نتائج البحث

1

HIF-1α inhibits mitochondria-mediated apoptosis and improves the survival of human adipose-derived stem cells in ischemic microenvironments

المؤلفون: Hao Wu, Tianqi Lv, Jiayi Xu, Giorgi Oganezov, Hao Pang, Jie Wang, Xiaoqun Dong, Ying Liu, Jiaxu Li, Yongting Zhou, Zhibo Xiao

المصدر: Journal of Plastic, Reconstructive & Aesthetic Surgery. 74:1908-1918

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e573a53bb25a6eabb01b7e66f94501Test
https://doi.org/10.1016/j.bjps.2020.11.041Test

2

The RNA‐binding protein SORBS2 suppresses hepatocellular carcinoma tumourigenesis and metastasis by stabilizing RORA mRNA

المؤلفون: Lili Han, Chen Huang, Shuqun Zhang

المصدر: Liver International. 39:2190-2203

مصطلحات موضوعية: Adult, Male, Carcinoma, Hepatocellular, Epithelial-Mesenchymal Transition, Carcinogenesis, Retinoic acid, Mice, Nude, RNA-binding protein, Biology, Flow cytometry, Metastasis, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Western blot, Cell Movement, Cell Line, Tumor, medicine, Animals, Humans, RNA, Messenger, Neoplasm Metastasis, 3' Untranslated Regions, Adaptor Proteins, Signal Transducing, Cell Proliferation, Neoplasm Staging, Messenger RNA, Hepatology, medicine.diagnostic_test, Cell growth, Liver Neoplasms, RNA-Binding Proteins, Nuclear Receptor Subfamily 1, Group F, Member 1, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, digestive system diseases, Gene Expression Regulation, Neoplastic, Disease Models, Animal, chemistry, 030220 oncology & carcinogenesis, Cancer research, Immunohistochemistry, Female, RNA Interference, 030211 gastroenterology & hepatology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a351c65239393e2bea3aa0c5b912c21Test
https://doi.org/10.1111/liv.14202Test

3

On the relationship between VDR, RORα and RORγ receptors expression and HIF1‐α levels in human melanomas

المؤلفون: Anton M. Jetten, Andrzej Slominski, Wojciech Jóźwicki, Anna A. Brożyna

المصدر: Exp Dermatol

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Skin Neoplasms, Retinoic acid, Dermatology, Biology, T-Lymphocytes, Regulatory, Biochemistry, Calcitriol receptor, Article, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, CYP24A1, medicine, Humans, Single-Blind Method, Lymphocytes, Vitamin D3 24-Hydroxylase, Receptor, Melanoma, Molecular Biology, Aged, 25-Hydroxyvitamin D3 1-alpha-Hydroxylase, Aged, 80 and over, Cell Nucleus, Orphan receptor, FOXP3, Nuclear Receptor Subfamily 1, Group F, Member 1, Middle Aged, Nuclear Receptor Subfamily 1, Group F, Member 3, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Cell Hypoxia, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, 030104 developmental biology, chemistry, Nuclear receptor, Cancer research, Receptors, Calcitriol, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3aa44913d2ff840a9108510f572a732Test
https://doi.org/10.1111/exd.14002Test

4

Phase 1 trial of ADI-PEG20 plus cisplatin in patients with pretreated metastatic melanoma or other advanced solid malignancies

المؤلفون: Sapna Pradyuman Patel, David S. Hong, Vivek Subbiah, Amanda Johnston, Siqing Fu, John S. Bomalaski, Sarina Anne Piha-Paul, Shuyang Yao, Ahmed Kaseb, Aung Naing, Nai Shi, Filip Janku, Apostolia Maria Tsimberidou, Shannon N. Westin, John Stewart

المصدر: Br J Cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d35421e6155a20aeb943eeead2c5143Test
https://doi.org/10.1038/s41416-020-01230-8Test

5

Randomized clinical trial of pembrolizumab vs chemotherapy for previously untreated Chinese patients with PD‐L1‐positive locally advanced or metastatic non–small‐cell lung cancer: KEYNOTE‐042 China Study

