المؤلفون: Surace, Laura, Doisne, Jean-Marc, Croft, Carys, A, Thaller, Anna, Escoll, Pedro, Marie, Solenne, Petrosemoli, Natalia, Guillemot, Vincent, Dardalhon, Valerie, Topazio, Davide, Cama, Antonia, Buchrieser, Carmen, Taylor, Naomi, Amit, Ido, Musumeci, Olimpia, Di Santo, James, P

المساهمون: Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), École Doctorale Bio Sorbonne Paris Cité Paris (ED562 - BioSPC), Université Sorbonne Paris Cité (USPC)-Université Paris Cité (UPCité), Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria, Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Department of Otolaryngology, Ospedale “Giuseppe Mazzini” di Teramo, Department of Maxillofacial and Otolaryngology, Hospital "Floraspe Renzetti", Department of Immunology Rehovot, Israël, Weizmann Institute of Science Rehovot, Israël, Department of Clinical and Experimental Medicine Messina, Italy, University of Messina, The Innate Immunity Unit is supported by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur, the Agence National pour le Recherche (ANR) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (695467, ILC_REACTIVITY). A.T. is supported by European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement no. 765104. C.B.’s group was supported by the Fondation pour la Recherche Médicale (FRM) grant no. EQU201903007847 and the grant no. ANR-10-LABX-62-IBEID. L.S. was supported by an SNSF-Early PostDoc. Mobility fellowship and a Marie Curie grant (H2020- MSCA-IF-2017)., We thank all the members of the Innate Immunity Unit for helpful discussions, the Centre de Recherche Translationnelle and the logistic department of Institut Pasteur. We thank the CB-UTechS platform for cytometry support and the Imagopole-CiTech (part of France-BioImaging supported by ANR grant no. ANR-10-INSB-04-01, Conseil de la Region Ile-de-France, FRM) for technical support., The study was conceptualized by L.S. and J.P.D. Experiments were coordinated by L.S. FACS and subsequent analyses were performed by L.S., C.A.C., A.T., J.-M.D. and S.M. Confocal microscopy analysis was performed by P.E., C.B. and L.S. Bioinformatic analyses were performed by N.P. and V.G. RNA-seq experiments were conducted by I.A. O.M., V.D., N.T., D.T. and A.C. provided resources. L.S. and J.P.D. wrote the paper. Funding was acquired by L.S. and J.P.D., and the study was supervised by J.P.D., ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016), European Project: 765104,MATURE-NK, European Project: 796004,BIF-SCV

المصدر: ISSN: 1529-2908.

مصطلحات موضوعية: MESH: Amino Acids, Branched-Chain, MESH: Arginine, MESH: Cytokines, MESH: Energy Metabolism, MESH: Humans, MESH: Immunity, Innate, MESH: Interleukin-33, MESH: Lymphocyte Activation, MESH: Mitochondria, MESH: Mitochondrial Diseases, MESH: Phenotype, MESH: Th2 Cells, MESH: Case-Control Studies, MESH: Cell Proliferation, MESH: Cells, Cultured, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34686862; info:eu-repo/grantAgreement//695467/EU/Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease/ILC_REACTIVITY; info:eu-repo/grantAgreement//765104/EU/MAnufacturing of TUmour-REactive Natural Killer cells/MATURE-NK; info:eu-repo/grantAgreement//796004/EU/H2020-MSCA-IF-2017 Bifurcations in several complex variables/BIF-SCV; pasteur-03499188; https://pasteur.hal.science/pasteur-03499188Test; https://pasteur.hal.science/pasteur-03499188/documentTest; https://pasteur.hal.science/pasteur-03499188/file/2021_Nat%20Immunol_Surace.pdfTest; PUBMED: 34686862; PUBMEDCENTRAL: PMC8553616

الإتاحة: https://doi.org/10.1038/s41590-021-01043-8Test
https://pasteur.hal.science/pasteur-03499188Test
https://pasteur.hal.science/pasteur-03499188/documentTest
https://pasteur.hal.science/pasteur-03499188/file/2021_Nat%20Immunol_Surace.pdfTest

المؤلفون: Vanderkerken, Matthias, Baptista, Antonio, P., de Giovanni, Marco, Fukuyama, Satoshi, Browaeys, Robin, Scott, Charlotte, L., Norris, Paula, S., Eberl, Gerard, Di Santo, James, P., Vivier, Eric, Saeys, Yvan, Hammad, Hamida, Cyster, Jason, G., Ware, Carl, F., Tumanov, Alexei, V., de Trez, Carl, Lambrecht, Bart, N.

