-Like Peptide-1 Receptor"

المساهمون: Medical Research Council (MRC), The Academy of Medical Sciences, Society for Endocrinology, European Foundation for the Study of Diabetes

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 37, Iss, Pp 100991-(2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Acylation, GLP-1RA, glucagon-like peptide-1 receptor agonist, Pharmacology, 0601 Biochemistry and Cell Biology, law.invention, Mice, 0302 clinical medicine, n.c., not calculable, law, Glucagon-Like Peptide 1, Receptors, Glucagon, Receptor, TR-FRET, time-resolved Förster resonance energy transfer, Trafficking, Chemistry, Type 2 diabetes, Ligand (biochemistry), Glucagon-like peptide-1, 3. Good health, cAMP, cyclic adenosine monophosphate, FITC, fluorescein isothiocyanate, Signal Transduction, lcsh:Internal medicine, PBS, phosphate-buffered saline, 030209 endocrinology & metabolism, T2D, type 2 diabetes, AUC, area under curve, Brief Communication, SEM, standard error of the mean, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, Pharmacokinetics, Confocal microscopy, In vivo, Potency, Animals, Humans, HTRF, homogenous time-resolved fluorescence, lcsh:RC31-1245, HBSS, Hank's buffered salt solution, Molecular Biology, Biased signalling, Dose-Response Relationship, Drug, Exendin-4, Cell Biology, DIO, diet-induced obesity, LC/MSMS, liquid chromatography/tandem mass spectrometry, 0606 Physiology, Peptide Fragments, 030104 developmental biology, Glucose, HEK293 Cells, Exenatide, Blood sugar regulation, BSA, bovine serum albumin, Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eea458e3c27345ef8e319b61a8f529fTest
https://pubmed.ncbi.nlm.nih.gov/32278079Test

6

Non-peptide agonists and positive allosteric modulators of glucagon-like peptide-1 receptors: Alternative approaches for treatment of Type 2 diabetes

المؤلفون: Faisal Malik, Zhijun Li

المصدر: Br J Pharmacol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880f0a41d4acf8f1be04a7995e786e68Test
https://pubmed.ncbi.nlm.nih.gov/33724441Test

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A GLP-1:CCK fusion peptide harnesses the synergistic effects on metabolism of CCK-1 and GLP-1 receptor agonism in mice

المؤلفون: James L. Trevaskis, Victor G. Howard, David C. Hornigold, Emma Roth, Stephanie Oldham, Matthew P. Coghlan, Sarah Will, Clemence Blouet

المساهمون: Blouet, Clemence [0000-0002-1752-1270], Apollo - University of Cambridge Repository

المصدر: Appetite

مصطلحات موضوعية: Male, 0301 basic medicine, Agonist, endocrine system, medicine.drug_class, 030209 endocrinology & metabolism, Peptide, Pharmacology, Glucagon-Like Peptide-1 Receptor, Article, Rats, Sprague-Dawley, Eating, Mice, 03 medical and health sciences, 0302 clinical medicine, Glucagon-Like Peptide 1, In vivo, Weight Loss, medicine, Animals, Obesity, Receptor, General Psychology, Glucagon-like peptide 1 receptor, Cholecystokinin, Mice, Knockout, chemistry.chemical_classification, Nutrition and Dietetics, digestive, oral, and skin physiology, Wild type, Brain, Drug Synergism, Metabolism, Receptor, Cholecystokinin A, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Anti-Obesity Agents, Peptides, hormones, hormone substitutes, and hormone antagonists

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aeb2017fb8104b2d5b1e6141972ede5Test
https://doi.org/10.1016/j.appet.2018.05.131Test

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The Effect of Exenatide Once Weekly on Carotid Atherosclerosis in Individuals With Type 2 Diabetes: An 18-Month Randomized Placebo-Controlled Study

المؤلفون: Peter D. Reaven, Keith C Chan, Raymond Q. Migrino, Juraj Koska, Kelly Cooper-Cox

المصدر: Diabetes Care

مصطلحات موضوعية: Blood Glucose, Carotid Artery Diseases, Cardiovascular and Metabolic Risk, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Placebo-controlled study, 030209 endocrinology & metabolism, Type 2 diabetes, Placebo, Cardiovascular System, Gastroenterology, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, 0302 clinical medicine, Glucagon-Like Peptide 1, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, 030212 general & internal medicine, Glycemic, Glycated Hemoglobin, Advanced and Specialized Nursing, Venoms, business.industry, medicine.disease, Clinical trial, Postprandial, Diabetes Mellitus, Type 2, Exenatide, Peptides, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b42a66d40bbbd250b4c20a25a370431Test
https://doi.org/10.2337/figshare.13281389Test

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Medication adherence to injectable glucagon-like peptide-1 (GLP-1) receptor agonists dosed once weekly vs once daily in patients with type 2 diabetes: A meta-analysis

المؤلفون: Jessica M Cannon, Matthew D Brock, Alyssa K Muraoka, Erin R. Weeda

المصدر: International journal of clinical practiceREFERENCES. 75(9)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227902c5209a33f4a52a50eea45289eaTest
https://pubmed.ncbi.nlm.nih.gov/33527605Test

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Sustained release of a GLP-1 and FGF21 dual agonist from an injectable depot protects mice from obesity and hyperglycemia

المؤلفون: Megan E. Capozzi, Caslin A. Gilroy, Anastasia K. Varanko, David A. D'Alessio, Jenny Tong, Ashutosh Chilkoti, Jonathan E. Campbell

المصدر: Science Advances

مصطلحات موضوعية: Agonist, endocrine system, FGF21, Combination therapy, medicine.drug_class, 030209 endocrinology & metabolism, Type 2 diabetes, Pharmacology, Glucagon-Like Peptide-1 Receptor, Diabetes Mellitus, Experimental, Mice, 03 medical and health sciences, Engineering, 0302 clinical medicine, Glucagon-Like Peptide 1, Weight loss, medicine, Animals, Humans, Health and Medicine, Obesity, Research Articles, 030304 developmental biology, Glycemic, 0303 health sciences, Multidisciplinary, business.industry, SciAdv r-articles, medicine.disease, Fibroblast Growth Factors, Diabetes Mellitus, Type 2, Delayed-Action Preparations, Hyperglycemia, medicine.symptom, Peptides, business, Linker, hormones, hormone substitutes, and hormone antagonists, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149abe5ec52a4b0d67342e0c03e89e88Test
https://doi.org/10.1126/sciadv.aaz9890Test

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