المؤلفون: Yi‐Long Wu, Li Zhang, Yun Fan, JianYing Zhou, Qing Zhou, Wei Li, ChengPing Hu, GongYan Chen, Xin Zhang, CaiCun Zhou, Thao Dang, Sara Sadowski, Debra A. Kush, Yu Zhou, Ben Li, Tony Mok

المصدر: International Journal of Cancer

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, China, Lung Neoplasms, non–small‐cell lung cancer, medicine.medical_treatment, Short Report, Pembrolizumab, chemotherapy, Antibodies, Monoclonal, Humanized, PD-L1 Positive, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Lung cancer, Cancer Therapy and Prevention, Aged, Chemotherapy, business.industry, Hazard ratio, Middle Aged, medicine.disease, Carboplatin, Pemetrexed, chemistry, programmed death ligand 1, 030220 oncology & carcinogenesis, Female, pembrolizumab, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d738eb6422851bd45d601d057c69c71bTest
http://europepmc.org/articles/PMC8048589Test

6

Safety and pharmacokinetics of polatuzumab vedotin in Japanese patients with relapsed/refractory B-cell non-Hodgkin lymphoma: a phase 1 dose-escalation study

المؤلفون: Yukari Hida, Kensei Tobinai, Kiyohiko Hatake, Tomohiro Kinoshita, Tomohisa Saito, Dai Maruyama, Shinichi Makita, Yasuhito Terui, Satsuki Murakami, Kazuhito Yamamoto, Yusuke Higuchi, Masahiro Yokoyama

المصدر: Japanese Journal of Clinical Oncology

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Immunoconjugates, phase 1 clinical trial, Follicular lymphoma, Phases of clinical research, polatuzumab vedotin, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Recurrence, Internal medicine, medicine, Humans, AcademicSubjects/MED00300, Radiology, Nuclear Medicine and imaging, B-cell lymphoma, Lymphoma, Follicular, Aged, business.industry, Antibodies, Monoclonal, General Medicine, Middle Aged, medicine.disease, Polatuzumab vedotin, 030104 developmental biology, Oncology, Tolerability, Monomethyl auristatin E, chemistry, 030220 oncology & carcinogenesis, Female, Original Article, Lymphoma, Large B-Cell, Diffuse, business, pharmacokinetics, Diffuse large B-cell lymphoma, Blood sampling

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d92325fce02686f88fa74dfbce5e17Test
https://doi.org/10.1093/jjco/hyaa169Test

7

Synergistic effect of ibrutinib and CD19 CAR‐T cells on Raji cells in vivo and in vitro

المؤلفون: Yanyu Jiang, Q Deng, Rui Zhang, Lei Sun, Juan Mu, Meijing Liu, Zheng Li, Xuelin Wang

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, programmed cell death‐ligand 1, T-Lymphocytes, Chronic lymphocytic leukemia, Cell, Immunotherapy, Adoptive, Mice, chemistry.chemical_compound, Basic and Clinical Immunology, Raji cell line, 0302 clinical medicine, Piperidines, hemic and lymphatic diseases, chimeric antigen receptor, medicine.diagnostic_test, biology, Chemistry, General Medicine, Middle Aged, Combined Modality Therapy, Raji cell, Treatment Outcome, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Ibrutinib, Original Article, Female, Lymphoma, Large B-Cell, Diffuse, Adult, STAT3 Transcription Factor, Antigens, CD19, Receptors, Antigen, T-Cell, Bruton tyrosine kinase inhibitor, CD19, Immunophenotyping, Flow cytometry, 03 medical and health sciences, In vivo, Cell Line, Tumor, Biomarkers, Tumor, medicine, tumor microenvironment, Animals, Humans, Protein Kinase Inhibitors, Aged, Neoplasm Staging, Tumor microenvironment, Adenine, Original Articles, medicine.disease, Xenograft Model Antitumor Assays, Disease Models, Animal, 030104 developmental biology, biology.protein, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49d2425f68eed7413004c23fbb5d00bTest
https://doi.org/10.1111/cas.14638Test