المساهمون: VIB-UGent Center for Inflammation Research Gand, Belgique (IRC), VIB Belgium, Universiteit Gent = Ghent University (UGENT), University of California San Francisco (UC San Francisco), University of California (UC), The University of Tokyo (UTokyo), Sanford Burnham Prebys Medical Discovery Institute, Microenvironnement et Immunité - Microenvironment and Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunité Innée - Innate Immunity, Innate Pharma, Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of Texas Health Science Center, The University of Texas Health Science Center at Houston (UTHealth), Vrije Universiteit Brussel (VUB), Erasmus University Medical Center Rotterdam (Erasmus MC), M. Vanderkerken is supported by a fellowship from Fonds Wetenschappelijk Onderzoek Vlaanderen, A.P. Baptista is supported by a Marie-Sklodowska Curie Action fellowship as part of Horizon 2020, C.L. Scott is supported by the Fonds Wetenschappelijk Onderzoek Vlaanderen and a European Research Council starting grant, Y. Saeys is supported by the Fonds Wetenschappelijk Onderzoek Vlaanderen and the Marylou Ingram Scholar program, H. Hammad is supported by a research initiative grant from Ghent University, A.V. Tumanov is supported by grants from the National Institutes of Health (AI135574) and the Max and Minnie Tomerlin Voelcker Fund, and B.N. Lambrecht is supported by a European Research Council advanced grant, a research initiative grant from Ghent University, and an Excellence of Science research grant.

المصدر: ISSN: 0022-1007.

مصطلحات موضوعية: [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33724364; pasteur-03258252; https://pasteur.hal.science/pasteur-03258252Test; https://pasteur.hal.science/pasteur-03258252/documentTest; https://pasteur.hal.science/pasteur-03258252/file/jem_20190835.pdfTest; PUBMED: 33724364; PUBMEDCENTRAL: PMC7970251

الإتاحة: https://doi.org/10.1084/jem.20190835Test
https://pasteur.hal.science/pasteur-03258252Test
https://pasteur.hal.science/pasteur-03258252/documentTest
https://pasteur.hal.science/pasteur-03258252/file/jem_20190835.pdfTest

المؤلفون: Guenin-Macé, Laure, Morel, Jean-David, Doisne, Jean-Marc, Schiavo, Angèle, Boulet, Lysiane, Mayau, Véronique, Goncalves, Pedro, Duchatelet, Sabine, Hovnanian, Alain, Bondet, Vincent, Duffy, Darragh, Ungeheuer, Marie-Noëlle, Delage, Maïa, Nassif, Aude, Di Santo, James, P., Demangel, Caroline

المساهمون: Immunobiologie de l'Infection - Immunobiology of Infection, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Sorbonne Paris Cité (USPC), École normale supérieure de Lyon (ENS de Lyon), Immunité Innée - Innate Immunity, Biochimie Hormonale et Nutritionnelle, Université Joseph Fourier - Grenoble 1 (UJF)-Centre Hospitalier Universitaire CHU Grenoble (CHUGA), Genetic skin diseases : from disease mechanism to therapies (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Service de Génétique Médicale CHU Necker, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Immunobiologie des Cellules dendritiques, Investigation Clinique et d’Accès aux Ressources Biologiques (Plate-forme) - Clinical Investigation and Access to BioResources (ICAReB), Institut Pasteur Paris (IP), Centre Médical de l'Institut Pasteur (CMIP), This study was supported by Institut Pasteur (to CD and JPDS) via the Center for Translational Science, INSERM (U1221, to CD, U1223, to JPDS), and “Société Française de Dermatologie” (to AN). The Biomics Platform, C2RT, Institut Pasteur is supported by France Génomique (ANR-10-INBS-09-09) and IBISA., We thank Armanda Casrouge for assistance in performing the immunostaining of skin biopsies, Olivier Join-Lambert for fruitful discussions on the skin microbiota of patients with HS, and Harry Sokol for his critical reading of this manuscript. We also thank Valérie Briolat and Laurence Motreff of the Biomics Wet-Lab Platform for 16S rRNA sequencing and the Image Analysis Hub for immunofluorescence data processing., ANR-10-INBS-0009,France Génomique,Organisation et montée en puissance d'une Infrastructure Nationale de Génomique(2010)

المصدر: ISSN: 2379-3708 ; JCI Insight ; https://pasteur.hal.science/pasteur-02983317Test ; JCI Insight, 2020, 5 (20), pp.e140598. ⟨10.1172/jci.insight.140598⟩.

