CyberKnife® M6™: Peripheral dose evaluation for brain treatments
| العنوان: | CyberKnife® M6™: Peripheral dose evaluation for brain treatments |
|---|---|
| المؤلفون: | Joël Castelli, Caroline Lafond, J.-P. Manens, F. Jouyaux, J. Bellec, N. Delaby, J. Bouvier, I. Lecouillard, M. Perdrieux |
| المساهمون: | Service de radiothérapie, CRLCC Eugène Marquis (CRLCC), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| المصدر: | Physica Medica Physica Medica, Elsevier, 2017, 37, pp.88-96. ⟨10.1016/j.ejmp.2017.04.015⟩ Physica Medica, 2017, 37, pp.88-96. ⟨10.1016/j.ejmp.2017.04.015⟩ |
| بيانات النشر: | HAL CCSD, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, Biophysics, General Physics and Astronomy, Radiosurgery, 030218 nuclear medicine & medical imaging, law.invention, Stereotactic radiotherapy, 03 medical and health sciences, 0302 clinical medicine, law, In vivo, Cyberknife, In vivo measurements, Medicine, Humans, Radiology, Nuclear Medicine and imaging, Pituitary Neoplasms, Stereotactic radiosurgery, Dosimeter, Peripheral dose, business.industry, Brain Neoplasms, Phantoms, Imaging, Radiotherapy Planning, Computer-Assisted, Collimator, Radiotherapy Dosage, General Medicine, Patient specific, CyberKnife M6™, Peripheral, 030220 oncology & carcinogenesis, Female, [SDV.IB]Life Sciences [q-bio]/Bioengineering, Nuclear medicine, business |
| الوصف: | Purpose This study evaluates the peripheral dose (PD) delivered to healthy tissues for brain stereotactic radiotherapy treatments (SRT) performed with a CyberKnife M6™ Robotic Radiosurgery System and proposes a model to estimate PD before treatment. Method PD was measured with thermoluminescent dosimeters. Measurements were performed to evaluate the influence of distance, collimator type (fixed or Iris™) and aperture size on PD for typical brain treatment plans simulated on an anthropomorphic phantom. A model to estimate PD was defined by fitting functions to these measurements. In vivo measurements were subsequently performed on 30 patients and compared to the model-predicted PD. Results PD (in cGy) was about 0.06% of MU at 15 cm for a 20 mm fixed collimator and 0.04% of MU for the same aperture with Iris™ collimator. In vivo measurements showed an average thyroid dose of 55 mGy (σ = 18.8 mGy). Computed dose for thyroid, breast, umbilicus and gonads showed on average a relative difference of 3.4% with the in vivo dose (σ = 12.4%). Conclusion PD at the thyroid with Iris™ was about a third lower than with a fixed collimator in case of brain SRT. Despite uncertainties (use of anthropomorphic PD to estimate patient specific PD, surface PD to estimate OAR PD) the model allows PD to be estimated without in vivo measurements. This method could be used to optimise PD with different planning strategies. |
| اللغة: | English |
| تدمد: | 1120-1797 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63377dc2df5a5463687d43c0085ac40Test https://hal-univ-rennes1.archives-ouvertes.fr/hal-01534149Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....f63377dc2df5a5463687d43c0085ac40 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 11201797 |
|---|