نتائج البحث - "Randy L. Johnson"

1

Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma

المصدر: Gut

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9075c7eb8e0bd0d26a8e7c400cb58bTest
https://doi.org/10.1136/gutjnl-2020-321175Test

2

YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression

المؤلفون: Claudio Punzo, Shan Ma, Randy L. Johnson, Y. Tony Ip, Kyvan Dang, Qi Li, Xu Wu, Junhao Mao, April Deng, Jennifer L. Cotton, Huapeng Li, Lihua Julie Zhu, Sun Yang

المصدر: Cell Reports, Vol 29, Iss 10, Pp 3200-3211.e4 (2019)
Cell reports

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Uveal Neoplasms, Cre recombinase, Cell Cycle Proteins, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Cell Line, Tumor, medicine, Animals, Humans, Protein kinase A, Melanoma, lcsh:QH301-705.5, Adaptor Proteins, Signal Transducing, Cell Proliferation, Kinase, YAP-Signaling Proteins, eye diseases, 030104 developmental biology, HEK293 Cells, lcsh:Biology (General), Tumor progression, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Mutation, Cancer research, Disease Progression, Trans-Activators, Melanocytes, Female, KRAS, sense organs, Signal transduction, Mitogen-Activated Protein Kinases, 030217 neurology & neurosurgery, GNAQ, Signal Transduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b88072644b027e5cc1a69d37baf5eeTest
http://www.sciencedirect.com/science/article/pii/S2211124719303286Test

3

Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response

المصدر: Gut

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, DNA Copy Number Variations, gastrointestinal cancer, T cell, cancer genetics, Antineoplastic Agents, Adenocarcinoma, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Immune system, Stomach Neoplasms, Chromosomal Instability, Exome Sequencing, medicine, Humans, Molecular Targeted Therapy, Exome, Peritoneal Neoplasms, Aged, Aged, 80 and over, Ploidies, biology, Gene Expression Profiling, gastric cancer, Stomach, Gastroenterology, DNA, Neoplasm, Middle Aged, Cell cycle, mutations, Phenotype, Immune checkpoint, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mutation, gene expression, Cancer research, biology.protein, Female, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145da6f1ddfcab67847260292cbaa027Test
https://doi.org/10.1136/gutjnl-2018-318070Test

4

Anti-osteogenic function of a LIM-homeodomain transcription factor LMX1B is essential to early patterning of the calvaria

المؤلفون: Asma Almaidhan, Nadine A. Darwiche, Veronica Choi, Jeffry M. Cesario, Randy L. Johnson, Lindsay J. Deacon, Jong Uk Chung, Krishnakali Dasgupta, Kesava Asam, Michael P. Khairallah, Juhee Jeong, Jimin Kim, André Landin Malt

المصدر: Developmental Biology. 443:103-116

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab456db402e770532f629c6bc4705262Test
https://doi.org/10.1016/j.ydbio.2018.05.022Test

5

Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors

المصدر: British Journal of Cancer

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Galectin 3, 0302 clinical medicine, Galectin-3, YAP1, Regulation of gene expression, therapeutic target, food and beverages, hemic and immune systems, Azepines, Blood Proteins, Prognosis, Phenotype, Up-Regulation, Gene Expression Regulation, Neoplastic, c-MYC, 030220 oncology & carcinogenesis, Female, medicine.medical_specialty, Cell Survival, Galectins, chemical and pharmacologic phenomena, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Downregulation and upregulation, Stomach Neoplasms, Cell Line, Tumor, Internal medicine, Biomarkers, Tumor, medicine, Humans, Adaptor Proteins, Signal Transducing, Cell Proliferation, Cell growth, business.industry, fungi, YAP-Signaling Proteins, Triazoles, Phosphoproteins, digestive system diseases, 030104 developmental biology, Ral GTP-Binding Proteins, Cell culture, Cancer research, ral GTP-Binding Proteins, gastric adenocarcinoma, Neoplasm Grading, Translational Therapeutics, business, prognostic marker, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58366773adcf8508a4cda98128d2c4dTest
https://doi.org/10.1038/bjc.2017.388Test

6

Tumor-associated macrophage infiltration is highly associated with PD-L1 expression in gastric adenocarcinoma

المؤلفون: Randy L. Johnson, Wayne L. Hofstetter, Arlene M. Correa, Shumei Song, Xiaochuan Dong, Akihiro Suzuki, Jaffer A. Ajani, Kazuto Harada, Zhenning Wang, Yan Xu, Koyu Suzuki, Hisashi Onodera, Kazuki Sudo, Jeannelyn S. Estrella