مصطلحات موضوعية: Amino acid metabolism, Cellular immune response, Dermatology, Inflammation, Skin, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32970636; pasteur-02983317; https://pasteur.hal.science/pasteur-02983317Test; https://pasteur.hal.science/pasteur-02983317/documentTest; https://pasteur.hal.science/pasteur-02983317/file/140598.2-20201007112112-covered-253bed37ca4c1ab43d105aefdf7b5536.pdfTest; PUBMED: 32970636; PUBMEDCENTRAL: PMC7605522

الإتاحة: https://doi.org/10.1172/jci.insight.140598Test
https://pasteur.hal.science/pasteur-02983317Test
https://pasteur.hal.science/pasteur-02983317/documentTest
https://pasteur.hal.science/pasteur-02983317/file/140598.2-20201007112112-covered-253bed37ca4c1ab43d105aefdf7b5536.pdfTest

المؤلفون: de Cevins, Camille, Luka, Marine, Smith, Nikaïa, Meynier, Sonia, Magérus, Aude, Carbone, Francesco, García-Paredes, Víctor, Barnabei, Laura, Batignes, Maxime, Boullé, Alexandre, Stolzenberg, Marie-Claude, Pérot, Brieuc, P., Charbit, Bruno, Fali, Tinhinane, Pirabarakan, Vithura, Sorin, Boris, Riller, Quentin, Abdessalem, Ghaith, Beretta, Maxime, Grzelak, Ludivine, Goncalves, Pedro, Di Santo, James, P., Mouquet, Hugo, Schwartz, Olivier, Zarhrate, Mohammed, Parisot, Mélanie, Bole-Feysot, Christine, Masson, Cécile, Cagnard, Nicolas, Corneau, Aurélien, Bruneau, Camille, Zhang, Shen-Ying, Casanova, Jean-Laurent, Meunier, Brigitte Bader, Haroche, Julien, Melki, Isabelle, Lorrot, Mathie, Oualha, Mehdi, Moulin, Florence, Bonnet, Damien, Belhadjer, Zahra, Leruez, Marianne, Allali, Slimane, Leguen, Christèle Gras, de Pontual, Loïc, Fischer, Alain, Duffy, Darragh, Laucat, Fredéric Rieux-, Toubiana, Julie, Ménager, Mickaël, M.

