دورية أكاديمية
Effect of dietary tall oil fatty acids and hydrolysed yeast in SNP2-positive and SNP2-negative piglets challenged with F4 enterotoxigenic Escherichia coli
| العنوان: | Effect of dietary tall oil fatty acids and hydrolysed yeast in SNP2-positive and SNP2-negative piglets challenged with F4 enterotoxigenic Escherichia coli |
|---|---|
| المؤلفون: | Middelkoop, Anouschka, Kettunen, Hannele, Guan, Xiaonan, Vuorenmaa, Juhani, Tichelaar, Ramon, Gambino, Michela, Rydal, Martin Peter, Molist, Francesc |
| المصدر: | Middelkoop , A , Kettunen , H , Guan , X , Vuorenmaa , J , Tichelaar , R , Gambino , M , Rydal , M P & Molist , F 2024 , ' Effect of dietary tall oil fatty acids and hydrolysed yeast in SNP2-positive and SNP2-negative piglets challenged with F4 enterotoxigenic Escherichia coli ' , Scientific Reports , vol. 14 , no. 1 , 2060 . https://doi.org/10.1038/s41598-024-52586-3Test |
| سنة النشر: | 2024 |
| المجموعة: | Architecture, Design and Conservation - Danish Portal for Artistic and Scientific Research: Research Outputs / Arkitektur, Design og Konservering - Dansk portal for forskning og KUV: Publikationer |
| مصطلحات موضوعية: | /dk/atira/pure/researchoutput/artisticdevelopment/no, name=No |
| الوصف: | Reduction of post-weaning diarrhoea caused by ETEC is a principal objective in pig farming in terms of welfare benefits. This study determined the effects of genetic susceptibility and dietary strategies targeting inflammation and fimbriae adherence on F4-ETEC shedding and diarrhoea in weaned piglets in an experimental challenge model. A DNA marker test targeting single nucleotide polymorphism 2 (SNP2) identified piglets as heterozygous (SNP2+, susceptible) or homozygous (SNP2-, resistant) to developing F4ac-ETEC diarrhoea. A total of 50 piglets, 25 SNP2+ and 25 SNP2-, were weaned at 30 days of age and equally distributed to different treatments (n = 10): Positive control (PC): piglets fed with a negative control diet and provided with colistin via drinking water; Negative control (NC): piglets fed with a negative control diet; Tall oil fatty acids (TOFA): piglets fed with a negative control diet + 1.0 g TOFA/kg feed; Yeast hydrolysate (YH): piglets fed with a negative control diet + 1.5 g YH/kg feed derived from Saccharomyces cerevisiae; and Combination (COM): piglets fed with a negative control diet + 1.0 g TOFA and 1.5 g YH/kg feed. On day 10 post-weaning, all piglets were infected with F4-ETEC by oral administration. Piglets fed with PC, TOFA, YH or COM had a lower faecal shedding of F4-ETEC than NC piglets (P |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://adk.elsevierpure.com/da/publications/42c04efd-465c-4598-b299-3166e957179cTest |
| DOI: | 10.1038/s41598-024-52586-3 |
| الإتاحة: | https://doi.org/10.1038/s41598-024-52586-3Test https://adk.elsevierpure.com/da/publications/42c04efd-465c-4598-b299-3166e957179cTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.54880D40 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41598-024-52586-3 |
|---|