| مستخلص: |
Immunology and Drug Therapy of Allergic Skin Diseases. By C.A.F.M. Brunjinzeel-Koomen, E.F. Knol. The book summarizes in 12 chapters totalling 200 pages important aspects of frequent immune mediated skin diseases. The term "allergy" is used according a "European" definition as the book does not restrict itself to IgE-mediated diseases. In addition to IgE-mediated diseases it addresses atopic dematitis, drug reactions, and allergic contact dermatitis, which are mostly based on IgE-independent mechanisms. As suggested by the title, the content is broken into three main topics: pathophysiology, clinics, and therapy. The first topic starts with a classic introduction into the skin immune system by J.D. Bos. This overview also introduces the different factors involved in the inflammation of the skin. Consequently, the following chapters describe the immunologic role of the different cells and their interactions: the T-B-cell system, eosinophils, mast cells, and the basics of cell-cell interactions. [ABSTRACT FROM AUTHOR] |
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