المساهمون: Inflammatory Responses and Transcriptomic Networks in diseases (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Sanofi Aventis R&D Chilly-Mazarin, Immunologie Translationnelle - Translational Immunology lab, Institut Pasteur Paris (IP), Immunogenetics of pediatric autoimmune diseases (Equipe Inserm U1163), Cytometrie et Biomarqueurs – Cytometry and Biomarkers (UTechS CB), Immunologie humorale - Humoral Immunology, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Virus et Immunité - Virus and immunity (CNRS-UMR3569), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Immunité Innée - Innate Immunity, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Structure Fédérative de Recherche Necker (UAR 3633 / US24), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Cytométrie Pitié-Salpêtrière (PASS-CYPS), Unité Mixte de Service Production et Analyse de données en Sciences de la vie et en Santé (PASS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Human genetics of infectious diseases : Mendelian predisposition (Equipe Inserm U1163), Rockefeller University New York, Service d'immuno-hématologie pédiatrique CHU Necker, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), AP-HP Hôpital universitaire Robert-Debré Paris, CHU Trousseau APHP, Département des urgences pédiatriques CHU Necker, Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Laboratoire de Virologie CHU Necker, Département de Pédiatrie et maladies infectieuses CHU Necker, Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Service de Pédiatrie Jean Verdier, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Jean Verdier AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Sorbonne Paris Nord, Collège de France (CdF (institution)), Biodiversité et Epidémiologie des Bactéries pathogènes - Biodiversity and Epidemiology of Bacterial Pathogens, The study was supported by the Institut National de la Santé et de la Recherche Médicale (INSERM), by the “URGENCE COVID-19” fundraising campaign of Institut Pasteur, by the Atip-Avenir, Emergence ville de Paris program and fond de dotation Janssen Horizon and by government grants managed by the Agence National de la Recherche as part of the “Investment for the Future” program (Institut Hospitalo-Universitaire Imagine, grant ANR-10-IAHU-01, Recherche Hospitalo-Universitaire, grant ANR-18-RHUS-0010, Laboratoire d’Excellence ‘‘Milieu Intérieur”, grant ANR-10-LABX-69-01), the Centre de Référence Déficits Immunitaires Héréditaires (CEREDIH), the Agence National de la Recherche (ANR-flash Covid19 “AIROCovid” to FRL and “CoVarImm” to DD and JDS), and by the FAST Foundation (French Friends of Sheba Tel Hashomer Hospital). The LabTech Single Cell@Imagine is supported by the Paris Region and the “Investissements d’avenir” program through the 2019 ATF funding – Sésame Filières PIA (Grant N°3877871). CdC is the recipient of a CIFRE-PhD (Sanofi). L.B. was a recipient of an Imagine institute PhD international program supported by the Fondation Bettencourt Schueller. L.B. was also supported by the EUR G.E.N.E. (reference #ANR-17-EURE-0013) and is part of the Université de Paris IdEx #ANR-18-IDEX-0001 funded by the French Government through its “Investments for the Future” program. S.M. was a recipient of an INSERM and Institut Imagine post-doctorat program supported by the Fondation pour la Recherche Médicale (FRM N°SPF20170938825). NS was a recipient of the Pasteur-Roux-Cantarini Fellowship. VGP obtained an Imagine international PhD fellowship program supported by the Fondation Bettencourt Schueller. BPP is the recipient of an ANRS post-doctoral fellowship., ANR-10-IAHU-0001,Imagine,Institut Hospitalo-Universitaire Imagine(2010), ANR-18-RHUS-0010,ATRACTION,Autoimmunity/inflammation Through Rnaseq Analysis at the single Cell level for Therapeutic Innovation(2018), ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010), ANR-20-COVI-0022,AIROCovid19,Analyse Omics de la réponse immune aigue au cours de l'infection à Covid19: rationnel moléculaire pour un traitement ciblé(2020), ANR-17-EURE-0013,GENE,Génétique et Epigénétique Nouvelle Ecole(2017), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018)

المصدر: https://pasteur.hal.science/pasteur-03244400Test ; 2021.

مصطلحات موضوعية: [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: pasteur-03244400; https://pasteur.hal.science/pasteur-03244400Test; https://pasteur.hal.science/pasteur-03244400/documentTest; https://pasteur.hal.science/pasteur-03244400/file/2021.02.23.432486v1.full.pdfTest; BIORXIV: 2021.02.23.432486

الإتاحة: https://doi.org/10.1101/2021.02.23.432486Test
https://pasteur.hal.science/pasteur-03244400Test
https://pasteur.hal.science/pasteur-03244400/documentTest
https://pasteur.hal.science/pasteur-03244400/file/2021.02.23.432486v1.full.pdfTest

المؤلفون: Xu, Wei, Cherrier, Dylan, E, Chea, Sylvestre, Vosshenrich, Christian A. J., Serafini, Nicolas, Petit, Maxime, Liu, Pentao, Golub, Rachel, Di Santo, James, P.

المساهمون: Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Fudan University Shanghai, Université Paris Diderot - Paris 7 (UPD7), Lymphopoïèse (Lymphopoïèse (UMR_1223 / U1223 / U-Pasteur_4)), Institut Pasteur Paris (IP)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), The University of Hong Kong (HKU), D.E.C. is supported by the French Ministry of Higher Education, Research and Innovation. The Innate Immunity Unit is supported by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur, the Agence National pour le Recherche (ANR), and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (695467 – ILC_REACTIVITY), We thank Albert Bendelac for providing Zbtb16GFPCre mice, Andreas Diefenbach for providing Id2GFP mice, and Ana Cumano for providing OP9 and OP9-DL4 cells. We are grateful to Francina Langa-Vives and Franck Bourgade for their help with the generation of Id2RFP mice and the CB-UTechS platform for cytometry support. We thank all the members of the Innate Immunity Unit for helpful discussions., European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016)

المصدر: ISSN: 1074-7613 ; Immunity ; https://pasteur.hal.science/pasteur-02118991Test ; Immunity, 2019, 50 (4), pp.1054-1068.e3. ⟨10.1016/j.immuni.2019.02.022⟩.

