المؤلفون: Lohelaid, Helike, Anttila, Jenni E., Liew, Hock-Kean, Tseng, Kuan-Yin, Teppo, Jaakko, Stratoulias, Vassilis, Airavaara, Mikko

المساهمون: Neuroscience Center, Division of Pharmacology and Pharmacotherapy, Division of Pharmaceutical Chemistry and Technology, Divisions of Faculty of Pharmacy, Helsinki Institute of Sustainability Science (HELSUS), Drug Research Program, Pharmaceutical Spectroscopy and Imaging

مصطلحات موضوعية: ARMET, CDNF, ER stress, IRE1, mesencephalic astrocyte-derived neurotrophic factor, unfolded protein response, XBP1, ENDOPLASMIC-RETICULUM STRESS, NEUROTROPHIC FACTOR MANF, CEREBRAL-ARTERY OCCLUSION, S-METHYL-N, ADULT NEUROGENESIS, O-GLCNACYLATION, MESSENGER-RNA, CELL-DAMAGE, 3112 Neurosciences

وصف الملف: application/pdf

العلاقة: HL was funded by the Academy of Finland (Grant No: 322757), JA was funded under the Academy of Finland PROFI6 project UHBRAIN, and JT was funded by the Academy of Finland (Grant No: 321472). MA was funded by Academy of Finland, 324177, PROFI 5 project FinPharma, Neuroscience Center, HiLIFE, University of Helsinki and Sigrid Juselius Foundation.; Lohelaid , H , Anttila , J E , Liew , H-K , Tseng , K-Y , Teppo , J , Stratoulias , V & Airavaara , M 2022 , ' UPR Responsive Genes Manf and Xbp1 in Stroke ' , Frontiers in Cellular Neuroscience , vol. 16 , 900725 . https://doi.org/10.3389/fncel.2022.900725Test; ORCID: /0000-0002-2026-1609/work/116237804; ORCID: /0000-0002-6885-8666/work/116237936; ORCID: /0000-0003-1022-5572/work/116239387; ORCID: /0000-0002-9724-6589/work/128513867; c56fe8a5-db64-41cf-842d-579da01e4d81; http://hdl.handle.net/10138/346279Test; 000818066200001

الإتاحة: http://hdl.handle.net/10138/346279Test

المؤلفون: Rajkumar, Ravi Philip

المصدر: Brain Sci ; ISSN:2076-3425 ; Volume:14 ; Issue:6

مصطلحات موضوعية: biomarker, brain-derived neurotrophic factor, complementary and alternative medicine, hypothalamic–pituitary–adrenal axis, interleukin-6, major depressive disorder, yoga

العلاقة: https://doi.org/10.3390/brainsci14060543Test; https://pubmed.ncbi.nlm.nih.gov/38928543Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11201983Test/

الإتاحة: https://doi.org/10.3390/brainsci14060543Test
https://pubmed.ncbi.nlm.nih.gov/38928543Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11201983Test/

المؤلفون: Ichimura-Shimizu, Mayuko, Kurrey, Khuleshwari, Miyata, Misaki, Dezawa, Takuya, Tsuneyama, Koichi, Kojima, Masami

المصدر: Biomolecules ; ISSN:2218-273X ; Volume:14 ; Issue:4

مصطلحات موضوعية: MASH, MASLD, animal model, brain-derived neurotrophic factor, fibrosis, hyperphagia, inflammation, metabolic syndrome, steatohepatitis

العلاقة: https://doi.org/10.3390/biom14040444Test; https://pubmed.ncbi.nlm.nih.gov/38672461Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11048455Test/

الإتاحة: https://doi.org/10.3390/biom14040444Test
https://pubmed.ncbi.nlm.nih.gov/38672461Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11048455Test/

المؤلفون: Zhang, Shiyan, Gu, Boya, Zhen, Kai, Du, Liwen, Lv, Yuanyuan, Yu, Laikang

المصدر: Arch Gerontol Geriatr ; ISSN:1872-6976 ; Volume:126

مصطلحات موضوعية: Alzheimer's disease, Brain-derived neurotrophic factor, Exercise, Meta-analysis, Systematic review

العلاقة: https://doi.org/10.1016/j.archger.2024.105538Test; https://pubmed.ncbi.nlm.nih.gov/38878598Test

الإتاحة: https://doi.org/10.1016/j.archger.2024.105538Test
https://pubmed.ncbi.nlm.nih.gov/38878598Test

