التفاصيل البيبلوغرافية
العنوان: |
Schistosomiasis vaccines: where do we stand? |
المؤلفون: |
Tebeje, Biniam, Harvie, Marina, You, Hong, Loukas, Alex, McManus, Donald |
بيانات النشر: |
BioMed Central Ltd. |
سنة النشر: |
2016 |
المجموعة: |
BioMed Central |
مصطلحات موضوعية: |
Schistosoma mansoni, Schistosoma haematobium, Schistosoma japonicum, Immune response, Schistosomiasis, Vaccine, Immune protection, Antigen discovery |
الوصف: |
Schistosomiasis, caused mainly by S. mansoni , S. haematobium and S. japonicum, continues to be a serious tropical disease and public health problem resulting in an unacceptably high level of morbidity in countries where it is endemic. Praziquantel, the only drug currently available for treatment, is unable to kill developing schistosomes, it does not prevent re-infection and its continued extensive use may result in the future emergence of drug-resistant parasites. This scenario provides impetus for the development and deployment of anti-schistosome vaccines to be used as part of an integrated approach for the prevention, control and eventual elimination of schistosomiasis. This review considers the present status of candidate vaccines for schistosomiasis, and provides some insight on future vaccine discovery and design. |
نوع الوثيقة: |
review |
اللغة: |
English |
العلاقة: |
http://www.parasitesandvectors.com/content/9/1/528Test |
الإتاحة: |
http://www.parasitesandvectors.com/content/9/1/528Test |
حقوق: |
Copyright 2016 The Author(s). |
رقم الانضمام: |
edsbas.A8255892 |
قاعدة البيانات: |
BASE |