Heterologous vaccine effects
| العنوان: | Heterologous vaccine effects |
|---|---|
| المؤلفون: | Peter Aaby, Ofer Levy, Jacques Louis, Frank Shann, Michael Greenberg, William H. Warren, Mihai G. Netea, Mitra Saadatian-Elahi, Valentina Picot |
| المصدر: | Vaccine, 34, 34, pp. 3923-30 Vaccine, 34, 3923-30 |
| بيانات النشر: | Elsevier BV, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Systems biology, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Biology, Immunity, Heterologous, Vaccines, Attenuated, 03 medical and health sciences, medicine, Humans, Regulatory science, Attenuated vaccine, Heterologous vaccine, General Veterinary, General Immunology and Microbiology, Public health, Public Health, Environmental and Occupational Health, Congresses as Topic, Expert group, Immunity, Innate, Vaccination, 030104 developmental biology, Infectious Diseases, Vaccines, Inactivated, Immunology, Molecular Medicine, Engineering ethics, France, Immunologic Memory |
| الوصف: | Item does not contain fulltext The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important biological process by a growing group of immunologists and epidemiologists. Much remain to be learned about the extent and underlying mechanisms for these effects. The conference "Off-target effects of vaccination" held in Annecy-France (June 8-10 2015) intended to take a holistic approach drawing from the fields of immunology, systems biology, epidemiology, bioinformatics, public health and regulatory science to address fundamental questions of immunological mechanisms, as well as translational questions about vaccines NSEs. NSE observations were examined using case-studies on live attenuated vaccines and non-live vaccines followed by discussion of studies of possible biological mechanisms. Some possible pathways forward in the study of vaccines NSE were identified and discussed by the expert group. |
| تدمد: | 0264-410X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f779dc2c6185c859964d348e7a82185Test https://doi.org/10.1016/j.vaccine.2016.06.020Test |
| حقوق: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....4f779dc2c6185c859964d348e7a82185 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 0264410X |
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