المؤلفون: Rita Mendes, Catarina Brito, Megan C. Cox, Inês A. Isidro, Kathleen Halwachs, Fernanda Silva, Julie J Purkal, Adelyn L Zelaya-Lazo, Ana Félix, Erwin R. Boghaert, Teresa F. Mendes

المساهمون: Instituto de Tecnologia Química e Biológica António Xavier (ITQB), Centro de Estudos de Doenças Crónicas (CEDOC), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Cancer microenvironment, Science, Drug development, Antineoplastic Agents, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Lactate dehydrogenase, Cell Line, Tumor, Neoplasms, Spheroids, Cellular, Drug Discovery, Tumor Cells, Cultured, Medicine, Animals, Humans, General, Cancer models, 030304 developmental biology, 0303 health sciences, Multidisciplinary, L-Lactate Dehydrogenase, business.industry, Culture growth, 3. Good health, Clinical trial, chemistry, 030220 oncology & carcinogenesis, Cancer research, Drug Screening Assays, Antitumor, business, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8ac81b3c771941eb41563f083c9b56Test
https://doaj.org/article/6ba6021cf4734f4ebc89722a5ae55c02Test

المؤلفون: Xiangxiang Meng, Zetao Liu, Shaobo Yao, Haiwen Bie, Mingyou Yuan

المصدر: Histochemistry and Cell Biology. 156:227-237

مصطلحات موضوعية: Male, 0301 basic medicine, Histology, Lactate dehydrogenase A, Biology, Cell Line, Mice, 03 medical and health sciences, Transactivation, Transcription (biology), Forkhead box Q1, Transcriptional regulation, medicine, Animals, education, Molecular Biology, Transcription factor, Mice, Knockout, education.field_of_study, Sertoli Cells, 030102 biochemistry & molecular biology, Gene targeting, Forkhead Transcription Factors, Cell Biology, Sertoli cell, Cell biology, Medical Laboratory Technology, 030104 developmental biology, medicine.anatomical_structure, Lactates, Lactate Dehydrogenase 5

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5262e03ef5157024966b5a2d33d1fa8Test
https://doi.org/10.1007/s00418-021-01994-xTest

المؤلفون: Mohamed K. Abdel-Rafei, Noura M Thabet, Nermeen M El Bakary, Ghada El Tawill, Khaled Shaaban Azab, Neama M El Fatih

المصدر: Journal of Radiation Research

مصطلحات موضوعية: Necrosis, Antioxidant, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Fucoxanthin, Xanthophylls, Kidney, Antioxidants, chemistry.chemical_compound, Mice, 0302 clinical medicine, chemistry.chemical_classification, 0303 health sciences, Apelin Receptors, Radiation, Glutathione peroxidase, NF-kappa B, Apelin-13/APJ, Malondialdehyde, Oxidants, Apelin, medicine.anatomical_structure, Liver, Matrix Metalloproteinase 9, Organ Specificity, 030220 oncology & carcinogenesis, Intercellular Signaling Peptides and Proteins, Matrix Metalloproteinase 2, medicine.symptom, MMP-9, Whole-Body Irradiation, Signal Transduction, medicine.medical_specialty, α-7nAchR, 03 medical and health sciences, Lactate dehydrogenase, Internal medicine, medicine, Animals, Radiology, Nuclear Medicine and imaging, Fundamental Radiation Science, 030304 developmental biology, Inflammation, Tissue Inhibitor of Metalloproteinase-1, L-Lactate Dehydrogenase, Monocyte, Glutathione, γ-radiation, Endocrinology, chemistry, Gamma Rays, AcademicSubjects/SCI00960, AcademicSubjects/MED00870

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30214c17e6d8f3108e2b41351abd16bTest
http://europepmc.org/articles/PMC8273792Test

المؤلفون: Philip L. Lorenzi, Wuhao Lu, Meng Cui, Xiangdong Le, Yunyun Chen, Anastasios Maniakas, Lin Tan, Vlad C. Sandulache, Keith A. Michel, Stephen Y. Lai, Nagireddy Putluri, Abdallah S.R. Mohamed, Joshua S. Niedzielski, James A. Bankson, Collin J. Harlan, Ying C. Henderson

المصدر: Br J Cancer

مصطلحات موضوعية: Cancer Research, Lactate dehydrogenase A, Down-Regulation, Mice, Nude, Context (language use), Gene Expression Regulation, Enzymologic, Article, Small hairpin RNA, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Lactate dehydrogenase, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Metabolomics, Glycolysis, Molecular Targeted Therapy, Enzyme Inhibitors, RNA, Small Interfering, education, education.field_of_study, L-Lactate Dehydrogenase, Squamous Cell Carcinoma of Head and Neck, Chemistry, medicine.disease, Xenograft Model Antitumor Assays, Head and neck squamous-cell carcinoma, Gene Expression Regulation, Neoplastic, Oncology, Head and Neck Neoplasms, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer research, Feasibility Studies, Female, Reprogramming, Algorithms, Intracellular

