نتائج البحث - "/dk/atira/pure/subjectarea/asjc/1300/1312"

1

دورية أكاديمية

Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3

المؤلفون: Röth, Sascha, Kocaturk, Nur Mehpare, Sathyamurthi, Preethi S., Carton, Bill, Watt, Matthew, Macartney, Thomas J., Chan, Kwok-Ho, Isidro-Llobet, Albert, Konopacka, Agnieszka, Queisser, Markus A., Sapkota, Gopal P.

المصدر: Röth , S , Kocaturk , N M , Sathyamurthi , P S , Carton , B , Watt , M , Macartney , T J , Chan , K-H , Isidro-Llobet , A , Konopacka , A , Queisser , M A & Sapkota , G P 2023 , ' Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3 ' , Cell Chemical Biology , vol. 30 , no. 10 , pp. 1261-1276.e7 . https://doi.org/10.1016/j.chembiol.2023.07.006Test

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/cce1c275-76ee-4fb5-93f7-4f392856e213Test

الإتاحة: https://doi.org/10.1016/j.chembiol.2023.07.006Test
https://discovery.dundee.ac.uk/en/publications/cce1c275-76ee-4fb5-93f7-4f392856e213Test
https://discovery.dundee.ac.uk/ws/files/115194467/PIIS2451945623002337.pdfTest
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2

دورية أكاديمية

Swietenine Alleviates Nonalcoholic Fatty Liver Disease in Diabetic Mice via Lipogenesis Inhibition and Antioxidant Mechanisms

المؤلفون: Mak, Kit-kay, Zhang, Shiming, Chellian, Jestin, Mohd, Zulkefeli, Epemolu, Ola, Dinkova-Kostova, Albena T., Balijepalli, Madhu Katyayani, Pichika, Mallikarjuna Rao

المصدر: Mak , K , Zhang , S , Chellian , J , Mohd , Z , Epemolu , O , Dinkova-Kostova , A T , Balijepalli , M K & Pichika , M R 2023 , ' Swietenine Alleviates Nonalcoholic Fatty Liver Disease in Diabetic Mice via Lipogenesis Inhibition and Antioxidant Mechanisms ' , Antioxidants , vol. 12 , no. 3 , 595 . https://doi.org/10.3390/antiox12030595Test

مصطلحات موضوعية: swietenine, swietenia macrophylla, diabetes, NAFLD, lipogenesis, NRF2, oxidative stress, /dk/atira/pure/subjectarea/asjc/1100/1106, name=Food Science, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1314, name=Physiology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/6bb6fc74-d311-4167-8168-d642150ab775Test

الإتاحة: https://doi.org/10.3390/antiox12030595Test
https://discovery.dundee.ac.uk/en/publications/6bb6fc74-d311-4167-8168-d642150ab775Test
https://discovery.dundee.ac.uk/ws/files/97178915/antioxidants_12_00595_v2.pdfTest
http://www.scopus.com/inward/record.url?scp=85151549436&partnerID=8YFLogxKTest

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3

دورية أكاديمية

An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation

المؤلفون: Simpson, Luke M., Fulcher, Luke J., Sathe, Gajanan, Brewer, Abigail, Zhao, Jin-Feng, Squair, Daniel R., Crooks, Jennifer, Wightman, Melanie, Wood, Nicola T., Gourlay, Robert, Varghese, Joby, Soares, Renata F., Sapkota, Gopal P.

المصدر: Simpson , L M , Fulcher , L J , Sathe , G , Brewer , A , Zhao , J-F , Squair , D R , Crooks , J , Wightman , M , Wood , N T , Gourlay , R , Varghese , J , Soares , R F & Sapkota , G P 2023 , ' An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation ' , Cell Chemical Biology , vol. 30 , no. 2 , pp. 188-202 . https://doi.org/10.1016/j.chembiol.2023.01.003Test

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/b0ee5ed6-6d18-4e15-bd77-1c5b5ba96ccaTest

الإتاحة: https://doi.org/10.1016/j.chembiol.2023.01.003Test
https://discovery.dundee.ac.uk/en/publications/b0ee5ed6-6d18-4e15-bd77-1c5b5ba96ccaTest
https://discovery.dundee.ac.uk/ws/files/96764889/1_s2.0_S2451945623000260_main.pdfTest
http://www.scopus.com/inward/record.url?scp=85148030514&partnerID=8YFLogxKTest

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4

دورية أكاديمية

Target protein localization and its impact on PROTAC-mediated degradation

المؤلفون: Simpson, Luke M., Glennie, Lorraine, Brewer, Abigail, Zhao, Jin-Feng, Crooks, Jennifer, Shpiro, Natalia, Sapkota, Gopal P.