المؤلفون: Martins, Lucas Athaydes, Schiavo, Aniuska, Paz, Lisiê Valéria, Xavier, Léder Leal, Mestriner, Régis Gemerasca

المصدر: Physiol Behav ; ISSN:1873-507X ; Volume:282

مصطلحات موضوعية: Anxiety, Brain-derived neurotrophic factor, Dopamine, Motor skills, Stress

العلاقة: https://doi.org/10.1016/j.physbeh.2024.114593Test; https://pubmed.ncbi.nlm.nih.gov/38782244Test

الإتاحة: https://doi.org/10.1016/j.physbeh.2024.114593Test
https://pubmed.ncbi.nlm.nih.gov/38782244Test

المؤلفون: Zeiler, Frederick A., McFadyen, Charles, Newcombe, Virginia F. J., Synnot, Anneliese, Donoghue, Emma L., Ripatti, Samuli, Steyerbere, Ewout W., Gruen, Russel L., McAllister, Thomas W., Rosand, Jonathan, Palotie, Aarno, Maas, Andrew I. R., Menon, David K.

المساهمون: Centre of Excellence in Complex Disease Genetics, Samuli Olli Ripatti / Principal Investigator, Biostatistics Helsinki, Institute for Molecular Medicine Finland, Faculty of Medicine, Complex Disease Genetics, Aarno Palotie / Principal Investigator, Genomics of Neurological and Neuropsychiatric Disorders

مصطلحات موضوعية: genetics, living systematic review, outcome, prognosis, traumatic brain injury, NEUROTROPHIC FACTOR BDNF, DELAYED CEREBRAL EDEMA, POSTTRAUMATIC EPILEPSY, COGNITIVE PERFORMANCE, FUNCTIONAL OUTCOMES, EXTERNAL VALIDATION, COMT VAL(158)MET, HEAD-INJURY, ASSOCIATION, MILD, 3112 Neurosciences, 3124 Neurology and psychiatry, 3126 Surgery, anesthesiology, intensive care, radiology

وصف الملف: application/pdf

العلاقة: The authors received funding from the European Union FP 7th Framework program under grant agreement no. 602150 (CENTER-TBI).; Zeiler , F A , McFadyen , C , Newcombe , V F J , Synnot , A , Donoghue , E L , Ripatti , S , Steyerbere , E W , Gruen , R L , McAllister , T W , Rosand , J , Palotie , A , Maas , A I R & Menon , D K 2021 , ' Genetic Influences on Patient-Oriented Outcomes in Traumatic Brain Injury : A Living Systematic Review of Non-Apolipoprotein E Single-Nucleotide Polymorphisms ' , Journal of Neurotrauma , vol. 38 , no. 8 , pp. 1107–1123 . https://doi.org/10.1089/neu.2017.5583Test; ORCID: /0000-0002-2527-5874/work/108863556; 59afa6e8-1874-4d34-bd7a-a32ef2894ee8; http://hdl.handle.net/10138/340770Test; 000474149900001

الإتاحة: http://hdl.handle.net/10138/340770Test

المؤلفون: Mahato, Arun Kumar, Sidorova, Yulia A.

المساهمون: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, Joint Activities, Divisions of Faculty of Pharmacy

مصطلحات موضوعية: rearranged in transfection (RET), neurodegeneration, obesity, cancer, RET agonist, neurorestoration, retinitis pigmentosa, hirschsprung disease, glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs), growth differentiation factor 15 (GDF15), MIDBRAIN DOPAMINERGIC-NEURONS, NEUROTROPHIC FACTOR, GDNF FAMILY, PARKINSONS-DISEASE, LIPID RAFTS, C-RET, FUNCTIONAL RECOVERY, TRANSFORMING GENE, MESSENGER-RNAS, MULLER GLIA, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: This work was financially supported by the Academy of Finland (GA 1325555). Open access funding provided by University of Helsinki.; Mahato , A K & Sidorova , Y A 2020 , ' RET Receptor Tyrosine Kinase : Role in Neurodegeneration, Obesity, and Cancer ' , International Journal of Molecular Sciences , vol. 21 , no. 19 , 7108 . https://doi.org/10.3390/ijms21197108Test; a2f662fa-4776-4faa-bc16-871a19786380; http://hdl.handle.net/10138/326615Test; 000586448400001

