التفاصيل البيبلوغرافية
| العنوان: |
Aptamers: An Insight for Fisheries Research |
| المؤلفون: |
Amit Ranjan*,Sarvendra Kumar, Ranjeeta Kumari, Kirti Komal and Manish kumar |
| بيانات النشر: |
MedCrave |
| سنة النشر: |
2016 |
| المجموعة: |
MedCrave |
| مصطلحات موضوعية: |
Aptamers, SELEX technique, Antibodies, DNA, RNA, yeast, Trypanosome, oligonucleotides, Temperature, Picomolar range, dyes, Amino acids, Antibiotics, Peptides, Protein, Vitamins |
| الوصف: |
Aptamers are oligonucleotides derived from an In vitro evolution process called SELEX. Now, with the development of SELEX process, the isolation of small oligonucleotides that possess the capacity to recognize various classes of target molecules have been made much easier. Aptamers have been evolved to bind proteins which are associated with a number of disease states.They are oligonucleotides sequences that have the tendency to bind to a wide range of target molecules, such as drugs, proteins or other organic or inorganic molecules with high affinity and specificity. These molecules offer a tough rivalry to the antibody classes in terms of therapeutic and diagnostic applications. Aptamers exhibit significant advantages relative to protein therapeutics in terms of size, synthetic accessibility and modification by medicinal chemistry. Despite these associated advantages aptamers are not used on a massive scale commercially, the aptamer-based diagnostic research is still in its infancy. With the increasing use of aptamers in numerous diagnostics, therapeutics and other such aspects, it is likely that the perception of nucleic acid therapeutics will be changed and that aptamers may form the basis of future therapeutics in aquaculture research |
| نوع الوثيقة: |
review |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| العلاقة: |
http://medcraveonline.com/JAMB/JAMB-04-00081.pdfTest |
| الإتاحة: |
http://medcraveonline.com/JAMB/JAMB-04-00081.pdfTest |
| حقوق: |
http://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.71B9BA1 |
| قاعدة البيانات: |
BASE |