المصدر: Simpson , L M , Glennie , L , Brewer , A , Zhao , J-F , Crooks , J , Shpiro , N & Sapkota , G P 2022 , ' Target protein localization and its impact on PROTAC-mediated degradation ' , Cell Chemical Biology , vol. 29 , no. 10 , pp. 1482-1504.e7 . https://doi.org/10.1016/j.chembiol.2022.08.004Test

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/1b78f0bd-7662-418b-a4d9-33149454ca2aTest

الإتاحة: https://doi.org/10.1016/j.chembiol.2022.08.004Test
https://discovery.dundee.ac.uk/en/publications/1b78f0bd-7662-418b-a4d9-33149454ca2aTest
https://discovery.dundee.ac.uk/ws/files/80555670/PIIS2451945622003129.pdfTest
http://www.scopus.com/inward/record.url?scp=85140068494&partnerID=8YFLogxKTest

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5

دورية أكاديمية

Antioxidants in Pregnancy:Do We Really Need More Trials?

المؤلفون: Di Fabrizio, Carolina, Giorgione, Veronica, Khalil, Asma, Murdoch, Colin E.

المصدر: Di Fabrizio , C , Giorgione , V , Khalil , A & Murdoch , C E 2022 , ' Antioxidants in Pregnancy : Do We Really Need More Trials? ' , Antioxidants , vol. 11 , no. 5 , 812 . https://doi.org/10.3390/antiox11050812Test

مصطلحات موضوعية: antioxidants, oxidative stress, preeclampsia, pregnancy, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1314, name=Physiology, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/33deba1c-8e32-494e-945b-5eab2c3a32c3Test

الإتاحة: https://doi.org/10.3390/antiox11050812Test
https://discovery.dundee.ac.uk/en/publications/33deba1c-8e32-494e-945b-5eab2c3a32c3Test
https://discovery.dundee.ac.uk/ws/files/74498585/antioxidants_11_00812.pdfTest
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6

دورية أكاديمية

Targeting Epigenetic Modulators Using PROTAC Degraders:Current Status and Future Perspective

المؤلفون: Webb, Thomas, Craigon, Conner, Ciulli, Alessio

المصدر: Webb , T , Craigon , C & Ciulli , A 2022 , ' Targeting Epigenetic Modulators Using PROTAC Degraders : Current Status and Future Perspective ' , Bioorganic & Medicinal Chemistry Letters , vol. 63 , 128653 . https://doi.org/10.1016/j.bmcl.2022.128653Test

مصطلحات موضوعية: Chromatin, Degraders, Epigenetics, GNJIONZKYKHKNJ-UHFFFAOYSA-N, HDCCMCFIGHIDJR-TUDDPRDOSA-N, IJHBBPTVQYEAGQ-MSDWBBBCSA-N, ILVRLRGBSSFKIE-UHFFFAOYSA-N, IVARZBJJMMUJHI-SQKKEFIPSA-N, LONVYJSHGSZBQY-UHFFFAOYSA-N, Multiprotein complexes, PROTACs, Targeted protein degradation, Therapeutics, XQVSBRMMLVXWSD-UHFFFAOYSA-N, YABKDZZQDGCZTF-YUIXOWAOSA-N, ZAGCLFXBHOXXEN-JPTLTNPLSA-N, ZGCCNKFVHQHHRK-ZWHPVRQASA-N, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/3000/3003, name=Pharmaceutical Science, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/subjectarea/asjc/1600/1605

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/a396bb08-21d7-4acd-92ad-b99077eb10fcTest

الإتاحة: https://doi.org/10.1016/j.bmcl.2022.128653Test
https://discovery.dundee.ac.uk/en/publications/a396bb08-21d7-4acd-92ad-b99077eb10fcTest
https://discovery.dundee.ac.uk/ws/files/73258206/1_s2.0_S0960894X22001299_main.pdfTest
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7

دورية أكاديمية

(-)-Epicatechin and its colonic metabolite hippuric acid protect against dexamethasone-induced atrophy in skeletal muscle cells

المؤلفون: Edwards, Sophie J., Carter, Steven, Nicholson, Thomas, Allen, Sophie Louise, Morgan, Paul T., Jones, Simon Wyn, Rendeiro, Catarina, Breen, Leigh

المصدر: Edwards , S J , Carter , S , Nicholson , T , Allen , S L , Morgan , P T , Jones , S W , Rendeiro , C & Breen , L 2022 , ' (-)-Epicatechin and its colonic metabolite hippuric acid protect against dexamethasone-induced atrophy in skeletal muscle cells ' , Journal of Nutritional Biochemistry , vol. 110 , 109150 . https://doi.org/10.1016/j.jnutbio.2022.109150Test

