مراجعة
Balancing benefits and risks in the era of biologics
| العنوان: | Balancing benefits and risks in the era of biologics |
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| المؤلفون: | Adami, Giovanni, Saag, Kenneth G., Chapurlat, Roland D., Guanabens, Nuria, Haugeberg, Glenn, Lems, Willem F., Matijevic, Radmila, Peel, Nicola, Poddubnyy, Denis, GEUSENS, Piet |
| المساهمون: | Poddubnyy, Denis/0000-0002-4537-6015, Adami, Giovanni/0000-0002-8915-0755 |
| بيانات النشر: | SAGE PUBLICATIONS LTD |
| سنة النشر: | 2020 |
| المجموعة: | Document Server@UHasselt (Universiteit Hasselt) |
| مصطلحات موضوعية: | benefit-risk ratio, biologics, denosumab, romosozumab |
| الوصف: | Biologics are substances synthetized from biological sources used in the prevention and treatment of several diseases. Rheumatologists have many years of experience with biologics for the treatment of immune-mediated diseases and osteoporosis. Randomized clinical trials and postmarketing studies have demonstrated that treatment with biologics can result, albeit infrequently, in serious adverse events. To date, several risk mitigation strategies have been identified and implemented. The objective of the present perspective review is to examine the risk mitigation strategies of biologic treatments, with special focus on anti-tumor necrosis factors and denosumab. |
| نوع الوثيقة: | review |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1759-720X 1759-7218 |
| العلاقة: | THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 11 (Art N° UNSP 1759720X19883973); http://hdl.handle.net/1942/30356Test; 11; WOS:000492881100001 |
| DOI: | 10.1177/1759720X19883973 |
| الإتاحة: | https://doi.org/10.1177/1759720X19883973Test http://hdl.handle.net/1942/30356Test |
| حقوق: | Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0Test/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sageTest). ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.D0065F30 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 1759720X 17597218 |
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| DOI: | 10.1177/1759720X19883973 |