الإتاحة: http://hdl.handle.net/10138/326615Test

المؤلفون: Kovaleva, Vera, Saarma, Mart

المساهمون: Institute of Biotechnology, Mart Saarma / Principal Investigator

مصطلحات موضوعية: 3112 Neurosciences, 3124 Neurology and psychiatry, cerebral dopamine neurotrophic factor, endoplasmic reticulum stress, growth factors, mesencephalic astrocyte-derived neurotrophic factor, Parkinson's disease, unfolded protein response, ER-STRESS, NEUROTROPHIC FACTOR, DOWN-REGULATION, ALPHA-SYNUCLEIN, SUBSTANTIA-NIGRA, EXPERIMENTAL-MODELS, RAT MODEL, UNFOLDED-PROTEIN-RESPONSE, MIDBRAIN DOPAMINE NEURONS, CDNF PROTECTS

وصف الملف: application/pdf

العلاقة: Kovaleva , V & Saarma , M 2021 , ' Endoplasmic Reticulum Stress Regulators : New Drug Targets for Parkinson's Disease ' , Journal of Parkinson's disease , vol. 11 , no. s2 , pp. S219-S228 . https://doi.org/10.3233/jpd-212673Test; ORCID: /0000-0001-5543-7160/work/101505229; 85116002157; c184da60-991a-4e94-9028-71ad078963f0; http://hdl.handle.net/10138/335297Test; 000700845400013

الإتاحة: http://hdl.handle.net/10138/335297Test

المؤلفون: Bondarenko, Olesja, Saarma, Mart

المساهمون: Institute of Biotechnology

مصطلحات موضوعية: Parkinson's disease, brain-derived neurotrophic factor, cerebral dopamine neurotrophic factor, dopamine neurons, endoplasmic reticulum stress, glial cell line-derived neurotrophic factor, nanomedicine, neuroinflammation, GLIAL-CELL-LINE, NERVE GROWTH-FACTOR, DRUG-DELIVERY, GENE-THERAPY, BIODEGRADABLE MICROSPHERES, INTRAPUTAMINAL INFUSION, DOPAMINERGIC-NEURONS, GOLD NANOPARTICLES, PARTIAL MODEL, LESION MODEL, 3112 Neurosciences

وصف الملف: application/pdf

العلاقة: This work was supported by Sigrid Juselius Foundation, European Union's Horizon 2020 Research and Innovation Programme under the Marie Sklodowska-Curie grant agreement no. 835140 and Estonian Research Council grant PUT1015.; Bondarenko , O & Saarma , M 2021 , ' Neurotrophic Factors in Parkinson's Disease : Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain ' , Frontiers in Cellular Neuroscience , vol. 15 , 682597 . https://doi.org/10.3389/fncel.2021.682597Test; ORCID: /0000-0001-5543-7160/work/97270008; ca06ce18-662f-4649-896b-a021e870d57e; http://hdl.handle.net/10138/332491Test; 000661833600001

الإتاحة: http://hdl.handle.net/10138/332491Test

المؤلفون: Shaheryar, Zaib A., Khan, Mahtab A., Adnan, Ch. Sherjeel, Zaidi, Awais Ali, Hänggi, Daniel, Muhammad, Sajjad

المساهمون: HUS Neurocenter, Clinicum, Neurokirurgian yksikkö

مصطلحات موضوعية: neuroinflammation, blood brain barrier, cytokine, brain microvascular endothelial cell, reactive oxidative species, NF-KAPPA-B, NECROSIS-FACTOR-ALPHA, NITRIC-OXIDE SYNTHASE, CENTRAL-NERVOUS-SYSTEM, NEUROTROPHIC FACTOR EXPRESSION, OXIDATIVE STRESS, IFN-GAMMA, ENDOTHELIAL-CELLS, SIGNALING PATHWAY, GROWTH-FACTOR, 3112 Neurosciences, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: Shaheryar , Z A , Khan , M A , Adnan , C S , Zaidi , A A , Hänggi , D & Muhammad , S 2021 , ' Neuroinflammatory Triangle Presenting Novel Pharmacological Targets for Ischemic Brain Injury ' , Frontiers in Immunology , vol. 12 , 748663 . https://doi.org/10.3389/fimmu.2021.748663Test; 10edb6e0-e965-4f3f-bcce-89023e013104; http://hdl.handle.net/10138/336967Test; 000709988800001

الإتاحة: http://hdl.handle.net/10138/336967Test