Radiation therapy at the end of life: a population-based study examining palliative treatment intensity

التفاصيل البيبلوغرافية
العنوان: Radiation therapy at the end of life: a population-based study examining palliative treatment intensity
المؤلفون: Kress, Marie-Adele, Jensen, Roxanne E, Tsai, Huei-Ting, Lobo, Tania, Satinsky, Andrew, Potosky, Arnold L
بيانات النشر: BioMed Central Ltd.
سنة النشر: 2015
المجموعة: BioMed Central
مصطلحات موضوعية: Palliative care, SEER-Medicare, Radiation therapy, Radiotherapy, Radiation oncology, End-of-life care
الوصف: Background To examine factors associated with the use of radiation therapy (RT) at the end of life in patients with breast, prostate, or colorectal cancer. Methods Using data from the Surveillance, Epidemiology, and End Results (SEER) – Medicare database, patients were over age 65 and diagnosed between January 1, 2004 and December 31, 2011 with any stage of cancer when the cause of death, as defined by SEER, was cancer; or with stage 4 cancer, who died of any cause. We employed multiple logistic regression models to identify patient and health systems factors associated with palliative radiation use. Results 50% of patients received RT in the last 6 months of life. RT was used less frequently in older patients and in non-Hispanic white patients. Similar patterns were observed in the last 14 days of life. Chemotherapy use in the last 6 months of life was strongly correlated with receiving RT in the last 6 months (OR 2.72, 95% CI: 2.59-2.88) and last 14 days of life (OR 1.55, 95% CI: 1.40-1.66). Patients receiving RT accrued more emergency department visits, radiographic exams and physician visits (all comparisons p < 0.0001). Conclusions Among patients with breast, colorectal, and prostate cancer, palliative RT use was common. End-of-life RT correlated with end-of-life chemotherapy use, including in the last 14 days of life, when treatment may cause increased treatment burden without improved quality of life. Research is needed optimize the role and timing of RT in palliative care.
نوع الوثيقة: report
اللغة: English
العلاقة: http://www.ro-journal.com/content/10/1/15Test
الإتاحة: http://www.ro-journal.com/content/10/1/15Test
حقوق: Copyright 2015 Kress et al.; licensee BioMed Central.
رقم الانضمام: edsbas.988834A9
قاعدة البيانات: BASE