مصطلحات موضوعية: lymphocyte, innate immunity, differentiation, transcription factor, cell fate, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30926235; info:eu-repo/grantAgreement//695467/EU/Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease/ILC_REACTIVITY; pasteur-02118991; https://pasteur.hal.science/pasteur-02118991Test; https://pasteur.hal.science/pasteur-02118991/documentTest; https://pasteur.hal.science/pasteur-02118991/file/1-s2.0-S1074761319300895-main.pdfTest; PUBMED: 30926235; PUBMEDCENTRAL: PMC6477155

الإتاحة: https://doi.org/10.1016/j.immuni.2019.02.022Test
https://pasteur.hal.science/pasteur-02118991Test
https://pasteur.hal.science/pasteur-02118991/documentTest
https://pasteur.hal.science/pasteur-02118991/file/1-s2.0-S1074761319300895-main.pdfTest

المؤلفون: Disson, Olivier, Bleriot, Camille, Jacob, Jean-Marie, Serafini, Nicolas, Dulauroy, Sophie, Jouvion, Grégory, Fevre, Cindy, Gessain, Grégoire, Thouvenot, Pierre, Eberl, Gérard, Di Santo, James, P., Peduto, Lucie, Lecuit, Marc

المساهمون: Biologie des Infections - Biology of Infection, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Stroma, inflammation et réparation tissulaire - Stroma, Inflammation and Tissue Repair, Immunité Innée - Innate Immunity, Microenvironnement et Immunité - Microenvironment and Immunity, Histopathologie humaine et Modèles animaux, Institut Pasteur Paris (IP), Université Paris Descartes - Paris 5 (UPD5), Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), This work was financed by Institut Pasteur, Institut National de la Santé et de la Recherche Médicale, Institut Carnot Pasteur Microbes et Santé, LabEx IBEID, the European Research Council grant Invadis, and the Agence Nationale de Recherche Organolist., We thank the members of the Biology of Infection Unit for their support. We thank Hélène Bierne for her implication in the initial phase of the project, Elena Tomasello and Eric Vivier for helpful discussions, Stéphane Dallongeville for image analysis, Sascha Cording, Morgane Lavina for technical help, and Hana Kammoun for critical reading. We thank Edith Gouin and Pascale Cossart for anti-Lm antibodies, Tracy Putoczki for Il11ra1−/− mice, Richard Flavell for Il22−/− mice, Bernhard Ryffel for IL23p19−/− mice, Laure Dumoutier, Jean-Christophe Renauld for anti–IL-22 antibody, and Gunnar C. Hansson for anti-MUC2C3 serum, ANR-15-CE15-0007,OrganoList,Interactions entre Listeria monocytogenes et la barrière intestinale(2015), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 681829,ERC-CoG-2015,INVADIS(2016)

المصدر: ISSN: 0022-1007.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio], [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30355616; info:eu-repo/grantAgreement//681829/EU/Microbial invasion and dissemination within the host, mechanisms and effects/INVADIS; pasteur-02142521; https://pasteur.hal.science/pasteur-02142521Test; https://pasteur.hal.science/pasteur-02142521/documentTest; https://pasteur.hal.science/pasteur-02142521/file/JEM_20181210.pdfTest; PUBMED: 30355616; PUBMEDCENTRAL: PMC6219733

الإتاحة: https://doi.org/10.1084/jem.20181210Test
https://pasteur.hal.science/pasteur-02142521Test
https://pasteur.hal.science/pasteur-02142521/documentTest
https://pasteur.hal.science/pasteur-02142521/file/JEM_20181210.pdfTest

المؤلفون: Vivier, Eric, Artis, David, Colonna, Marco, Diefenbach, Andreas, Di Santo, James, P., Eberl, Gerard, Koyasu, Shigeo, Locksley, Richard, M, Mckenzie, Andrew, N J, Mebius, Reina, E, Powrie, Fiona, Spits, Hergen