مصطلحات موضوعية: dexamethasone, epicatechin, flavanols, hippuric acid, mitochondria, Muscle atrophy, /dk/atira/pure/subjectarea/asjc/2700/2712, name=Endocrinology, Diabetes and Metabolism, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/2900/2916, name=Nutrition and Dietetics, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

العلاقة: https://researchportal.bath.ac.uk/en/publications/56d4d5e1-ddcf-425d-a557-19c6dfd95b77Test

الإتاحة: https://doi.org/10.1016/j.jnutbio.2022.109150Test
https://researchportal.bath.ac.uk/en/publications/56d4d5e1-ddcf-425d-a557-19c6dfd95b77Test
http://www.scopus.com/inward/record.url?scp=85138771346&partnerID=8YFLogxKTest

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8

دورية أكاديمية

Shedding a New Light on Skin Aging, Iron- and Redox-Homeostasis and Emerging Natural Antioxidants

المؤلفون: Pourzand, Charareh, Albieri-Borges, Andrea, Raczek, Nico N.

المصدر: Pourzand , C , Albieri-Borges , A & Raczek , N N 2022 , ' Shedding a New Light on Skin Aging, Iron- and Redox-Homeostasis and Emerging Natural Antioxidants ' , Antioxidants , vol. 11 , no. 3 , 471 . https://doi.org/10.3390/antiox11030471Test

مصطلحات موضوعية: Aging, Anti-aging, Antioxidant, Photoaging, Photoprotection, Redox, Skin, Sunlight, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1314, name=Physiology, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology

العلاقة: https://researchportal.bath.ac.uk/en/publications/2fc4d0c9-88f3-4a11-9e5d-874ca862fb3dTest

الإتاحة: https://doi.org/10.3390/antiox11030471Test
https://researchportal.bath.ac.uk/en/publications/2fc4d0c9-88f3-4a11-9e5d-874ca862fb3dTest
http://www.scopus.com/inward/record.url?scp=85125258152&partnerID=8YFLogxKTest

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9

دورية أكاديمية

Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis

المؤلفون: Libardo, M. Daben J, Duncombe, Caroline J., Green, Simon R., Wyatt, Paul G., Thompson, Stephen, Ray, Peter C., Ioerger, Thomas R., Oh, Sangmi, Goodwin, Michael B., Boshoff, Helena I. M., Barry III, Clifton E.

المصدر: Libardo , M D J , Duncombe , C J , Green , S R , Wyatt , P G , Thompson , S , Ray , P C , Ioerger , T R , Oh , S , Goodwin , M B , Boshoff , H I M & Barry III , C E 2021 , ' Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis ' , Cell Chemical Biology , vol. 28 , no. 8 , pp. 1180-1191.e20 . https://doi.org/10.1016/j.chembiol.2021.02.023Test

مصطلحات موضوعية: tuberculosis, drug mechanism of action, pro-drug, tryptophan metabolism, antimetabolite, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/0a2339ec-4429-49c5-a052-1a47caae007dTest

الإتاحة: https://doi.org/10.1016/j.chembiol.2021.02.023Test
https://discovery.dundee.ac.uk/en/publications/0a2339ec-4429-49c5-a052-1a47caae007dTest
https://discovery.dundee.ac.uk/ws/files/57600215/1_s2.0_S2451945621001082_main.pdfTest
http://www.scopus.com/inward/record.url?scp=85112587717&partnerID=8YFLogxKTest

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10

دورية أكاديمية

Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation

المؤلفون: Hsu, Yaw Wen, Hsu, Fu Fei, Chiang, Ming Tsai, Tsai, Dong Lin, Li, Fu An, Angata, Takashi, Crocker, Paul R., Chau, Lee Young

المصدر: Hsu , Y W , Hsu , F F , Chiang , M T , Tsai , D L , Li , F A , Angata , T , Crocker , P R & Chau , L Y 2021 , ' Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation ' , Journal of Biomedical Science , vol. 28 , 5 . https://doi.org/10.1186/s12929-020-00698-zTest

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/1c85b323-5582-49aa-9165-1b3bfaeeb0f5Test

الإتاحة: https://doi.org/10.1186/s12929-020-00698-zTest
https://discovery.dundee.ac.uk/en/publications/1c85b323-5582-49aa-9165-1b3bfaeeb0f5Test
https://discovery.dundee.ac.uk/ws/files/55891931/s12929_020_00698_z.pdfTest
http://www.scopus.com/inward/record.url?scp=85098645977&partnerID=8YFLogxKTest

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