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb89361b349a5c507df84525a5db944Test
https://doi.org/10.1038/s41416-021-01297-xTest

المؤلفون: Noemí Gómez-Lado, Manuel Macia, Efigenia Arias, Anxo Martinez-Ordoñez, Noemi Eiro, Tomás García-Caballero, Fabio Pereira, Samuel Seoane, Pablo Aguiar, Leandro Avila, Roman Perez-Fernandez, Francisco J. Vizoso

المساهمون: Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Ciencias Forenses, Anatomía Patolóxica, Xinecoloxía e Obstetricia, e Pediatría, Universidade de Santiago de Compostela. Departamento de Ciencias Morfolóxicas, Universidade de Santiago de Compostela. Departamento de Fisioloxía

المصدر: Oncogene
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lactate dehydrogenase A, Mice, Nude, Biology, Transfection, Article, Mice, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, Immune system, Genetics, medicine, Animals, Humans, education, Molecular Biology, Transcription factor, Mice, Inbred BALB C, Gene knockdown, education.field_of_study, L-Lactate Dehydrogenase, Cancer, Cellular Reprogramming, medicine.disease, Mechanisms of disease, 030104 developmental biology, Anaerobic glycolysis, 030220 oncology & carcinogenesis, Cancer cell, Disease Progression, MCF-7 Cells, Cancer research, Heterografts, Transcription Factor Pit-1

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a358d1462b424fffacaaaf3dad9744f0Test
https://doi.org/10.1038/s41388-021-01740-6Test

المؤلفون: Lingmei Qian, Zijie Cheng, Bing Zhang, Li Zhang, Mengwen Feng, Xuejun Wang, Jingjing Ding, Hao Zhang

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Male, STAT3 Transcription Factor, Cell Survival, myocardial I/R, Apoptosis, Myocardial Reperfusion Injury, Pharmacology, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Fibrosis, Lactate dehydrogenase, Troponin I, medicine, Animals, Myocytes, Cardiac, Viability assay, EIP‐22, STAT3, Cells, Cultured, chemistry.chemical_classification, Membrane Potential, Mitochondrial, Reactive oxygen species, TUNEL assay, biology, L-Lactate Dehydrogenase, JAK2/STAT3, Cell Biology, Original Articles, Janus Kinase 2, Tyrphostins, medicine.disease, peptide, Rats, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Original Article, Peptides, Reactive Oxygen Species, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada0c392ff34497ba4ef0e8063bcc90fTest
http://europepmc.org/articles/PMC8034444Test

المؤلفون: Kaneez Fatima, Abha Meena, Suaib Luqman, Nusrat Masood, Zahoor Ahmad Wani

المصدر: Journal of Advanced Research

مصطلحات موضوعية: TRIG, Triglyceraldehyde, Skin Neoplasms, Cell, DOXO, Doxorubicin, Hyaluronidase, Pharmacology, NaOH, Sodium hydroxide, Polymerization, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, BIL, Bilirubin total & direct, Neomenthol, PEP A, pepstatin A, Cancer biomarker, MEF, Mean erythrocyte fragility, HYAL, Hyaluronidase, PBS, Phosphate buffer saline, CM-H2DCFDA, Chloromethyl derivative of dichloro fluorescin diacetate, HA, Hyaluronic acid, Epidermoid carcinoma, Human epidermoid carcinoma, 030220 oncology & carcinogenesis, RBC, Red blood cell, DMEM, Dulbecco’s minimal essential media, SRB, Sulphorhodamine B, BUN, Blood urea nitrogen, FACS, Fluorescence-Activated Cell Sorting, AKLP, Alkaline phosphatase, Hyaluronoglucosaminidase, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, TMPD, N,N,N′,N′-tetramethyl-p-phenylenediamine, Article, 03 medical and health sciences, In vivo, Ehrlich Ascites Carcinoma, BE, Binding energy, Humans, CATD, Cathepsin D, LDH, Lactate dehydrogenase, COX-2, Cyclooxygenase 2, FOX, Ferrous oxidation-xylenol orange, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, In vitro, Ab/Am, Antibiotic/antimycotic, NRU, Neutral red uptake, EC50, Half maximal effective concentration, 030104 developmental biology, IC50, Half maximal inhibitory concentration, EAC, Ehlrich Ascites Carcinoma, RPMI, Roswell park memorial institute, ROS, Reactive oxygen species, 0301 basic medicine, HDL, High density lipoprotein, TNBS, Trinitrobenzenesulphonic acid, PI3K, Phosphotidyl inositol-3 kinase, URIC, Uric acid, DNA, Deoxyribonucleic acid, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid, Tubulin, OECD, Organization for Economic Co-operation and Development, SGPT, Alanine aminotransferase, LOX-5, Lipoxygenase-5, DFMO, α-difluoro methyl ornithine, Multidisciplinary, WBC, White blood cell, Chemistry, ELISA, enzyme-linked immunosorbent assay, PKB/Akt, Protein kinase B, AA, Arachidonic acid, RNase A, Ribonuclease A, TPR, Total protein, Molecular Docking Simulation, medicine.anatomical_structure, TCA, Tricarboxylic acid, CHOL, Cholesterol, Ki, Inhibitory constant, medicine.drug, ODC, Ornithine decarboxylase, DHFR, Dihydrofolatereductase, BSA, Bovine serum albumin, PDB, Protein Data Bank, medicine, Animals, MMP, Mitochondrial membrane potential, DCFDA, 2′,7′ dichloro fluorescin diacetate, RNA, Ribonucleic acid, RIPA, Radio immune precipitation assay buffer, EDTA, Ethylene diamine tetra acetic acid, IC50, TPA, 12-O-Tetradecanoylphorbol-13-acetate, ComputingMethodologies_COMPUTERGRAPHICS, TRPM8, Transient receptor potential member 8, Cell Proliferation, HDAC, Histone deacetylase, MTX, Methotrexate, OF, Osmotic fragility, PI, Propidium iodide, FDA, Food and Drug Administration, HEK293 Cells, PDT, Podophyllotoxin, Cell culture, NAC, N-acetyl cysteine, SGOT, Aspartate aminotransferase, CRTN, Creatinine, FBS, Fetal bovine serum, PCR, Polymerase chain reaction, Rh123, Rhodamine 123, Ex vivo, IDT, Integrated DNA Technologies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7618e7dc6e2d535e1930d5f8c2bf7d7eTest
https://doi.org/10.1016/j.jare.2021.06.003Test