المساهمون: Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Innate Pharma, Cornell University New York, Washington University in Saint Louis (WUSTL), Charité - UniversitätsMedizin = Charité - University Hospital Berlin, Berlin Institute of Health (BIH), Deutsches Rheuma-ForschungsZentrum, Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Microenvironnement et Immunité - Microenvironment and Immunity, RIKEN Center for Integrative Medical Sciences Yokohama (RIKEN IMS), RIKEN - Institute of Physical and Chemical Research Japon (RIKEN), Keio University School of Medicine Tokyo, Japan, University of California San Francisco (UC San Francisco), University of California (UC), Medical Research Council, Vrije Universiteit Amsterdam Amsterdam (VU), University of Oxford, University of Amsterdam Amsterdam = Universiteit van Amsterdam (UvA), Research in the Artis lab is supported by the NIH, the Crohn's and Colitis Foundation, the Burroughs Wellcome Fund, the Cure for IBD, and the Jill Roberts Institute. M.C. is supported by the US NIH (UO1 AI095542, RO1 DE025884, and RO1 DK103039).The Diefenbach laboratory is supported by the European Research Council (ERC) (311377 - NUTRIMMUNE), the Priority Program 1937 “Innate Lymphoid Cells” of the Deutsche Forschungsgemeinschaft (DFG), the Einstein Foundation Berlin, and the Berlin Institute of Health. The Eberl lab is supported by grants from ANR, FRM, CCFA, Rainin Foundation and the Institut Pasteur. Research in the Koyasu laboratory is supported by a Grant-in-Aid for Scientific Research (A) (16H02631). Research in the Locksley laboratory is supported by the HHMI, the NIH, and the SABRE Center at UCSF. Research in the McKenzie laboratory is supported by funding from the MRC (U105178805) and the Wellcome Trust (100963/Z/13/Z). The Di Santo laboratory receives grants from the Institut Pasteur, Inserm, the Agence Nationale de la Recherche, the Ligue Nationale contre le Cancer, and the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Program (695467 - ILC_REACTIVITY). The Spits lab is supported by an advanced ERC grant (341038-AsthmaVir). Research in the Vivier laboratory is supported by funding from the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Program (694502-TILC), the Agence Nationale de la Recherche, Equipe Labellisée “La Ligue,”Ligue Nationale contre le Cancer, MSDAvenir, and Innate Pharma and institutional grants to the CIML (INSERM, CNRS, and Aix-Marseille University) and Marseille Immunopôle., We thank the members of all our laboratories for critically reading the manuscript, Adeline Crinier for help with Table 1, Linda Quatrini and Sophie Ugolini (CIML) for sharing unpublished results, and Marie-Alice Rarivoson (Innate-Pharma) for help in formatting the manuscript., European Project: 311377,EC:FP7:ERC,ERC-2012-StG_20111109,NUTRIMMUNE(2013), European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016), European Project: 341038,EC:FP7:ERC,ERC-2013-ADG,ASTHMAVIR(2014), European Project: 694502,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,TILC(2017)

المصدر: ISSN: 0092-8674.

مصطلحات موضوعية: tissue remodeling, plasticity, neuro-immunology, metabolism, innate lymphoid cells, immunity, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30142344; info:eu-repo/grantAgreement/EC/FP7/311377/EU/NutrImmune: Nutrient-controlled molecular pathways instructing development and function of mucosa-associated innate lymphocytes/NUTRIMMUNE; info:eu-repo/grantAgreement//695467/EU/Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease/ILC_REACTIVITY; info:eu-repo/grantAgreement/EC/FP7/341038/EU/The roles of innate lymphoid cells and rhinovirus in asthma exacerbations/ASTHMAVIR; info:eu-repo/grantAgreement//694502/EU/Targeting Innate Lymphoid Cells/TILC; pasteur-02101002; https://pasteur.hal.science/pasteur-02101002Test; PUBMED: 30142344

الإتاحة: https://doi.org/10.1016/j.cell.2018.07.017Test
https://pasteur.hal.science/pasteur-02101002Test

المؤلفون: Cherrier, Dylan, E, Serafini, Nicolas, Di Santo, James, P.

المساهمون: Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot - Paris 7 (UPD7), The Di Santo laboratory is supported by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur, the Agence National pour le Recherche (ANR), and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (695467 – ILC_REACTIVITY)., The authors would like to thank members of the Di Santo laboratory for helpful discussions., European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016)

المصدر: ISSN: 1074-7613 ; Immunity ; https://pasteur.hal.science/pasteur-02100997Test ; Immunity, 2018, 48 (6), pp.1091-1103. ⟨10.1016/j.immuni.2018.05.010⟩.