المصدر: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 21(1)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9d8aa502d88eeb3afbbc2cf4b9adc7Test
https://pubmed.ncbi.nlm.nih.gov/28801853Test

7

Hippo signaling suppresses cell ploidy and tumorigenesis through Skp2

المؤلفون: Suyuan Ji, Daming Gao, Chengyan Liu, Dawang Zhou, Qiao Wu, Keiko Nakayama, Jing Geng, Qiyuan Li, Lixin Hong, Shihao Zhang, Xianming Deng, Kwang Huei Lin, Keiichi I. Nakayama, Yuanyuan Zeng, Lanfen Chen, Qingxu Liu, Qinghua Chen, Weiji Zhang, Liang Zhu, Zhonglei Lu, Zhenyu Yin, Xiufeng Sun, Randy L. Johnson, Yuxi Li

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Time Factors, Cell, Cell Cycle Proteins, P300-CBP Transcription Factors, medicine.disease_cause, Mice, Cytosol, Pregnancy, p300-CBP Transcription Factors, S-Phase Kinase-Associated Proteins, Protein Stability, Liver Neoplasms, food and beverages, Acetylation, Forkhead Transcription Factors, Hep G2 Cells, Cell biology, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Cell Transformation, Neoplastic, Phenotype, Oncology, Hippo signaling, Female, RNA Interference, Signal transduction, Cyclin-Dependent Kinase Inhibitor p27, Signal Transduction, Carcinoma, Hepatocellular, Mice, Transgenic, Biology, Protein Serine-Threonine Kinases, Transfection, Article, 03 medical and health sciences, medicine, Animals, Humans, Genetic Predisposition to Disease, Hippo Signaling Pathway, Protein kinase B, Adaptor Proteins, Signal Transducing, Cell Proliferation, Hippo signaling pathway, Ploidies, Cell growth, fungi, Epistasis, Genetic, YAP-Signaling Proteins, Phosphoproteins, 030104 developmental biology, Proteolysis, Cancer research, Carcinogenesis, Proto-Oncogene Proteins c-akt, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b749080e45476fc11c8cb09259ba2aTest
https://europepmc.org/articles/PMC5863541Test/

8

Inactivation of Hippo Pathway Is Significantly Associated with Poor Prognosis in Hepatocellular Carcinoma

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 22(5)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, MST1, Carcinoma, Hepatocellular, Kaplan-Meier Estimate, Protein Serine-Threonine Kinases, Bioinformatics, Disease-Free Survival, Article, 03 medical and health sciences, Mice, Cell Line, Tumor, Gene expression, Carcinoma, Biomarkers, Tumor, Medicine, Animals, Humans, Clinical significance, Hippo Signaling Pathway, Adaptor Proteins, Signal Transducing, Aged, Regulation of gene expression, Aged, 80 and over, Hippo signaling pathway, business.industry, Liver Neoplasms, Intracellular Signaling Peptides and Proteins, Cancer, YAP-Signaling Proteins, Middle Aged, medicine.disease, Phosphoproteins, Prognosis, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, Hepatocellular carcinoma, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Cancer research, Trans-Activators, Female, business, Signal Transduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5968e466986866f6ccb4cbacdcc2f9Test
https://pubmed.ncbi.nlm.nih.gov/26459179Test

9

Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma

المصدر: Hepatology (Baltimore, Md.). 63(1)

مصطلحات موضوعية: 0301 basic medicine, Carcinoma, Hepatocellular, Amino Acid Transport Systems, mTORC1, Biology, Mechanistic Target of Rapamycin Complex 1, medicine.disease_cause, Article, 03 medical and health sciences, Mice, medicine, Animals, Humans, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, YAP1, chemistry.chemical_classification, Hippo signaling pathway, Hepatology, TOR Serine-Threonine Kinases, Liver Neoplasms, Intracellular Signaling Peptides and Proteins, YAP-Signaling Proteins, Phosphoproteins, Cell biology, Amino acid, Solute carrier family, Protein Structure, Tertiary, Gene Expression Regulation, Neoplastic, 030104 developmental biology, chemistry, Biochemistry, Multiprotein Complexes, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Trans-Activators, Female, Carcinogenesis, Signal Transduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a1af19596cf379bf8273f114dcb80cTest
https://pubmed.ncbi.nlm.nih.gov/26389641Test

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