Severity of self-reported symptoms and psychological burden 6-months after hospital admission for COVID-19
| العنوان: | Severity of self-reported symptoms and psychological burden 6-months after hospital admission for COVID-19 |
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| المؤلفون: | Eloy, Philippine, Tardivon, Coralie, Martin-Blondel, Guillaume, Isnard, Margaux, Le Turnier, Paul, Le Marechal, Marion, Cabié, André, Launay, Odile, Tattevin, Pierre, Senneville, Eric, Ansart, Séverine, Goehringer, François, Chirouze, Catherine, Bousson, Laurane, Laouénan, Cédric, Etienne, Manuel, Nguyen, Duc, Ghosn, Jade, Duval, Xavier |
| المساهمون: | Jonchère, Laurent, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre d'investigation Clinique [CHU Bichat] - Épidémiologie clinique (CIC 1425), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service Maladies infectieuses et tropicales [CHU Toulouse], Pôle Inflammation, infection, immunologie et loco-moteur [CHU Toulouse] (Pôle I3LM Toulouse), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Métropole Savoie [Chambéry], Centre d’Investigation Clinique de Nantes (CIC Nantes), Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre hospitalier universitaire de Nantes (CHU Nantes), Hôpital Hôtel-Dieu [Paris], Centre Hospitalier Universitaire [Grenoble] (CHU), Centre d'Investigation Clinique Antilles-Guyane (CIC - Antilles Guyane), Université des Antilles et de la Guyane (UAG)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pointe-à-Pitre/Abymes [Guadeloupe] -CHU de Fort de France-Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], CIC Cochin Pasteur (CIC 1417), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôtel-Dieu-Groupe hospitalier Broca-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CHU Pontchaillou [Rennes], Centre Hospitalier Gustave Dron [Tourcoing], Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, CHU Rouen, Normandie Université (NU), CHU Bordeaux [Bordeaux], Services de Maladies Infectieuses et Tropicales [CHU Bichat], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP) |
| المصدر: | International Journal of Infectious Diseases International Journal of Infectious Diseases, 2021, 112, pp.247-253. ⟨10.1016/j.ijid.2021.09.011⟩ |
| بيانات النشر: | HAL CCSD, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, MESH: Humans, MESH: Middle Aged, [SDV.IMM] Life Sciences [q-bio]/Immunology, MESH: Self Report, [SDV]Life Sciences [q-bio], COVID-19, MESH: Quality of Life, macromolecular substances, Persistent symptoms, MESH: Hospitals, MESH: Male, MESH: Prospective Studies, [SDV] Life Sciences [q-bio], Sequelae, Risk factors, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, MESH: COVID-19, [SDV.IMM]Life Sciences [q-bio]/Immunology, MESH: SARS-CoV-2, MESH: Cohort Studies, MESH: Female |
| الوصف: | International audience; OBJECTIVES: Few studies have reported clinical COVID-19 sequelae six months (M6) after hospital discharge, but none has studied symptom severity. METHODS: Prevalence and severity of 7 symptoms were estimated until M6 using the self-administered influenza severity scale in COVID-19 hospitalized patients enrolled in the French COVID cohort. Factors associated with severity were assessed by logistic regression. Anxiety, depression and health-related quality of life (HRQL) were also assessed.RESULTS: At M6, among the 324 patients (median age 61 years, 63% men, 19% admitted to intensive care during the acute phase), 187/324 (58%) reported at least one symptom mostly fatigue (47%) and myalgia (23%). Symptom severity was scored, at most, mild in 125 (67%), moderate in 44 (23%) and severe in 18 (10%). Female gender was the sole factor associated with moderate/severe symptom reporting (OR = 1.98, 95%CI=1.13-3.47). Among the 225 patients with psychological assessment, 24 (11%) had anxiety, 18 (8%) depressive symptoms, and their physical HRQL was significantly poorer than the general population (p=0.0005). CONCLUSION: Even if 58% of patients reported ≥1 symptom at M6, less than 7% rated any symptom as severe. Assessing symptoms severity could be helpful to identify patients requiring appropriate medical care. Women may require special attention. |
| اللغة: | English |
| تدمد: | 1201-9712 1878-3511 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=od______1398::eb55cf5590b6befe4d3bc2085617d997Test https://hal.science/hal-03369814Test |
| رقم الانضمام: | edsair.od......1398..eb55cf5590b6befe4d3bc2085617d997 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 12019712 18783511 |
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