مصطلحات موضوعية: MESH: Animals, MESH: Cell Differentiation, MESH: Humans, MESH: Immunity, Innate, MESH: Killer Cells, Natural, MESH: Lymphocytes, MESH: T-Lymphocytes, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29924975; info:eu-repo/grantAgreement//695467/EU/Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease/ILC_REACTIVITY; pasteur-02100997; https://pasteur.hal.science/pasteur-02100997Test; https://pasteur.hal.science/pasteur-02100997/documentTest; https://pasteur.hal.science/pasteur-02100997/file/Cherrier_2018_Immunity_post-print.pdfTest; PUBMED: 29924975

الإتاحة: https://doi.org/10.1016/j.immuni.2018.05.010Test
https://pasteur.hal.science/pasteur-02100997Test
https://pasteur.hal.science/pasteur-02100997/documentTest
https://pasteur.hal.science/pasteur-02100997/file/Cherrier_2018_Immunity_post-print.pdfTest

المؤلفون: Berger, Cedric, N, Crepin, Valerie, F, Roumeliotis, Theodoros, Wright, James, C, Serafini, Nicolas, Pevsner-Fischer, Meirav, Yu, Lu, Elinav, Eran, Di Santo, James, P, Choudhary, Jyoti, S, Frankel, Gad

المساهمون: Medical Research Council Centre for Molecular Bacteriology and Infection Londres, Royaume-Uni (MRC CMBI), Imperial College London, Division of Cancer Biology Londres, Royaume-Uni, The institute of cancer research London, Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Immunology Rehovot, Israël, Weizmann Institute of Science Rehovot, Israël, This project was supported by grant MR/K019007/1 awarded by the medical research council UK (https://mrc.ukri.orgTest), by grants WT098051 and 107057/Z/15/Z awarded by the Wellcome Trust (https://wellcome.ac.ukTest/) and by grant 695467 – ILC_REACTIVITY awarded by the European Research Council (https://erc.europa.euTest)., European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016)

المصدر: ISSN: 1553-7366.

مصطلحات موضوعية: [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30365535; info:eu-repo/grantAgreement//695467/EU/Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease/ILC_REACTIVITY; inserm-02169323; https://inserm.hal.science/inserm-02169323Test; https://inserm.hal.science/inserm-02169323/documentTest; https://inserm.hal.science/inserm-02169323/file/journal.ppat.1007406.pdfTest; PUBMED: 30365535; PUBMEDCENTRAL: PMC6221368

الإتاحة: https://doi.org/10.1371/journal.ppat.1007406Test
https://inserm.hal.science/inserm-02169323Test
https://inserm.hal.science/inserm-02169323/documentTest
https://inserm.hal.science/inserm-02169323/file/journal.ppat.1007406.pdfTest

المؤلفون: Gonçalves, Pedro, Araujo, João Ricardo, Di Santo, James P

المساهمون: Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Pathogénie microbienne moléculaire, Funding is from a grant to Pedro Gonçalves from the “Labex Milieu Intérieur” ANR 10-LBX-69 MI (http://www.milieuinterieur.fr/enTest). Research conducted in the Di Santo laboratory is supported, in part, by grants from the Institut Pasteur, INSERM, ANR (ILC3_MEMORY) and ERC (ILC_REACTIVITY), We thank Antonio Bandeira for the review of the manuscript and discussion, ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010), ANR-15-CE15-0004,ILC3_MEMORY,Les cellules lymphoïdes innées et la mémoire immunologique(2015)

المصدر: ISSN: 1078-0998.

مصطلحات موضوعية: microbiota, immune system, short-chain fatty acids, butyrate, inflammation, inflammatory bowel disease, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29462379; pasteur-02122775; https://hal-pasteur.archives-ouvertes.fr/pasteur-02122775Test; https://hal-pasteur.archives-ouvertes.fr/pasteur-02122775/documentTest; https://hal-pasteur.archives-ouvertes.fr/pasteur-02122775/file/Inflamm%20Bowel%20Dis_Goncalves_2018_post_print.pdfTest; PUBMED: 29462379

الإتاحة: https://doi.org/10.1093/ibd/izx029Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-02122775Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-02122775/documentTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-02122775/file/Inflamm%20Bowel%20Dis_Goncalves_2018_post_print.pdfTest