دورية أكاديمية
State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1
| العنوان: | State of lipid peroxidation - antioxidant system in men with diabetes mellitus type 1 |
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| المؤلفون: | L. V. Belenkaya, L. F. Sholokhov, M. A. Darenskaya, I. M. Mikhalevich |
| المصدر: | Acta Biomedica Scientifica, Vol 1, Iss 3(2), Pp 12-15 (2016) |
| بيانات النشر: | Scientific Сentre for Family Health and Human Reproduction Problems |
| سنة النشر: | 2016 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | сахарный диабет 1-го типа, мужчины, перекисное окисление липидов, антиоксидантная система, Science |
| الوصف: | The aim of study is to assess lipid peroxidation and antioxidant system in men with diabetes mellitus type 1. The objective of this study was to identify features of the lipid peroxidation-antioxidant defense system in men of reproductive age with diabetes mellitus type 1. 22 men with diabetes mellitus type 1 (the average age of 27.1 ± 7.38years) and30 healthy men of the same age (control group) (the average age of 28.0 ± 4.3 years) were involved in the study. The main and control groups were formed on the principle of "copy - pair". Standard clinical examination methods were used: history taking, physical examination and consultation of specialists to identify complications of diabetes. To determine the indicators of the system of free-radical lipid oxidation and activity of antioxidant protection, the spectrophotometric and fluorometric methods were used. In men with diabetes mellitus 1 type, there is increase in the level of active products reacting with thiobarbituric acid compared to the same indicator in the control group. The level of antioxidant protection in men with diabetes mellitus 1 type unlike the control was characterized by decrease in total antioxidant activity. However, stability of processes of superoxide dismutase activity and the glutathione system in comparison with control is observed against the backdrop of intensity increase of oxidative processes. Activation of lipid peroxidation is observed in men with diabetes mellitus type 1. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Russian |
| تدمد: | 2541-9420 2587-9596 |
| العلاقة: | https://www.actabiomedica.ru/jour/article/view/177Test; https://doaj.org/toc/2541-9420Test; https://doaj.org/toc/2587-9596Test; https://doaj.org/article/b13153900b7741e48777fbc10f6626abTest |
| DOI: | 10.12737/article_590823a40a10b5.33824132 |
| الإتاحة: | https://doi.org/10.12737/article_590823a40a10b5.33824132Test https://doaj.org/article/b13153900b7741e48777fbc10f6626abTest |
| رقم الانضمام: | edsbas.F1B5889E |
| قاعدة البيانات: | BASE |
| تدمد: | 25419420 25879596 |
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| DOI: | 10.12737/article_590823a40a10b5.33824132 |