المؤلفون: Yimeng Cui, Yue Cui, Ying Song, Ying Xing, Yaowen Cui, Shi Yan, Li Cai, Fanglin Tian, Xin Wang, Mengru Cao, Xiuwen Lan, Jian Huang, Dexin Jia

المصدر: Cancer Letters. 520:12-25

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Vesicular Transport Proteins, Proto-Oncogene Proteins c-myc, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, In vivo, Carcinoma, Non-Small-Cell Lung, Positron Emission Tomography Computed Tomography, Warburg Effect, Oncologic, Animals, Humans, Glycolysis, Wnt Signaling Pathway, beta Catenin, Cell Proliferation, Gene knockdown, L-Lactate Dehydrogenase, Microarray analysis techniques, Chemistry, Wnt signaling pathway, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 14-3-3 Proteins, Oncology, Gluconeogenesis, A549 Cells, Anaerobic glycolysis, 030220 oncology & carcinogenesis, Catenin, Cancer research, Heterografts, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb4af7d2481ec282960df850bd56d93Test
https://doi.org/10.1016/j.canlet.2021.06.023Test

المؤلفون: Bowen Gao, Weidong Zhang, Yanfeng Wu, Huiyong Shen, Yangbai Sun, Fengfeng Li, Mengjun Ma, Sanhong Liu, Yuhang Jiang, Meng Chen

المصدر: Theranostics

مصطلحات موضوعية: 0301 basic medicine, Jumonji Domain-Containing Histone Demethylases, Lung Neoplasms, Cell, Mice, Nude, Medicine (miscellaneous), Bone Neoplasms, LDHA, Biology, Metastasis, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Histone demethylation, Cell Movement, In vivo, Cell Line, Tumor, Lactate dehydrogenase, medicine, Animals, Humans, KDM6B, Molecular Targeted Therapy, Precision Medicine, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Osteosarcoma, L-Lactate Dehydrogenase, Cell migration, Benzazepines, Prognosis, medicine.disease, Xenograft Model Antitumor Assays, Up-Regulation, Histone Code, Pyrimidines, Lung metastasis, 030104 developmental biology, medicine.anatomical_structure, Real-time polymerase chain reaction, chemistry, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer research, H3K27me3 demethylation, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3e18f7ec254eb7663021f8f7473dfaTest
https://doi.org/10.7150/thno.53347Test

المؤلفون: Michelle Khai Khun Yap, Jia Jin Hiu

المصدر: International Journal of Biological Macromolecules. 184:776-786

مصطلحات موضوعية: Proteomics, Programmed cell death, Cell Membrane Permeability, Time Factors, Cell Survival, Necroptosis, Breast Neoplasms, Venom, 02 engineering and technology, medicine.disease_cause, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Tandem Mass Spectrometry, Structural Biology, Lactate dehydrogenase, medicine, Animals, Humans, Cobra Neurotoxin Proteins, Molecular Biology, 030304 developmental biology, Elapid Venoms, 0303 health sciences, Dose-Response Relationship, Drug, Toxin, Naja, General Medicine, Metabolism, 021001 nanoscience & nanotechnology, Molecular biology, Gene Expression Regulation, Neoplastic, chemistry, MCF-7, Apoptosis, MCF-7 Cells, Female, 0210 nano-technology, Chromatography, Liquid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb36fa614ee30c276ee69b80e995532bTest
https://doi.org/10.1016/j.ijbiomac.2021.06.145Test