دورية أكاديمية
Homeostasis Meets Motivation in the Battle to Control Food Intake.
| العنوان: | Homeostasis Meets Motivation in the Battle to Control Food Intake. |
|---|---|
| المؤلفون: | Ferrario, C.R., Labouèbe, G., Liu, S., Nieh, E.H., Routh, V.H., Xu, S., O'Connor, E.C. |
| المصدر: | The Journal of neuroscience, vol. 36, no. 45, pp. 11469-11481 |
| سنة النشر: | 2016 |
| المجموعة: | Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
| مصطلحات موضوعية: | Animals, Appetite Regulation/physiology, Body Weight/physiology, Brain/physiology, Eating/physiology, Energy Metabolism/physiology, Homeostasis/physiology, Humans, Motivation/physiology, AGRP, POMC, accumbens, arculate nucleus, dieting, dopamine, ghrelin, glucose, insulin, leptin, orexin, paraventricular thalamic nucleus, reward |
| الوصف: | Signals of energy homeostasis interact closely with neural circuits of motivation to control food intake. An emerging hypothesis is that the transition to maladaptive feeding behavior seen in eating disorders or obesity may arise from dysregulation of these interactions. Focusing on key brain regions involved in the control of food intake (ventral tegmental area, striatum, hypothalamus, and thalamus), we describe how activity of specific cell types embedded within these regions can influence distinct components of motivated feeding behavior. We review how signals of energy homeostasis interact with these regions to influence motivated behavioral output and present evidence that experience-dependent neural adaptations in key feeding circuits may represent cellular correlates of impaired food intake control. Future research into mechanisms that restore the balance of control between signals of homeostasis and motivated feeding behavior may inspire new treatment options for eating disorders and obesity. |
| نوع الوثيقة: | article in journal/newspaper review |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0270-6474 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/27911750; info:eu-repo/semantics/altIdentifier/eissn/1529-2401; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_A6A37D5B2C945; https://serval.unil.ch/notice/serval:BIB_A6A37D5B2C94Test; urn:issn:0270-6474; https://serval.unil.ch/resource/serval:BIB_A6A37D5B2C94.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_A6A37D5B2C945Test |
| DOI: | 10.1523/JNEUROSCI.2338-16.2016 |
| الإتاحة: | https://doi.org/10.1523/JNEUROSCI.2338-16.2016Test https://serval.unil.ch/notice/serval:BIB_A6A37D5B2C94Test https://serval.unil.ch/resource/serval:BIB_A6A37D5B2C94.P001/REF.pdfTest http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_A6A37D5B2C945Test |
| حقوق: | info:eu-repo/semantics/openAccess ; Copying allowed only for non-profit organizations ; https://serval.unil.ch/disclaimerTest |
| رقم الانضمام: | edsbas.C25AD6FE |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 02706474 |
|---|---|
| DOI: | 10.1523/JNEUROSCI.2338-16.2016 |