8

Role of DNA methylation on human CTSG in dermatomyositic myoideum

المؤلفون: Ying Liang, Yue Peng, Xiaofeng Sun

المصدر: Cell Biology International. 44:2409-2415

مصطلحات موضوعية: Adult, DNA (Cytosine-5-)-Methyltransferase 1, Male, 0301 basic medicine, China, Cathepsin G, DNMT3B, Gene Expression, Biology, Dermatomyositis, Cell Line, DNA Methyltransferase 3A, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Transcription (biology), Humans, DNA (Cytosine-5-)-Methyltransferases, Epigenetics, Promoter Regions, Genetic, NF-kappa B, Cell Biology, General Medicine, DNA Methylation, Chromatin, 030104 developmental biology, Gene Expression Regulation, chemistry, CpG site, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, DNMT1, Cytokines, CpG Islands, Female, I-kappa B Proteins, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07628687cb55e11089e760cb921e5677Test
https://doi.org/10.1002/cbin.11447Test

9

Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-2100

المؤلفون: Satoshi Yamashita, Naoko Hattori, Yuki Kurahashi, Toshikazu Ushijima, Naoko Sueoka-Aragane, Tatsuro Watanabe, Akemi Sato, Kensuke Kojima, Hideaki Nakamura, Atsushi Kawaguchi, Shinya Kimura, Eisaburo Sueoka, Nao Yoshida, Kazuharu Kamachi, Seiji Okada, Hiroshi Ureshino, Yuki Fukuda-Kurahashi

المصدر: Blood. 136:871-884

مصطلحات موضوعية: Adult, 0301 basic medicine, Pyridines, viruses, Immunology, Administration, Oral, Decitabine, Antineoplastic Agents, Biology, Biochemistry, Mice, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, medicine, Animals, Humans, Leukemia-Lymphoma, Adult T-Cell, Molecular Targeted Therapy, Cells, Cultured, Aged, Mice, Knockout, Regulation of gene expression, Human T-lymphotropic virus 1, Mice, Inbred BALB C, Gene Expression Regulation, Leukemic, Cell growth, T-cell receptor, Drugs, Investigational, Cell Biology, Hematology, DNA Methylation, Cell Transformation, Viral, HTLV-I Infections, Xenograft Model Antitumor Assays, Demethylation, Demethylating agent, 030104 developmental biology, chemistry, Cell culture, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, Female, medicine.drug, DNA hypomethylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f0e7224c117c25f69a987a740a43e5Test
https://doi.org/10.1182/blood.2019003084Test

10

DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility

المؤلفون: Sheng Wei, Huan Guo, Xiaomin Zhang, Yue Feng, Mengying Li, Meian He, Hang Li, Hua Meng, Yansen Bai, Guyanan Li, Yangkai Li, Wei Wei

المصدر: Cancer Medicine
Cancer Medicine, Vol 10, Iss 11, Pp 3770-3781 (2021)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Lung Neoplasms, Gene Expression, Body Mass Index, Epigenesis, Genetic, LMNA, chemistry.chemical_compound, Epigenome, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, RC254-282, ATP Binding Cassette Transporter, Subfamily G, Member 1, Original Research, DNA methylation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Methylation, Middle Aged, Lamin Type A, 030220 oncology & carcinogenesis, genome‐wide methylation association study, Female, Sterol Regulatory Element Binding Protein 1, Cancer Prevention, Adult, non‐small cell lung cancer, medicine.medical_specialty, Mediation (statistics), China, 03 medical and health sciences, BMI, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Genetic Predisposition to Disease, Epigenetics, mediation analysis, Aged, business.industry, Lung cancer susceptibility, 030104 developmental biology, chemistry, Trans-Activators, CpG Islands, business, Body mass index, DNA, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f62a8ad1354597e6a8983f9d6a88a5Test
https://pubmed.ncbi.nlm.nih.gov/33939316Test

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