Interleukin(IL-2)投与後に腹水貯留を認めた腎細胞癌の2例 ; Two cases of renal cell carcinoma with ascites after interleukin-2 therapy

التفاصيل البيبلوغرافية
العنوان: Interleukin(IL-2)投与後に腹水貯留を認めた腎細胞癌の2例 ; Two cases of renal cell carcinoma with ascites after interleukin-2 therapy
المؤلفون: 小堀, 豪, 前川, 正信, 牛田, 博, 前川, 信也, 井上, 幸治, 金子, 嘉志, 大森, 孝平, 西村, 一男
المساهمون: Kobori, Go, Maegawa, Masanobu, Ushida, Hiroshi, Maekawa, Shinya, Inoue, Koji, Kaneko, Yoshiyuki, Ohmori, Kouhei, Nishimura, Kazuo
بيانات النشر: 泌尿器科紀要刊行会
سنة النشر: 2002
المجموعة: Kyoto University Research Information Repository (KURENAI) / 京都大学学術情報リポジトリ
مصطلحات موضوعية: Antineoplastic Agents/adverse effects/therapeutic use, Ascites/etiology, Capillary Leak Syndrome/etiology, Carcinoma, Renal Cell/drug therapy, Fatal Outcome, Humans, Interleukin-2/adverse effects/therapeutic use, Kidney Neoplasms/drug therapy, Male, Middle Aged, Multiple Organ Failure/etiology, 494.9
الوصف: 2例とも年齢53歳男.IL-2投与後各々3.5kg, 7.5kgの体重増加と腹部膨満感が出現し, CTで多量の胸・腹水を認めた.症例2は体液貯留により引き起こされた多臓器不全が原因で死亡した.両例とも体液貯留にvascular leak syndromeが関与していた可能性が考えられた ; One of the most common and problematic side effects of interleukin-2 therapy (IL-2) is vascular leak syndrome (VLS). VLS is characterized by an increase in vascular permeability accompanied by extravasation of fluids and proteins from the capillary vessels into the tissues resulting in interstitial edema, weight gain, pleural effusion, ascites in severe form, multiple organ failure. We, herein, report two cases of VLS, which occurred following IL-2 therapy against metastatic renal cell carcinoma. One of them died of multiple organ failure one month after the cessation of IL-2 therapy.
نوع الوثيقة: report
وصف الملف: application/pdf
اللغة: Japanese
تدمد: 0018-1994
العلاقة: http://hdl.handle.net/2433/114782Test; AN00208315; 泌尿器科紀要; 48; 455; 457; Acta urologica Japonica; Hinyokika Kiyo
الإتاحة: http://hdl.handle.net/2433/114782Test
رقم الانضمام: edsbas.91061E5D
قاعدة البيانات: BASE