المؤلفون: Ruoli Bai, Roberta Bortolozzi, Virginia Spanò, Antonio Palumbo Piccionello, Alessandra Montalbano, Ernest Hamel, Paola Barraja, Maria Valeria Raimondi, Roberta Rocca, Stefano Alcaro, Giampietro Viola, Marilia Barreca, Anna Carbone

المساهمون: Spano' V., Barreca M., Rocca R., Bortolozzi R., Bai R., Carbone A., Raimondi M.V., Palumbo Piccionello A., Montalbano A., Alcaro S., Hamel E., Viola G., Barraja P.

المصدر: European Journal of Medicinal Chemistry. 212:113122

مصطلحات موضوعية: Models, Molecular, Cell cycle checkpoint, Isoindoles, Apoptosis, 01 natural sciences, Polymerization, Tubulin Polymerization Inhibitors, Cell cycle arrest, HeLa, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Tubulin, Drug Discovery, Humans, Tubulin polymerization inhibitors, 030304 developmental biology, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, 3]thiazolo[4, Organic Chemistry, General Medicine, biology.organism_classification, Tubulin Modulators, 0104 chemical sciences, Biochemistry, chemistry, Cell culture, 5-e]isoindoles, 1,3]thiazolo[4,5-e]isoindoles, Lead compound, Derivative (chemistry), HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd729e4101f14e38886f05dc1dd984e7Test
https://doi.org/10.1016/j.ejmech.2020.113122Test

المؤلفون: Ernest Hamel, Ruoli Bai, Giampietro Viola, Alessandra Locatelli, Alberto Leoni, Andrea Brancale, Federica Maccarinelli, Mirella Rambaldi, Elena Mattiuzzo, Roberta Bortolozzi, Roberto Ronca, Rita Morigi

المساهمون: Morigi, R., Locatelli, A., Leoni, A., Rambaldi, M., Bortolozzi, R., Mattiuzzo, E., Ronca, R., Maccarinelli, F., Hamel, E., Bai, R., Brancale, A., Viola, G.

مصطلحات موضوعية: Indoles, Apoptosis, Chemistry Techniques, Synthetic, 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones, Antiproliferative, Antitumor, Synthesis, Antineoplastic Agents, Caspase 3, Caspase 9, Cell Proliferation, Down-Regulation, Drug Screening Assays, Antitumor, Enzyme Activation, G2 Phase, HeLa Cells, Humans, Mitochondria, Structure-Activity Relationship, Drug Screening Assays, 01 natural sciences, HeLa, Drug Discovery, Pharmacology, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Cytotoxic T cell, 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones, Antiproliferative, Antitumor, Apoptosis, Synthesis, 0303 health sciences, biology, Chemistry, General Medicine, 3-(5-imidazo[2, 03 medical and health sciences, In vivo, medicine, 1-b]thiazolylmethylene)-2-indolinones, Structure–activity relationship, 030304 developmental biology, 010405 organic chemistry, Cell growth, Synthetic, Cancer, Chemistry Techniques, medicine.disease, biology.organism_classification, In vitro, 0104 chemical sciences, Cancer research

وصف الملف: application/pdf; STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abf8900d0de3edc82b98ef040c01800Test